{"title":"Paediatric oral hyaline ring granuloma associated with an impacted tooth and its management preserving the tooth germ: A case report.","authors":"Jaspreet Kaur Deo, Pravesh Mehra, Shailaja Shukla","doi":"10.4103/jomfp.jomfp_391_21","DOIUrl":"10.4103/jomfp.jomfp_391_21","url":null,"abstract":"<p><p>Oral hyaline ring granuloma is an unusual granulomatous lesion affecting the jaws characterized by the presence of numerous eosinophilic rings with multinucleated giant cells. The lesion can be of central or peripheral variety, caused by the impaction of foreign particles in the oral cavity. While literature describes this lesion in association with dentures, carious teeth and extraction socket, this paper reports the first case of an oral hyaline ring granuloma associated with an impacted premolar tooth and its surgical management.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"325-327"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Preethi Ramesh, C V Divyambika, Aravind S Warrier, Leena Dennis Joseph
{"title":"Clinical management of bullous pemphigoid-The importance of cytology in diagnosis.","authors":"Preethi Ramesh, C V Divyambika, Aravind S Warrier, Leena Dennis Joseph","doi":"10.4103/jomfp.jomfp_544_23","DOIUrl":"10.4103/jomfp.jomfp_544_23","url":null,"abstract":"<p><p>Bullous pemphigoid (BP) is a common immune-mediated blistering disorder with predominant skin involvement and occasionally oral manifestations. Vesiculobullous lesions of the oral mucosa present with similar clinical features, and hence arriving at a clinical diagnosis is aided by a valuable chairside investigation, exfoliative cytology. Cytology done in the present case ruled out pemphigus because of the absence of Tzanck cells in the smear. Biopsy and direct immunofluorescence further confirmed the diagnosis of BP. Treatment initiated with systemic steroids and immunomodulators, along with oral topical application of triamcinolone acetonide resulted in complete remission in 2 months. This case report highlights the role of cytology in the diagnosis of vesiculobullous lesions and management protocol for BP patients presenting with simultaneous skin and oral lesions.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"328-331"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative cytopathological investigatory aids in the diagnosis of salivary gland lesions.","authors":"S Vidyalakshmi, K Shanmugasamy","doi":"10.4103/jomfp.jomfp_132_24","DOIUrl":"10.4103/jomfp.jomfp_132_24","url":null,"abstract":"<p><p>Salivary gland lesions are a group of heterogeneous lesions inclusive of non-neoplastic and neoplastic lesions. History, clinical examination and preoperative investigations attempt to minimise the challenges faced in diagnosing these diverse lesions. Preoperative investigations include imaging and cytopathology. The advent of onsite evaluation methods to ensure sample adequacy and newer reporting systems that assign risk of malignancy has improved the sensitivity and specificity of cytopathology. The scope of this review is limited to the preoperative cytopathological investigations and the diagnostic challenges met in reporting salivary gland tumours.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"172-177"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of C-reactive protein, IL-6, and D-dimers in prediction of severity of coronavirus disease 2019: A pilot study.","authors":"Pramod Jahagirdar, Kalpesh Vaishnav, Niharika Abhay Sarathy, Harneet Singh, Komal Kumia, Abhishek Banerjee","doi":"10.4103/jomfp.jomfp_28_24","DOIUrl":"10.4103/jomfp.jomfp_28_24","url":null,"abstract":"<p><strong>Background: </strong>The global outbreak of coronavirus disease 2019 (COVID-19) presents numerous obstacles for healthcare professionals. The present study aimed to evaluate and compare the role of serum biomarkers like- C-reactive protein (CRP), interleukin-6 (IL-6), and D-dimers in the severity of COVID-19 infection.</p><p><strong>Methodology: </strong>A cross-sectional, observational retrospective pilot study was conducted in Udaipur, Rajasthan, wherein data was collected from 250 subjects, out of which, data of 100 subjects were included as per the inclusion criteria. The data was recorded retrospectively among the health professionals via Google Forms in Udaipur, Rajasthan.</p><p><strong>Results: </strong>There were 1 (1%), 3 (3%), 31 (31%) and 65 (65%) participants with minor elevation (0.3-1.0), moderate elevation (1-10), marked elevation (10-50) and severe elevation (>50) of CRP respectively. The difference between the groups was statistically highly significant with a significantly higher number of study participants with a severe elevation of CRP levels (χ<sup>2</sup> = 107.84, <i>P</i> < 0.001). The results showed that there was a significant difference between the groups with IL6 in 0-7 range while 96 (96%) study participants had >7 IL6, and the difference was statistically highly significant (2 = 84.640, <i>P</i> 0.001).</p><p><strong>Conclusion: </strong>In conclusion, the existing body of research indicates a discernible correlation between COVID-19 infection and the fluctuation of biomarker levels. This supplement has the potential to be utilised in clinical practice as a means of informing treatment decisions and determining the necessity of admission to the intensive care unit (ICU).</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"205-210"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Shivananda, Vidya G Doddawad, C S Vidya, S Sowmya
{"title":"Unusual presentation of primary central xanthoma of the maxilla associated with impacted canine: An update on immunohistochemistry in the diagnosis.","authors":"S Shivananda, Vidya G Doddawad, C S Vidya, S Sowmya","doi":"10.4103/jomfp.jomfp_303_23","DOIUrl":"10.4103/jomfp.jomfp_303_23","url":null,"abstract":"<p><p>A xanthoma is an extremely rare condition that affects the soft tissues and bones and is characterized by a predominance of lipid-rich foamy histiocytes. The onset of xanthomas is frequently accompanied by primary or secondary hyperlipidemia. Primary bone xanthomas are very uncommon benign bone lesions that are not linked to hyperlipidemia. Histopathologically, they are distinguished by histiocytes, an abundance of foam cells or xanthoma cells that contain lipids, and a paucity of multinucleated giant cells. There have only been four reports of primary maxillary xanthoma in the medical literature. We present a rare primary intrabony xanthoma of the anterior maxilla in a 23-year-old normolipidemic female patient with solitary radiolucency. Using CD68, S-100, and CD1a immunohistochemical staining, it is possible to distinguish between macrophage/non-Langerhans histiocytes and Langerhans histiocytes. Therefore, a diagnosis of a central xanthoma of the jaws must be made.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"332-336"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T L Yogesh, Anjani Kumar Jha, Sindhumati Jayaraman, Vidhya Jayaraman
{"title":"Low-grade dermatofibrosarcoma protuberance - A rare case report.","authors":"T L Yogesh, Anjani Kumar Jha, Sindhumati Jayaraman, Vidhya Jayaraman","doi":"10.4103/jomfp.jomfp_135_23","DOIUrl":"10.4103/jomfp.jomfp_135_23","url":null,"abstract":"<p><p>Dermatofibrosarcoma protuberans (DFSP) is a slow-growing, soft-tissue tumour of early or mid-adult life, affecting both the genders equally. The most common sites are soft tissue of the trunk (50 to 60%), followed by proximal extremities (20 to 30%) and the head and neck region (10 to 15%). Its metastatic potential is low though the local recurrence rate is high. Here, we report a case of a female patient with a large soft tissue growth located at the right cheek, chin and neck region. Local excision was done under the impression of a benign tumour such as lipoma or sebaceous cyst. Histological evaluation showed bland spindle cells arranged in a storiform pattern questioning the provisional diagnosis of the lesion. Further evaluation with the immunohistochemistry (IHC) panel confirmed the diagnosis of DFSP. Since it is a rare tumour of the head and neck region with non-alarming initial presentation and the potential for erroneous diagnosis as another lesion, we present a case of DFSP.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"315-320"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amitha J Lewis, K Rammohankumar, Hema Kini, Karen Boaz
{"title":"Parasitic colloid cyst: A diagnostic dilemma.","authors":"Amitha J Lewis, K Rammohankumar, Hema Kini, Karen Boaz","doi":"10.4103/jomfp.jomfp_162_23","DOIUrl":"10.4103/jomfp.jomfp_162_23","url":null,"abstract":"<p><p>The pathologies of the neck are varied and at times may cause a diagnostic dilemma for the pathologist. In this report, we present a case of a 32-year-old man with a slow-growing nodular swelling in the right neck region, which was diagnosed as a simple colloid cyst arising in a parasitic thyroid nodule. Simple colloid cysts are cysts that develop due to impaired accumulation of thyroglobulin in inactive follicles. Most thyroid-related pathologies occur as midline swellings. However, the present case was unique due to its location with no connection to the thyroid gland. This case report describes the diagnostic process and adds insight into the pathology of a colloid cyst.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"321-324"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tribikram Debata, Anuroopa Mohapatra, Sujit Ranjan Sahu, Upasana Das
{"title":"Rare case of extrapulmonary tuberculosis masquerading as an intraoral sinus in association with a nonhealing extraction socket in a teenage girl-\"A case report with Review of literature\".","authors":"Tribikram Debata, Anuroopa Mohapatra, Sujit Ranjan Sahu, Upasana Das","doi":"10.4103/jomfp.jomfp_304_23","DOIUrl":"10.4103/jomfp.jomfp_304_23","url":null,"abstract":"<p><p>Tuberculosis (TB) is a serious infectious disease with significant mortality and most commonly affects the pulmonary system and rarely the oral cavity. Because oral tuberculosis is a rare disease, it is often overlooked in the differential diagnosis of oral lesions. Despite the recent decline in the incidence of tuberculosis, it remains a highly contagious and serious public health problem, thus requiring early diagnosis and rapid intervention. Extrapulmonary tuberculosis (EPTB) is defined as any bacteriologically confirmed or clinically diagnosed case of tuberculosis (TB). A 17-year-old girl reported at the outpatient Department of Dentistry with the chief complaint of a swelling at the backside of mouth along with pus discharge. She noticed these symptoms approximately one month after the extraction of the left mandibular first molar. The patient was referred to the Department of Pulmonary Medicine for further investigation and treatment. Subsequently, diagnosis of EPOTB was reached on the basis of the histopathological findings and the previous personal as well as family history. Drastic improvement was observed in the general condition and a complete resolution of the oral lesion after four weeks of ATT and the patient was completely free of all the symptoms after six months of follow-up period. This case demonstrated the importance of oral manifestation of oral tuberculosis for dentist who may be the first healthcare provider to encounter a variety of oral lesions.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"301-306"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Salivary α-amylase as a stress biomarker in mentally and physically disabled individuals during COVID-19 times.","authors":"Ashish Gaurav, Gaganjot Kaur Sharma, Ajay Chhabra, Sakshi Bamba, Sabashish Sahoo, Vandana Chhabra","doi":"10.4103/jomfp.jomfp_462_23","DOIUrl":"10.4103/jomfp.jomfp_462_23","url":null,"abstract":"<p><strong>Background: </strong>Stress is faced by every individual in their day-to-day life activities. During pandemic, most people have experienced multiple episodes of depression, anxiety, and insomnia. Several medical and dental problems are reported with stress and the fastest and easiest way to study and investigate is through body fluids, mainly saliva. Hence, we aim to study salivary α amylase in disabled individuals and hypothesize that salivary α amylase could be a reliable stress biomarker in disabled individuals.</p><p><strong>Materials and methods: </strong>Cross-sectional study was conducted including 200 individuals grouped into controls (100) and disabled individuals (100). Disabled individuals were further grouped into physically (50) and mentally (50) disabled. Stimulated and unstimulated saliva was collected from all the participants and were investigated for salivary α-amylase by direct substrate method. The enzyme activity was analyzed using a spectrophotometer and the obtained were analyzed statistically.</p><p><strong>Result: </strong>Salivary α-amylase showed significant difference between controls and disabled group (p = 0.000). Salivary α-amylase was least in the mentally disabled group compared to physically disabled group. Age related comparison of salivary α-amylase was higher in physically disabled whereas gender related comparison showed females in physically disabled group to be more affected than controls.</p><p><strong>Conclusion: </strong>Saliva, the easy and most researched fluid, is rich in salivary α-amylase. Salivary α-amylase is a potential biomarker to assess stress. Further diagnostic studies are required to know the salivary changes and their influence on individual general health status.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"178-181"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dean's Perspective of Oral Pathology.","authors":"V Ramesh","doi":"10.4103/jomfp.jomfp_168_24","DOIUrl":"https://doi.org/10.4103/jomfp.jomfp_168_24","url":null,"abstract":"","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 2","pages":"170-171"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}