Clarisse S Malcher, Fernando A M Petri, Laiza P Arruda, Gabriel A de Aguiar, Gabriel Y Storino, Karina Sonalio, Leonardo T Toledo, Flávio Hirose, Luís Guilherme de Oliveira
{"title":"Health-Economic Impact Attributable to Occurrence of Pleurisy and Pneumonia Lesions in Finishing Pigs.","authors":"Clarisse S Malcher, Fernando A M Petri, Laiza P Arruda, Gabriel A de Aguiar, Gabriel Y Storino, Karina Sonalio, Leonardo T Toledo, Flávio Hirose, Luís Guilherme de Oliveira","doi":"10.3390/vetsci11120668","DOIUrl":"10.3390/vetsci11120668","url":null,"abstract":"<p><p>Respiratory diseases, such as pleurisy and pneumonia, cause significant health and economic losses in pig production. This study evaluated 867 finishing pigs from a farm with a history of respiratory issues, using macroscopic lesion scoring (SPES and CVPC), histopathological analysis, qPCR diagnostics, and economic modeling. Severe pleurisy (scores 3 and 4) was observed in 42.1% of carcasses and was strongly correlated with higher bacterial loads of <i>Mycoplasma hyopneumoniae</i>, <i>Actinobacillus pleuropneumoniae</i>, and <i>Pasteurella multocida</i>. Severe lesions reduced the average daily gain (ADG) and carcass weight, leading to increased production costs and lower profitability. Economic analysis revealed that pigs with higher pleurisy scores incurred an additional cost per kg (USD 1.29 vs. USD 1.32 for milder cases), reduced total revenue by 1.36%, and decreased return on investment (ROI) from 5.33% to 3.90%. These findings emphasize the critical impact of respiratory diseases on profitability and the necessity of robust health management strategies, including vaccination and enhanced biosecurity, to minimize economic losses in swine farming.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda M Murti, Clive C Wilson, Antonio F Pemberton, Tatiana M Corey, Loveness N Dzikiti, John D Elsworth, Calvin B Carpenter
{"title":"Factors That Determine Successful Social Housing of African Green Monkeys (<i>Chlorocebus sabaeus</i>) in Same-Sex Pairs and Trios.","authors":"Amanda M Murti, Clive C Wilson, Antonio F Pemberton, Tatiana M Corey, Loveness N Dzikiti, John D Elsworth, Calvin B Carpenter","doi":"10.3390/vetsci11120667","DOIUrl":"10.3390/vetsci11120667","url":null,"abstract":"<p><p>Social housing provides a high level of enrichment for captive non-human primates, but providing this in research situations can be challenging. We have developed a multifactorial animal selection and introduction process coordinated by veterinary and animal care behavioral teams. This process sought to successfully establish lasting same-sex pairs and trios for African green monkeys (<i>Chlorocebus sabaeus</i>) in studies lasting from three months to over a year. The selection and introduction process addresses variables that impact a successful grouping, including age, animal weight difference, cage size and configuration. Evaluation and consideration of these initial matchmaking parameters has favorably enhanced pairing/trio bonding. Social housing with females has been typically more successful than with males, with 90-100% of females successfully pair- or trio-housed. Successful pairs and trios exhibit multiple affiliative behaviors and demonstrate better overall health while under study, ensuring benefits both to animal welfare and study data.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142897811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Treatment of Renal Cell Carcinoma Associated with Hypertrophic Osteopathy in a Cat.","authors":"Takashi Tanaka, Midori Tanaka, Tomoyuki Tezuka, Kazumi Shimada, Ryo Tanaka","doi":"10.3390/vetsci11120669","DOIUrl":"10.3390/vetsci11120669","url":null,"abstract":"<p><p>An eight-year-old spayed female Abyssinian cat presented with lameness. Palpation revealed swelling, heat, and a reduced range of motion in the stifle and tarsal joints in both hind limbs. A radiographic examination of both hind limbs revealed periosteal proliferation from the distal tibia to the tarsal and metatarsal bones, which suggested hypertrophic osteopathy. Thorax and abdominal radiographic examinations were performed to identify the primary disease. Complete blood count and routine serum biochemistry tests revealed no abnormalities. No obvious anomalies were evident in the thoracic radiograph; however, a mass was observed near the left kidney on an abdominal radiograph. An abdominal ultrasound was performed, which revealed a hypoechoic renal mass located in the caudal pole of the left kidney. The left nephrectomy was performed after exploration of the abdominal cavity confirmed an abnormality in the left kidney. A histopathological examination revealed renal cell carcinoma. The cat was subsequently fed on a renal prescription diet but received no additional treatment. The periosteal lesion in the distal tibia regressed over time, but the lesions remained in the talus and metatarsal bones. At 1670 days following surgery, blood tests indicated that urea nitrogen and creatinine were above the normal range. In addition, urinalysis revealed an isosthenuria. However, the cat survived over 4500 days following surgery.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Induced Pluripotent Stem Cells in Birds: Opportunities and Challenges for Science and Agriculture.","authors":"Nousheen Zahoor, Areej Arif, Muhammad Shuaib, Kai Jin, Bichun Li, Zeyu Li, Xiaomeng Pei, Xilin Zhu, Qisheng Zuo, Yingjie Niu, Jiuzhou Song, Guohong Chen","doi":"10.3390/vetsci11120666","DOIUrl":"10.3390/vetsci11120666","url":null,"abstract":"<p><p>The only cells in an organism that could do any other sort of cell until 2006 (except sperm or egg) were known as embryonic stem cells, ESC [...].</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Farre, Erik Rattenborg, Henk Hogeveen, Volker Krömker, Carsten Thure Kirkeby
{"title":"Dairy Farmers and Veterinarians' Agreement on Communication in Udder Health Consulting.","authors":"Michael Farre, Erik Rattenborg, Henk Hogeveen, Volker Krömker, Carsten Thure Kirkeby","doi":"10.3390/vetsci11120665","DOIUrl":"10.3390/vetsci11120665","url":null,"abstract":"<p><p>Udder health consulting is an essential aspect of mastitis control and is based on herd-specific intervention often provided by the herd veterinarian, focusing on managing the bulk tank somatic cell count. Effective communication and alignment of expectations between dairy farmers and herd veterinarians are more critical than ever due to the substantial increase in herd sizes, which amplifies both potential gains and losses. To facilitate future cooperation between dairy farmers and herd veterinarians, it is important to understand the current level of agreement in communication, and therefore, we conducted a study to describe the agreement in the perception of their communication during udder health consulting. From August 2019 to February 2021, herds (n = 88) were selected to participate in the study, with the herd size ranging from 105 to 1291 milking cows. The dairy farmer and herd veterinarian were encouraged to answer a questionnaire to shed light on their perception of communication during udder health consulting. The agreement between the dairy farmer and herd veterinarian regarding their perception of communication during udder health consulting was initially analyzed using Cohen's weighted kappa. The agreement between farmers and veterinarians ranged from -0.06 and 0.12, indicating that the herd veterinarians' focus is inconsistent with the dairy farmers' preferences. The frequency with which udder health is discussed and how potential problems are identified were associated with a significantly lower BTSCC estimate of 427 cells/mL. In contrast, general cooperation between the dairy farmer and herd veterinarian was associated with an estimated increase of 604 cells/mL in BTSCC.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qingze Meng, Yang Shao, Wei Li, Jia Lu, Xinyue Wang, Liang Deng
{"title":"Evaluation of Serum Lipids, Biochemical Parameters, Selected Antioxidant Elements and Oxidative Stress Profiles in Late Pregnant Jennies with Hyperlipemia.","authors":"Qingze Meng, Yang Shao, Wei Li, Jia Lu, Xinyue Wang, Liang Deng","doi":"10.3390/vetsci11120664","DOIUrl":"10.3390/vetsci11120664","url":null,"abstract":"<p><p>Donkeys are particularly at risk of hyperlipemia. Hyperlipemia is a metabolic disease caused by the mobilization of fatty acids from adipose tissue, which often impacts pregnant and lactating jennies (female donkeys) during periods of negative energy balance. This study aimed to evaluate the levels of lipids, biochemical parameters, selected antioxidant elements and oxidative stress parameters in late pregnant jennies affected by hyperlipemia. Compared with the healthy jennies, the hyperlipemic animals exhibited significantly elevated levels of triglycerides (TGs), total cholesterol (T-CHO) and low-density lipoprotein cholesterol (<i>p</i> < 0.05), coupled with reduced levels of high-density lipoprotein cholesterol and albumin (ALB) (<i>p</i> < 0.05). The serum levels of biochemical parameters related to liver function, such as aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase (AKP) and cholinesterase (CHE), showed a significant increase in the hyperlipemia group compared to the healthy group (<i>p</i> < 0.05). The serum level of selenium was significantly lower (<i>p</i> < 0.05) and positively correlated with TGs (r = 0.85) and ALB (r = 0.73) in the hyperlipemia group. The hyperlipemic jennies showed diminished serum levels of antioxidant capacity and increased levels of malondialdehyde (MDA). The area under the curve values for T-CHO, ALB, AKP, CHE, total superoxide dismutase, glutathione and MDA were relatively high. Thus, our findings reflect metabolic disorders, liver dysfunction and oxidative stress in late pregnant hyperlipemic jennies, providing a basis for the improvement of clinical diagnostic methods and early prevention and control of hyperlipemia in jennies.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuli Guo, Junping Liu, Shuangyi Zhang, Di Sun, Zhiying Dong, Jinshan Cao
{"title":"A Transcriptome Approach Evaluating the Effects of Atractylenolide I on the Secretion of Estradiol and Progesterone in Feline Ovarian Granulosa Cells.","authors":"Yuli Guo, Junping Liu, Shuangyi Zhang, Di Sun, Zhiying Dong, Jinshan Cao","doi":"10.3390/vetsci11120663","DOIUrl":"10.3390/vetsci11120663","url":null,"abstract":"<p><p><i>Atractylodes macrocephala Koidz</i> (AMK) as an oriental medicine has been used in the treatment of threatened abortion. <i>Atractylenolide I</i> (AT-I) is one of the major bioactive components of AMK. This study aimed to investigate the effect of AT-I on the secretion of estradiol (E<sub>2</sub>) and progesterone (P<sub>4</sub>) in feline ovarian granulosa cells (FOGCs), which is necessary for pregnancy. At first, the proliferation of FOGCs after AT-I treatment was measured by CCK-8. Then, the synthesis of E<sub>2</sub> and P<sub>4</sub> were measured by ELISA. Lastly, transcriptome sequencing was used to detect the DEGs in the FOGCs, and RNA-seq results were verified by RT-qPCR and biochemical verification. It was found that AT-I could promote proliferation and the secretion of E<sub>2</sub> and P<sub>4</sub> in FOGCs; after AT-I treatment, 137 significant DEGs were observed, out of which 49 were up-regulated and 88 down-regulated. The DEGs revealed significant enrichment of 52 GO terms throughout the differentiation process (<i>p</i> < 0.05), as deciphered by Gene Ontology enrichment analysis. Kyoto Encyclopedia of Genes and Genomes analysis manifested that the DEGs were successfully annotated as members of 155 pathways, with 23 significantly enriched (<i>p</i> < 0.05). A relatively high number of genes were enriched for the cholesterol metabolism, ovarian steroidogenesis, and biosynthesis of unsaturated fatty acids. Furthermore, the contents of the total cholesterol and low-density lipoprotein cholesterol were decreased by AT-I treatment in the cell culture supernatant. The results indicated that AT-I could increase the ability of FOGCs to secrete E<sub>2</sub> and P<sub>4</sub>, which might be achieved by activation of cholesterol metabolism.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shamim Sarkar, Stephen A Kania, Mohamed A Abouelkhair, Brian Whitlock, Chika C Okafor
{"title":"Residues of Tetracycline, Erythromycin, and Sulfonamides in Beef, Eggs, and Honey from Grocery Stores in Knoxville, Tennessee, USA: Failure of Cooking to Decrease Drug Concentrations.","authors":"Shamim Sarkar, Stephen A Kania, Mohamed A Abouelkhair, Brian Whitlock, Chika C Okafor","doi":"10.3390/vetsci11120660","DOIUrl":"10.3390/vetsci11120660","url":null,"abstract":"<p><p>This study evaluated the concentrations of tetracycline, erythromycin, and sulfonamide in beef, eggs, and honey products sold at grocery stores and whether standard cooking to 160 °F (71 °C) reduced the concentrations of antimicrobials spiked into the evaluated food products. In June 2021, the concentrations of selected antimicrobials in 65 samples (8 beef, 48 eggs, 9 honey samples) purchased from grocery stores within Knoxville, Tennessee, were measured using enzyme-linked immunosorbent assays. The Kruskal-Wallis test was used to assess the differences in the median tetracycline concentrations across food types, while the Mann-Whitney test was used to compare the erythromycin residue concentrations between beef and honey. Linear regression was used to analyze whether standard cooking at 160 °F (71 °C) reduced antimicrobial concentrations. Detectable tetracycline concentrations were found in all beef (8/8, 100%), eggs (46/48, 96%), and honey (9/9, 100%) samples, with median concentrations of 7.73, 5.62, and 13.13 µg/kg, respectively. Honey had significantly higher tetracycline concentrations than eggs (<i>p</i> = 0.002). Detectable erythromycin concentrations were found in beef (5/8, 63%) and honey (9/9, 100%), with median concentrations of 0.14 µg/kg for beef and 0.48 µg/kg for honey. None of the antimicrobial concentrations found in the beef and egg products exceeded the U.S. FDA's maximum residue limits (MRL). Sulfonamide concentrations were undetectable in the beef and egg products. The concentrations of tetracycline, erythromycin, and sulfonamide spiked into the food products did not change significantly in response to cooking to 160 °F (71 °C). The antimicrobial concentrations found in the selected commercial food products were below the MRL, and cooking appeared to not reduce the spiked antimicrobial concentrations in the evaluated food products.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Updating the Relationship Between the Threshold Value of Average Nucleotide Identity and Digital DNA-DNA Hybridization for Reliable Taxonomy of <i>Corynebacterium</i>.","authors":"Haitham Elbir","doi":"10.3390/vetsci11120661","DOIUrl":"10.3390/vetsci11120661","url":null,"abstract":"<p><p>Currently, bacterial classification at the species level relies on the 95-96% average nucleotide identity (ANI) value that is known to be equivalent to a 70% digital DNA-DNA hybridization (dDDH) value. However, during the routine identification of bacteria in the uteri of camels with a history of conception failure, we found that four out of the seven strains (2298A, 2569A, 2652, 2571B, 1103A, 2571A, and 335C) could not be assigned to any valid <i>Corynebacterium</i> species. Furthermore, a 70% dDDH value did not correspond to a 95-96% ANI value in strain 2569A. Thus, we aimed to classify these strains and explain the mechanisms underlying gene repertoire diversity and the disagreement we found between the ANI and dDDH cutoff values. For this study, we extracted information from the genomes of 150 <i>Corynebacterium</i>-type species and seven sequenced genomes of uterine <i>Corynebacterium</i> isolates. We found that the 96.67% OrthoANI value should be used in place of the generally accepted 95-96% ANI threshold in order to obtain an equivalent 70% dDDH value. Phylogenomic analysis determined the evolutionary position of each uterine strain. Then, strains 2652 and 2571B were classified as <i>C. camporealensis</i> based on the ANI value (98.44% and 98.72%) and dDDH value (85.8% and 88.5%). Strain 2569A had a 96.58% ANI and a 69.4% dDDH value and was classified as <i>C. urogenitale.</i> The strains 335C, 1103A, 2571A, and 2298A were classified as novel <i>Corynebacterium</i> based on the ANI value (77.12, 94.01%, 94.26%, and 94.03%) and dDDH value (21.3%, 54.1%, 54.9%, and 51.3%), respectively. Genes for menaquinone biosynthesis and the saturation of chains were detected in uterine strains and their closely related type strains. Gene gain predominates as a source of variation in the gene repertoire. Most of these genes are gained by horizontal gene transfer, driven by genomic islands and prophage. In summary, we refined the ANI cutoff value for an accurate diagnosis of <i>Corynebacterium</i>. Moreover, we clarified the mechanism underlying the diversity of the gene repertoire and expanded the number of <i>Corynebacterium</i> species isolated from the camel uterus.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ibrahim Khalil, Md Abu Sayeed, Mitun Sarkar, Md Nurul Islam, Mozaffar G Osmani, Meherjan Islam, Sharmin Chowdhury, Md Abu Shoieb Mohsin, Md Ahasanul Hoque
{"title":"Web-Based Passive Surveillance: Multifactorial Assessment of Sonali Chicken Diseases and Antimicrobial Prescription Pattern in Bangladesh.","authors":"Ibrahim Khalil, Md Abu Sayeed, Mitun Sarkar, Md Nurul Islam, Mozaffar G Osmani, Meherjan Islam, Sharmin Chowdhury, Md Abu Shoieb Mohsin, Md Ahasanul Hoque","doi":"10.3390/vetsci11120662","DOIUrl":"10.3390/vetsci11120662","url":null,"abstract":"<p><p>Despite the significant growth in Sonali chicken production across Bangladesh, inadequate disease surveillance and control measures along with indiscriminate antimicrobial use remain major challenges to the sector. In this study, we evaluated the disease burden and antimicrobial prescription patterns of Sonali chickens in Bangladesh using a web-based data recording system from 2020 to 2021 and analyzed 1690 cases. The diagnoses recorded in the system were presumptive, as they were based on clinico-epidemiological history, clinical signs, and gross necropsy findings noted by registered veterinarians. We conducted this study in Bogura, a district renowned for its high concentration of Sonali chicken farms. We estimated a higher prevalence of infection among grower chickens (69.0%) compared to starter chickens (31.0%). Small- to medium-sized flocks (63%) were more frequently infected than larger flocks (37.0%). Most disease cases occurred during the summer season (43.0%), followed by winter (27%), the rainy season (15%), and autumn (14%). Overall, climatic factors contributed to 51% of disease occurrence at temperatures below 25°C, 55% at high humidity (≥75%), and 57% during heavy rainfall (≥29 mm). The most prevalent disease was Newcastle disease (ND) (19.5%), followed by Marek's disease (9.8%), coccidiosis (7.4%), necrotic enteritis (4.7%), infectious bursal disease (3.2%), and infectious laryngotracheitis (3.2%). The odds of ND were 1.4 (grower chickens vs. starter chickens), 11.4 (summer vs. winter), 4.1 (autumn vs. winter), 3.9 (rainy vs. winter), 3.5 (≥25 °C vs. <25 °C), and 2.6 (≥75% vs. <75%). Tylvalosin (38.0%) was the most frequently prescribed antibiotic, followed by fluoroquinolones (9.0%), aminoglycosides (8.0%), and colistin sulphate (4.0%). These findings suggest that a web-based disease record could be an important tool for a centralized poultry disease surveillance system in low- and middle-income countries like Bangladesh.</p>","PeriodicalId":23694,"journal":{"name":"Veterinary Sciences","volume":"11 12","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142897829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}