José Pedro Soares Baima, Beatriz Carneiro Gondim Silva, Vanessa Lopes Vieira, Luiz Pedro Meireles, Milton Hideaki Arai, Angelina Maria Martins Lino
{"title":"临床实践中的绝佳模拟器:HIV 感染中的多发性单神经炎。","authors":"José Pedro Soares Baima, Beatriz Carneiro Gondim Silva, Vanessa Lopes Vieira, Luiz Pedro Meireles, Milton Hideaki Arai, Angelina Maria Martins Lino","doi":"10.4322/acr.2024.493","DOIUrl":null,"url":null,"abstract":"<p><p>HIV infection is a chameleon, mimicking several diseases. Herein, we report a previously healthy 39-year-old woman who, over 2 months, developed arthritis, weight loss, and confluent multiple mononeuropathy. Extensive laboratory investigation showed positive serology for HIV, with a CD4 count of 100 cells, and necrotizing vasculitis on a nerve biopsy not associated with CMV co-infection, allowing the diagnosis of polyarteritis nodosa-like vasculitis in an HIV-infected patient. Apart from the infection, HIV-related autoimmunity can affect any organ and contribute to the complexity of the clinical presentation of HIV infection.</p>","PeriodicalId":53117,"journal":{"name":"Autopsy and Case Reports","volume":"14 ","pages":"e2024493"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253905/pdf/","citationCount":"0","resultStr":"{\"title\":\"A great simulator in clinical practice: mononeuritis multiplex in HIV infection.\",\"authors\":\"José Pedro Soares Baima, Beatriz Carneiro Gondim Silva, Vanessa Lopes Vieira, Luiz Pedro Meireles, Milton Hideaki Arai, Angelina Maria Martins Lino\",\"doi\":\"10.4322/acr.2024.493\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>HIV infection is a chameleon, mimicking several diseases. Herein, we report a previously healthy 39-year-old woman who, over 2 months, developed arthritis, weight loss, and confluent multiple mononeuropathy. Extensive laboratory investigation showed positive serology for HIV, with a CD4 count of 100 cells, and necrotizing vasculitis on a nerve biopsy not associated with CMV co-infection, allowing the diagnosis of polyarteritis nodosa-like vasculitis in an HIV-infected patient. Apart from the infection, HIV-related autoimmunity can affect any organ and contribute to the complexity of the clinical presentation of HIV infection.</p>\",\"PeriodicalId\":53117,\"journal\":{\"name\":\"Autopsy and Case Reports\",\"volume\":\"14 \",\"pages\":\"e2024493\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253905/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Autopsy and Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4322/acr.2024.493\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Autopsy and Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4322/acr.2024.493","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
A great simulator in clinical practice: mononeuritis multiplex in HIV infection.
HIV infection is a chameleon, mimicking several diseases. Herein, we report a previously healthy 39-year-old woman who, over 2 months, developed arthritis, weight loss, and confluent multiple mononeuropathy. Extensive laboratory investigation showed positive serology for HIV, with a CD4 count of 100 cells, and necrotizing vasculitis on a nerve biopsy not associated with CMV co-infection, allowing the diagnosis of polyarteritis nodosa-like vasculitis in an HIV-infected patient. Apart from the infection, HIV-related autoimmunity can affect any organ and contribute to the complexity of the clinical presentation of HIV infection.