Clinical Medicine Insights. Case Reports最新文献

Crusted Scabies in a Malnourished Patient: A Rare Case Report.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-03-19 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251326462

Lina Al-Soufi, Aya Marashli, Mohammad Adi, Zuheir Al-Shehabi

{"title":"Crusted Scabies in a Malnourished Patient: A Rare Case Report.","authors":"Lina Al-Soufi, Aya Marashli, Mohammad Adi, Zuheir Al-Shehabi","doi":"10.1177/11795476251326462","DOIUrl":"10.1177/11795476251326462","url":null,"abstract":"Introduction: Scabies is a parasitic skin condition, with crusted scabies (CS) being a severe and highly contagious variant characterized by thickened skin lesions and a high mite count. CS is typically associated with immunocompromised individuals but can also develop in those suffering from malnutrition, as malnutrition weakens immune responses and impairs skin integrity.Case presentation: We report a case of CS in a 50-year-old malnourished male with no history of scabies or systemic disease, recently incarcerated. He presented with widespread itching, hyperkeratotic papules on the palms and soles, and secondary impetigo. The patient showed signs of malnutrition, with a BMI of 15.6 kg/m² and muscle wasting. Sarcoptes scabiei mites, eggs, and scybala were identified microscopically. The case was classified as Grade 3 CS. Treatment included two doses of ivermectin (8 mg) one week apart, 10% sulfur ointment, and benzyl benzoate soap. Follow-up was incomplete, highlighting challenges in managing socially vulnerable patients.Discussion: This case emphasizes the importance of early recognition, accurate diagnosis, and effective treatment of CS, especially in settings with poor sanitation and overcrowding. The patient's malnutrition likely contributed to the severity of the condition, as compromised immunity can facilitate mite proliferation.Conclusion: A holistic approach addressing malnutrition, sanitation, and patient education is crucial in managing CS in resource-limited settings.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251326462"},"PeriodicalIF":0.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Exceptional Case of a Supra-tentorial Streptococcus Salivarius Brain Abscess-A Case Report.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-03-18 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251325803

Abderrahim Bourial, Wahib Lahlou, Mounir Rghioui, Sidi Mamoun Louraoui, Abdessamad El Azhari, Fadila Guessous

{"title":"An Exceptional Case of a Supra-tentorial Streptococcus Salivarius Brain Abscess-A Case Report.","authors":"Abderrahim Bourial, Wahib Lahlou, Mounir Rghioui, Sidi Mamoun Louraoui, Abdessamad El Azhari, Fadila Guessous","doi":"10.1177/11795476251325803","DOIUrl":"10.1177/11795476251325803","url":null,"abstract":"Introduction: During the COVID-19 pandemic, incidence of brain abscesses is difficult to assess. Numerous studies reported benign and severe post SARS-CoV-2 vaccine side effects, including rare cases of brain abscesses associated with COVID-19 or Anti-SARS-CoV-2 vaccines. Here in, we report what we believe to be, up to date, the fourth known case in the medical literature of a streptococcus salivarius brain abscess, the first intra parenchymatous or supra-tentorial streptococcus salivarius brain abscess and also the first that occurs following an anti-SARS-CoV-2 vaccine.Case presentation: We describe the case of a north african 63-year-old man with an unremarkable medical history except for recent anti-SARS-CoV-2 vaccinations. Following the administration of a third anti-SARS-CoV-2 booster vaccine, the patient developed neurological symptoms, including left hemiparesis, facial palsy, vertigo, and balance issues. Imaging studies revealed a right temporo-parietal lesion consistent with intracranial suppuration. Stereotaxic cerebral biopsy confirmed the presence of purulent content, indicating a brain abscess caused by multi-sensitive streptococcus salivarius.Conclusion: Sepsis-induced immunodepression appears to be a consequence of severe inflammatory state, as it dysregulates leukocytes population and results in serious infections. A plausible hypothesis is that a previous stress such as anti-SARS-CoV-2 vaccination could lead to the development of a streptococcus salivarius septicemia. In light of the available evidence and research findings, no definitive conclusion can be drawn regarding any potential link between anti-SARS-CoV-2 vaccines and the physiopathology of sepsis-induced immunodepression.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251325803"},"PeriodicalIF":0.8,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Poorly Cohesive Carcinoma of Common Bile Duct: A Rare Histological Type of Cholangiocarcinoma.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-03-16 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251324361

Derqaoui Sabrine, Hamid Mohamed, Ahmed Jahid, Kaoutar Znati, Fouad Zouaidia, Settaf Abdellatif, Bernoussi Zakiya

引用次数: 0

Spontaneous Coronary Artery Dissection-Different Faces of the Same Disease.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251322433

Kinga Kowalik, Małgorzata Wojciechowska, Karol Momot, Izabela Poprawa, Maciej Dąbrowski, Mariusz Kruk, Maciej Zarębiński

引用次数: 0

Ewing Sarcoma Presenting as Fever of Unknown Origin (FUO) in Children: A Case Report and Brief Review of the Literature.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-02-26 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251323164

Hasan Arafat, Zahraa Mm Zeer, Almotazbellah Mm Zeer, Mahmoud Noman, Hamza A Abdul-Hafez, Ahmad G Hammouri, Amer Zughayyer

引用次数: 0

Diagnosis and Management of Tuberous Sclerosis Complex in a Resource-Limited Setting-A Case Report of a 14-Year-Old Female Zambian Adolescent.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251321268

Mwamba Lienda, Meek Mwila, Chilala Sichula, Chishiba Kabengele, Moses Akombwa, Christina Zulu, Chihena Hansini Banda, Hellen M'hango

{"title":"Diagnosis and Management of Tuberous Sclerosis Complex in a Resource-Limited Setting-A Case Report of a 14-Year-Old Female Zambian Adolescent.","authors":"Mwamba Lienda, Meek Mwila, Chilala Sichula, Chishiba Kabengele, Moses Akombwa, Christina Zulu, Chihena Hansini Banda, Hellen M'hango","doi":"10.1177/11795476251321268","DOIUrl":"10.1177/11795476251321268","url":null,"abstract":"Tuberous sclerosis complex (TSC) is a rare multisystemic neurocutaneous syndrome with a wide spectrum of clinical manifestations. We present a case of a 14-year-old adolescent female who presented with a history of facial angiofibromas since the age of 8 months. Physical examination was remarkable for multiple angiofibromas on the face, and other multiple cutaneous manifestations of TSC. MRI of the head, and abdomen revealed cortical tubers, multiple bilateral periventricular and subependymal nodular lesions, calcifications, and bilateral kidney enlargement with multiple bilateral renal angiomyolipomas of varying sizes in a background of bilateral polycystic kidneys, MRI of the chest was unremarkable. A diagnosis of TSC was made using the clinical diagnostic criteria which consist of major and minor features. A diagnosis using genetic studies could not be made due to a lack of resources. Management was multidisciplinary and regular monitoring every 6 months will be required to monitor disease progression and manage complications as they arise. This case illustrates the multidisciplinary approach needed to address the diverse clinical manifestations of TSC and the diagnostic challenges, treatment limitations, and psychological impact of TSC in low-resource settings like Zambia where access to advanced therapies is limited.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251321268"},"PeriodicalIF":0.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Presentation of Chronic Exfoliative Cheilitis: Case Report.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251319981

Abdelrahman Eltoureini, Hamad Alharbi, Wafaa Saleh

{"title":"A Rare Presentation of Chronic Exfoliative Cheilitis: Case Report.","authors":"Abdelrahman Eltoureini, Hamad Alharbi, Wafaa Saleh","doi":"10.1177/11795476251319981","DOIUrl":"10.1177/11795476251319981","url":null,"abstract":"Background: Chronic exfoliative cheilitis is an inflammatory condition of the lips that involves exfoliation of the superficial layers of the lip with continuous peeling, ulceration, and exfoliation. Chronic exfoliative cheilitis can lead to social and psychosocial problems.Case presentation: A 73-year-old diabetic male presented with a lip lesion showing continuous ulceration, crusting, and peeling of the lower lip. It was a spontaneous complaint that had its onset 6 months ago and has constantly evolved. The medical history revealed controlled diabetes mellitus while the social and family histories showed no marked findings. After a careful history, clinical examination, and laboratory investigations with the exclusion of the possible etiologic factors of cheilitis, the patient was diagnosed with chronic exfoliative cheilitis with unknown etiology. Then, the patient was prescribed topical steroids, and he was advised for continuous follow-up visits.Conclusion: Diagnosing chronic cheilitis is challenging and requires careful history, clinical examination, and laboratory investigation, with continuous follow-up to improve the patient's quality of life. Further research is needed to better understand and treat these cases.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251319981"},"PeriodicalIF":0.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin D Deficiency-Induced Proximal Myopathy in a Pediatric Patient During COVID-19 Lockdown: A Case Report.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251320006

Mohammad Hazique, Arihant Surana, Aashna Mehta, Helen Huang, Surour Alneyadi, Kavita Shah, Ajeet Singh, Amit Varma, Mahendra Pratap Singh, Sanjit Sah, Amogh Verma

{"title":"Vitamin D Deficiency-Induced Proximal Myopathy in a Pediatric Patient During COVID-19 Lockdown: A Case Report.","authors":"Mohammad Hazique, Arihant Surana, Aashna Mehta, Helen Huang, Surour Alneyadi, Kavita Shah, Ajeet Singh, Amit Varma, Mahendra Pratap Singh, Sanjit Sah, Amogh Verma","doi":"10.1177/11795476251320006","DOIUrl":"10.1177/11795476251320006","url":null,"abstract":"Vitamin D deficiency is a significant public health concern that affects bone health and muscle function in children, especially in developing countries. The COVID-19 pandemic has intensified this issue because lockdowns have reduced sunlight exposure. We report a rare case of a 13-year-old Indian boy who developed severe proximal myopathy induced by vitamin D deficiency during the pandemic. The patient presented with generalized body aches, progressive lower limb weakness, difficulty walking, waddling gait, and a positive Gower's sign. Laboratory tests revealed severe hypovitaminosis D (25[OH]D level, 3.8 ng/ml), hypocalcemia, hypophosphatemia, elevated parathyroid hormone, and elevated alkaline phosphatase levels. Electromyography and nerve conduction study results were normal. The patient was diagnosed with vitamin D deficiency-induced proximal myopathy and osteomalacia, likely due to reduced sunlight exposure, inadequate dietary intake, and obesity. The treatment involved high-dose vitamin D supplementation, oral calcium, lifestyle modifications, and a structured physiotherapy program focusing on resistance training and functional mobility exercises. Despite biochemical normalization after 2 months, significant symptomatic improvement was achieved only after intensifying physiotherapy. By 7 months, the patient had fully recovered muscle strength, achieved normal gait, and maintained normal follow-up laboratory values. This case emphasizes the importance of considering vitamin D deficiency in children with muscle weakness during periods of limited sunlight exposure, and highlights the need for a multidisciplinary approach for effective management and full functional recovery.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251320006"},"PeriodicalIF":0.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ascaris lumbricoides Emerging from a PleurX Draining Catheter: An Unexpected Diagnosis.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-01-28 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251315619

Hasan Arafat, Hamza A Abdul-Hafez, Ali Sabateen

引用次数: 0

Acute Pancreatitis: An Unusual Side Effect of Adalimumab in Crohn's Disease Patient.

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI: 10.1177/11795476251315000

Walid El Ouardi, Mustapha Benazzouz

{"title":"Acute Pancreatitis: An Unusual Side Effect of Adalimumab in Crohn's Disease Patient.","authors":"Walid El Ouardi, Mustapha Benazzouz","doi":"10.1177/11795476251315000","DOIUrl":"10.1177/11795476251315000","url":null,"abstract":"Background: Drug-induced acute pancreatitis is a rare condition occurs at an incidence rate of 0.1-1.4% and represents a diagnostic challenge. TNFα inhibitors specially adalimumab is very rarely reported in the literature, primarily through case reports, as a potential cause of acute pancreatitis.Case presentation: Our case report presents a case of a 23-year-old patient followed for Crohn disease in whom a diagnosis of acute pancreatitis induced by adalimumab was made. This diagnosis was confirmed after the elimination of other possible etiologies, and notably by the recurrence of pancreatitis after Adalimumab rechallenge. The occurrence of acute pancreatitis induced by TNFα inhibitors exposes to the risk of pancreatitis with other drugs in this class, hence the need to switch to another therapeutic class, which was Ustekinumab in our case.Conclusion: Acute pancreatitis is an unusual complication of treatment with Adalimumab. Through our experience, based on solid scientific data, we want to draw the attention of clinicians to the reality of this complication. It should be considered in any patient on TNFα inhibitors who presents with acute pancreatitis without an obvious cause.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"18 ","pages":"11795476251315000"},"PeriodicalIF":0.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0