Case Reports in Gastroenterology最新文献_第6页

Gastrointestinal Bleeding due to Intussuscepted Duodenal Lipoma: A Case Report. 肠套叠性十二指肠脂肪瘤致消化道出血1例。

IF 0.7

Case Reports in Gastroenterology Pub Date : 2026-02-02 eCollection Date: 2026-01-01 DOI: 10.1159/000550678

Sylvia Machann, Eliane Angst, Urs Derungs, Anna Bingisser

{"title":"Gastrointestinal Bleeding due to Intussuscepted Duodenal Lipoma: A Case Report.","authors":"Sylvia Machann, Eliane Angst, Urs Derungs, Anna Bingisser","doi":"10.1159/000550678","DOIUrl":"10.1159/000550678","url":null,"abstract":"Introduction: Duodenal lipomas are rare benign tumors which are typically asymptomatic but may cause significant gastrointestinal symptoms.Case presentation: This case shows an uncommon presentation of duodenal intussusception due to a lipoma in a 65-year-old male patient, presenting with melena, hypotension, and vertigo. Upon investigation, a CT scan revealed a 5.7 × 7.1 cm lipomatous mass in the duodenum. Endoscopy confirmed the presence of associated bleeding. Despite initial management with proton pump inhibitors and blood transfusions, the patient required emergency endoscopic interventions for persistent bleeding. A subsequent laparotomy revealed an intussusception of the lipoma into the second part of the duodenum, thus also affecting the gastric antrum. The patient underwent distal gastrectomy and resection of the first part of the duodenum, followed by Roux-Y reconstruction. Histology showed that the submucosal lipoma originated from the first part of the duodenum.Conclusion: This case highlights the rarity of duodenal lipoma as a cause of duodenal intussusception and emphasizes the diagnostic challenges associated with the identification of this condition in adults. Furthermore, it highlights the importance of an interdisciplinary team approach to manage this rare condition effectively.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"20 1","pages":"54-62"},"PeriodicalIF":0.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13019175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147572359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macroamylasemia in a Two-Year-Old Boy as the First Manifestation of Celiac Disease: A Case Report. 以乳糜泻为首发表现的2岁男孩巨淀粉酶血症1例

IF 0.7

Case Reports in Gastroenterology Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.1159/000550670

Marija Dimitrovska-Ivanova, Elena Simeonovska Joveva, Marija Karakolevska Ilova, Aneta Demerdzieva, Biljana Coneska Jovanova, Snezana Palcevska Kocevska

{"title":"Macroamylasemia in a Two-Year-Old Boy as the First Manifestation of Celiac Disease: A Case Report.","authors":"Marija Dimitrovska-Ivanova, Elena Simeonovska Joveva, Marija Karakolevska Ilova, Aneta Demerdzieva, Biljana Coneska Jovanova, Snezana Palcevska Kocevska","doi":"10.1159/000550670","DOIUrl":"10.1159/000550670","url":null,"abstract":"Introduction: Macroamylasemia is a rare biochemical disorder in which the amylase molecule binds to other macromolecules, most commonly immunoglobulin A or G. The increased molecular weight of this complex reduces renal excretion of the enzyme, resulting in chronically elevated serum amylase levels. It can be associated with various non-pancreatic conditions, including celiac disease. In some reported cases, macroamylasemia resolved with a gluten-free diet. We present a pediatric case in which macroamylasemia was the initial manifestation of celiac disease.Case presentation: A two-year-old boy presented with a 3-month history of abdominal pain, anemia, and constipation. Physical examination revealed paraumbilical tenderness. Laboratory tests showed hypochromic anemia; elevated serum amylase (171 U/L); low serum iron (2.5 µmol/L); vitamin D3 deficiency (15.9 ng/mL), and low urine amylase with an amylase/creatinine clearance ratio below 1%, confirming macroamylasemia. Imaging studies were normal. HLA typing revealed the HLA-DQ2 haplotype. Celiac serology was positive for tissue transglutaminase-IgA (87.55 IE/mL) and endomysial antibody-IgA (1:>100). Duodenal biopsy confirmed Marsh type IIIb histology. A gluten-free diet was initiated alongside iron and vitamin D3 supplementation. Symptoms resolved within 2 months, accompanied by normalization of serum amylase levels and a weight gain of over 1 kg. Vitamin D3 therapy was continued until serum levels normalized.Conclusion: Celiac disease should be considered in patients with unexplained macroamylasemia, even in the absence of classical gastrointestinal symptoms. The primary treatment in such cases is a strict gluten-free diet, which can lead to the normalization of serum amylase levels when macroamylasemia is associated with celiac disease.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"20 1","pages":"40-45"},"PeriodicalIF":0.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12995351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147479560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Diagnostic Dilemma: High-Grade Appendiceal Mucinous Neoplasm Presenting as Acute Appendicitis in a 16-Year-Old Female - Case Report and Literature Review. 诊断困境：16岁女性阑尾高级别黏液性肿瘤表现为急性阑尾炎病例报告及文献复习。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2026-01-13 eCollection Date: 2026-01-01 DOI: 10.1159/000550074

Madhuri Singh, Charusheela Gore, Sushama Gurwale, Jhasnavi Mandala, Apoorva Makan

{"title":"A Diagnostic Dilemma: High-Grade Appendiceal Mucinous Neoplasm Presenting as Acute Appendicitis in a 16-Year-Old Female - Case Report and Literature Review.","authors":"Madhuri Singh, Charusheela Gore, Sushama Gurwale, Jhasnavi Mandala, Apoorva Makan","doi":"10.1159/000550074","DOIUrl":"10.1159/000550074","url":null,"abstract":"Introduction: High-grade appendiceal mucinous neoplasms (HAMNs) are rare mucin-producing epithelial tumors of the appendix, typically seen in middle-aged to elderly individuals. They are defined by high-grade cytologic atypia and complex architecture but without infiltrative invasion. Occurrence in pediatric or adolescent patients is virtually unknown.Case presentation: We report a 16-year-old female who presented with signs and symptoms suggestive of acute appendicitis. Ultrasonography supported the diagnosis. A laparoscopic appendectomy was performed. Gross examination revealed a dilated appendix with mucoid contents. Histopathological evaluation confirmed HAMN confined to the appendix.Conclusion: To our knowledge, this is the second reported case of HAMN in an adolescent. This case underscores the importance of histopathologic evaluation of all appendectomy specimens, even in young patients, due to the possibility of underlying neoplasia.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"20 1","pages":"35-39"},"PeriodicalIF":0.6,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146140657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hepatic Angiosarcoma Associated with Chronic Schistosomiasis in a Patient with Decompensated Cirrhosis: A Rare Case Report. 肝硬化失代偿患者肝血管肉瘤合并慢性血吸虫病：罕见病例报告。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2025-12-24 eCollection Date: 2026-01-01 DOI: 10.1159/000549935

Thaer Swaid, Carl Kassab, Najla Saleh Ben Ghashir, Saeed Husain Al Marzooqi

{"title":"Hepatic Angiosarcoma Associated with Chronic Schistosomiasis in a Patient with Decompensated Cirrhosis: A Rare Case Report.","authors":"Thaer Swaid, Carl Kassab, Najla Saleh Ben Ghashir, Saeed Husain Al Marzooqi","doi":"10.1159/000549935","DOIUrl":"10.1159/000549935","url":null,"abstract":"Introduction: Hepatic angiosarcoma (HA) is a rare endothelial malignancy with poor prognosis. Chronic Schistosoma infection causes periportal fibrosis and portal hypertension, but has not been established as a risk factor for hepatic vascular tumors. We report a case of high-grade HA coexisting with chronic schistosomiasis in a patient presenting with acute decompensated cirrhosis.Case presentation: A 64-year-old Filipino woman with no known chemical exposures presented with progressive abdominal pain, jaundice, ascites, and hepatic encephalopathy. Doppler ultrasound initially suggested Budd-Chiari syndrome, later excluded on advanced imaging. MRI showed multifocal hepatic lesions, and CT demonstrated multiple intra-abdominal hematomas without active bleeding. Liver biopsy confirmed poorly differentiated HA (CD31+/CD34+) and revealed calcified Schistosoma eggs. Her course was complicated by hemorrhagic shock after biopsy and paracentesis, spontaneous bacterial peritonitis, acute kidney injury, and worsening hepatic encephalopathy. She died despite aggressive supportive care.Conclusion: This case illustrates the diagnostic challenges and rapid progression of HA, especially in coagulopathic patients where biopsy carries significant risk. The coexistence of chronic schistosomiasis raises the possibility of parasitic inflammation contributing to hepatic vascular tumorigenesis. HA should be considered among unexplained hepatic masses with atypical imaging and clinical features.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"20 1","pages":"29-34"},"PeriodicalIF":0.6,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12830003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunohistochemical Staining for Disseminated Carcinomatosis of the Bone Marrow in a Patient with Post-Colonoscopy Colorectal Cancer: A Case Report. 结肠镜检查后结直肠癌患者骨髓播散性癌的免疫组织化学染色：1例报告。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1159/000549280

Tomoaki Mochimaru, Kazumasa Kawashima, Michio Onizawa, Yu Watahiki, Yosuke Takahata, Mai Murakami, Kakeru Otomo, Tomoyuki Asano, Shuhei Yoshida, Satoshi Kawana, Naohiko Gunji, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira

{"title":"Immunohistochemical Staining for Disseminated Carcinomatosis of the Bone Marrow in a Patient with Post-Colonoscopy Colorectal Cancer: A Case Report.","authors":"Tomoaki Mochimaru, Kazumasa Kawashima, Michio Onizawa, Yu Watahiki, Yosuke Takahata, Mai Murakami, Kakeru Otomo, Tomoyuki Asano, Shuhei Yoshida, Satoshi Kawana, Naohiko Gunji, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira","doi":"10.1159/000549280","DOIUrl":"10.1159/000549280","url":null,"abstract":"Introduction: The incidence of disseminated carcinomatosis of the bone marrow (DCBM) associated with colorectal cancer is low, but it can rapidly progress and cause even death. A previous study has suggested a relationship between mucin profiles and the prognosis of colorectal cancer. However, there are no reports of mucin staining in cases of DCBM with post-colonoscopy colorectal cancer (PCCRC).Case presentation: A 58-year-old man who had undergone colonoscopy (CS) 1 year ago complained of fatigue and fever. The man was diagnosed with virus-associated hemophagocytic syndrome and received steroid pulse therapy. Despite treatment, his condition deteriorated. 18F-fluorodeoxyglucose positron emission tomography-computed tomography revealed diffuse uptake in the bone marrow. A bone marrow biopsy revealed atypical CK20-positive and CK7-negative cellular nests, suggesting a primary gastrointestinal tumor. Subsequent CS at our hospital revealed a 30-mm type 4 transverse colorectal cancer lesion. Thus, the patient was diagnosed with DCBM associated with PCCRC. The patient died 18 days after his last CS. Mucin staining revealed that the cancer cells were MUC2-positive and MUC5AC-negative. MUC5AC negativity has been associated with poor prognosis in colorectal cancer and may have suggested rapid disease progression.Conclusion: The mucin staining result of MUC5AC negativity suggested rapid disease progression and poor prognosis in this case.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"777-783"},"PeriodicalIF":0.6,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145766996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic Ultrasound-Guided Pelvic Abscess Drainage Especially for Pediatric Patients: A Report of Two Cases. 超声内镜下小儿盆腔脓肿引流术：附2例报告。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2025-12-15 eCollection Date: 2026-01-01 DOI: 10.1159/000550073

Yusaku Yokotani, Hiroaki Kitae, Shun Takakura, Naoaki Akamatsu, Koichi Soga

{"title":"Endoscopic Ultrasound-Guided Pelvic Abscess Drainage Especially for Pediatric Patients: A Report of Two Cases.","authors":"Yusaku Yokotani, Hiroaki Kitae, Shun Takakura, Naoaki Akamatsu, Koichi Soga","doi":"10.1159/000550073","DOIUrl":"10.1159/000550073","url":null,"abstract":"Introduction: Endoscopic ultrasound-guided pelvic abscess drainage (EUS-PAD) was reported for the first time in 2003. However, there were few reports focused on EUS-PAD in pediatric patients beforehand. This procedure is one of the minimally invasive methods of treating pelvic abscess, which is close to the rectum. Here, we report the cases of two pediatric patients who underwent EUS-PAD.Case presentation: Two pediatric patients were referred to our hospital for the treatment of pelvic abscesses associated with appendicitis. Using endoscopic ultrasound (EUS) guidance, a pelvic abscess was identified adjacent to the rectal wall. After successive dilatation through a guidewire during fluoroscopic imaging, the deployment of one or two double pigtail stents was performed. Following successful stent deployment, both patients experienced good courses without any complications. After addressing the consequences of complicated appendicitis, both patients underwent laparoscopic appendectomy, which resulted in favorable postoperative courses.Conclusions: EUS-guided drainage can be considered a safe and effective method for primarily dealing with pelvic abscesses and as an efficacious bridge-to-surgery strategy for pediatric patients.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"20 1","pages":"23-28"},"PeriodicalIF":0.6,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12823109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Denture Ingestion, Gastrointestinal Transit and Subsequent Complications in a 75-Year-Old Male: A Case Report. 75岁男性假牙摄入、胃肠道转运及并发症1例报告。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2025-12-12 eCollection Date: 2025-01-01 DOI: 10.1159/000549436

Terry R Wagner, Sem F Hardon, Frank C den Boer, Jorn P Meekel

{"title":"Denture Ingestion, Gastrointestinal Transit and Subsequent Complications in a 75-Year-Old Male: A Case Report.","authors":"Terry R Wagner, Sem F Hardon, Frank C den Boer, Jorn P Meekel","doi":"10.1159/000549436","DOIUrl":"10.1159/000549436","url":null,"abstract":"Introduction: Foreign body ingestion is a common clinical occurrence, often resolving spontaneously as the object passes through the gastrointestinal tract. We present a unique case of sigmoid perforation with an associated local abscess, successfully managed with sigmoidectomy and direct anastomosis.Case presentation: A 75-year-old male presented to the emergency department after accidentally ingesting his dentures. Conservative management was attempted initially. Four days later, the patient developed abdominal pain. Computed tomography scan revealed signs of perforation, and diagnostic laparoscopy confirmed a sigmoid perforation with a localized abscess. A sigmoidectomy with end-to-end circular stapled anastomosis was performed, during which the dentures were mobilized retrogradely to enable controlled extraction, leading to a full and rapid recovery.Conclusion: This case highlights the potential complications and occasional need for surgery due to ingested foreign bodies and the importance of accurate diagnosis and vigilant monitoring in managing these patients.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"767-772"},"PeriodicalIF":0.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12700593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145755429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Life-Threatening Upper Gastrointestinal Bleeding following Percutaneous Endoscopic Gastrostomy Tube Removal under Traction: A Case Report. 经皮内镜胃造口管牵引下拔除后危及生命的上消化道出血1例报告。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2025-12-04 eCollection Date: 2026-01-01 DOI: 10.1159/000548125

Christopher J Shephard, Xiaomin Ma, Rozemary Karamatic

{"title":"Life-Threatening Upper Gastrointestinal Bleeding following Percutaneous Endoscopic Gastrostomy Tube Removal under Traction: A Case Report.","authors":"Christopher J Shephard, Xiaomin Ma, Rozemary Karamatic","doi":"10.1159/000548125","DOIUrl":"10.1159/000548125","url":null,"abstract":"Introduction: Percutaneous endoscopic gastrostomy (PEG) tubes are commonly used to facilitate long-term enteral nutrition. Selected PEG tubes may be appropriately removed without endoscopic guidance via gentle traction, which is seldom associated with major bleeding sequelae. Rare reports of major upper gastrointestinal (GI) hemorrhage following PEG tube removal have been managed using Foley catheter balloon tamponade or endoscopic over-the-scope clipping. Prompt reinsertion of a PEG tube may also be considered.Case presentation: We present the case of a multi-morbid 73-year-old female who experienced life-threatening hemodynamically unstable upper GI bleeding following traction PEG tube removal, which proved refractory to standard endoscopic measures of adrenaline injection and hemostatic clipping, as well as rotational thromboelastometry-guided correction of consumptive coagulopathy. There was no suitable target for angioembolization. Ultimately, in the context of continued hemodynamically unstable GI bleeding, definitive surgical hemostasis - a mode of intervention not frequently reported for bleeding of this nature - was achieved during emergency laparotomy via complete excision of the PEG tract and wedge excision of the involved stomach wall.Conclusion: Life-threatening hemodynamically unstable GI bleeding rarely complicates traction PEG tube removal. In elderly patients with multiple comorbidities, PEG tract bleeding refractory to standard endotherapy and not targetable by angioembolization can be safely and effectively managed with timely surgical intervention.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"20 1","pages":"16-22"},"PeriodicalIF":0.6,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12810975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145997379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colonic Mucosal Pseudolipomatosis with Hemorrhage: A Case Report of Peracetic Acid-Induced Pathogenesis. 结肠粘膜假性脂肪瘤合并出血：过氧乙酸致发病1例。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2025-11-24 eCollection Date: 2025-01-01 DOI: 10.1159/000548927

Chunxia Wang, Yu Zhong, Rihua Zheng

引用次数: 0

Iatrogenic Intramural Esophageal Dissection in Eosinophilic Esophagitis: A Rare Complication of Diagnostic Endoscopy in a Young Atopic Patient - Case Report and Review. 嗜酸性粒细胞性食管炎的医源性壁内食管夹层：一种罕见的年轻特应性患者内镜诊断并发症-病例报告与回顾。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2025-11-21 eCollection Date: 2025-01-01 DOI: 10.1159/000548860

Thaer Swaid, Layth Hamzeh, Maryam Al Ahmad, Sulaman Magdub, Ishtiaq Ahmed

引用次数: 0