Journal of Oral and Maxillofacial Pathology最新文献_第9页

Glucose-6-phosphate dehydrogenase enzyme deficiency as a diagnostic factor of diabetes mellitus: An original study. 作为糖尿病诊断因素的葡萄糖-6-磷酸脱氢酶缺乏症：一项原创性研究。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_295_23

Prachi R Sharma, Dharmesh G Vasavada, Rashmi G S Phulari

{"title":"Glucose-6-phosphate dehydrogenase enzyme deficiency as a diagnostic factor of diabetes mellitus: An original study.","authors":"Prachi R Sharma, Dharmesh G Vasavada, Rashmi G S Phulari","doi":"10.4103/jomfp.jomfp_295_23","DOIUrl":"10.4103/jomfp.jomfp_295_23","url":null,"abstract":"Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common genetic disorders affecting approximately 400 million people worldwide. Several recent studies have reported a relationship between G6PD deficiency and the incidence of diabetes.Objectives: The aim of the present study was to evaluate and compare levels of G6PD deficiency in diabetes mellitus patients.Materials and methods: G6PD activity and fasting glucose levels were measured in blood samples of 49 diabetic patients and 21 healthy controls.Results: G6PD activity was decreased in patients with diabetes mellitus as compared to healthy controls and showed that overall G6PD deficiency was significantly associated with diabetes mellitus as compared to nondiabetics.Conclusion: The study concluded that G6PD deficiency is noted in diabetics than in nondiabetics and can be a biomarker of oxidative stress and poor glycemic control in diabetes mellitus.","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 1","pages":"96-99"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple myeloma as a mandibular primary - Dilemma in diagnosing rare tumours of the mandible. 下颌骨原发多发性骨髓瘤--诊断下颌骨罕见肿瘤的难题。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_297_23

Padmaraj J Hegde, Malavika Ramesh, Vijith V Shetty, Sunil Kumar

引用次数: 0

Appearances can be deceptive - Innocuous swelling on the gingiva masking an aggressive lesion within the maxilla. 外表可能具有欺骗性--牙龈上的无害肿胀掩盖了上颌骨内的侵袭性病变。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_205_23

Piyush Thakare, Nilima L Prakash, Aarti M Mahajan, Chetan J Bhadage

引用次数: 0

Erratum: Immunohistochemical expression of paxillin in ameloblastoma and odontogenic keratocyst: An observational study. 更正：paxillin 在牙釉质母细胞瘤和牙源性角化囊肿中的免疫组化表达：一项观察性研究。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_96_24

引用次数: 0

A rare case of undifferentiated pleomorphic sarcoma affecting the mandible - A case report. 一例罕见的下颌骨未分化多形性肉瘤--病例报告。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_142_23

Monalisha Mahapatra, Abikshyeet Panda, Harish Kumar, Lipsa Bhuyan

引用次数: 0

Epidermoid cyst of the midline neck in an 8-year-old girl: A case report. 一名 8 岁女孩的颈中线表皮样囊肿：病例报告。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_69_23

Himani Tiwari Chaturvedi, Chandrashekher Chaturvedi, Smitha Thammaiah, Paresh Kumar Damor

引用次数: 0

Immunohistochemical evaluation of yes-associated protein molecule in the odontogenic epithelium of different histopathological variants of ameloblastoma and unicystic ameloblastoma. 对不同组织病理学变异型牙釉质母细胞瘤和单囊性牙釉质母细胞瘤的牙源性上皮细胞中的 "是 "相关蛋白分子进行免疫组化评估。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_215_23

Bodhiswata Pattnaik, Sweta Mohanty, Surya Narayan Das, Rachna Rath, Archana Bhatta, Sourav Mishra

{"title":"Immunohistochemical evaluation of yes-associated protein molecule in the odontogenic epithelium of different histopathological variants of ameloblastoma and unicystic ameloblastoma.","authors":"Bodhiswata Pattnaik, Sweta Mohanty, Surya Narayan Das, Rachna Rath, Archana Bhatta, Sourav Mishra","doi":"10.4103/jomfp.jomfp_215_23","DOIUrl":"10.4103/jomfp.jomfp_215_23","url":null,"abstract":"Background: Ameloblastoma is one of the major odontogenic neoplasms with an invasive and recurrence potential. Its tumourigenesis and proliferative capacity can be attributed to the activation or inactivation of certain molecular signalling pathways. Hippo signalling pathway is known to regulate diverse physiological processes related to mitosis and organ growth and is an emerging tumour suppressor pathway, the dysfunction of which is implicated in various diseases including cancers. Yes-associated protein1 (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the downstream effectors in the Hippo cascade, which on nuclear activation leads to cellular proliferation in various tumours.Aim: The current study was undertaken to evaluate the expression of YAP in various histopathological variants of ameloblastoma and unicystic ameloblastoma.Materials and methods: Fifty formalin-fixed paraffin-embedded tissue samples of histopathologically diagnosed cases of ameloblastoma, and 10 histopathologically diagnosed cases of unicystic ameloblastoma were obtained from the departmental archives to evaluate the immunohistochemical expression of YAP both manually and by software analysis.Results: More than 90% of cases of conventional ameloblastoma and unicystic ameloblastoma elicited positive expression of YAP. No statistical difference was found among different histopathological variants of conventional ameloblastoma. Significant difference between the means of all four quantitative score groups was observed.Conclusion: In view of the modulating effect of YAP in tumourigenesis and its higher expression in ameloblastoma, further exploration of this molecule appears to be a promising area of research.","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 1","pages":"49-55"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantum dots: The trailblazers of early detection. 量子点：早期检测的开拓者

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_377_23

Pushpanjali Das, Revati S Deshmukh

{"title":"Quantum dots: The trailblazers of early detection.","authors":"Pushpanjali Das, Revati S Deshmukh","doi":"10.4103/jomfp.jomfp_377_23","DOIUrl":"10.4103/jomfp.jomfp_377_23","url":null,"abstract":"Considering the robust awareness of early detection among oral clinicians and patients the increasing imposition of better methods for screening of oral precancerous/cancerous lesions has become imperative. Although histopathology has been considered the indispensable gold standard, it has its pros and cons, as sometimes the diagnosis is compromised with the variabilities subject to the histopathologist under concern. In the realm of oral healthcare, one pioneering trailblazer is making waves, which are 'quantum dots'. Quantum dots are poised to transform the landscape of oral precancer and cancer screening. These nano-sized semiconductor particles possess extraordinary properties that set them apart from conventional detection methods. Their ability to emit distinct wavelengths of light when excited makes them ideal candidates for early detection. The keywords were pitched in and the research literature from the last 15 years (2008-2022) was extirpated to find out the information that existed, the discrepancies and the void left for upcoming research. Its nature and ingenuity have given rise to a transformative approach that holds the potential to redefine the future of oral healthcare. With each breakthrough, we edge closer to a world where the early detection of oral precancerous/cancerous lesions becomes the norm rather than the exception.","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 1","pages":"100-105"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative evaluation of alkaline ionized water and normal water on oral microbial flora: An in-vitro study. 碱性离子水和普通水对口腔微生物菌群的比较评估：体外研究

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_368_23

Pranav R Kurup, Rahul R Patel, R Suraja, Mayur Mishra

{"title":"Comparative evaluation of alkaline ionized water and normal water on oral microbial flora: An in-vitro study.","authors":"Pranav R Kurup, Rahul R Patel, R Suraja, Mayur Mishra","doi":"10.4103/jomfp.jomfp_368_23","DOIUrl":"10.4103/jomfp.jomfp_368_23","url":null,"abstract":"Background: Various artificial chemical agents have been evaluated over many years with respect to their antimicrobial effect in oral cavity. The gold standard for removal of plaque is usage of chlorhexidine, but it can cause alteration in taste sensation and staining of teeth. Electrolytes and oxidizing water may be useful against microbes, but its clinical application has still not been evaluated. Hence this present study was conducted to evaluate the effectiveness of the alkaline ionized water on oral microbial flora.Materials and methods: Ten non-carious, un-restored and intact freshly extracted human teeth were collected and sectioned using a round bur. Each tooth was sectioned longitudinally in two parts and stored in closed sterile containers which was filled with alkaline ionized water (Group 1) and normal water (Group 2), respectively for 15 days. The microbial growth was analyzed prior to dipping in the solutions, 3 days, 7 days and 15 days. The pH of alkaline ionized water and normal water was evaluated using pH meter before placing teeth in different solutions. Results were analyzed using t-test and the level of significance was set at ≤ 0.05.Results: No difference in bacterial colony was observed before test and after 3 days among Group 1 and Group 2, respectively. After 7 days and 15 days, statistically significant decrease in bacterial colony count was seen among Group 1 as compared to Group 2 (P ≤ 0.05).Conclusion: It was then concluded that alkaline ionized water can be effective in reduction of oral microbial flora.","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 1","pages":"62-69"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Honorary president, IAOMP - message. IAOMP 名誉主席 - 致辞。

Journal of Oral and Maxillofacial Pathology Pub Date : 2024-01-01 Epub Date: 2024-04-15 DOI: 10.4103/jomfp.jomfp_90_24

Puneet Ahuja

引用次数: 0