Journal of Oral and Maxillofacial Pathology最新文献

{"title":"Anti-biofilm effect of clove oil against <i>Candida albicans</i>: A systematic review.","authors":"J Palaskar Sangeeta, O Balsaraf Aishwarya, D Balsaraf Omkar, N Bhave Madhura","doi":"10.4103/jomfp.jomfp_225_24","DOIUrl":"10.4103/jomfp.jomfp_225_24","url":null,"abstract":"<p><p>In recent years, <i>Candida albicans</i> has emerged as a significant opportunistic pathogen, causing various infections, particularly in immunocompromised geriatric individuals. One of the major hindrances in managing <i>Candida</i> infections lies in its potential to develop and survive in biofilms, which demonstrate resistance to conventional antifungal therapies, thereby complicating treatment strategies. While clove oil has shown promising results as a potential antifungal agent, its specific anti-biofilm effects against <i>Candida albicans</i> biofilms remain relatively underexplored. Therefore, there is a need for a comprehensive review to evaluate the existing literature on the anti-biofilm properties of clove oil and its mechanisms of action against <i>Candida albicans</i> biofilms. Such a review will provide valuable insights into the potential therapeutic applications of clove oil in combating biofilm-associated <i>Candida</i> infections. This review will enable us to infer and understand the potential effects of clove oil against <i>Candida albicans</i>. This systematic review aims to determine the anti-biofilm efficacy of clove oil against <i>Candida albicans</i>. This systematic review was registered in 'PROSPERO' (CRD42024524134) and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The literature searches used Google Scholar, PubMed, and Science Direct databases. All original studies published in English from 2004 to 2023 were included. From 37 studies found online, only four were reviewed. Results showed that clove oil had significant anti-biofilm activity when assessed against <i>Candida albicans</i>. Our systematic review provides insights into clove oil's potential as a therapeutic agent against <i>Candida albicans</i> biofilms. Clove oil also represents a promising avenue for future research and development in managing <i>Candida biofilms</i>.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"665-671"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The oral-lung microbiome dysbiosis: Unravelling its role in implications for chronic obstructive pulmonary disease (COPD) pathogenesis.","authors":"Nimisha Mithradas, Uma Sudhakar, K Shanmugapriya, Nadeem Jeddy, Shankar Ram","doi":"10.4103/jomfp.jomfp_277_24","DOIUrl":"10.4103/jomfp.jomfp_277_24","url":null,"abstract":"<p><strong>Background: </strong>The impact of the oral flora on the composition of the microbiome in the lungs is substantial in both healthy and diseased conditions, contributing significantly to its intricacy. There is mounting evidence from microbiological research that suggests a major ecological relationship between periodontitis, Chronic Obstructive Pulmonary Disease (COPD), and oral microecosystems. An association has been established between respiratory diseases and disruptions in the symbiotic equilibrium of the oral microbiome. This study aims to explore the intricate connections between oral health and lung microflora, particularly about the pathogenesis of COPD, and to highlight the implications for future research and clinical practice.</p><p><strong>Materials and methods: </strong>Subgingival Plaque samples were collected from a total of 120 participants with 30 healthy Control (H group),30 Periodontitis with no COPD (P group), 30 COPD with periodontally healthy (COPD) and 30 individuals with COPD and Periodontitis (COPD+ P). All participants underwent evaluation of periodontal measurements like Pocket Depth (PD), Clinical loss of Attachment (CAL), Gingival Index (GI), and Plaque Index (PI) Bacterial DNA was extracted and quantified using Real-time polymerase chain reaction. Using the One-dimensional Analysis of Variance (ANOVA) and post-analysis test for multiple comparisons, the mean values of all the clinical parameters were analyzed among the four participant groups. Using the Pearson Correlation coefficient, the parameters were correlated.</p><p><strong>Results: </strong>Statistical relevant relation was shown among Probing Depth (PD), Clinical Loss of Attachment (CAL), Plaque Index (PI) and Gingival Index (GI) in the COPD+P group. Increased prevalence of Pa (<i>Pseudomonas aeroginosa</i>) seen among <i>P</i> group and COPD+P. A substantial inverse relationship was seen between the absolute levels of Pa, CAL, PI, and lung function measures (Fev1, Fev1/FVC).</p><p><strong>Conclusion: </strong>The importance of maintaining dental health in the prevention and treatment of respiratory disorders is highlighted by the relationships that exist between the oral microecosystem, oral hygiene, and respiratory pathologies. There is substantial potential to decrease the occurrence of respiratory illnesses by practicing good oral care and strategically managing the balance of the oral microbial flora. Therefore, future research efforts should prioritize the characterization of the precise impact of the oral microbiota on pulmonary health and use this knowledge towards developing innovative preventive and treatment measures targeted at combating respiratory infections and related diseases.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"619-625"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive analysis of odontogenic tumors according to recent WHO (2022) classification: An institution-based retrospective study.","authors":"Piyush Asnani, Shireen Ali, Sima Odedra, Jayasankar Pillai, Namrata Jayasheel, Ranjit Jadeja","doi":"10.4103/jomfp.jomfp_56_24","DOIUrl":"10.4103/jomfp.jomfp_56_24","url":null,"abstract":"<p><strong>Background: </strong>Odontogenic tumors constitute a rare group of lesions with diverse characteristics originating from tooth-forming tissues, primarily within the maxillofacial region. Variations in incidence across populations in India and with changes incorporated in successive World Health Organization (WHO) classifications, necessitate continued research to understand their epidemiology.</p><p><strong>Objective: </strong>This retrospective study aims to provide an extensive analysis of Odontogenic tumors reported in a dental institute in Gujarat, India, using the 5^th edition of the WHO classification. The study also seeks to compare the findings with data from other regions.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on archived histopathological records from the Oral Pathology department of our institute, spanning from 1966 to 2023. This analysis focused on demographic details, tumor types, and their distribution. The data were reclassified according to the WHO 5^th edition and subjected to descriptive statistical analysis.</p><p><strong>Results: </strong>Among 10,907 biopsies, 501 cases (4.6%) were diagnosed as Odontogenic tumors, with 97.6% being benign. Benign epithelial tumors, predominantly Ameloblastoma (68.9%) was most common. Supporting their rare occurrence malignant cases included Ameloblastic carcinoma (2.2%) and Clear Cell Odontogenic Carcinoma (0.2%). An overall male predominance (51.7%) was noted, with female dominance in Adenomatoid Odontogenic tumor (60%), Cemento-Ossifying Fibroma (62.5%), Odontogenic fibroma (91%), and Odontogenic Myxoma (66.7%). Most cases occurred in the third decade (27.1%), with a notable mandibular predominance (78%).</p><p><strong>Conclusion: </strong>The findings contribute to the understanding of Odontogenic tumors epidemiology, emphasizing the importance of further regional studies and adapting to evolving classifications for accurate assessments and cross-population comparisons.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"576-582"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The chronicles of green complex bacteria.","authors":"Moitri Ojha, Amrita, Disha Gupta, Vartika Verma","doi":"10.4103/jomfp.jomfp_121_24","DOIUrl":"10.4103/jomfp.jomfp_121_24","url":null,"abstract":"<p><p>Periodontal pathogens have always captivated the attention of periodontists and microbiologists as it account for causing periodontal disease in 90% of the population globally. Clinical and experimental studies have confirmed that destructive activity on the periodontium is due to certain strains of bacteria that occupy a relatively small portion of dental biofilm. Among them, the green and the red complex bacteria enjoy the popularity of being the most notorious strain in disease initiation and progression. The genera of green complex bacteria comprise three pathogens- <i>Aggregatibacter actinomyecetecomitans</i>, <i>Capnocytophaga</i>, and <i>Eikenella corrodens</i>. The group possesses several stratagems and key elements that aid them in escaping the immune surveillance and creating a harsh environment for the periodontium. The review focuses on defining the green complex bacteria and their role in periodontitis.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"633-640"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of <i>porphyromonas gingivalis</i> in oral potentially malignant disorders and oral squamous cell carcinoma using qRT-PCR: A comparative study.","authors":"G Suganya, N S Sahana, P Akalya, Satish T Yadav, T Suresh, J Chandrakala","doi":"10.4103/jomfp.jomfp_119_24","DOIUrl":"10.4103/jomfp.jomfp_119_24","url":null,"abstract":"<p><strong>Background: </strong>Recent researches has shown a significant association between microorganisms and oral squamous cell carcinoma (OSCC). <i>Porphyromonas gingivalis</i>, the keystone pathogen in chronic periodontitis, is considered as an important potential etiologic agent of OSCC, but the underlying mechanisms by which <i>P. gingivalis</i> mediates OSCC progression remain poorly understood.</p><p><strong>Aim: </strong>The aim of this study was to compare the levels of <i>P. gingivalis</i> in oral potentially malignant disorders, oral squamous cell carcinoma and normal oral mucosa using qRT-PCR.</p><p><strong>Method and material: </strong>Genomic DNA was extracted and quantified, and the expression of the <i>P. gingivalis</i> levels was done in 16 cases of oral potentially malignant disorders, 16 cases of oral squamous cell carcinoma and 16 cases of normal oral mucosa by quantitative real-time polymerase chain reaction (RT-qPCR).</p><p><strong>Results: </strong>It was observed that there was an over expression of <i>P. gingivalis</i> in both oral potentially malignant disorders and oral squamous cell carcinoma with good mean cycle threshold (CT) value of 27.00 and 27.55, respectively. When comparing the levels of <i>P. gingivalis</i> in three groups, oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC) showed higher expression than normal mucosa and in between two groups OSCC showed higher expression than OPMD and the difference is statistically significant with <i>P</i> value less than 0.001.</p><p><strong>Conclusion: </strong>Our findings suggest that there is an over expression of <i>P. gingivalis</i> in oral potentially malignant disorders and oral squamous cell carcinoma, compared to normal mucosa and highly expressed in OSCCs compared to OPMD. Increased levels of <i>P. gingivalis</i> in OPMDs and OSCCs may suggest the early event of tumorigenesis. Hence, it can be used as a valuable marker for early diagnosis, prognosis marker and in the identification of therapeutic targets.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"583-588"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of clinical and histopathological changes in leukoplakia using curcumin lozenges based on revised WHO criteria- A pilot study.","authors":"Parul Khare, Anshu Gupta Devra, Madhvika Patidar, Rohit Punga, Nirupama Gupta, Soo-Yeon Sohn","doi":"10.4103/jomfp.jomfp_227_24","DOIUrl":"10.4103/jomfp.jomfp_227_24","url":null,"abstract":"<p><strong>Introduction: </strong>Oral epithelial dysplasia, such as leukoplakia has a risk of malignant transformation. Curcumin, a natural polyphenol with anticancer properties, has been explored for many years as an alternative treatment for leukoplakia.</p><p><strong>Aim: </strong>To evaluate clinical and histopathological changes in oral leukoplakia from curcumin lozenges, this study compares pre- and post-medication effects. It is the first to involve general and oral pathologists from India and the USA, who independently assessed changes using WHO 2022 criteria.</p><p><strong>Material and method: </strong>The study involved 10 patients and was conducted in three phases. Initial biopsy, and administration of curcumin lozenges (2 tablets thrice daily for 3 months) with clinical evaluation every month followed by a second biopsy.</p><p><strong>Results: </strong>Post-medication, clinically in a few cases reduction of lesion size was observed as a change from white to gray patches. Histopathological analysis was subjective and the three experts reported an overall improvement in architectural as well as cytological features suggesting the possible use of curcumin in treating cases of mild dysplasia.</p><p><strong>Conclusion: </strong>The pilot study suggests curcumin lozenges may benefit leukoplakia patients, but the small sample size limits definitive conclusions. Larger studies are needed to confirm these findings and assess long-term efficacy. WHO 2022 criteria showed subjectivity and variability. Despite this, they were useful for identifying specific changes. To the best of our knowledge to date, no other study has validated these WHO 2022 features in repeated biopsies.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"626-632"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pleomorphic adenoma with extensive squamous metaplasia and keratinizing cysts: Diagnostic and clinical pitfalls - A report of two cases and review of literature.","authors":"Mahadevi B Hosur, Rudrayya S Puranik, Satyajit G Dandagi, Vivekanand M Patil","doi":"10.4103/jomfp.jomfp_151_24","DOIUrl":"10.4103/jomfp.jomfp_151_24","url":null,"abstract":"<p><p>Pleomorphic adenoma is the most common benign tumour of major or minor salivary glands. Histological diversity is the hallmark of pleomorphic adenoma. Extensive squamous metaplasia with keratin-filled cysts is rarely reported. Here we present two cases of pleomorphic adenoma with exuberant squamous metaplasia and keratin filled cysts formation in a minor salivary gland and discuss its potential diagnostic pitfalls.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"689-693"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The outcomes between cystic decompression and marsupialisation methods in odontogenic cysts and cyst-like tumours: A retrospective comparative study.","authors":"Kannika Rungsaeng, Pisha Pittayapat, Sappasith Panya, Paksinee Kamolratanakul","doi":"10.4103/jomfp.jomfp_136_24","DOIUrl":"10.4103/jomfp.jomfp_136_24","url":null,"abstract":"<p><strong>Context: </strong>Marsupialization and decompression are treatments designed to reduce hydrostatic pressure which results in reducing the cystic size and increasing the bone density of the lesion.</p><p><strong>Aims: </strong>To compare the percentage of cystic size reduction and the percentage of change in radiographic density from marsupialisation and two types of decompression: tube drain and stent.</p><p><strong>Settings and design: </strong>Retrospective analysis of panoramic films was conducted to evaluate cystic size and intralesional density.</p><p><strong>Materials and methods: </strong>Data were analysed from 40 cases, including 31 cases of odontogenic cyst and 9 cases of cyst-like tumour, treated at Chulalongkorn University's Faculty of Dentistry from 2009 to 2019. The percentage of cystic size reduction and percentage of change in radiographic density were analysed before the procedure and three months after treatment. The density and size of the odontogenic cysts were determined using Image J software version 1.43.</p><p><strong>Statistical analysis: </strong>Data were analysed using Kruskal-Wallis test.</p><p><strong>Results: </strong>The percentage of cystic size reductions when using marsupialisation, decompression with a tube drain and decompression with a stent were 31.49 ± 7.43, 35.42 ± 10.58 and 30.99 ± 7.16, respectively (<i>P</i> = 0.366). The percentage of change in radiographic density was 25.21 ± 7.04, 27.09 ± 7.96 and 24.94 ± 5.35, respectively (<i>P</i> = 0.661). There was no statistically significant difference in outcomes between the groups.</p><p><strong>Conclusions: </strong>Decompression with a tube drain yielded both the highest percentage of size reduction and the highest percentage of change in radiographic density in the cyst, although this better performance was not statistically significant. We recommend decompression with a tube drain, as it effectively maintains an open drainage pathway and prevents collapse of the cyst opening. This continuous release of hydrostatic pressure is beneficial in promoting gradual bone healing and regeneration.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"612-618"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitosis - predicting primary tumour and metastatic lymph node behaviour and beyond in OSCC - A pilot study.","authors":"Soumya Makarla, Radhika M Bavle, Satyajit Topajiche","doi":"10.4103/jomfp.jomfp_292_24","DOIUrl":"10.4103/jomfp.jomfp_292_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>In the evaluation of oral cancer, mitotic index/mitotic figures are of paramount importance in histopathology. The number of mitoses in tumour cells is directly proportional to the activity of the tumour cells. In this novel study, we evaluated the status of the mitotic figures found in the metastatic deposit of the lymph nodes in addition to the primary tumour. A great deal of significance is given to this parameter in the evaluation of progress of the primary tumours in a state of distant metastasis. Therefore, we propose to analyse the lymph node mitotic index (LMI) in metastatic deposits and its relation to the primary tumour by assessing the relation between primary: LN mitosis ratio (PLMR). This also can provide an insight into the concept of understanding the dynamic state of lymph node deposits in oral squamous cell carcinoma (OSCC).</p><p><strong>Materials and methods: </strong>A total of 510 lymph nodes from 17 cases of surgically treated OSCC were analysed, of which 40 lymph nodes were found to be positive. These 40 lymph nodes were examined histopathologically for the presence of mitotic figures in ten randomly selected fields (x400) and compared to the mitotic activity of the primary tumour by two observers independently, along with other histopathological features. LMI and PLMR were further determined for these cases.</p><p><strong>Observations and results: </strong>The mitotic index was significantly higher in the metastatic deposits than in the primary tumour (<i>P</i> = 0.004). A higher percentage of abnormal mitoses was observed in metastatic lymph nodes, but no statistical significance (<i>P</i> = 0.27) was found when compared with primary tumour. Statistically significant correlation (<i>P</i> = 0.001) was observed between abnormal mitoses (%) and presence of ECS as well as size of the metastatic deposits. The LMI ratio showed a high mitotic rate in close to 80% of the cases. PLMR showed 58-60% cases with mitotically more active lymph nodes.</p><p><strong>Interpretation and conclusion: </strong>This study is the first of its kind, which examines a level further than the nature of the primary tumour. Mitotic index/numbers in lymph nodes (LMI) might be considered an important parameter to evaluate the disease spread, revealing the nature of transiently indolent and mitotically active metastatic lymph nodes. The PLMR adds a further dimension on the lymph node's dynamic status in the progression of the disease.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"602-611"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteochondroma of the anterior mandible: A rare case report and review of the literature.","authors":"Devendra H Palve, Akshay A Dhobley, Dipak D Ghatage, Ashwini G Kendre","doi":"10.4103/jomfp.jomfp_37_24","DOIUrl":"10.4103/jomfp.jomfp_37_24","url":null,"abstract":"<p><p>Osteochondroma (OC) is the most common benign tumour of the axial skeleton which often occurs from the metaphysis of the long bones but rarely occurs in the craniofacial region (<1% of cases). Literature shows that cases occur more in the mandibular condylar region. To date, only six cases of this incredibly rare OC in the mandibular front region have been documented in the last 30 years. In addition to reviewing the literature on OCs of the mandibular front region, this case report describes a case of OC involving the mandibular symphysis and left para-symphysis in a 67-year-old male patient. Histopathological examination revealed chondroid and osteoid tissue with sparse fibrous tissue patches and columns of chondrocytes with single tiny nuclei within the cartilaginous cap, and all these features were strongly suggestive of OC diagnosis.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"28 4","pages":"672-676"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11819633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}