Clinical Medicine Insights. Case Reports最新文献_第2页

Ascaris lumbricoides Emerging from a PleurX Draining Catheter: An Unexpected Diagnosis.

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Clinical Medicine Insights. Case Reports Pub Date : 2025-01-28 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251315619

Hasan Arafat, Hamza A Abdul-Hafez, Ali Sabateen

引用次数: 0

Acute Pancreatitis: An Unusual Side Effect of Adalimumab in Crohn's Disease Patient.

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Clinical Medicine Insights. Case Reports Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251315000

Walid El Ouardi, Mustapha Benazzouz

{"title":"Acute Pancreatitis: An Unusual Side Effect of Adalimumab in Crohn's Disease Patient.","authors":"Walid El Ouardi, Mustapha Benazzouz","doi":"10.1177/11795476251315000","DOIUrl":"10.1177/11795476251315000","url":null,"abstract":"Background: Drug-induced acute pancreatitis is a rare condition occurs at an incidence rate of 0.1-1.4% and represents a diagnostic challenge. TNFα inhibitors specially adalimumab is very rarely reported in the literature, primarily through case reports, as a potential cause of acute pancreatitis.Case presentation: Our case report presents a case of a 23-year-old patient followed for Crohn disease in whom a diagnosis of acute pancreatitis induced by adalimumab was made. This diagnosis was confirmed after the elimination of other possible etiologies, and notably by the recurrence of pancreatitis after Adalimumab rechallenge. The occurrence of acute pancreatitis induced by TNFα inhibitors exposes to the risk of pancreatitis with other drugs in this class, hence the need to switch to another therapeutic class, which was Ustekinumab in our case.Conclusion: Acute pancreatitis is an unusual complication of treatment with Adalimumab. Through our experience, based on solid scientific data, we want to draw the attention of clinicians to the reality of this complication. It should be considered in any patient on TNFα inhibitors who presents with acute pancreatitis without an obvious cause.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251315000"},"PeriodicalIF":0.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaping: A Safe Alternative to Counteract Smoking? Case Report. 电子烟：一种安全的替代吸烟？病例报告。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-01-16 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251313766

María Cristina Martínez-Ávila, Eugenio Matijasevic Ardila, Alieth Lucía Acosta Cardozo, Cristian Camilo Alvarado Castro, Carlos Eduardo Matiz-Bueno

引用次数: 0

Immune-Complex Mediated Mesangial Proliferative Glomerulonephritis with Full-House Pattern Observed During Treatment of Immune Thrombocytopenic Purpura. 免疫复合物介导的系膜增生性肾小球肾炎伴全屋型在免疫性血小板减少性紫癜治疗期间的观察。

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Clinical Medicine Insights. Case Reports Pub Date : 2024-12-24 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241307123

Ai Ueki, Tsugumi Fukunaga, Hiroyasu Goto, Hitoshi Minakuchi, Naoki Oshima

{"title":"Immune-Complex Mediated Mesangial Proliferative Glomerulonephritis with Full-House Pattern Observed During Treatment of Immune Thrombocytopenic Purpura.","authors":"Ai Ueki, Tsugumi Fukunaga, Hiroyasu Goto, Hitoshi Minakuchi, Naoki Oshima","doi":"10.1177/11795476241307123","DOIUrl":"10.1177/11795476241307123","url":null,"abstract":"This study reports a rare case of immune-complex mediated mesangial proliferative glomerulonephritis (ICGN) with a full-house pattern in a 56-year-old Japanese man, observed during the treatment of immune thrombocytopenic purpura (ITP). Because of persistent complement deficiency and worsening of kidney function, he was treated with prednisolone, and his urinary findings improved markedly. However, as the complement titers were still low, mycophenolate mofetil was also prescribed, which normalized complement levels. Production of anti-platelet antibodies is considered to be involved in the etiology of ITP. Although little is known about the mechanism by which ITP causes glomerulonephritis, including ICGN, glomerular deposition of circulating immune complexes synthesized by antiplatelet antibodies may be involved. This case shows full-house nephropathy, suggesting the involvement of immune complexes, which in turn, suggested an association between ITP and glomerulonephritis.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241307123"},"PeriodicalIF":0.8,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11672467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Unusual Diagnosis of Rectosigmoid Leiomyoma in an Adult: A Rare Case Report. 成人直肠乙状结肠平滑肌瘤的罕见诊断：一罕见病例报告。

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Clinical Medicine Insights. Case Reports Pub Date : 2024-12-20 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241307592

Karam Karam, Houssein Chebbo, Sarah Saleh, Sarah Jalloul, Johny Salem, Karim Al Halabi, Elias Fiani

引用次数: 0

Pregnancy-Related Morphea: A Case Report. 妊娠性睡眠：一例报告。

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Clinical Medicine Insights. Case Reports Pub Date : 2024-12-18 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241302563

Sedigheh Borna, Zeynab Zamanpour, Safoura Shakoei, Maryam Aliasgharpoor, Zahra Hamidi Madani

{"title":"Pregnancy-Related Morphea: A Case Report.","authors":"Sedigheh Borna, Zeynab Zamanpour, Safoura Shakoei, Maryam Aliasgharpoor, Zahra Hamidi Madani","doi":"10.1177/11795476241302563","DOIUrl":"10.1177/11795476241302563","url":null,"abstract":"Background: Morphea is a skin condition marked by erythematous and hardened inflammatory lesions that can progress to atrophic and sclerotic plaques. In this case report, we present a case of a pregnant woman who showed morphea presentation.Case presentation: A 37-year-old G2P1L1 woman with a gestational age of 32 weeks and 2 days was referred to the hospital with complaints of swelling, pain, and erythema in both legs for the past week, without any obstetric complaints. Upon initial examination at the time of admission, swelling, erythema, warmth in both legs, ecchymotic lesions, and non-pitting edema were observed. Biometry and color Doppler ultrasound for evaluation of fetus growth was normal. Skin examination revealed mild erythema, warmth, and purpura and petechiae in some areas, with an orange peel appearance and firm texture on palpation. Leg lesion skin punch biopsy reported a sclerodermoid reaction pattern and findings more compatible with morphea. The patient was managed for morphea during pregnancy. However, at 38 weeks and 6 days of gestation, due to worsening symptoms and spreading stiffness to the groin area, and the need for initiating pulse corticosteroids and mycophenolate mofetil (CellCept), the patient was re-admitted for cesarean section. In the follow-up assessment, ultrasound findings were normal, IGRA, HIV antibody, HCV antibody, HBC antigen, and HBS antigen were negative, and no edema or inflammation was seen in the patient.Conclusions: In conclusion, although our patient recovered without specific treatment, predicting the recurrence or worsening of morphea in future pregnancies is challenging.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241302563"},"PeriodicalIF":0.8,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ewing Sarcoma of Left Thigh With Nodal, Paraspinal and Soft Tissue Metastatic Lesions: A Case Report. 左腿尤文氏肉瘤伴淋巴结、棘旁及软组织转移1例。

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Clinical Medicine Insights. Case Reports Pub Date : 2024-11-28 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241302545

Radeyah Waseem, Muskan Seher, Sohiba Ghazal, Edrees Khan, Hussain Haider Shah, Muhammad Sheheryar Hussain

{"title":"Ewing Sarcoma of Left Thigh With Nodal, Paraspinal and Soft Tissue Metastatic Lesions: A Case Report.","authors":"Radeyah Waseem, Muskan Seher, Sohiba Ghazal, Edrees Khan, Hussain Haider Shah, Muhammad Sheheryar Hussain","doi":"10.1177/11795476241302545","DOIUrl":"10.1177/11795476241302545","url":null,"abstract":"Introduction: Ewing sarcoma is a rare and highly aggressive malignancy, mostly involving the axial skeleton. Ewing sarcoma usually affects children and young adults under 20. Usually presenting as a painful swelling and discomfort worsening over time.Case report: We present a case of a 19-year-old female with no known co-morbidities presenting in the Emergency Department with complaints of fever and backache for the past 2 weeks and bilateral lower limb weakness for more than a week. She was started on steroids and broad-spectrum antibiotics and packed cell volume due to low hemoglobin. The screening MRI of the cervical and dorsal spine without contrast revealed signal abnormalities in the vertebral bodies at multiple levels (C2, C5, C6, C7, T1, and T3), as well as within the spinous processes and interspinous musculature. Further evaluation with contrast-enhanced MRI was recommended. The contrast-enhanced MRI showed straightening of the cervical and dorsal spine due to muscular spasm. Additionally, there were small soft tissue components in the left paravertebral region at the level of D3, extending into the epidural space, and epidural components encasing the thecal sac at the levels of D5, D9, and D10 suggestive of neoplastic lesions, most likely metastasis. The morphological and immunohistochemical correlation established the diagnosis of Ewing Sarcoma of the left thigh with nodal, para-spinal, and soft tissue metastatic lesions.Conclusion: Ewing Sarcoma is generally reported in the pediatric population and may come into clinical view based on a plethora of signs and symptoms. Appropriate imaging in the form of X-rays, CT scans, and MRI must be employed to correctly diagnose, and stage the condition.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241302545"},"PeriodicalIF":0.8,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intra-Parotid Recurrent Nasopharyngeal Carcinoma Following Intensity-Modulated Radiation Therapy: A Case Report. 调强放射治疗后腮腺内复发性鼻咽癌：病例报告。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-11-07 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241295723

Abderrahim Bourial, Othmane Nourallah Laraqui, Chirwa Abdillahi Mahamoud, Hiba Elhani, Reyzane Elmjabber, Loubna Taali, Said Anajar, Mustapha Essaadi, Khalid Snoussi, Zineb Dahbi, Amal Hajjij

{"title":"Intra-Parotid Recurrent Nasopharyngeal Carcinoma Following Intensity-Modulated Radiation Therapy: A Case Report.","authors":"Abderrahim Bourial, Othmane Nourallah Laraqui, Chirwa Abdillahi Mahamoud, Hiba Elhani, Reyzane Elmjabber, Loubna Taali, Said Anajar, Mustapha Essaadi, Khalid Snoussi, Zineb Dahbi, Amal Hajjij","doi":"10.1177/11795476241295723","DOIUrl":"https://doi.org/10.1177/11795476241295723","url":null,"abstract":"Introduction: Intra-parotid metastasis refers to the spread of cancerous cells from a primary tumor to the lymph nodes within the parotid gland. To our best knowledge, we report the first described case in the literature of a patient who received IMRT for nasopharyngeal carcinoma (UCNT) without sparing the parotid gland and still experienced a recurrence.Case presentation: A 57-year-old male patient of north African origin presented with a left parotid mass that had been evolving for 6 months. He was previously diagnosed with and treated for nasopharyngeal carcinoma 2 years prior to admission, with Intensity-Modulated Radiotherapy (IMRT) without sparing the parotid gland, as well as chemotherapy. Medical imaging was suggestive of recurrence of nasopharyngeal carcinoma and metastasis due to the patient's medical history. The patient benefited from a total parotidectomy; The histopathological analysis of the surgical specimen confirmed the presence of a poorly differentiated carcinoma (UCNT) with nodal metastasis.Conclusion: Intensity-Modulated Radiation Therapy (IMRT) holds great promise as an alternative treatment option. However, it should be reserved for specific cases with minimal lymph node involvement, and always preceded by a thorough clinical and radiological examination.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241295723"},"PeriodicalIF":0.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed Diagnosis of Constrictive Pericarditis Resulting in Recurrent Heart Failure: A Case Report. 缩窄性心包炎诊断延误导致复发性心力衰竭：病例报告

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-10-27 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241295725

Chunliang Wang, Yuzhu Fan, Guiting Liang, Yu Chen, Tian Tu, Juan Du

引用次数: 0

Electrocoagulation Therapy for Urethral Condyloma Acuminata in a Male Patient: Case Report. 电凝疗法治疗男性尿道尖锐湿疣：病例报告。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-10-18 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241292903

Ghassane El Omri, Hamza Rais, Anas Taghouan, Moussaab Rachid, Younes Houry, Abdeljalil Heddat

{"title":"Electrocoagulation Therapy for Urethral Condyloma Acuminata in a Male Patient: Case Report.","authors":"Ghassane El Omri, Hamza Rais, Anas Taghouan, Moussaab Rachid, Younes Houry, Abdeljalil Heddat","doi":"10.1177/11795476241292903","DOIUrl":"10.1177/11795476241292903","url":null,"abstract":"Condyloma acuminata (CA) is a common manifestation of human papillomavirus (HPV) infection affecting the urogenital tract. While external genital lesions are frequently encountered, urethral involvement presents a therapeutic challenge due to the risk of recurrence and long-term complications such as urethral stricture. We present a case of urethral condyloma acuminata in a 43-year-old male patient who demonstrated favorable progression following electrocoagulation therapy. The patient presented with urethrorrhagia and lower urinary tract symptoms, with subsequent diagnosis confirmed via urological examination. Negative results from extensive microbiological testing supported the diagnosis. Treatment involved biopsy excision combined with electrocoagulation, resulting in complete resolution of symptoms without recurrence at 2-month follow-up. This case underscores the importance of individualized treatment strategies for intraurethral condyloma acuminata and highlights electrocoagulation therapy as a viable option with favorable outcomes.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241292903"},"PeriodicalIF":0.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11490944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0