Autopsy and Case Reports最新文献

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ERRATUM: Hydatid cyst involving the mandible ramus. ERRATUM:累及下颌支的棘球蚴囊肿。
Autopsy and Case Reports Pub Date : 2023-07-19 eCollection Date: 2023-01-01 DOI: 10.4322/acr.2023.441
{"title":"ERRATUM: Hydatid cyst involving the mandible ramus.","authors":"","doi":"10.4322/acr.2023.441","DOIUrl":"10.4322/acr.2023.441","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.4322/acr.2023.437.].</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"13 ","pages":"e2023441"},"PeriodicalIF":0.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41175114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Xanthogranulomatous Endometritis with calculus formation in setting of prolapsed uterus. 子宫脱垂时伴有结石形成的黄色颗粒瘤性子宫内膜炎。
Autopsy and Case Reports Pub Date : 2023-07-19 eCollection Date: 2023-01-01 DOI: 10.4322/acr.2023.439
Nikhil Kumar, Prima Shuchita Lakra, Ranwir Kumar Sinha, Asitava Deb Roy, Debarshi Saha, Jitendra Kumar Sinha
{"title":"Xanthogranulomatous Endometritis with calculus formation in setting of prolapsed uterus.","authors":"Nikhil Kumar,&nbsp;Prima Shuchita Lakra,&nbsp;Ranwir Kumar Sinha,&nbsp;Asitava Deb Roy,&nbsp;Debarshi Saha,&nbsp;Jitendra Kumar Sinha","doi":"10.4322/acr.2023.439","DOIUrl":"https://doi.org/10.4322/acr.2023.439","url":null,"abstract":"<p><p>Xanthogranulomatous inflammation is a rare benign inflammatory lesion characterized by sheets of lipid-laden foamy histiocytes. It has been reported in various organs, mainly the kidney and gall bladder. Xanthogranulomatous endometritis (XGE) is sporadic, with only a few cases reported in the English medical literature. Herein, we report a case of xanthogranulomatous endometritis with the formation of stones in a 50-year-old female patient with a prolapsed uterus. Grossly the endometrium was irregular, and the uterine cavity was filled with a yellow friable material, a polypoid growth, and yellowish stones. The microscopy showed sheets of histiocytes with few preserved endometrial glands. In this case, the xanthogranulomatous inflammation may mimic a clear cell carcinoma involving the endometrium and myometrium. One of the important differential diagnoses is malakoplakia. Immunohistochemistry and special stains are helpful in diagnosis.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"13 ","pages":"e2023439"},"PeriodicalIF":0.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41174727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal pulmonary thromboembolism associated with uterine carcinosarcoma. 与子宫癌肉瘤相关的致命肺血栓栓塞。
Autopsy and Case Reports Pub Date : 2023-07-13 eCollection Date: 2023-01-01 DOI: 10.4322/acr.2023.438
Giorgia Lodetti, Stefano Tambuzzi, Salvatore Andreola, Guendalina Gentile, Riccardo Zoja
{"title":"Fatal pulmonary thromboembolism associated with uterine carcinosarcoma.","authors":"Giorgia Lodetti,&nbsp;Stefano Tambuzzi,&nbsp;Salvatore Andreola,&nbsp;Guendalina Gentile,&nbsp;Riccardo Zoja","doi":"10.4322/acr.2023.438","DOIUrl":"https://doi.org/10.4322/acr.2023.438","url":null,"abstract":"Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 1 University of Milan, Department of Biomedical Sciences for Health, Laboratory of Forensic Histopathology and Microbiology Section of Forensic and Insurance Medicine, Milan, Italy Fatal pulmonary thromboembolism associated with uterine carcinosarcoma","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"13 ","pages":"e2023438"},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41172661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated Nasal subtype Extranodal NK/T-cell lymphoma and its diagnostic difficulties in antemortem biopsies 弥散性鼻亚型结外NK/ t细胞淋巴瘤及其生前活检诊断的困难
Autopsy and Case Reports Pub Date : 2023-01-01 DOI: 10.4322/acr.2023.445
Aravind Sekar, Siddharth Jain, Jaimanti Bakshi, Suneel Rachagiri, Harish Bhujade, Rajender Kumar, Amanjit Bal
{"title":"Disseminated Nasal subtype Extranodal NK/T-cell lymphoma and its diagnostic difficulties in antemortem biopsies","authors":"Aravind Sekar, Siddharth Jain, Jaimanti Bakshi, Suneel Rachagiri, Harish Bhujade, Rajender Kumar, Amanjit Bal","doi":"10.4322/acr.2023.445","DOIUrl":"https://doi.org/10.4322/acr.2023.445","url":null,"abstract":"ABSTRACT Extranodal NK/T- cell lymphoma (ENKTCL) is an aggressive lymphoma driven by Epstein-Barr virus (EBV) infection in genetically susceptible individuals. It was historically called a lethal midline granuloma. Due to the angio-destructive nature of ENKTCL, lymphoma cells are often accompanied and masked by necrosis and dense inflammation in the biopsy. Further, the biopsy may show vasculitis, which can mimic granulomatosis with polyangiitis. Due to these masquerades, ENKTCL is often misdiagnosed in the biopsy. Several biopsies may be required to establish the diagnosis. We describe the clinical course and autopsy findings of a young female who presented with a hard-palate ulcer. Antemortem biopsies failed to establish the diagnosis. The autopsy revealed an advanced nasal subtype of Extranodal NK/T-cell lymphoma with dissemination to the kidneys, adrenals, liver, spleen, and small intestine.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136002804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solitary fibrous tumor of the tongue. 舌头上的单发纤维瘤
Autopsy and Case Reports Pub Date : 2022-11-17 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.405
Juliana Mota Siqueira, Daniele Heguedusch, Emília Maria Gomes Aguiar, Anaeliza Figueiredo Dos Santos, Fabio Abreu Alves, Fabio Daumas Nunes
{"title":"Solitary fibrous tumor of the tongue.","authors":"Juliana Mota Siqueira, Daniele Heguedusch, Emília Maria Gomes Aguiar, Anaeliza Figueiredo Dos Santos, Fabio Abreu Alves, Fabio Daumas Nunes","doi":"10.4322/acr.2021.405","DOIUrl":"10.4322/acr.2021.405","url":null,"abstract":"<p><p>Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with a rare presentation in the oral cavity. Herein, we report a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination revealed a well-circumscribed mass covered by normal mucosa with a fibrous consistency. Due to non-specific clinical findings, the initial diagnostic hypotheses include benign submucosal neoplasms such as leiomyoma, neurofibroma, SFT, and others. An excisional biopsy was performed. Microscopically, the tumor was surrounded by a thick fibrous capsule; hypo and hypercellular areas were arranged in a storiform pattern with a stroma formed by collagen and abundant vascularization. Tumor cells showed immunopositivity for CD34 and STAT-6 and no expression of CD99, AML, S-100, and Ki-67. According to these findings, the diagnosis of SFT was established. After 24 months, the patient is asymptomatic and has no evidence of recurrence. Although oral involvement is rare, SFT should be included in the differential diagnosis of oral submucosal lesions.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021405"},"PeriodicalIF":0.0,"publicationDate":"2022-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40706827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adult-onset Still's disease after ChAdOx1 nCoV-19 vaccine: a possible association. ChAdOx1 nCoV-19疫苗后成人发病斯蒂尔斯病:可能的关联
Autopsy and Case Reports Pub Date : 2022-11-07 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.403
Laíssa Fiorotti Albertino, Isac Ribeiro Moulaz, Tammer Ferreira Zogheib, Martina Zanotti Carneiro Valentim, Ketty Lysie Libardi Lira Machado
{"title":"Adult-onset Still's disease after ChAdOx1 nCoV-19 vaccine: a possible association.","authors":"Laíssa Fiorotti Albertino,&nbsp;Isac Ribeiro Moulaz,&nbsp;Tammer Ferreira Zogheib,&nbsp;Martina Zanotti Carneiro Valentim,&nbsp;Ketty Lysie Libardi Lira Machado","doi":"10.4322/acr.2021.403","DOIUrl":"https://doi.org/10.4322/acr.2021.403","url":null,"abstract":"<p><p>With emergent Sars-Cov-2, a highly transmissive virus that caused millions of deaths worldwide, the development of vaccines became urgent to combat COVID-19. Although rare, important adverse effects had been described in a hypothetical scenario of immune system overstimulation or overreaction. Still's disease is a rare inflammatory syndrome of unknown etiology. It manifests as a cytokine storm, mainly IL-18 and IL-1β, and presents itself with fever spikes, joint pain, maculopapular evanescent salmon-pink skin rash, and sore throat, among other symptoms. Here, we report a case of a 44-year-old healthy male who developed adult-onset Still's disease (AOSD) with atypical symptoms after both doses of ChAdOx1 nCoV-19 vaccine with 3 months of dose interval. The medical team suspected Still's disease and started prednisone 1 mg/kg (40mg). The next day the patient showed a marked improvement in articular and chest pains and had no other fever episodes. Therefore, he was discharged to continue the treatment in outpatient care. On the six-month follow-up, the patient was free of complaints, and the progressive corticoid withdrawal plan was already finished.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021403"},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40706826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Metastasis of mucinous breast carcinoma to the lower alveolus as initial presentation: a diagnostic dilemma. 黏液性乳腺癌转移到下肺泡作为初始表现:诊断困境。
Autopsy and Case Reports Pub Date : 2022-11-03 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.407
Priyadarshini Guha, Zachariah Chowdhury
{"title":"Metastasis of mucinous breast carcinoma to the lower alveolus as initial presentation: a diagnostic dilemma.","authors":"Priyadarshini Guha,&nbsp;Zachariah Chowdhury","doi":"10.4322/acr.2021.407","DOIUrl":"https://doi.org/10.4322/acr.2021.407","url":null,"abstract":"<p><p>Metastases in the oral cavity are rare and comprise approximately 1% of all oral malignancies. They usually involve the jaws but may also be found in the soft tissues and salivary glands. Women's most common metastatic malignancies are from primary breast cancers. However, metastasis of mucinous breast carcinoma to the lower alveolus mimicking an aggressive primary malignancy as the initial presentation is exceptionally uncommon. We describe the case of a 66-year-old lady with an ulceroproliferative growth in the right lower alveolus. The lesion eroded the mandible and involved the adjacent soft tissues with no prior history of lesion anywhere else. The lesion clinically mimicked a squamous cell carcinoma and masqueraded as a salivary gland mucinous adenocarcinoma on histopathology. The possibility of a metastatic lesion from the breast rather than a primary of the alveolus was also entertained, aided by the immunohistochemical findings of positivity of the tumor cells for GATA3. A positron emission tomography (PET) scan was undertaken to ascertain the primary site. It detected a hypermetabolic lesion in the left breast, which biopsy revealed mucinous breast carcinoma on histopathological evaluation. Metastasis of breast mucinous carcinoma by the hematogenous route is extremely rare; very few cases have been reported. This case illustrates the diagnostic challenges such a lesion can pose to the surgeon and the pathologist. In the advent of such lesions being the initial clinical presentation, a vigilant clinicopathological and radiological assessment is essential to detect the primary.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021407"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40476453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Gastric undifferentiated carcinoma, INI1-negative. 胃未分化癌,ini1阴性。
Autopsy and Case Reports Pub Date : 2022-11-03 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.408
Gabriele Gaggero, Luca Carlin, Margherita Concardi, Marta Ingaliso, Davide Taietti
{"title":"Gastric undifferentiated carcinoma, INI1-negative.","authors":"Gabriele Gaggero,&nbsp;Luca Carlin,&nbsp;Margherita Concardi,&nbsp;Marta Ingaliso,&nbsp;Davide Taietti","doi":"10.4322/acr.2021.408","DOIUrl":"https://doi.org/10.4322/acr.2021.408","url":null,"abstract":"HMB-45). EBV, CD99, CD117, SALL4, and Glypican3 were also negative. Finally, the absence of expression of INI1 (Figure 1D) is noteworthy. From a strictly microscopic point of view, the features of the neoplastic cells suggest the differential diagnosis between a GUC, an EBV-associated carcinoma with lymphoid stroma, an aggressive lymphoma, a metastatic melanoma, a germ cell neoplasm, a PEComa, and a rhabdomyosarcoma (or other types of sarcomas with epithelioid/rhabdoid pattern). 1 Based on the overall immunomorphological data, which allows us to exclude the other aforementioned hypotheses, we make the final diagnosis of GUC with rhabdoid morphological aspects and, according to the literature, lack of immunophenotypic expression for INI1.","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021408"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40465618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The many faces of endometriosis. 子宫内膜异位症的许多方面。
Autopsy and Case Reports Pub Date : 2022-11-03 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.409
Marcelo Luis Pereira de Souza, Talita Porto da Costa, Nathanael Pinheiro de Freitas, Maiara Ferreira de Souza, Daniel Abensur Athanazio
{"title":"The many faces of endometriosis.","authors":"Marcelo Luis Pereira de Souza,&nbsp;Talita Porto da Costa,&nbsp;Nathanael Pinheiro de Freitas,&nbsp;Maiara Ferreira de Souza,&nbsp;Daniel Abensur Athanazio","doi":"10.4322/acr.2021.409","DOIUrl":"https://doi.org/10.4322/acr.2021.409","url":null,"abstract":"<p><p>Endometriosis is a common disease; however, unusual findings may cause diagnostic difficulties. We present herein three cases illustrating different morphological appearances of endometriosis: 1) endometriosis with atypical hyperplasia associated with bilateral ovarian carcinoma (mixed clear cell/endometrioid in the left ovary and endometrioid in the right ovary); 2) deep infiltrating endometriosis with intravascular spread, polypoid configuration in peritoneal surfaces, and involvement of a lymph node; and 3) decidualized endometriosis with prominent myxoid/mucinous change and multivacuolated (pseudoxanthoma) cells. Awareness of uncommon morphological manifestations of endometriosis is important to avoid improper consideration of malignancy.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021409"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40465619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Juxtaglomerular cell tumor: report of a case with unusual presentation. 肾小球旁细胞瘤:1例异常表现。
Autopsy and Case Reports Pub Date : 2022-10-21 eCollection Date: 2022-01-01 DOI: 10.4322/acr.2021.406
Priscilla Quach, Ameer Hamza
{"title":"Juxtaglomerular cell tumor: report of a case with unusual presentation.","authors":"Priscilla Quach,&nbsp;Ameer Hamza","doi":"10.4322/acr.2021.406","DOIUrl":"https://doi.org/10.4322/acr.2021.406","url":null,"abstract":"<p><p>Juxtaglomerular cell tumor is a benign, renin-secreting neoplasm. The tumor arises from the juxtaglomerular apparatus cells of the kidney. Because the tumor is hormonally active, patients usually suffer from hypokalemia, hyperaldosteronism, and hypertension. Herein, we describe a case of a 19-year-old Asian female with a somewhat unusual presentation. A 19-year-old Asian female presented with upper extremity weakness, numbness, and tingling. On physical examination, the only notable finding was hypertension. Extensive workup revealed elevated aldosterone level and plasma renin activity. CT scan of the abdomen revealed a 2.2 cm mass in the lower pole of the left kidney. The mass was resected by partial nephrectomy. On microscopic evaluation, the tumor had glomoid appearance with sheets of uniform, round to polygonal cells with clear to eosinophilic cytoplasm. Immunohistochemical stains showed the tumor cells to be positive for CD117, CD34 and CD10 and negative for ER, PR, CK7, PAX-8, pan-cytokeratin, EMA, S100, Melan-A, HMB45, SMA and CAIX. Diagnosis of Juxtaglomerular cell tumor was rendered. This case highlights the importance of a regular physical exam and a high index of suspicion in patients presenting with unusual complaints.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":" ","pages":"e2021406"},"PeriodicalIF":0.0,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40435468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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