Journal of Oral and Maxillofacial Pathology最新文献

{"title":"Assessment of lip and finger print patterns in patients with type 2 diabetes mellitus and dental caries: A cross-sectional study.","authors":"Dakshayani Vijay Patil, Jiji George, Ankita Singh, Puneet Ahuja","doi":"10.4103/jomfp.jomfp_78_24","DOIUrl":"10.4103/jomfp.jomfp_78_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>Globally, the prevalence of diabetes and dental caries has been soaring high in recent times. There is a constant effort in the scientific community to develop a reliable and economic early predictor which can serve the purpose of mass screening of genetically vulnerable populations. The present study attempts to evaluate the different types of lip prints and finger prints in diabetes mellitus and dental caries and to see association between the most common diseases (diabetes mellitus and dental caries) if any.</p><p><strong>Materials and methods: </strong>Study subjects included 100 subjects (50 uncontrolled Type II diabetes mellitus patients and 50 healthy controls) in the age group of 30-80 years among the population of Lucknow. Lip prints were obtained using lipstick and cellophane paper, analysed, and classified using Suzuki and Tsuchihashi's classification. Finger prints were obtained using inkpad, analysed, and classified using Henry's system of classification.</p><p><strong>Results: </strong>We found loop-type fingerprints and type IV lip prints associated with diabetic patients. Non-diabetics showed loop-type fingerprints and type I lip prints. We found increased dental caries incidence (DMFT scores) in diabetics. Diabetic subjects with caries showed loop fingerprints, which reiterated our earlier findings but are not associated with type IV lip prints. Non-diabetics with caries showed arch fingerprints, but they are not associated with type I lip prints. We found that DMFT scores that we used to assess caries did not associate well with lip prints.</p><p><strong>Conclusion: </strong>The results from our study strongly suggest that dermatoglyphics can be used as a non-invasive technique to mass screen for diabetes as well as dental caries as both diseases are predominantly associated with loop-type fingerprints. Type IV lip prints could be used to screen for diabetes, but no association of lip prints was seen in patients with caries.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"409-414"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Focal osteoporotic bone marrow defect: A happenstance finding.","authors":"Shalini Nair, Shahnaz Mahaboob, Jobin Mathew, Aiswarya Thoyakkat","doi":"10.4103/jomfp.jomfp_22_24","DOIUrl":"10.4103/jomfp.jomfp_22_24","url":null,"abstract":"<p><p>Focal osteoporotic bone marrow defects (FOBMDs) of jaws are rare and usually discovered as an incidental radiographic finding. They present as a poorly demarcated radiolucency affecting the posterior mandible of middle-aged women with pathogenesis remaining unknown. A 60-year-old female patient had visited our dental college for routine dental checkup and oral prophylaxis. Her radiograph revealed a well-defined radiolucency in the left mandibular posterior region as an incidental finding. Clinical examination revealed a diffuse swelling in the above-mentioned region which the patient had not noticed. The patient gave a history of trauma in the same region almost 20 years back. Incisional biopsy was performed. Microscopic examination revealed multiple bits of fatty fibro cellular tissue resembling the bone marrow with aggregates of blood cells. A diagnosis of FOBMD was given. FOBMD, although rare, should be included in differential diagnosis of the radiolucent lesions of the jaws.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"511-514"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hand, foot and mouth disease (HFMD): A case report.","authors":"Hema Suryawanshi, Manisha Sahu, Priyambada Singh","doi":"10.4103/jomfp.jomfp_527_23","DOIUrl":"10.4103/jomfp.jomfp_527_23","url":null,"abstract":"<p><p>Hand, foot and mouth disease (HFMD) is a viral highly contagious disease affecting mostly infants and children and occasionally adults. It has become a significant public health problem because of frequent outbreaks and rise in its incidence, severity and fatal complications in Southeast Asian countries in the last few decades. India had experienced a sudden resurgence of HFMD recently in the year 2022. The clinical course of HFMD is mainly mild and self-limiting with recovery within 1-2 weeks, but in few patient's, severe form of infection has been reported. In this report, we present the case of a 4-year-old boy presenting with HFMD.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"464-466"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathophysiology of oral lesions subsequent to SARS-CoV-2 vaccination: A systematic review.","authors":"Preeti Sharma, Sangeeta Malik, Vijay Wadhwan, Rishabh Sharma","doi":"10.4103/jomfp.jomfp_511_23","DOIUrl":"10.4103/jomfp.jomfp_511_23","url":null,"abstract":"<p><p>Amidst worldwide reports of adverse oral lesions subsequent to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination, the current systematic review planned to determine the prevalence of adverse oral events in adult individuals (≥18 years) after SARS-CoV-2 vaccination, emphasizing upon the type and dose of vaccine, time of onset, and underlying pathophysiology. The registered protocol (PROSPERO CRD42023421307), conforming with PRISMA guidelines, included an all-inclusive literature search through online databases, consisting of Scopus, PubMed/MEDLINE, Web of Science, Lilacs, Livivo, and PROSPERO, completed on 2 May 2023, followed by assessment of risk of bias by Joana Briggs Institute Evaluation Checklist. Due to the paucity of literature, case reports and case series were included. Self-reported lesions were excluded. Qualitative synthesis employing Microsoft Excel software 2019 revealed low prevalence (43 subjects) from 26 case reports and two case series. There were multiple erosive oral ulcers on gingiva, palate, burning pain in the mouth, xerostomia, tongue fissuring and glossitis, palatal petechiae, diffuse erythematous lesions and loss of smell (16.2%), primary herpetic gingivostomatitis (21%), oral lichen planus (16.2%), Stevens-Johnson syndrome (6.9%), Bell's palsy in four cases where two cases were Guillain-Barré syndrome (9.3%), erythema multiforme (11.6%), pemphigus (4.6%), idiopathic thrombocytopenic purpura (6.9%), unilateral hypoglossal nerve palsy (4.6%), and trigeminal neuralgia (2.3%). Maximum cases (22 subjects) presented oral lesions after Pfizer (BNT162b2) SARS-CoV-2 vaccine. No association was found between the vaccine type and dose with oral side effects. Dentists must be aware of the oral adverse effects after coronavirus disease 2019 vaccination to better understand the pathogenesis and the risk factors associated with such reactions.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"443-454"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer stem cells targeted therapy: A changing concept in head and neck squamous cell carcinoma.","authors":"Adesh S Manchanda, Harmandeep K Rai, Manvir Kaur, Paras Arora","doi":"10.4103/jomfp.jomfp_248_24","DOIUrl":"10.4103/jomfp.jomfp_248_24","url":null,"abstract":"<p><p>Identification of cancer stem cells (CSCs), their multilineage potential, and their ability of self-renewal have revolutionised the current concepts of cancer treatment. The suspected role of CSCs in cancer initiation, progression and relapse with the observed resistance to conventional cancer treatments has led to the development of more specific and targeted therapies. Identification of the properties of stem cells (SCs) and their potential for localisation in cancer has made targeted anti-cancer treatment possible by incorporating some modifications into these SCs. The same concept has been applied to the treatment strategy for head and neck squamous cell carcinoma (HNSCC) to control the relapse and improve the mortality rates in patients. This review aims to discuss the role of CSCs in the course and relapse of HNSCC, various surface markers for their identification and SC-targeted therapy options for the treatment of HNSCC, with a highlight on the advantages, shortcomings, opportunities and challenges to SC therapy in head and neck squamous cell carcinoma, treatment and scope for future research.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"455-463"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative correlation of serum and salivary trace elements in oral squamous cell carcinoma and oral potentially malignant disorders: An institution-based biochemical analysis.","authors":"Fahad M Samadi, N Sivakumar, Manjari Sonam, Pooja Sharma, Shaista Suhail, Mohammad Kaleem Ahmad","doi":"10.4103/jomfp.jomfp_34_24","DOIUrl":"10.4103/jomfp.jomfp_34_24","url":null,"abstract":"<p><strong>Background: </strong>Trace elements are the important components that play a crucial role in various functions of the human body at cellular and molecular levels. Considering the role of the trace elements in precancerous and cancerous conditions, estimation of their levels in these conditions could aid in understanding the disease process and progression. The purpose of this study is to determine the alteration in salivary electrolyte concentration of oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC) patients to correlate the variations with the severity and biological behaviour.</p><p><strong>Material and method: </strong>A total of 70 subjects were included in this study, and they were divided into three groups: patients with OSCC (30), OPMDs (30) and apparently healthy individuals (10). An informed consent was obtained, following which blood and saliva samples were collected from the participants. Salivary and serum levels of copper, zinc, lead, cadmium, calcium and magnesium were measured and compared between the groups.</p><p><strong>Results: </strong>The levels of biochemical elements in both serum and saliva were in perfect correlation. The amount of all the estimated metallic ions was found to be significantly (<i>P</i> 0.001) increased in OSCC followed by OPMDs and normal mucosa. The levels of copper, cadmium and magnesium were gradually increased in increasing grades of OSCC (<i>P</i> 0.001).</p><p><strong>Conclusion: </strong>Salivary trace element levels could possibly have diagnostic significance in the early evaluation of OPMDs and OSCC as well. Increased levels of these elements might be used as a marker of disease progression and predictor of prognosis.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"434-442"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A brief insight regarding Nasopalatine duct cyst- Report of two cases with a review of literature.","authors":"Snehanjan Sarangi, Debarati Ray, Tathagata Bhattacharjee, Jay Gopal Ray","doi":"10.4103/jomfp.jomfp_3_24","DOIUrl":"10.4103/jomfp.jomfp_3_24","url":null,"abstract":"<p><p>Nasopalatine duct cysts (NPDCs) are among the most common nonodontogenic cysts, typically located in the midline of anterior maxillary hard palate. They usually arise from the embryonic epithelial vestiges of the nasopalatine duct. NPDCs predominantly affect adult males, generally during their fourth decade of life. Clinically, they present as asymptomatic or occasionally painful, fluctuant or discharging swellings involving the hard palate. Radiographically, NPDCs are characterized by a well-defined, fairly corticated, inverted pear-shaped or heart-shaped radiolucency situated between the roots of the maxillary incisors. Histopathologically, NPDCs exhibit a wide spectrum of findings. The lining may be comprised of stratified squamous, pseudostratified ciliated columnar, columnar, or cuboidal epithelium, or a combination and transition of these types. The cystic capsule is fibrocollagenous and can exhibit certain unique features, such as neurovascular bundles, mucous glands, and cartilaginous rests. NPDCs are typically managed through surgical enucleation, and recurrences are rare. Herein, we present two cases of NPDCs, along with a brief overview of their origin, relevant diagnostic features, and management.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"483-487"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From teeth to ethnicity: A neural network approach to predicting population of origin through dental traits and anomalies.","authors":"Suraj Kataria, Rohan Shinkre, Sonal Jain, Kallur Nava Saraswathy, Mohinder Pal Sachdeva, Kp Mohan Kumar","doi":"10.4103/jomfp.jomfp_546_23","DOIUrl":"10.4103/jomfp.jomfp_546_23","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the prevalence of dental traits and anomalies in five North Indian populations (Khas Bodhi, Jaat, Khatri, Garhwali, and Gujjar) and predict the population of origin based on these traits and anomalies for forensic applications.</p><p><strong>Methods: </strong>We assessed dental traits and anomalies in 454 individuals through intraoral examination. Neural network analysis was employed to predict the population of origin based on a combination of dental traits and anomalies.</p><p><strong>Results: </strong>Shovel-shaped incisors exhibited the highest prevalence among the studied traits and anomalies, occurring in 65.4% of the sample. Moreover, shovel-shaped incisors were found to be the most important predictor of population. Neural network analysis indicated that the most accurate population prediction among the studied populations was for the Garhwali origin, achieving a recall rate of 78.3%. While this may appear relatively low, it is crucial to emphasise that the proposed method serves as a corroborative tool for various forensic investigations.</p><p><strong>Conclusion: </strong>This study suggests that dental traits and anomalies can be valuable in predicting the population of origin within Indian populations for forensic purposes. The work enhances the forensic identification process by providing an additional layer of evidence for consideration in identifying both individuals and their ethnic backgrounds. Further research is necessary to enhance the robustness of prediction models.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"515-525"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular Leiomyoma of oral cavity: A case report in young male patient.","authors":"Priyanka Agarwal, Adriana D Creanga","doi":"10.4103/jomfp.jomfp_138_23","DOIUrl":"10.4103/jomfp.jomfp_138_23","url":null,"abstract":"<p><p>Vascular Leiomyoma of the oral cavity is an uncommon benign soft tissue neoplasia arising from the tunica media of the smooth muscle cells. We reported a rare case of Vascular Leiomyoma involving the retromolar trigone area of a young man. A 24-year-old male presented with a slowly growing mass in the retromolar area, which was associated with pain and difficulty in opening of mouth and eating and drinking. A punch biopsy was taken and sent for histopathological examination which revealed a benign angiomatous lesion. The mass was excised, and the adjoining area was curetted. Histopathological examination confirmed the diagnosis of Vascular Leiomyoma. The immunohistochemistry of cells shows: alpha-smooth muscle (+); vimentin (+), Desmin, actin (+), and S100 (-). Angioleiomyomas are benign lesions, but malignant transformation is a possibility so careful histologic inspection is necessary to distinguish these lesions from their malignant counterpart.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"506-510"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The imperative role of oral pathologists in paediatric dental practice.","authors":"Nikhil Srivastava","doi":"10.4103/jomfp.jomfp_194_24","DOIUrl":"https://doi.org/10.4103/jomfp.jomfp_194_24","url":null,"abstract":"","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 3","pages":"361"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}