Autopsy and Case Reports最新文献_第10页

Oblivion: autopsy findings of a 31-year-old man with sudden cardiac arrest, a case report of a sequalae of Kawasaki disease. 遗忘:31岁男性心脏骤停的尸检结果，一例川崎病后遗症报告。

Autopsy and Case Reports Pub Date : 2022-10-19 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.404

Daniel Fernando Gallego, Maria Eugenia Zuluaga Ruiz, Desiree Ann Marshall

引用次数: 0

Complexities and complications of extreme obesity. 极度肥胖的复杂性和并发症。

Autopsy and Case Reports Pub Date : 2022-10-05 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.402

Haval Ali, Udit Naik, Michelle McDonald, Mohammad Almosa, Karen Horn, Alexis Staines, Louis Maximilian Buja

{"title":"Complexities and complications of extreme obesity.","authors":"Haval Ali, Udit Naik, Michelle McDonald, Mohammad Almosa, Karen Horn, Alexis Staines, Louis Maximilian Buja","doi":"10.4322/acr.2021.402","DOIUrl":"https://doi.org/10.4322/acr.2021.402","url":null,"abstract":"Obesity is a common chronic disorder and has detrimental long-term consequences if left untreated. Herein, we report a case of a young lady who suffered from morbid obesity and many of its consequences, and we present a literature review of these complications. While the cause of obesity is multifactorial, the genetic component is particularly important in the pathophysiology of marked obesity. Resistance to Leptin is considered one of the main causes of obesity. There is a unique relationship between polycystic ovary syndrome and obesity, as observed in our case. Obesity is associated with cardiovascular and lung diseases such as heart failure, thromboembolic disease, sleep apnea, and pulmonary hypertension. Our patient had cardiomegaly (730 gm) with eccentric hypertrophy of left and right ventricles. The coronary arteries and aorta were free of atherosclerosis, which is a surprising finding that relates to the mysterious phenomenon of obesity paradox. The terminal event in our young woman was multiple segmental and subsegmental pulmonary arterial thrombi/thromboemboli superimposed on chronic cardiopulmonary stress due to massive obesity.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021402"},"PeriodicalIF":0.0,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33514962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adult diffuse hepatic hemangiomatosis. 成人弥漫性肝血管瘤病。

Autopsy and Case Reports Pub Date : 2022-09-23 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.401

Neha Bhardwaj, Mayur Parkhi, Manish Kumar, Lileswar Kaman, Suvradeep Mitra

{"title":"Adult diffuse hepatic hemangiomatosis.","authors":"Neha Bhardwaj, Mayur Parkhi, Manish Kumar, Lileswar Kaman, Suvradeep Mitra","doi":"10.4322/acr.2021.401","DOIUrl":"https://doi.org/10.4322/acr.2021.401","url":null,"abstract":"Diffuse hepatic hemangiomatosis (DHH) is an uncommon vascular lesion, though hemangiomas are the commonest benign tumors of the liver. The etiology is largely unknown to date; however, its association with giant cavernous hemangiomas (GCH) has been reported in the literature. We present herein, the case of a 37-year-old hypothyroid woman with abdominal fullness for 2 months. The contrast-enhanced computed tomography revealed multiple well-encapsulated lesions involving the liver lobes and was diagnosed as giant cavernous hemangiomas. Most of them, except the deep-seated ones, were enucleated. Histopathological examination highlighted the presence of GCH with irregular margin, replacement of hepatic parenchyma, and presence of multiple micro-hemangiomas suggesting the possibility of DHH further substantiated by retrospective radiological assessment. No extrahepatic vascular lesion was noted, and the post-operative recovery and follow-up were uneventful. Adult DHH is an uncommon entity. The diagnosis of DHH and its distinction from GCH are important from the management and prognostic point of view as recurrence, extrahepatic manifestations, features of consumption coagulopathy, and death from the complications are not uncommon.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021401"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40389484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Renal lymphangiectasia. 肾淋巴管扩张。

Autopsy and Case Reports Pub Date : 2022-09-23 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.399

Sangamitra Rajasekaran, Mayur Parkhi, Ravi Kanojia, Aravind Sekar, Ritambhra Nada

引用次数: 3

Calcifying fibrous tumor. 钙化纤维性肿瘤。

Autopsy and Case Reports Pub Date : 2022-09-20 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.400

Hanan Elsarraj, Ameer Hamza

{"title":"Calcifying fibrous tumor.","authors":"Hanan Elsarraj, Ameer Hamza","doi":"10.4322/acr.2021.400","DOIUrl":"https://doi.org/10.4322/acr.2021.400","url":null,"abstract":"Calcifying fibrous tumor is a rare benign mesenchymal neoplasm. The etiology and pathogenesis of this tumor are uncertain. It has wide anatomical distribution. The tumor is most commonly found in the soft tissues of the extremities in younger individuals. However, in middle-aged patients, it tends to affect the visceral locations more commonly. In visceral location, it can mimic aggressive lesions clinically. The purpose of this report is to describe a case of calcifying fibrous tumor in a 71-year-old female with a history of breast carcinoma who was found to have an incidental small bowel mass on her follow-up. Clinically and radiologically, the mass was suspicious for either metastatic disease or gastrointestinal stromal tumor. The patient underwent open small bowel resection, and a 6.5 cm segment of the small bowel was sent to pathology. Grossly, a 2.0 cm tan-pink smooth round submucosal polyploid mass protruding into the lumen, mimicking a gastrointestinal stromal tumor, was identified. The tumor was hard and serially sectioned to reveal a white, calcified cut surface. Microscopically, the tumor appeared hypocellular and composed of scant spindle cells embedded in a dense, hyalinized and calcified collagenous stroma. Immunohistochemical stains for pan-cytokeratin, DOG1, desmin, S100, CD34, and MUC4 were negative, and a diagnosis of the calcifying fibrous tumor was rendered. This case provides a rare gross specimen image of calcifying fibrous tumor and highlights the importance of knowledge of rare entities in providing an accurate diagnosis for entities that can mimic other lesions.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021400"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40389485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benign glandular schwannoma. 良性腺神经鞘瘤。

Autopsy and Case Reports Pub Date : 2022-09-15 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.398

Khaldoon Aljerian

引用次数: 0

Suppurative minor salivary gland sialolithiasis. 化脓性小唾液腺涎石症。

Autopsy and Case Reports Pub Date : 2022-09-12 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.397

Camila de Oliveira Barbeiro, Roberto Henrique Barbeiro, Andreia Bufalino, Jorge Esquiche León

{"title":"Suppurative minor salivary gland sialolithiasis.","authors":"Camila de Oliveira Barbeiro, Roberto Henrique Barbeiro, Andreia Bufalino, Jorge Esquiche León","doi":"10.4322/acr.2021.397","DOIUrl":"https://doi.org/10.4322/acr.2021.397","url":null,"abstract":"Sialolithiasis is a common nonneoplastic disease of the major salivary glands that often affects the submandibular glands. Minor salivary gland involvement by sialolithiasis is uncommon, with only 273 cases reported. A long clinical history, acute symptoms, and mucopurulent discharge are unusual features of these cases. Herein, we report the case of a 63-year-old woman who complained of symptomatic nodular swelling of the buccal mucosa associated with purulent discharge for several days. The clinical history lasted 15 years, with episodes of asymptomatic non-suppurative swelling in the same area. The patient underwent surgical excision. The microscopic examination revealed chronic nonspecific sialadenitis associated with psammomatous calcifications, confirming minor salivary gland sialolithiasis. After 3 years of follow-up, the patient was free of symptoms. Patients with sialolithiasis are usually asymptomatic; however, swelling, pain, and fistula may be present in rare cases. The presence of purulent exudate should lead to the differential diagnosis of stomatitis glandularis, a rare inflammatory condition affecting the minor salivary glands. Sialolithiasis and stomatitis glandularis should be considered in the clinical differential diagnosis of symptomatic suppurative nodular swelling affecting the oral mucosa, and histopathological analysis is necessary for the diagnosis.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021397"},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33482791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Sudden death associated with lipoma of the cerebellopontine angle. 猝死与脑桥小脑角脂肪瘤有关。

Autopsy and Case Reports Pub Date : 2022-08-26 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.396

Stefano Tambuzzi, Guendalina Gentile, Michele Boracchi, Arnaldo Migliorini

引用次数: 0

Herpes simplex virus-1 triggered hemophagocytic lymphohistiocytosis in a patient with granulomatosis with polyangiitis. 单纯疱疹病毒-1引发肉芽肿合并多血管炎患者的噬血细胞性淋巴组织细胞增多症。

Autopsy and Case Reports Pub Date : 2022-08-17 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.395

Vanessa A States, Meghan E Kapp

引用次数: 1

Lymphoplasmacyte-rich meningioma with hematologic signs and PD-L1 over-expression. 淋巴浆细胞丰富的脑膜瘤伴血液学征象和PD-L1过表达。

Autopsy and Case Reports Pub Date : 2022-08-12 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.394

Gabriele Gaggero, Michela Campora, Davide Taietti, Giannamaria Cerruti, Enrico Lo Bue, Monica Truffelli, Marco Ceraudo, Pietro Fiaschi

{"title":"Lymphoplasmacyte-rich meningioma with hematologic signs and PD-L1 over-expression.","authors":"Gabriele Gaggero, Michela Campora, Davide Taietti, Giannamaria Cerruti, Enrico Lo Bue, Monica Truffelli, Marco Ceraudo, Pietro Fiaschi","doi":"10.4322/acr.2021.394","DOIUrl":"https://doi.org/10.4322/acr.2021.394","url":null,"abstract":"Lymphoplasmacyte-rich meningioma (LPRM) is one of the rarest variants of grade I meningiomas. It can be clinically associated with prominent peripheral blood abnormalities, anemia, and/or various gammopathy, which usually disappear after surgical removal of the tumor. We document a case of right frontal LPRM in a 72-year-old male who presented general cognitive decadence. The patient suffered from mild anemia. The LPRM is a rare variant of meningioma, with only a few cases globally reported in the literature. It has been categorized as a grade I tumor in the 2021 World Health Organization (WHO) classification central nervous system. Due to the rarity, this meningioma variant origin and biological behavior are still not clear. Immunohistochemistry profile showed prominent PD-L1 expression, leading to additional interrogation on LPRM immunomorphological characteristics, the significance of the inflammatory tumoral microenvironment and its correlation with the immune-checkpoints.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021394"},"PeriodicalIF":0.0,"publicationDate":"2022-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9390789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40718845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1