Clinical Medicine Insights. Case Reports最新文献_第3页

Spontaneous Coronary Artery Dissection-Different Faces of the Same Disease. 自发性冠状动脉夹层——同一疾病的不同侧面。

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Clinical Medicine Insights. Case Reports Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251322433

Kinga Kowalik, Małgorzata Wojciechowska, Karol Momot, Izabela Poprawa, Maciej Dąbrowski, Mariusz Kruk, Maciej Zarębiński

引用次数: 0

Ewing Sarcoma Presenting as Fever of Unknown Origin (FUO) in Children: A Case Report and Brief Review of the Literature. 儿童尤文氏肉瘤以不明原因发热（FUO）为表现：1例报告及文献回顾。

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Clinical Medicine Insights. Case Reports Pub Date : 2025-02-26 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251323164

Hasan Arafat, Zahraa Mm Zeer, Almotazbellah Mm Zeer, Mahmoud Noman, Hamza A Abdul-Hafez, Ahmad G Hammouri, Amer Zughayyer

引用次数: 0

Diagnosis and Management of Tuberous Sclerosis Complex in a Resource-Limited Setting-A Case Report of a 14-Year-Old Female Zambian Adolescent. 在资源有限的环境下结节性硬化症的诊断和治疗——一名14岁赞比亚女青少年的病例报告。

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Clinical Medicine Insights. Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251321268

Mwamba Lienda, Meek Mwila, Chilala Sichula, Chishiba Kabengele, Moses Akombwa, Christina Zulu, Chihena Hansini Banda, Hellen M'hango

{"title":"Diagnosis and Management of Tuberous Sclerosis Complex in a Resource-Limited Setting-A Case Report of a 14-Year-Old Female Zambian Adolescent.","authors":"Mwamba Lienda, Meek Mwila, Chilala Sichula, Chishiba Kabengele, Moses Akombwa, Christina Zulu, Chihena Hansini Banda, Hellen M'hango","doi":"10.1177/11795476251321268","DOIUrl":"10.1177/11795476251321268","url":null,"abstract":"Tuberous sclerosis complex (TSC) is a rare multisystemic neurocutaneous syndrome with a wide spectrum of clinical manifestations. We present a case of a 14-year-old adolescent female who presented with a history of facial angiofibromas since the age of 8 months. Physical examination was remarkable for multiple angiofibromas on the face, and other multiple cutaneous manifestations of TSC. MRI of the head, and abdomen revealed cortical tubers, multiple bilateral periventricular and subependymal nodular lesions, calcifications, and bilateral kidney enlargement with multiple bilateral renal angiomyolipomas of varying sizes in a background of bilateral polycystic kidneys, MRI of the chest was unremarkable. A diagnosis of TSC was made using the clinical diagnostic criteria which consist of major and minor features. A diagnosis using genetic studies could not be made due to a lack of resources. Management was multidisciplinary and regular monitoring every 6 months will be required to monitor disease progression and manage complications as they arise. This case illustrates the multidisciplinary approach needed to address the diverse clinical manifestations of TSC and the diagnostic challenges, treatment limitations, and psychological impact of TSC in low-resource settings like Zambia where access to advanced therapies is limited.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251321268"},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Presentation of Chronic Exfoliative Cheilitis: Case Report. 罕见的慢性剥脱性舌炎1例报告。

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Clinical Medicine Insights. Case Reports Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251319981

Abdelrahman Eltoureini, Hamad Alharbi, Wafaa Saleh

{"title":"A Rare Presentation of Chronic Exfoliative Cheilitis: Case Report.","authors":"Abdelrahman Eltoureini, Hamad Alharbi, Wafaa Saleh","doi":"10.1177/11795476251319981","DOIUrl":"10.1177/11795476251319981","url":null,"abstract":"Background: Chronic exfoliative cheilitis is an inflammatory condition of the lips that involves exfoliation of the superficial layers of the lip with continuous peeling, ulceration, and exfoliation. Chronic exfoliative cheilitis can lead to social and psychosocial problems.Case presentation: A 73-year-old diabetic male presented with a lip lesion showing continuous ulceration, crusting, and peeling of the lower lip. It was a spontaneous complaint that had its onset 6 months ago and has constantly evolved. The medical history revealed controlled diabetes mellitus while the social and family histories showed no marked findings. After a careful history, clinical examination, and laboratory investigations with the exclusion of the possible etiologic factors of cheilitis, the patient was diagnosed with chronic exfoliative cheilitis with unknown etiology. Then, the patient was prescribed topical steroids, and he was advised for continuous follow-up visits.Conclusion: Diagnosing chronic cheilitis is challenging and requires careful history, clinical examination, and laboratory investigation, with continuous follow-up to improve the patient's quality of life. Further research is needed to better understand and treat these cases.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251319981"},"PeriodicalIF":0.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin D Deficiency-Induced Proximal Myopathy in a Pediatric Patient During COVID-19 Lockdown: A Case Report. COVID-19封锁期间儿童患者维生素D缺乏引起的近端肌病：一例报告

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Clinical Medicine Insights. Case Reports Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251320006

Mohammad Hazique, Arihant Surana, Aashna Mehta, Helen Huang, Surour Alneyadi, Kavita Shah, Ajeet Singh, Amit Varma, Mahendra Pratap Singh, Sanjit Sah, Amogh Verma

{"title":"Vitamin D Deficiency-Induced Proximal Myopathy in a Pediatric Patient During COVID-19 Lockdown: A Case Report.","authors":"Mohammad Hazique, Arihant Surana, Aashna Mehta, Helen Huang, Surour Alneyadi, Kavita Shah, Ajeet Singh, Amit Varma, Mahendra Pratap Singh, Sanjit Sah, Amogh Verma","doi":"10.1177/11795476251320006","DOIUrl":"10.1177/11795476251320006","url":null,"abstract":"Vitamin D deficiency is a significant public health concern that affects bone health and muscle function in children, especially in developing countries. The COVID-19 pandemic has intensified this issue because lockdowns have reduced sunlight exposure. We report a rare case of a 13-year-old Indian boy who developed severe proximal myopathy induced by vitamin D deficiency during the pandemic. The patient presented with generalized body aches, progressive lower limb weakness, difficulty walking, waddling gait, and a positive Gower's sign. Laboratory tests revealed severe hypovitaminosis D (25[OH]D level, 3.8 ng/ml), hypocalcemia, hypophosphatemia, elevated parathyroid hormone, and elevated alkaline phosphatase levels. Electromyography and nerve conduction study results were normal. The patient was diagnosed with vitamin D deficiency-induced proximal myopathy and osteomalacia, likely due to reduced sunlight exposure, inadequate dietary intake, and obesity. The treatment involved high-dose vitamin D supplementation, oral calcium, lifestyle modifications, and a structured physiotherapy program focusing on resistance training and functional mobility exercises. Despite biochemical normalization after 2 months, significant symptomatic improvement was achieved only after intensifying physiotherapy. By 7 months, the patient had fully recovered muscle strength, achieved normal gait, and maintained normal follow-up laboratory values. This case emphasizes the importance of considering vitamin D deficiency in children with muscle weakness during periods of limited sunlight exposure, and highlights the need for a multidisciplinary approach for effective management and full functional recovery.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251320006"},"PeriodicalIF":0.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ascaris lumbricoides Emerging from a PleurX Draining Catheter: An Unexpected Diagnosis. 胸膜引流管内出现蛔虫：一个意外的诊断。

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Clinical Medicine Insights. Case Reports Pub Date : 2025-01-28 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251315619

Hasan Arafat, Hamza A Abdul-Hafez, Ali Sabateen

引用次数: 0

Acute Pancreatitis: An Unusual Side Effect of Adalimumab in Crohn's Disease Patient. 急性胰腺炎：阿达木单抗在克罗恩病患者中的不寻常副作用。

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Clinical Medicine Insights. Case Reports Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251315000

Walid El Ouardi, Mustapha Benazzouz

{"title":"Acute Pancreatitis: An Unusual Side Effect of Adalimumab in Crohn's Disease Patient.","authors":"Walid El Ouardi, Mustapha Benazzouz","doi":"10.1177/11795476251315000","DOIUrl":"10.1177/11795476251315000","url":null,"abstract":"Background: Drug-induced acute pancreatitis is a rare condition occurs at an incidence rate of 0.1-1.4% and represents a diagnostic challenge. TNFα inhibitors specially adalimumab is very rarely reported in the literature, primarily through case reports, as a potential cause of acute pancreatitis.Case presentation: Our case report presents a case of a 23-year-old patient followed for Crohn disease in whom a diagnosis of acute pancreatitis induced by adalimumab was made. This diagnosis was confirmed after the elimination of other possible etiologies, and notably by the recurrence of pancreatitis after Adalimumab rechallenge. The occurrence of acute pancreatitis induced by TNFα inhibitors exposes to the risk of pancreatitis with other drugs in this class, hence the need to switch to another therapeutic class, which was Ustekinumab in our case.Conclusion: Acute pancreatitis is an unusual complication of treatment with Adalimumab. Through our experience, based on solid scientific data, we want to draw the attention of clinicians to the reality of this complication. It should be considered in any patient on TNFα inhibitors who presents with acute pancreatitis without an obvious cause.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251315000"},"PeriodicalIF":0.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaping: A Safe Alternative to Counteract Smoking? Case Report. 电子烟：一种安全的替代吸烟？病例报告。

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Clinical Medicine Insights. Case Reports Pub Date : 2025-01-16 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251313766

María Cristina Martínez-Ávila, Eugenio Matijasevic Ardila, Alieth Lucía Acosta Cardozo, Cristian Camilo Alvarado Castro, Carlos Eduardo Matiz-Bueno

引用次数: 0

Immune-Complex Mediated Mesangial Proliferative Glomerulonephritis with Full-House Pattern Observed During Treatment of Immune Thrombocytopenic Purpura. 免疫复合物介导的系膜增生性肾小球肾炎伴全屋型在免疫性血小板减少性紫癜治疗期间的观察。

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Clinical Medicine Insights. Case Reports Pub Date : 2024-12-24 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241307123

Ai Ueki, Tsugumi Fukunaga, Hiroyasu Goto, Hitoshi Minakuchi, Naoki Oshima

{"title":"Immune-Complex Mediated Mesangial Proliferative Glomerulonephritis with Full-House Pattern Observed During Treatment of Immune Thrombocytopenic Purpura.","authors":"Ai Ueki, Tsugumi Fukunaga, Hiroyasu Goto, Hitoshi Minakuchi, Naoki Oshima","doi":"10.1177/11795476241307123","DOIUrl":"10.1177/11795476241307123","url":null,"abstract":"This study reports a rare case of immune-complex mediated mesangial proliferative glomerulonephritis (ICGN) with a full-house pattern in a 56-year-old Japanese man, observed during the treatment of immune thrombocytopenic purpura (ITP). Because of persistent complement deficiency and worsening of kidney function, he was treated with prednisolone, and his urinary findings improved markedly. However, as the complement titers were still low, mycophenolate mofetil was also prescribed, which normalized complement levels. Production of anti-platelet antibodies is considered to be involved in the etiology of ITP. Although little is known about the mechanism by which ITP causes glomerulonephritis, including ICGN, glomerular deposition of circulating immune complexes synthesized by antiplatelet antibodies may be involved. This case shows full-house nephropathy, suggesting the involvement of immune complexes, which in turn, suggested an association between ITP and glomerulonephritis.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241307123"},"PeriodicalIF":0.8,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11672467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Unusual Diagnosis of Rectosigmoid Leiomyoma in an Adult: A Rare Case Report. 成人直肠乙状结肠平滑肌瘤的罕见诊断：一罕见病例报告。

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Clinical Medicine Insights. Case Reports Pub Date : 2024-12-20 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241307592

Karam Karam, Houssein Chebbo, Sarah Saleh, Sarah Jalloul, Johny Salem, Karim Al Halabi, Elias Fiani

引用次数: 0