Autopsy and Case Reports最新文献_第4页

Bilateral high origin and superficial trajectory of the deep femoral artery: clinical and applied anatomy. 股深动脉的双侧高起源和浅轨迹：临床和应用解剖学。

Autopsy and Case Reports Pub Date : 2024-06-07 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.492

Gabriel Deveaux, William P Mayer

{"title":"Bilateral high origin and superficial trajectory of the deep femoral artery: clinical and applied anatomy.","authors":"Gabriel Deveaux, William P Mayer","doi":"10.4322/acr.2024.492","DOIUrl":"10.4322/acr.2024.492","url":null,"abstract":"The anatomy of the femoral triangle is explored in various approaches, ranging from pulse verification to invasive catheterization procedures. Within the femoral triangle, the deep femoral artery is one of the vessels reported to present several anatomical variations that must be considered before clinical or surgical interventions. Here, we are reporting a unique bilateral variation of the deep femoral artery for medical education purposes and reflecting on its applied, surgical, and clinical anatomy. During the dissection of the femoral triangle, we observed that the deep femoral artery originated in the vicinity of the inguinal ligament and ran in parallel with the femoral artery in a superficial trajectory on both sides of the donor. On the right side, the DFA continued superficial for 8.8 cm, with an origin of 1.2 cm inferior to the inguinal ligament. On the left side, it presented a similar anatomical arrangement, though with an origin of 1.6cm inferior to the inguinal ligament and a superficial course of 5cm. The position of the lateral circumflex femoral vein posterior to the deep femoral artery played a role in this distinctive, lengthy, and superficial presentation of the deep femoral artery. This anatomical variation directly affects surgical procedures, diagnostics, and endovascular interventions. A deep femoral artery with such a lengthy superficial trajectory can be mistakenly used for catheterization instead of the femoral artery or be injured, disrupting the main blood supply of the thigh muscles.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024492"},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A bleeding heart: case report and review of pericardial angiosarcoma. 一颗流血的心：心包血管肉瘤的病例报告和综述。

Autopsy and Case Reports Pub Date : 2024-05-22 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.488

Ujjwal Madan, Himil Mahadevia, Parth Sharma, Satya Preetham Gunta, Ossama Tawfik, Karen Fritchie, Julian Magadan

{"title":"A bleeding heart: case report and review of pericardial angiosarcoma.","authors":"Ujjwal Madan, Himil Mahadevia, Parth Sharma, Satya Preetham Gunta, Ossama Tawfik, Karen Fritchie, Julian Magadan","doi":"10.4322/acr.2024.488","DOIUrl":"10.4322/acr.2024.488","url":null,"abstract":"Primary cardiac tumors are rare. The cardiac sarcomas are the most common malignant cardiac tumors. These tumors have a dismal prognosis with an overall median survival of 25 months. Clinical features include dyspnea, arrhythmias, pericardial effusions, heart failure, and sudden cardiac death. The diagnosis is often challenging. Therefore, the cardiac imaging workup plays a central role in addition to a high clinical suspicion in the setting of atypical presentations that do not respond to standard therapies. The echocardiography, computed tomography, and cardiac MRI are crucial in clinching the diagnosis. Multimodal treatment with surgery, chemotherapy, and radiotherapy has been shown to improve outcomes, as opposed to using either of these modalities alone. We describe the case of a 30-year-old gentleman with COVID-19 infection who developed recurrent hemorrhagic pericardial effusions refractory to standard treatment and was eventually diagnosed as a case of pericardial angiosarcoma after his biopsy revealed the diagnosis and staging was performed using PET-CT-FDG scan. Our case re-emphasizes the importance of considering a malignant etiology early in the course of the disease presentation, especially in recurrent hemorrhagic effusions despite an inflammatory cytologic diagnosis of fluid. It also highlights the place for cardiac CT and MRI to ascertain the location and spread and to plan the further course of treatment. If diagnosed early, the estimated survival time can be prolonged by instituting a multimodal approach.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024488"},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thrombosis of the vasa vasorum of the large and medium size pulmonary artery and vein leads to pulmonary thromboembolism in COVID-19. 在 COVID-19 中，大、中型肺动脉和静脉的血管栓塞导致肺血栓栓塞。

Autopsy and Case Reports Pub Date : 2024-05-22 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.491

Hubert Daisley, Oneka Acco, Martina Daisley, Dennecia George, Lilly Paul, Errol James, Arlene Rampersad, Farhaana Narinesingh, Ornella Humphrey, Johann Daisley, Melissa Nathan

引用次数: 0

Acute liver failure caused by lymphocyte-depleted Hodgkin lymphoma in tuberculosis and HIV-infected patient. 肺结核和艾滋病病毒感染者淋巴细胞耗竭性霍奇金淋巴瘤引起的急性肝功能衰竭。

Autopsy and Case Reports Pub Date : 2024-05-22 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.490

Mayur Parkhi, Madhumita Premkumar, Amanjit Bal, Ashim Das, Sanjay Jain, Suvradeep Mitra

{"title":"Acute liver failure caused by lymphocyte-depleted Hodgkin lymphoma in tuberculosis and HIV-infected patient.","authors":"Mayur Parkhi, Madhumita Premkumar, Amanjit Bal, Ashim Das, Sanjay Jain, Suvradeep Mitra","doi":"10.4322/acr.2024.490","DOIUrl":"10.4322/acr.2024.490","url":null,"abstract":"The lymphocyte-depleted classic Hodgkin lymphoma (LDCHL), the rarest subtype of classic Hodgkin lymphoma (CHL), is usually diagnosed at an advanced stage (stage IV) and one that unusually involves the liver, causing a rapidly progressive clinical course. We describe a 40-year-old immunocompromised man presenting with a progressive non-cholestatic jaundice and intermittent fever. The abdominal ultrasonography revealed a nodular liver with coarse echotexture and periportal hypodensities. The thoracic and abdominal contrast-enhanced computed tomography revealed right cervical and paraaortic lymphadenopathy, hepatosplenomegaly, diffuse mural thickening of duodenal and jejunal loops, and bilateral lobulated kidneys. Subsequently, he succumbed to his illness secondary to refractory septic shock. On postmortem examination, he was diagnosed with classic Hodgkin lymphoma (lymphocyte-depleted type) involving paraaortic and mediastinal lymph nodes based on morphology and immunochemistry findings. The lymphomatous process involved the liver (causing multiacinar confluent hepatic necrosis) and spleen, both showing tuberculous foci. This autopsy case depicts an uncommon case of acute liver failure due to infiltration of the liver by LDCHL in an HIV-infected patient. The findings of angiotropism and angioinvasion establish the pathological mechanism of liver failure (hepatocellular necrosis) in such cases.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024490"},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141159361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esophageal Melanocytosis. 食道黑色素细胞增多症

Autopsy and Case Reports Pub Date : 2024-05-22 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.487

Samikshya Thapa, Gajendra Kumar Yadav, Ratna Mondal, Ravi Hari Phulware

引用次数: 0

Sudden pediatric death unveiling pulmonary arteriovenous malformations. 小儿猝死揭秘肺动静脉畸形

Autopsy and Case Reports Pub Date : 2024-05-22 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.489

Hadeel Abu-El-Rub, Rashed Shatnawi, Yahia I AbuZetun, Doaa Ghorab, Ali M Shotar

{"title":"Sudden pediatric death unveiling pulmonary arteriovenous malformations.","authors":"Hadeel Abu-El-Rub, Rashed Shatnawi, Yahia I AbuZetun, Doaa Ghorab, Ali M Shotar","doi":"10.4322/acr.2024.489","DOIUrl":"10.4322/acr.2024.489","url":null,"abstract":"Pulmonary arteriovenous malformations (PAVMs) are abnormal vascular connections between pulmonary arteries and veins, often associated with hereditary hemorrhagic telangiectasia (HHT). Most PAVMs are asymptomatic, but life-threatening complications like pulmonary hemorrhage, brain abscesses, and paradoxical emboli can emerge, so prompt diagnosis and treatment are crucial. We report a case of sudden pediatric death in a two-year-old female with no past medical history. Initial vomiting and fast deterioration resulted in a sudden cardiac arrest. The postmortem examination found histological evidence of consistent, extensive lung damage. The absence of the characteristic symptoms made for some challenges when it came to diagnosis, showing precisely that in early life, you could well have many difficulties in catching PAVMs. This case highlights the need to take PAVMs into account as a potential cause of sudden death, particularly when there are no conspicuous symptoms. Awareness among forensic pathologists and consideration of genetic analysis for HHT in such cases is crucial for accurate diagnosis and management.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024489"},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trisomy 13 with unusual histological features typically described in Beckwith-Wiedemann Spectrum. 13 三体综合征，具有典型的贝克维茨-维德曼光谱（Beckwith-Wiedemann Spectrum）异常组织学特征。

Autopsy and Case Reports Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.486

Wilker Dias Martins, Elisa França Chaves, Flavia Cristina Gonçalves de Aquino, Sean Brasil de Oliveira, Isabela Dorneles Pasa, Bruno Guimarães Marcarini, Vitor Ribeiro Paes, Chong Ae Kim, Regina Schultz

{"title":"Trisomy 13 with unusual histological features typically described in Beckwith-Wiedemann Spectrum.","authors":"Wilker Dias Martins, Elisa França Chaves, Flavia Cristina Gonçalves de Aquino, Sean Brasil de Oliveira, Isabela Dorneles Pasa, Bruno Guimarães Marcarini, Vitor Ribeiro Paes, Chong Ae Kim, Regina Schultz","doi":"10.4322/acr.2024.486","DOIUrl":"10.4322/acr.2024.486","url":null,"abstract":"Trisomy 13, known as Patau syndrome, is a common aneuploidy with a well-known clinical phenotype. This case report describes a trisomy 13 patient with unusual autopsy findings, including features resembling the Beckwith-Wiedemann Spectrum. Due to abnormalities of gestational ultrasounds, a prenatal karyotype of amniotic fluid cells was performed, which resulted in 47, XY+13. Autopsy microscopy studies identified leptomeningeal glioneuronal heterotopia, which was not described as belonging to Patau syndrome. Other atypical findings were diffuse hyperplasia of pancreatic islets of Langerhans and adrenals enlargement with marked adrenocortical cytomegaly, characteristically seen in the Beckwith-Wiedemann Spectrum. Molecular genetic tests were not performed for the Beckwith-Wiedemann Spectrum. Still, due to the rarity of both disorders, this report may support the evidence that trisomy 13 can affect tissue organization and lead to unusual histopathologic features resembling classic overgrowth disorders.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024486"},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11104766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant hepatic hemangioma in a patient with cirrhosis: challenging to manage. 肝硬化患者的巨大肝血管瘤：处理难度大。

Autopsy and Case Reports Pub Date : 2024-04-04 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.485

Marlone Cunha-Silva, Clauber Teles Veiga, Larissa Bastos Eloy da Costa, Simone Reges Perales, Amanda Avesani Cavotto Furlan, Elaine Cristina de Ataíde, Ilka de Fátima Santana Ferreira Boin, Tiago Sevá-Pereira

{"title":"Giant hepatic hemangioma in a patient with cirrhosis: challenging to manage.","authors":"Marlone Cunha-Silva, Clauber Teles Veiga, Larissa Bastos Eloy da Costa, Simone Reges Perales, Amanda Avesani Cavotto Furlan, Elaine Cristina de Ataíde, Ilka de Fátima Santana Ferreira Boin, Tiago Sevá-Pereira","doi":"10.4322/acr.2024.485","DOIUrl":"https://doi.org/10.4322/acr.2024.485","url":null,"abstract":"Giant hepatic hemangiomas are occasional in patients with cirrhosis. It remains a challenge to decide on the need for treatment and choose the most appropriate intervention. A 62-year-old woman was recently diagnosed with cirrhosis and complained of upper abdominal fullness, reduction in oral food intake, and weight loss of 6 kg over the last three years. Upper digestive endoscopy evidenced thin-caliber esophageal varices and significant extrinsic compression of the lesser gastric curvature. Abdominal computed tomography revealed an exophytic tumor in the left hepatic lobe, measuring 11.5 cm, which had progressive centripetal contrast enhancement from the arterial phase, compatible with hepatic hemangioma. Serum tumor markers were negative, and her liver function was unimpaired. The patient underwent surgical resection (non-anatomical hepatectomy of segments II and III) which had no immediate complications, and the histopathological evaluation confirmed cavernous hepatic hemangioma. Two weeks later, she was admitted to the emergency room with jaundice, signs of hepatic encephalopathy, and moderate ascites, and was further diagnosed with secondary bacterial peritonitis. As no perforations, abscesses, or fistulas were observed on subsequent imaging tests, clinical management was successfully carried out. This case highlights that giant hepatic hemangiomas may be symptomatic and warrant treatment. In the setting of cirrhosis and portal hypertension, physicians should be aware of the risk of hepatic decompensation following surgical resection, even in patients with Child-Pugh class A.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024485"},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11021024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carnitine-acylcarnitine translocase deficiency: a case report with autopsy. 肉碱-酰肉碱转运酶缺乏症：一例尸检报告。

Autopsy and Case Reports Pub Date : 2024-04-04 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.483

Chennakeshava Thunga, Suvradeep Mitra, Devi Dayal, Sadhna Lal

引用次数: 0

Hyaline cartilage at the portal plate and gallbladder in biliary atresia. 胆道闭锁的门板和胆囊处的透明软骨。

Autopsy and Case Reports Pub Date : 2024-04-04 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.481

Sangamitra Rajasekaran, Hari Neupane, Monika Bawa, Uma Nahar Saikia, Sadhna Lal, Suvradeep Mitra

引用次数: 0