Autopsy and Case Reports最新文献

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Submandibular and sublingual salivary gland involvement in adenoid cystic carcinoma. 腺样囊性癌的颌下腺和舌下腺唾液腺受累。
Autopsy and Case Reports Pub Date : 2024-07-02 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.500
Poonam Ramnath Sawant, Manjeeta Mahesh Sinai Dhume, Anita Spadigam, Anita Dhupar
{"title":"Submandibular and sublingual salivary gland involvement in adenoid cystic carcinoma.","authors":"Poonam Ramnath Sawant, Manjeeta Mahesh Sinai Dhume, Anita Spadigam, Anita Dhupar","doi":"10.4322/acr.2024.500","DOIUrl":"10.4322/acr.2024.500","url":null,"abstract":"<p><p>Adenoid cystic carcinoma (AdCC) is a malignant salivary gland neoplasm that presents as an indolent but aggressive neoplasm. AdCC histogenesis is linked to the intercalated ducts of the salivary glands, equally affecting the major and minor glands. AdCC is associated with distant metastasis, most commonly to the lungs, and a high recurrence rate. AdCC accounts for 4.2% of all tumors. About 55% of all reported cases affect the submandibular gland, and around 50% of AdCC cases occur in the minor salivary glands. The present review describes a case of AdCC which presented a single nodular swelling on the right side involving the floor of the mouth. It also consolidates the histopathological profile of a case of AdCC with all the relevant histopathological features.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024500"},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant intrapulmonary solitary fibrous tumor. 肺内巨大单发纤维瘤
Autopsy and Case Reports Pub Date : 2024-06-21 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.494
Sheela Devi Chandakavadi Shivalingaiah, Deepika Gurumurthy, Gauri Dadich
{"title":"Giant intrapulmonary solitary fibrous tumor.","authors":"Sheela Devi Chandakavadi Shivalingaiah, Deepika Gurumurthy, Gauri Dadich","doi":"10.4322/acr.2024.494","DOIUrl":"10.4322/acr.2024.494","url":null,"abstract":"<p><p>Solitary fibrous tumor (SFT) is a soft tissue tumor of mesenchymal origin involving, most commonly, the pleura. Intrapulmonary SFT is a slow-growing tumor that rarely reaches giant forms. SFTs are asymptomatic and often randomly discovered by routine chest X-rays. The diagnosis requires histopathological and immunohistochemical (IHC) examinations. Most of the SFTs are benign and present an indolent course. Larger tumors are more likely to be malignant and consequently associated with a worse prognosis. Despite having histopathological criteria for malignancy, the behavior of SFTs is challenging to predict. We report a case of giant intrapulmonary SFT of intermediate risk.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024494"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidental finding of cardiac hydatid cyst during autopsy. 尸检时意外发现心脏水瘤囊肿。
Autopsy and Case Reports Pub Date : 2024-06-21 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.501
Nishant Purbey, Amit Patil, Shreekant Bharti, Keshav Chandra, Shashank Ranjan
{"title":"Incidental finding of cardiac hydatid cyst during autopsy.","authors":"Nishant Purbey, Amit Patil, Shreekant Bharti, Keshav Chandra, Shashank Ranjan","doi":"10.4322/acr.2024.501","DOIUrl":"10.4322/acr.2024.501","url":null,"abstract":"<p><p>Hydatidosis or echinococcosis is an endemic parasitic disease caused by the ingestion of eggs of echinococcal species worldwide. In India, the annual incidence varies from 1 to 200 per one 100,000 hab., with the highest prevalence reported in the Indian states of Andhra Pradesh and Tamil Nadu. The dog is the definitive host, while humans, sheep, and cattle are intermediate hosts. The disease usually involves the liver and lungs, with the kidney and other organs rare involvement. Cardiac hydatidosis is still further rare, seen in 0.2% to 2% of the patients who remain asymptomatic until the development of its complications. Sudden deaths in cardiac echinococcosis are mostly attributed to cardiac arrhythmias, coronary artery diseases, valvular diseases, cardiomyopathies, pericarditis, and cardiac tamponade. We, herein, report a rare case of cardiac hydatid cyst incidentally found during the autopsy of a 26-year-old male who died due to electrical injuries. A single greyish-white cystic mass measuring 1.5cm X 1.2cm was detected on the left anterior ventricular wall 4 cm above the apex and was confirmed microscopically as a hydatid cyst. The cause of death was attributed to external injury.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024501"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Localized cystic kidney disease: a case report unveiling clinical and histopathological challenges. 局部囊性肾病:揭示临床和组织病理学难题的病例报告。
Autopsy and Case Reports Pub Date : 2024-06-21 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.498
Teresita Mendez, Hisham F Bahmad, Francesca Polit, Nicole Carpio, Arman Gill, William F Burke, Akshay Bhandari, Robert Poppiti, Yumna Omarzai
{"title":"Localized cystic kidney disease: a case report unveiling clinical and histopathological challenges.","authors":"Teresita Mendez, Hisham F Bahmad, Francesca Polit, Nicole Carpio, Arman Gill, William F Burke, Akshay Bhandari, Robert Poppiti, Yumna Omarzai","doi":"10.4322/acr.2024.498","DOIUrl":"10.4322/acr.2024.498","url":null,"abstract":"<p><p>Localized cystic kidney disease (LCKD) is a distinct renal disorder characterized by the presence of cysts within specific regions of the kidneys. We present a rare case of a 41-year-old African American man, who presented to our medical center with lower urinary tract symptoms and gross hematuria. The initial assessment culminated in the identification of an uncomplicated urinary tract infection, prompting the prescription of appropriate oral antibiotic therapy. On follow-up after 5 months, the patient presented with gross hematuria. Imaging studies revealed a mixed-density cystic lesion of 2.6 cm situated within the interpolar region of the right kidney. This cystic lesion exhibited intricate septations at the superior pole of the kidney. Robotic-assisted right partial nephrectomy was performed, and pathologic examination was diagnostic for LCKD. This report not only underscores the uniqueness of LCKD but also presents a comprehensive review of the existing literature that pertains to this condition. Particular emphasis is placed upon its inherent benign behavior and its marked divergence from the progressive trajectory commonly associated with other renal diseases. We also explored the incidental findings of the disease, its diverse clinical symptomatology, conceivable etiological underpinnings, and the array of diagnostic modalities used. Finally, similarities in histopathologic findings with polycystic kidney disease and other entities are discussed, underscoring the importance of accurate diagnosis and management.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024498"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clear cell myomelanocytic tumor of ligamentum teres. 韧带透明细胞髓细胞瘤
Autopsy and Case Reports Pub Date : 2024-06-21 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.503
Ariba Zaidi, Debajyoti Chatterjee, Venu Bhargav, Vikas Gupta, Ashim Das
{"title":"Clear cell myomelanocytic tumor of ligamentum teres.","authors":"Ariba Zaidi, Debajyoti Chatterjee, Venu Bhargav, Vikas Gupta, Ashim Das","doi":"10.4322/acr.2024.503","DOIUrl":"10.4322/acr.2024.503","url":null,"abstract":"<p><p>Clear cell myomelanocytic tumor (CCMMT) of the falciform ligament/ligamentum teres is a rare hepatic tumor, a variant of the perivascular epithelioid cell tumor (PEComa) family. CCMMT is the rarest variant of hepatic PEComas. Only a few cases of CCMMT have been reported in the English literature. Because of its rarity, less is known about its biological behavior. We present a case of a 31-year-old female who complained of abdominal pain, bilious vomiting, and abdominal fullness over two months. The radiological impression was of focal nodular hyperplasia. The histological examination of the resection specimen revealed a well-circumscribed tumor arranged in fascicles, sheets, and a whorling pattern. The tumor cells were spindle to epithelioid shaped with abundant clear to pale eosinophilic cytoplasm. The tumor cells expressed both myoid (smooth muscle actin) and melanocytic (MelanA and HMB45) markers, while they were negative for hepatocytic and vascular markers. Thus, based on histology and immunohistochemistry, a diagnosis of CCMMT was made. This case presents the diagnostic challenges of CCMMT and discusses the differential diagnosis with a literature review.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024503"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of Sporadic Creutzfeldt-Jakob disease at a remote mountain hospital in the Indian Himalayan Region. 印度喜马拉雅地区一家偏远山区医院的一例罕见零星克雅二氏症病例。
Autopsy and Case Reports Pub Date : 2024-06-21 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.502
Nitu Sharma, Jitender Kumar Sharma, Ashima Chander, Khushdeep Shergill, Meghna Yadav
{"title":"A rare case of Sporadic Creutzfeldt-Jakob disease at a remote mountain hospital in the Indian Himalayan Region.","authors":"Nitu Sharma, Jitender Kumar Sharma, Ashima Chander, Khushdeep Shergill, Meghna Yadav","doi":"10.4322/acr.2024.502","DOIUrl":"10.4322/acr.2024.502","url":null,"abstract":"<p><p>Sporadic Creutzfeldt-Jakob disease (CJD) is a rare neurodegenerative spongiform encephalopathy that causes neuronal derangement secondary to prion protein. Its initial diagnosis is often complex and challenging due to non-specific clinical presentation, lack of awareness, and low clinical suspicion. This disease is invariably fatal, and most patients die within 12 months of presentation. Definite diagnosis of prion disease requires neuropathological analysis, usually done at autopsy. Here, we present the autopsy findings of a 57-year-old male patient, illustrating the complexity of diagnosing this disease early in the clinical course and the need for a broad differential diagnosis at the onset.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024502"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging infection: streptococcal toxic shock-like syndrome caused by group B Streptococcus (GBS), Streptococcus agalactiae. 新发感染:由 B 群链球菌(GBS)、无乳链球菌引起的链球菌中毒性休克样综合征。
Autopsy and Case Reports Pub Date : 2024-06-21 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.497
Fareed Rajack, Shawn Medford, Ali Ramadan, Tammey Naab
{"title":"Emerging infection: streptococcal toxic shock-like syndrome caused by group B Streptococcus (GBS), <i>Streptococcus agalactiae</i>.","authors":"Fareed Rajack, Shawn Medford, Ali Ramadan, Tammey Naab","doi":"10.4322/acr.2024.497","DOIUrl":"10.4322/acr.2024.497","url":null,"abstract":"<p><p><i>Streptococcus agalactiae</i> or Group B <i>Streptococcus</i> (GBS) infections are commonly associated with infections in neonates and pregnant women. However, there has been a rising incidence in nonpregnant adults. The risk of GBS infection in nonpregnant adults is increased for patients of advanced age and those with underlying medical conditions such as diabetes mellitus and cancer. We present a 77-year-old female with type-2 diabetes mellitus, hypertension, and bilateral foot ulcers that presented in probable septic shock with necrotic foot ulcers and necrotizing fasciitis and underwent bilateral lower limb amputations. The patient fulfilled the Streptococcal Toxic Shock Syndrome (STSS) criteria as defined by The Working Group on Severe Streptococcal Infections. These criteria were created for group A Streptococcus (<i>Streptococcus pyogenes</i>). Our patient fulfilled the Working Group's criteria, except that the blood culture was positive for group B Streptococcus (<i>Streptococcus agalactiae</i>). Numerous studies demonstrate the importance of early detection and antibiotic treatment for GBS infections in general and early surgical management for necrotizing soft tissue infections (NSTIs) such as necrotizing fasciitis.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024497"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal asphyxia due to large laryngeal granuloma. 巨大喉肉芽肿导致致命窒息。
Autopsy and Case Reports Pub Date : 2024-06-14 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.496
Ajay Kumar, Ravi Rautji, Asit Ranjan Mridha, Chittaranjan Behera
{"title":"Fatal asphyxia due to large laryngeal granuloma.","authors":"Ajay Kumar, Ravi Rautji, Asit Ranjan Mridha, Chittaranjan Behera","doi":"10.4322/acr.2024.496","DOIUrl":"10.4322/acr.2024.496","url":null,"abstract":"<p><p>Laryngeal granuloma, vocal process granuloma, or post-intubation granuloma are benign, inflammatory lesions of the arytenoid cartilage vocal process. The etiology of laryngeal granulomas is multifactorial, such as chronic irritation due to endotracheal intubation, vocal cord injury or trauma, and gastroesophageal reflux disease. They can arise postoperatively after mucosal injury due to orotracheal intubation. Clinical manifestations include voice change and dyspnea, which may start one to four months after extubation and may rarely lead to asphyxia. We presented a case of death due to glottic granuloma occurring after a surgical procedure to remove a laryngeal polyp attributed to previous laryngeal injuries by multiple intubations.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024496"},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A great simulator in clinical practice: mononeuritis multiplex in HIV infection. 临床实践中的绝佳模拟器:HIV 感染中的多发性单神经炎。
Autopsy and Case Reports Pub Date : 2024-06-14 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.493
José Pedro Soares Baima, Beatriz Carneiro Gondim Silva, Vanessa Lopes Vieira, Luiz Pedro Meireles, Milton Hideaki Arai, Angelina Maria Martins Lino
{"title":"A great simulator in clinical practice: mononeuritis multiplex in HIV infection.","authors":"José Pedro Soares Baima, Beatriz Carneiro Gondim Silva, Vanessa Lopes Vieira, Luiz Pedro Meireles, Milton Hideaki Arai, Angelina Maria Martins Lino","doi":"10.4322/acr.2024.493","DOIUrl":"10.4322/acr.2024.493","url":null,"abstract":"<p><p>HIV infection is a chameleon, mimicking several diseases. Herein, we report a previously healthy 39-year-old woman who, over 2 months, developed arthritis, weight loss, and confluent multiple mononeuropathy. Extensive laboratory investigation showed positive serology for HIV, with a CD4 count of 100 cells, and necrotizing vasculitis on a nerve biopsy not associated with CMV co-infection, allowing the diagnosis of polyarteritis nodosa-like vasculitis in an HIV-infected patient. Apart from the infection, HIV-related autoimmunity can affect any organ and contribute to the complexity of the clinical presentation of HIV infection.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024493"},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leiomyoma of maxillary sinus. 上颌窦雷肌瘤
Autopsy and Case Reports Pub Date : 2024-06-13 eCollection Date: 2024-01-01 DOI: 10.4322/acr.2024.495
Ravi Hari Phulware, Shalini Jain, Akash Dhiman, Arvind Ahuja, Arvind Kumar
{"title":"Leiomyoma of maxillary sinus.","authors":"Ravi Hari Phulware, Shalini Jain, Akash Dhiman, Arvind Ahuja, Arvind Kumar","doi":"10.4322/acr.2024.495","DOIUrl":"https://doi.org/10.4322/acr.2024.495","url":null,"abstract":"","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024495"},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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