Case Reports in Ophthalmology最新文献_第5页

Presumed Choroidal Metastasis of Primary Cutaneous Melanoma: A Case Report. 原发性皮肤黑色素瘤的脉络膜转移：1例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI: 10.1159/000544879

Teele Palumaa, Artur Klett

{"title":"Presumed Choroidal Metastasis of Primary Cutaneous Melanoma: A Case Report.","authors":"Teele Palumaa, Artur Klett","doi":"10.1159/000544879","DOIUrl":"https://doi.org/10.1159/000544879","url":null,"abstract":"Introduction: Choroidal metastases most often originate from breast tumors in females and lung cancer in males. Primary cutaneous tumors rarely metastasize to the uveal tract.Case presentation: Here, we present a rare case of a 47-year-old female patient who was clinically diagnosed with a presumed choroidal metastasis of primary cutaneous melanoma. The patient presented with complaints of decreased vision in her right eye. Her best corrected visual acuity (BCVA) was 0.7 decimal in the right eye and 1.0 in the left eye. Examination revealed a pigmented choroidal lesion in the parafoveal region with a prominence of 2.9 mm, orange pigment on the surface, and subretinal fluid in its projection. She had no history of active malignancy, but at the age of 36, a localized stage IB cutaneous melanoma was removed from her back. Yearly follow-up visits at the dermatologist showed no evidence of active disease. Upon diagnosis of a choroidal tumor, the patient underwent brachytherapy with a ruthenium-106 plaque in the right eye. Follow-up at the oncologist revealed a widespread disease with metastases in distant lymph nodes, liver, lung, pancreas, and brain, an uncommon pattern for primary choroidal melanomas, resembling rather the metastasis pattern of primary cutaneous melanoma. The patient was started on systemic therapy against metastatic cutaneous melanoma. At 21 months after brachytherapy and 19 months after the initiation of systemic anticancer therapy, the patient's BCVA in the right eye returned to 1.0 decimal, the choroidal lesion reduced in size, and subretinal fluid receded. Two years after the initial presentation, all metastases were stable or decreased in size.Conclusion: This case highlights the possibility of a choroidal metastasis of cutaneous melanoma more than a decade after the first presentation of the disease and highlights the effectiveness of combined brachytherapy and systemic anticancer therapy in managing the disease.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"267-273"},"PeriodicalIF":0.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12002729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orbital Fracture Resulting in Contralateral Optic Canal Fracture with Traumatic Optic Neuropathy: A Case Report. 眼眶骨折致对侧视神经管骨折伴外伤性视神经病变1例。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-20 eCollection Date: 2025-01-01 DOI: 10.1159/000545040

Paulina Truong, Saif Aldeen Alryalat, Osama Al Deyabat, Amina Malik, Masayoshi Takashima, Andrew Go Lee

{"title":"Orbital Fracture Resulting in Contralateral Optic Canal Fracture with Traumatic Optic Neuropathy: A Case Report.","authors":"Paulina Truong, Saif Aldeen Alryalat, Osama Al Deyabat, Amina Malik, Masayoshi Takashima, Andrew Go Lee","doi":"10.1159/000545040","DOIUrl":"https://doi.org/10.1159/000545040","url":null,"abstract":"Introduction: Traumatic optic neuropathy (TON) can cause acute vision loss after head trauma, either due to indirect shearing forces or direct trauma, i.e., by a bony fragment of an optic canal fracture (OCF). We present a case of TON due to an isolated OCF with contralateral orbital fracture and injury.Case presentation: A 19-year old male presented with immediate total loss of vision to no light perception in the right eye after being struck on the left cheek by a lawn sign. Computed tomography and magnetic resonance imaging revealed left orbital floor fracture and right optic nerve enhancement. The patient was treated with high-dose intravenous corticosteroids and plasma exchange for a presumed inflammatory or TON. Repeat orbital imaging revealed a right OCF with bony impingement of the optic nerve. The patient underwent endoscopic optic nerve decompression; a 4 × 5 mm bone fragment abutting the optic nerve was removed. 1 month later, vision improved to hand motion.Conclusion: Imaging may fail to detect OCF, and visual prognosis depends on time to surgery and fracture pattern. Therefore, operative management and preoperative intravenous corticosteroids, though controversial, may be considered even in the absence of radiographic findings of bony impingement causing direct TON. Isolated OCF without continuous fractures originating at the injury site is also a rare fracture pattern and potential cause of direct TON.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"290-296"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fovea Sparing Branch Retinal Artery Occlusions Imaged with Optical Coherence Tomography Angiography: Two Case Reports. 光学相干断层扫描血管造影显示视网膜中央凹保留分支动脉闭塞：2例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.1159/000543742

Benjamin R Lin, Philip J Rosenfeld, Harry W Flynn

{"title":"Fovea Sparing Branch Retinal Artery Occlusions Imaged with Optical Coherence Tomography Angiography: Two Case Reports.","authors":"Benjamin R Lin, Philip J Rosenfeld, Harry W Flynn","doi":"10.1159/000543742","DOIUrl":"https://doi.org/10.1159/000543742","url":null,"abstract":"Introduction: Central retinal artery occlusions and branch retinal artery occlusions (BRAOs) are ophthalmic emergencies that require workups for systemic risk factors. In the acute setting, BRAOs present with retinal whitening in a sectoral pattern on exam as well as hyperreflectivity and thickening of the inner retinal layers on optical coherence tomography (OCT). In the subacute to chronic phase, the retinal whitening dissipates, which may confound the diagnosis of remote arterial occlusions if there is no clearly visible plaque.Case presentations: A 66-year-old male presented with 20/25 visual acuity (VA) and an inferior visual field defect in the right eye, and a 69-year-old male presented with 20/60 VA and a superior visual field defect in the left eye. Exams of both patients showed ischemic retinal whitening with visible Hollenhorst plaques in the affected eyes. OCT demonstrated inner retinal edema. At follow-up, wide-field OCT angiography (OCTA) showed persistent capillary dropout following the same initial vascular distribution but sparing the fovea and papillomacular bundle. VAs at the most recent follow-up visits were 20/30 and 20/20, respectively.Conclusion: These cases demonstrate the utility of wide-field OCTA in characterizing areas of capillary nonperfusion that can persist for years after the initial ischemic event. Additionally, patients with macula-involving BRAOs can have good VA outcomes if the fovea is spared.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"274-280"},"PeriodicalIF":0.5,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12005688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Topical Losartan Treatment of Herpes Simplex Virus- or Varicella-Zoster Virus-Induced Corneal Scarring: A Case Series. 局部氯沙坦治疗单纯疱疹病毒或水痘带状疱疹病毒引起的角膜瘢痕：病例系列

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-11 eCollection Date: 2025-01-01 DOI: 10.1159/000545215

Barbara A L Dutra, Laura E Drew-Bear, Samantha P Herretes, Danielle Arroyo, Rodrigo Carlos de Oliveira, Lycia Pedral Sampaio, Marcony R Santhiago, Steven E Wilson

{"title":"Topical Losartan Treatment of Herpes Simplex Virus- or Varicella-Zoster Virus-Induced Corneal Scarring: A Case Series.","authors":"Barbara A L Dutra, Laura E Drew-Bear, Samantha P Herretes, Danielle Arroyo, Rodrigo Carlos de Oliveira, Lycia Pedral Sampaio, Marcony R Santhiago, Steven E Wilson","doi":"10.1159/000545215","DOIUrl":"https://doi.org/10.1159/000545215","url":null,"abstract":"Introduction: Topical losartan has emerged as a promising therapeutic option for preventing and treating corneal scarring fibrosis. Its mechanism of action involves the inhibition of ERK-mediated signaling in the noncanonical TGF-beta pathways, promoting apoptosis of myofibroblasts and facilitating a return of corneal transparency. While numerous studies in rabbits and several human case reports have demonstrated its efficacy and safety, published data on its use in clinical scenarios remain limited. This study presents 3 cases where topical losartan successfully treated corneal scarring induced by herpes simplex virus (HSV) or varicella-zoster virus (VZV) keratitis.Case presentations: Three patients (ages 40, 38, 15 years) with corneal scarring and vision loss from HSV or VZV keratitis were treated with topical 0.8 mg/mL losartan 6 times a day for 4-9 months, depending on the clinical response, after failing traditional management with corticosteroids. Best spectacle-corrected vision and slit-lamp corneal opacity improved in each case. Anterior segment OCT documented improved stromal opacity in 1 case.Conclusions: Topical losartan, a known inhibitor of fibrotic TGF-beta signaling, is potentially an effective alternative in the treatment of stromal scarring fibrosis caused by corneal HSV and VZV infections. Patients with HSV- or VZV keratitis-induced corneal scarring may be ideal candidates for planned clinical trials of the efficacy and safety of topical losartan treatment.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"281-289"},"PeriodicalIF":0.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12005691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Subretinal Hemorrhage in a Patient Taking a Turmeric Supplement: Case Report. 服用姜黄补充剂的患者复发性视网膜下出血：病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-10 eCollection Date: 2025-01-01 DOI: 10.1159/000545076

Sherry Narang Kalla

{"title":"Recurrent Subretinal Hemorrhage in a Patient Taking a Turmeric Supplement: Case Report.","authors":"Sherry Narang Kalla","doi":"10.1159/000545076","DOIUrl":"https://doi.org/10.1159/000545076","url":null,"abstract":"Introduction: This case report highlights the importance of knowing what nonprescription medications and supplements are being taken by patients in addition to their prescribed medications.Case presentation: A 48-year-old myopic male presented with a 1-day history of hand motion vision. He was found to have an extensive vitreous hemorrhage with no view of the fundus. On follow-up 4 days later, he continued to have a significant vitreous hemorrhage and a B scan that showed a possible retinal tear. Upon having surgery 7 days later, he was found to have a temporal retinal detachment with subretinal fluid and hemorrhage extending to, but not involving, the macula. His postoperative course was complicated by persistent preretinal and subretinal hemorrhages along with recurrent retinal detachments requiring 2 additional surgeries. He was evaluated by his primary care physician and had a normal thrombotic work-up and all his dietary supplements, including turmeric, were discontinued. At post-op month 2, he continued to improve with resolving subretinal hemorrhage and an attached retina.Conclusion: This case report describes the extensive and recurrent subretinal hemorrhage that can develop in those patients taking medications or supplements with anticoagulant and/or antiplatelet properties. These antithrombotic agents are not only limited to prescription medications but can also include dietary supplements such as turmeric. It highlights the importance of knowing both the medications and dietary supplements a patient uses as this can affect the long-term outcome.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"297-301"},"PeriodicalIF":0.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12028978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ipsilateral, Multi-Phasic Retinal Vascular Events following Intralesional Triamcinolone Acetonide Injection for Earlobe Keloid: A Case Report. 耳垂瘢痕疙瘩病灶内注射曲安奈德后发生同侧多相视网膜血管事件1例。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-08 eCollection Date: 2025-01-01 DOI: 10.1159/000543454

Yafeng Li

{"title":"Ipsilateral, Multi-Phasic Retinal Vascular Events following Intralesional Triamcinolone Acetonide Injection for Earlobe Keloid: A Case Report.","authors":"Yafeng Li","doi":"10.1159/000543454","DOIUrl":"10.1159/000543454","url":null,"abstract":"Introduction: Intralesional triamcinolone acetonide is a widely used treatment for scarring skin conditions such as keloid and is known to have retinal vascular complications if administered in the periocular region.Case presentation: A 32-year-old female experienced a prompt onset transient vision decrease and a delayed onset, slow-resolving vison loss in the right eye (OD) following the last of a series of triamcinolone acetonide corticosteroid (TAC) injections in her right earlobe for a disfiguring keloid. Clinically, she developed a branch retinal arterial occlusion accompanied by features of a central retinal vein occlusion. The TAC particles that entered the retinal circulation are implicated in the thrombo-embolic occlusion of the branch retinal artery and subsequent blockage of the central retinal vein.Conclusion: This case should alert clinicians that there is always a potential hazard for retinal vascular occlusion when corticosteroid is injected in the region of the head and face because of the rich anastomoses between the external and internal carotid artery circulations.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"254-260"},"PeriodicalIF":0.5,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DNAJC30 Mutation in a Patient with Coexisting Leber's Hereditary Optic Neuropathy and Multiple Sclerosis (Harding's Syndrome): A Case Report. 合并Leber遗传性视神经病变和多发性硬化症（哈丁综合征）患者的DNAJC30突变：1例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-07 eCollection Date: 2025-01-01 DOI: 10.1159/000545079

Sara KamaliZonouzi, Jonathan Micieli

{"title":"DNAJC30 Mutation in a Patient with Coexisting Leber's Hereditary Optic Neuropathy and Multiple Sclerosis (Harding's Syndrome): A Case Report.","authors":"Sara KamaliZonouzi, Jonathan Micieli","doi":"10.1159/000545079","DOIUrl":"10.1159/000545079","url":null,"abstract":"Introduction: Patients with Leber's hereditary optic neuropathy (LHON) have a higher risk of developing multiple sclerosis (MS) than the general population. The coexistence of LHON and MS, also known as Harding's syndrome complicates the diagnosis of optic neuropathy, particularly when the underlying genetic mutation is a rare cause of LHON like DNAJC30.Case presentation: We present a 26-year-old woman with progressive, sequential, painless, bilateral visual loss which was unresponsive to steroids, and two temporally distinct episodes of neurological disturbance suggestive of central nervous system demyelination. Thorough investigations including serological tests ruled out other causes, including negative neuromyelitis optica and myelin oligodendrocyte protein (MOG) antibodies and nutritional deficiencies. MRI detected areas of demyelination within the spinal cord and brain (infratentorial and periventricular areas). After genetic analysis revealing c.152A>G (p.Tyr51Cys) mutation at the DNAJC30 gene, LHON was suggested. She was prescribed with idebenone and her visual acuity resolved to normal at 4-year follow-up.Conclusion: This case further expands the clinical presentations of DNAJC30-related LHON and underscores the importance of considering LHON in patients with demyelinating syndrome presenting with severe bilateral visual loss and presumed optic neuritis unresponsive to steroids.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"246-253"},"PeriodicalIF":0.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macular Morphological Changes in Familial Exudative Vitreoretinopathy with Macular Traction on OCT. 家族性渗出性玻璃体视网膜病变伴黄斑牵引的黄斑形态改变。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-03-03 eCollection Date: 2025-01-01 DOI: 10.1159/000545011

Asaki Hirai, Yota Kikuchi, Yuki Ohara, Toshihiko Ohta, Shintaro Nakao

{"title":"Macular Morphological Changes in Familial Exudative Vitreoretinopathy with Macular Traction on OCT.","authors":"Asaki Hirai, Yota Kikuchi, Yuki Ohara, Toshihiko Ohta, Shintaro Nakao","doi":"10.1159/000545011","DOIUrl":"10.1159/000545011","url":null,"abstract":"Introduction: We aimed to report macular morphological changes observed on optical coherence tomography (OCT) in a child with familial exudative vitreoretinopathy (FEVR), experiencing macular traction caused by fibrovascular tissue (FT), who underwent vitrectomy.Case presentation: A 7-year-old girl presented with the chief complaint of decreased visual acuity in the left eye during a school examination. Fundus examination revealed retinal folds with FT extending from the peripheral retina to the posterior pole of the left eye. Despite interventions such as retinal photocoagulation and encircling buckling aimed at reducing the traction on the macula, OCT revealed persistent deep retinal folds and a thickened outer nuclear layer (ONL), indicating gradually increasing macular traction, which contributed to vision loss. A subsequent vitrectomy alleviated the macular traction, enhanced the retinal morphology, and reduced ONL thickening regardless of persistent ectopic inner foveal layers.Conclusions: Macular morphological changes before and after vitrectomy in a pediatric case of FEVR can be observed using OCT. Vitrectomy with FT removal may be effective in partially improving macular morphology in FEVR with macular traction.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"239-245"},"PeriodicalIF":0.5,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11961152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electromagnetic Iontophoresis: A Novel Nonsurgical Method for the Treatment of Dense Vitreous and Retinal Hemorrhages. 电磁离子导入：一种新的非手术治疗玻璃体和视网膜密集出血的方法。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-27 eCollection Date: 2025-01-01 DOI: 10.1159/000544755

Umut Arslan, Deniz Arslan, Emin Özmert

{"title":"Electromagnetic Iontophoresis: A Novel Nonsurgical Method for the Treatment of Dense Vitreous and Retinal Hemorrhages.","authors":"Umut Arslan, Deniz Arslan, Emin Özmert","doi":"10.1159/000544755","DOIUrl":"10.1159/000544755","url":null,"abstract":"Introduction: Vitreous, retinal, and suprochoroidal hemorrhages might develop secondary to trauma, retinal tear or detachment, neovascularization due to ischemic retina. If the clearance of retinal and vitreous hemorrhages can be accelerated, more effective treatments can be planned for the underlying pathology.Case presentations: We present 6 different cases with dense vitreous, preretinal, and subretinal hemorrhages due to Valsalva retinopathy, polypoid choroidal vasculopathy, diabetic retinopathy, neovascular age-related macular degeneration, retinitis pigmentosa with vasculitis, and myopic choroidal neovascularization. To accelerate the clearance of these dense intraocular hemorrhages, a novel nonsurgical method of electromagnetic iontophoresis (MagnoVision™) was used together with some appropriate medications in an outpatient setting without any complications or side effects. In all cases, liquefaction of the intraocular hemorrhage began by 5 days and mostly resolved by 10 days. This nonsurgical rapid clearance allowed us to diagnose and evaluate the underlying retinal and choroidal pathologies earlier and to treat them appropriately as early as possible.Conclusion: Combined use of electromagnetic iontophoresis, subtenon platelet-rich plasma and bevacizumab injection, and oral bromelain can be considered as an effective and safe new treatment method for vitreous and retinal hemorrhages without any need for surgical intervention.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"221-231"},"PeriodicalIF":0.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi. 伴脉络膜痣的眼息肉样脉络膜血管病变6例。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-19 eCollection Date: 2025-01-01 DOI: 10.1159/000543643

Andrea Gaggino, Leandro Inferrera, Serena Milan, Marianna Presotto, Daniele Tognetto

{"title":"Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi.","authors":"Andrea Gaggino, Leandro Inferrera, Serena Milan, Marianna Presotto, Daniele Tognetto","doi":"10.1159/000543643","DOIUrl":"10.1159/000543643","url":null,"abstract":"Introduction: The aim of this study was to report the cases of 6 patients with the coexistence of polypoidal choroidal vasculopathy (PCV) and choroidal nevi.Case presentation: Six patients with the coexistence of PCV and choroidal nevi were thoroughly evaluated by slit-lamp biomicroscopy examination, color fundus photography, optical coherence tomography (OCT), OCT angiography (OCT-A), fluorescein angiography (FA), indocyanine green angiography (ICG-A), fundus blue autofluorescence (BAF), and ocular ultrasound (OU). The typical features of PCV and nevi were present in all patients, three of whom were treated with intravitreal anti-angiogenic agents. In each clinical case, the choroidal Haller's vessels adjacent to the nevus were visibly more dilated compared to normal. Color fundus photography, OCT, OCT-A, FA, ICG-A, BAF, and OU revealed similar findings across all cases. Observations revealed that choroidal nevi could instigate modifications in the outer retina, resulting in persistent alterations capable of triggering the formation of neovascularization.Conclusion: The occurrence of a PCV alongside nevus is an uncommon complication. Findings from all exams performed were consistent across all cases, highlighting the potential link between PCV and nevi.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"182-193"},"PeriodicalIF":0.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0