Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report.

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL

Clinical Medicine Insights. Case Reports Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI:10.1177/11795476251345877

Sumanth Gundraju, Jaideep Menda, Tarun Kumar Suvvari, Anupama Kumudavalli Pindi, Prudhvi Kumar Davala, Tejinder Singh, Vimal Thomas

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Abstract

Chorea Hyperglycemia Basal Ganglia Syndrome (CHBG) is an uncommon neurological complication arising in diabetic patients with severe, non-ketotic hyperglycemia. This case report describes a 50-year-old woman presenting with new-onset, choreiform movements in her extremities. Initial workup revealed uncontrolled diabetes (plasma glucose 410 mg/dl, HbA1c 11.2%) with negative serum ketones. Brain MRI findings supported the diagnosis, demonstrating characteristic T1 hyperintensity in the right basal ganglia. Implementation of gradual glycemic control over 48 hours led to significant improvement of her symptoms. This case emphasizes the importance of considering CHBG in the differential diagnosis of movement disorders in patients with uncontrolled diabetes. Early recognition and prompt glycemic management can lead to complete resolution of symptoms, highlighting the crucial role of maintaining proper blood sugar control in diabetic patients.

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血糖控制逆转舞蹈病高血糖基底神经节综合征1例报告。

高血糖舞蹈病基底神经节综合征（CHBG）是一种罕见的神经系统并发症，出现在糖尿病患者严重的，非酮症高血糖。本病例报告描述了一名50岁的女性，她的四肢出现了新发的舞蹈动作。初步检查显示糖尿病未控制（血糖410 mg/dl，糖化血红蛋白11.2%），血清酮阴性。脑部MRI结果支持诊断，显示右侧基底节特征性T1高强度。在48小时内实施渐进式血糖控制使她的症状显著改善。本病例强调了在未控制的糖尿病患者的运动障碍鉴别诊断中考虑CHBG的重要性。早期识别和及时的血糖管理可以导致症状的完全解决，强调了维持适当的血糖控制在糖尿病患者中的关键作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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