Veterinary Sciences最新文献_第3页

Impact of Toceranib Phosphate and Carprofen on Survival and Quality of Life in Dogs with Inflammatory Mammary Carcinomas. 磷酸托克拉尼和卡洛芬对患有炎性乳腺癌的狗的生存期和生活质量的影响

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-13 DOI: 10.3390/vetsci11090430

Miguel Garcia-de la Virgen, Isabel Del Portillo Miguel, Elisa Maiques, Ignacio Pérez Roger, Enric Poch, Juan Borrego

{"title":"Impact of Toceranib Phosphate and Carprofen on Survival and Quality of Life in Dogs with Inflammatory Mammary Carcinomas.","authors":"Miguel Garcia-de la Virgen, Isabel Del Portillo Miguel, Elisa Maiques, Ignacio Pérez Roger, Enric Poch, Juan Borrego","doi":"10.3390/vetsci11090430","DOIUrl":"https://doi.org/10.3390/vetsci11090430","url":null,"abstract":"Canine inflammatory mammary carcinoma (IMC) is an aggressive and rare type of mammary gland cancer in dogs where vascular endothelial growth factor and cyclooxigenase-2 overexpression usually occur, which contribute to its invasive and angiogenic nature. This study aimed to evaluate the efficacy and safety of a combined treatment regimen of toceranib phosphate and carprofen in dogs with measurable IMC. Fifteen female dogs with histopathologically confirmed IMC were included, undergoing a regimen of toceranib (2.4-2.75 mg/kg PO, three times weekly) and carprofen (4.4 mg/kg/24 h PO). Initial evaluations included physical exams, tumor measurements, complete blood count, biochemistry, urinalysis, three view thoracic radiographs, and abdominal ultrasound. Follow-up assessments of physical condition and quality of life (QOL) were conducted bi-weekly, with tumor response evaluations monthly, using RECIST v1.0 criteria. While no complete or partial responses were observed, 60% of the dogs maintained stable disease, with a median progression-free survival of 76 days and an overall survival of 90 days. Notably, 60% of the dogs showed clinical benefit through improved QOL and disease stabilization. The treatment was well-tolerated, with only grade I/II toxicities reported. Despite limited biological activity against the cancer, this protocol may enhance QOL in dogs with IMC, offering a valuable palliative option.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accurate Preoperative Localization of Thoracolumbar Disc Extrusion in Dogs: A Prospective Controlled Study. 狗胸腰椎间盘突出的术前准确定位：一项前瞻性对照研究。

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-13 DOI: 10.3390/vetsci11090434

William McCartney, Ciprian Ober, Christos Yiapanis

{"title":"Accurate Preoperative Localization of Thoracolumbar Disc Extrusion in Dogs: A Prospective Controlled Study.","authors":"William McCartney, Ciprian Ober, Christos Yiapanis","doi":"10.3390/vetsci11090434","DOIUrl":"https://doi.org/10.3390/vetsci11090434","url":null,"abstract":"Intervertebral disc disease (IVDD) is a very common cause of spinal cord compression in dogs. The errors of human surgeons operating on the wrong level or wrong side is a recognized problem and has been largely analyzed. To date, little information is available regarding these errors in dogs. The objective of this study was to assess the accuracy of disc localization prior to possible surgery for IVDD to ensure the surgeon begins their incision directly over the extruded disc. Eighty-five chondrodystrophic or brachycephalic dogs that presented with IVDD confirmed by CT or MRI scan were included in the study. Two small Backhaus clamps were placed cranial and caudal to the lesion site and a control clamp placed at the wing of the ilium. The main interest was whether the surgeon was able to preoperatively pinpoint the correct site for the surgery. Dorsoventral radiographs were taken to verify by another person if the clamps had been placed in the correct position. If the result was incorrect, the surgeon was asked to try again without knowing that the clamps were incorrect, and another radiograph was taken. This was repeated until the position was correct. The results were recorded as correct or incorrect and the number of attempts were registered. The results suggested no significant trend over time for any of the outcomes examined. There were some slight improvements over time, but none of the results was close to statistical significance. The findings of the study showed that in the thoracolumbar region the surgeon has a higher chance of incorrectly marking the exact site for surgery.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined Genome-Wide Association Study and Haplotype Analysis Identifies Candidate Genes Affecting Growth Traits of Inner Mongolian Cashmere Goats. 结合全基因组关联研究和单倍型分析发现影响内蒙古绒山羊生长性状的候选基因

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-12 DOI: 10.3390/vetsci11090428

Xiaofang Ao, Youjun Rong, Mingxuan Han, Xinle Wang, Qincheng Xia, Fangzheng Shang, Yan Liu, Qi Lv, Zhiying Wang, Rui Su, Yanjun Zhang, Ruijun Wang

{"title":"Combined Genome-Wide Association Study and Haplotype Analysis Identifies Candidate Genes Affecting Growth Traits of Inner Mongolian Cashmere Goats.","authors":"Xiaofang Ao, Youjun Rong, Mingxuan Han, Xinle Wang, Qincheng Xia, Fangzheng Shang, Yan Liu, Qi Lv, Zhiying Wang, Rui Su, Yanjun Zhang, Ruijun Wang","doi":"10.3390/vetsci11090428","DOIUrl":"https://doi.org/10.3390/vetsci11090428","url":null,"abstract":"In this study, genome-wide association analysis was performed on the growth traits (body height, body length, chest circumference, chest depth, chest width, tube circumference, and body weight) of Inner Mongolian cashmere goats (Erlangshan type) based on resequencing data. The population genetic parameters were estimated, haplotypes were constructed for the significant sites, and association analysis was conducted between the haplotypes and phenotypes. A total of two hundred and eighty-four SNPs and eight candidate genes were identified by genome-wide association analysis, gene annotation, and enrichment analysis. The phenotypes of 16 haplotype combinations were significantly different by haplotype analysis. Combined with the above results, the TGFB2, BAG3, ZEB2, KCNJ12, MIF, MAP2K3, HACD3, and MEGF11 functional candidate genes and the haplotype combinations A2A2, C2C2, E2E2, F2F2, I2I2, J2J2, K2K2, N2N2, O2O2, P2P2, R1R1, T1T1, W1W1, X1X1, Y1Y1, and Z1Z1 affected the growth traits of the cashmere goats and could be used as molecular markers to improve the accuracy of early selection and the economic benefits of breeding.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Plant Extracts in Enhancing Nutrition and Health for Dogs and Cats: Safety, Benefits, and Applications. 植物提取物在增强猫狗营养和健康方面的作用：安全性、益处和应用。

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-12 DOI: 10.3390/vetsci11090426

Xinzi Guo, Yifei Wang, Zhaoxuan Zhu, Lian Li

{"title":"The Role of Plant Extracts in Enhancing Nutrition and Health for Dogs and Cats: Safety, Benefits, and Applications.","authors":"Xinzi Guo, Yifei Wang, Zhaoxuan Zhu, Lian Li","doi":"10.3390/vetsci11090426","DOIUrl":"https://doi.org/10.3390/vetsci11090426","url":null,"abstract":"Plant extracts, derived from various natural sources, encompass primary and secondary metabolites, which include plant polysaccharides, polyphenols, alkaloids, flavonoids, glycosides, terpenes, and volatile oils. These compounds exhibit a range of biological activities such as antioxidant, anti-inflammatory, and antimicrobial functions. Currently, polyphenols and other bioactive compounds are being incorporated into the diets of farm animals, fish, and pets to promote health benefits. Despite this, the application and potential of plant extracts in canine and feline nutrition have not been comprehensively explored. Many aspects of the mechanisms underlying the action of these plant metabolites remain to be analyzed and elucidated. Furthermore, leveraging natural plant extracts for the treatment of clinical conditions in dogs and cats is a crucial component of clinical nutrition. Consequently, this review aims to highlight the impact of plant extracts on overall health, gastrointestinal health, immune health, cardiovascular health, redox balance, and pathology in dogs and cats.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracted Plasma Cell-Free DNA Concentrations Are Elevated in Colic Patients with Systemic Inflammation. 患有全身性炎症的绞痛患者血浆中提取的游离 DNA 浓度升高。

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-12 DOI: 10.3390/vetsci11090427

Rosemary L Bayless, Bethanie L Cooper, M Katie Sheats

{"title":"Extracted Plasma Cell-Free DNA Concentrations Are Elevated in Colic Patients with Systemic Inflammation.","authors":"Rosemary L Bayless, Bethanie L Cooper, M Katie Sheats","doi":"10.3390/vetsci11090427","DOIUrl":"https://doi.org/10.3390/vetsci11090427","url":null,"abstract":"Colic is a common and potentially life-threatening condition in horses; in many cases, it remains challenging for clinicians to determine the cause, appropriate treatment, and prognosis. One approach that could improve patient care and outcomes is identification of novel diagnostic and prognostic biomarkers. Plasma cell-free DNA (cfDNA) is a biomarker that shows promise for characterizing disease severity and predicting survival in humans with acute abdominal pain or requiring emergency abdominal surgery. In horses, we recently determined that extracted plasma cfDNA concentrations are elevated in colic patients compared to healthy controls. For this current study, we hypothesized that extracted plasma cfDNA concentrations would be significantly higher in horses with strangulating or inflammatory colic lesions, in colic patients with systemic inflammatory response syndrome (SIRS), and in non-survivors. Cell-free DNA concentrations were measured in extracted plasma samples using a compact, portable Qubit fluorometer. Colic patients that met published criteria for equine SIRS had significantly higher median extracted plasma cfDNA compared to non-SIRS colic patients. There were no significant differences in extracted plasma cfDNA concentrations between other groups of interest. Our data offer early evidence that extracted plasma cfDNA concentration may provide information about systemic inflammation in colic patients, and additional research is warranted to expand on these findings.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review of the Current Status on Ruminant Abortigenic Pathogen Surveillance in Africa and Asia. 非洲和亚洲反刍动物流产病原体监测现状回顾。

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-12 DOI: 10.3390/vetsci11090425

George Peter Semango, Joram Buza

{"title":"Review of the Current Status on Ruminant Abortigenic Pathogen Surveillance in Africa and Asia.","authors":"George Peter Semango, Joram Buza","doi":"10.3390/vetsci11090425","DOIUrl":"https://doi.org/10.3390/vetsci11090425","url":null,"abstract":"Ruminant abortion events cause economic losses. Despite the importance of livestock production for food security and the livelihoods of millions of people in the world's poorest communities, very little is known about the scale, magnitude, or causes of these abortions in Africa and Asia. The aim of this review was to determine the current status of surveillance measures adopted for ruminant abortigenic pathogens in Africa and Asia and to explore feasible surveillance technologies. A systematic literature search was conducted using PRISMA guidelines for studies published between 1 January 1990 and 1 May 2024 that reported epidemiological surveys of abortigenic pathogens Africa and Asia. A meta-analysis was used to estimate the species-specific sero-prevalence of the abortigenic agents and the regions where they were detected. In the systematic literature search, 39 full-text manuscripts were included. The most prevalent abortigenic pathogens with sero-prevalence greater than 10% were BHV-1, Brucella, Chlamydia abortus, Neospora caninum, RVFV, and Waddlia chondrophila in cattle, BVDV in sheep, and RVFV and Toxoplasma gondii in goats in Africa. In Asia, Anaplasma, BHV-1, Bluetongue virus, Brucella, and BVDV were prevalent in cattle, whereas Mycoplasma was important in goats and sheep.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

β-Tocotrienol and δ-Tocotrienol as Additional Inhibitors of the Main Protease of Feline Infectious Peritonitis Virus: An In Silico Analysis. β-生育三烯酚和δ-生育三烯酚作为猫传染性腹膜炎病毒主要蛋白酶的额外抑制剂：硅学分析。

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-11 DOI: 10.3390/vetsci11090424

Manos C Vlasiou, Georgios Nikolaou, Kyriakos Spanoudes, Daphne E Mavrides

引用次数: 0

Longitudinal Baboon (Papio anubis) Neutrophil to Lymphocyte Ratio (NLR), and Correlations with Monthly Sedation Rate and Within-Group Sedation Order. 狒狒（Papio anubis）中性粒细胞与淋巴细胞比率（NLR）的纵向变化，以及与月镇静率和组内镇静顺序的相关性。

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-11 DOI: 10.3390/vetsci11090423

Sarah J Neal, Steven J Schapiro, Elizabeth R Magden

{"title":"Longitudinal Baboon (Papio anubis) Neutrophil to Lymphocyte Ratio (NLR), and Correlations with Monthly Sedation Rate and Within-Group Sedation Order.","authors":"Sarah J Neal, Steven J Schapiro, Elizabeth R Magden","doi":"10.3390/vetsci11090423","DOIUrl":"https://doi.org/10.3390/vetsci11090423","url":null,"abstract":"Neutrophil to lymphocyte ratio (NLR) is a simple marker of stress and inflammation, but there is limited research regarding NLR in nonhuman primates (NHPs), with studies showing associations with longevity, certain medical conditions, and stressful circumstances. Here, we examined baboon NLR longitudinally, and as a function of health parameters. We also examined whether NLR was affected by sedation rate, as well as the order of sedation within a group, given that sedation events during clinical and research practices can induce stress in NHPs. While older adult and geriatric baboon NLR did not differ longitudinally, juvenile and young adult NLR tended to increase, primarily driven by increases in females. Additionally, baboons sedated later within a group showed significantly higher NLRs than those sedated earlier in the process. However, baboons with higher sedation rates per month showed lower NLRs. These data indicate that NLR may be dysregulated in different ways as a function of different types of stress, with sedation order (i.e., acute stress) causing pathological increases in NLR, and sedation rate over time (i.e., chronic stress) causing decreases. Importantly, we propose that NLR, a routinely obtained veterinary measure, has potential utility as a welfare indicator of stress resulting from clinical and research practices, as well as a measure that can inform behavioral management practices and interventions.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Different Photoperiods during Incubation on Post-Hatch Broiler Performance and Stress Response. 孵化期间不同光周期对孵化后肉鸡性能和应激反应的影响

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-09 DOI: 10.3390/vetsci11090418

Yasir Arslan Noor, Muhammad Usman, Usman Elahi, Shahid Mehmood, Muhammad Faisal Riaz, Ehsaan Ullah Khan, Kinza Saleem, Sohail Ahmad

{"title":"Effects of Different Photoperiods during Incubation on Post-Hatch Broiler Performance and Stress Response.","authors":"Yasir Arslan Noor, Muhammad Usman, Usman Elahi, Shahid Mehmood, Muhammad Faisal Riaz, Ehsaan Ullah Khan, Kinza Saleem, Sohail Ahmad","doi":"10.3390/vetsci11090418","DOIUrl":"https://doi.org/10.3390/vetsci11090418","url":null,"abstract":"This study evaluated the subsequent effect of photoperiods during incubation on post-hatch growth and stress response of commercial broiler chickens. A total of 875 Ross 308 broiler breeder (48 weeks of age) eggs were hatched using different durations (0, 4, 8, 12, 16, 20, and 24 h a day) of dichromatic light [green and red (495 to 750 nm); 2700 K; 250 lux; SUNJIE; China] throughout the whole period of incubation. A total of 50 0-day-old hatched straight run broiler chicks from each photoperiod during incubation were used to evaluate subsequent growth performance (feed intake, body weight, and feed conversion ratio); stress parameters (physical asymmetry, tonic immobility, and vocalization,); welfare traits (feather score and gait score); carcass traits (live weight, dressed weight, carcass yield, liver weight, gizzard weight, heart weight, abdominal fat weight, breast weight, and leg weight); and serum chemistry (globulin, total protein, cholesterol, glucose, and uric acid). There were no influences of photoperiod during incubation on post-hatch growth, stress parameters, welfare, and carcass traits. Heart yield was higher in birds incubated under 20 h light than in those from the 16 h light group. Incubation under different lighting durations also altered blood biochemical profile but did not influence serum globulin and cholesterol levels. It was concluded that under experimental conditions, incubation of broiler eggs under different lighting durations did not impact subsequent post-hatch performance (21-35 d).","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IgG Subtype Response against Virulence-Associated Protein A in Foals Naturally Infected with Rhodococcus equi. 自然感染马尾罗患球菌的小马驹对病毒相关蛋白 A 的 IgG 亚型反应

IF 2 2区农林科学

Veterinary Sciences Pub Date : 2024-09-09 DOI: 10.3390/vetsci11090422

Yuya Mizuguchi, Nao Tsuzuki, Marina Dee Ebana, Yasunori Suzuki, Tsutomu Kakuda

{"title":"IgG Subtype Response against Virulence-Associated Protein A in Foals Naturally Infected with Rhodococcus equi.","authors":"Yuya Mizuguchi, Nao Tsuzuki, Marina Dee Ebana, Yasunori Suzuki, Tsutomu Kakuda","doi":"10.3390/vetsci11090422","DOIUrl":"https://doi.org/10.3390/vetsci11090422","url":null,"abstract":"Rhodococcus equi is an intracellular bacterium that causes suppurative pneumonia in foals. T-helper (Th) 1 cells play an important role in the protective response against R. equi. In mice and humans, the directionality of IgG switching reflects the polarization of Th-cell responses, but this has not been fully elucidated in horses. In this 4-year study, we classified R. equi-infected foals into surviving and non-surviving group and investigated differences in IgG subclass response to virulence-associated protein A, the main virulence factor of R. equi, between the groups. IgGa, IgGb, and IgG(T) titers were significantly higher in the non-surviving group compared with the surviving group. The titers of IgGa and IgG(T), IgGb and IgG(T), and IgGa and IgGb, respectively, were positively correlated, and the IgG(T)/IgGb ratio in the non-surviving group was significantly higher than that in the surviving group. The IgG(T) titer tended to increase more than the IgGa and IgGb titers in the non-surviving group compared with the surviving group. Our findings suggest that the IgG(T) bias in IgG subclass responses reflects the immune status, which exacerbates R. equi infection.","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0