Case Reports in Ophthalmology最新文献

Hypertensive Disc Edema or Ocular Syphilis? A Case Report of the Great Masquerader. 高血压椎间盘水肿还是眼梅毒？大假面舞会的个案报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.1159/000545491

Nicole Oska, Michael Saad, Hassan Tokko

{"title":"Hypertensive Disc Edema or Ocular Syphilis? A Case Report of the Great Masquerader.","authors":"Nicole Oska, Michael Saad, Hassan Tokko","doi":"10.1159/000545491","DOIUrl":"10.1159/000545491","url":null,"abstract":"Introduction: Ocular syphilis is a rare manifestation of syphilis caused by Treponema pallidum which can occur at any stage of infection. It most commonly presents as posterior or panuveitis but can involve various ocular structures, complicating diagnosis.Case presentation: We describe a case of a 38-year-old female with a 7-month history of progressive blurry vision, floaters, flashes, and photophobia. Upon presentation to the emergency department, the patient's symptoms were initially attributed to a hypertensive emergency given fundoscopic examination revealing of optic disc edema. Despite resolution of hypertensive episode, the patient's symptoms persisted and she presented to our ophthalmology clinic where optical coherence tomography (OCT) showed ellipsoid zone disruption and hyperreflective deposits. Routine screening done at the emergency department for sexually transmitted infections indicated infection with syphilis and human immunodeficiency virus (HIV), for which the patient was instructed to return to the hospital for treatment. Cerebrospinal fluid (CSF) analysis confirmed diagnosis of neurosyphilis, and the patient was treated with 14 days of intravenous penicillin G.Conclusion: This case highlights the diagnostic challenges posed by ocular syphilis, especially when overshadowed by other conditions like hypertension. This patient's atypical presentation of optic neuritis without uveitis underscores the necessity of considering ocular syphilis in patients with chronic unexplained visual changes, particularly in high-risk populations.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"346-352"},"PeriodicalIF":0.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-Operative Endophthalmitis following Routine Photorefractive Keratectomy. 常规光屈光性角膜切除术后眼内炎。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-29 eCollection Date: 2025-01-01 DOI: 10.1159/000546142

Barry Power, Michael Wang, Alexandra Z Crawford, Shanu Subbiah

{"title":"Post-Operative Endophthalmitis following Routine Photorefractive Keratectomy.","authors":"Barry Power, Michael Wang, Alexandra Z Crawford, Shanu Subbiah","doi":"10.1159/000546142","DOIUrl":"10.1159/000546142","url":null,"abstract":"Introduction: Endophthalmitis is an exceptionally rare but devastating complication following laser corneal refractive surgery.Case presentation: We present a case of Pseudomonas aeruginosa endophthalmitis following routine myopic photorefractive keratectomy with mitomycin C application. The patient was referred to a tertiary ophthalmic service with severe post-operative infectious keratitis following initial management at another centre and was treated with intensive fortified antibiotics. The eye subsequently developed endophthalmitis with corneal perforation, necessitating urgent pars plan vitrectomy facilitated by a temporary keratoprosthesis and subsequent therapeutic penetrating keratoplasty. During anaesthetic induction, the patient developed anaphylaxis, most likely secondary to succinylcholine. Aggressive posterior positive pressure was encountered intra-operatively, resulting in spontaneous extrusion of the crystalline lens. We postulate that the posterior positive pressure was caused by several factors, including massive inflammation, and fluid shifts secondary to anaphylaxis and its associated management. The positive pressure was successfully managed and a keratoprosthesis was secured, allowing completion of vitrectomy and therapeutic penetrating keratoplasty. At 6-month follow-up, the vision remains at light perception.Conclusion: Endophthalmitis is an exceptionally rare but devastating complication following laser corneal refractive surgery, and the use of mitomycin C might have contributed to the rapid progression observed in the current case. Our report also highlights that acute anaphylaxis and its management can lead to posterior positive pressure, and measures should be taken to reduce the potential impacts before intraocular surgery and full-thickness incisions are made.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"353-359"},"PeriodicalIF":0.5,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Melanoma-Associated Retinopathy Presenting with Ocular Symptoms as the Initial Manifestation: A Case Report. 以眼部症状为首发表现的黑色素瘤相关视网膜病变1例

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-26 eCollection Date: 2025-01-01 DOI: 10.1159/000545942

Bo Zhou, Guoqin Li, Shengbo Wang, Fang Zhou, Peng Wu

{"title":"A Case of Melanoma-Associated Retinopathy Presenting with Ocular Symptoms as the Initial Manifestation: A Case Report.","authors":"Bo Zhou, Guoqin Li, Shengbo Wang, Fang Zhou, Peng Wu","doi":"10.1159/000545942","DOIUrl":"10.1159/000545942","url":null,"abstract":"Introduction: Melanoma-associated retinopathy (MAR) is a distinct subset within the spectrum of retinal-dysfunction disorders. It is triggered by the cross-reaction between circulating antibodies originating from malignant melanoma (MM) and retinal antigens. The timely identification of paraneoplastic retinal diseases is crucial, as it can significantly contribute to the early diagnosis and treatment of underlying malignancies. Currently, increasing awareness of the early clinical manifestations of MAR is essential for clinicians to detect primary or metastatic MMs at an earlier stage.Case presentation: This report details a case of a patient who initially presented with night blindness and visual field defects as the primary symptoms. Through a comprehensive and systematic examination process, which involved detailed ophthalmological examinations and multidisciplinary diagnostic approaches, esophageal, and cardia MM was ultimately diagnosed. The patient was referred to an external hospital for comprehensive antitumor management, and posttreatment, the patient self-reported a notable improvement compared to the pretreatment state.Conclusion: The purpose of sharing this case is to clarify the early clinical manifestations of MAR. It is anticipated that this will prompt clinicians to enhance their vigilance and identify primary or metastatic MMs earlier. Early treatment of the primary disease not only has the potential to reduce the risk of irreversible immune-mediated damage to retinal cells but also to improve visual outcomes. This highlights the significance of early diagnosis and intervention in the management of such diseases, providing important reference for clinicians.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"377-384"},"PeriodicalIF":0.5,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metastatic Cutaneous Melanoma Presenting with Choroidal Metastasis Mimicking Lymphoma: A Case Report. 以脉络膜转移模拟淋巴瘤为表现的转移性皮肤黑色素瘤1例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-24 eCollection Date: 2025-01-01 DOI: 10.1159/000544926

Laura E Drew-Bear, Allison Drummond, Crystal Truong, Komal Desai

{"title":"Metastatic Cutaneous Melanoma Presenting with Choroidal Metastasis Mimicking Lymphoma: A Case Report.","authors":"Laura E Drew-Bear, Allison Drummond, Crystal Truong, Komal Desai","doi":"10.1159/000544926","DOIUrl":"10.1159/000544926","url":null,"abstract":"Introduction: Approximately 5% of patients with cutaneous melanoma develop distant metastases, and very rarely, can involve the eye and orbit. This case report discusses a patient with an unusual presentation of choroidal metastasis secondary to cutaneous melanoma.Case presentation: A 76-year-old man with a past medical history of cutaneous melanoma on the right shoulder status post radiation presented to the ocular oncology clinic with a 3-month history of decreased vision, occasional pain, and floaters in the right eye. Initial examination revealed a visual acuity of hand motion in the right eye, intraocular pressure of 5 mm Hg, and no view to the fundus due to vitreous hemorrhage. B-scan did not show a retinal tear, retinal detachment, or intraocular tumor. The patient underwent pars plana vitrectomy of the right eye where massive choroidal thickening with subretinal yellow deposits obstructing the optic nerve head was seen, initially concerning lymphoma. On postoperative week one, visual acuity remained hand motion and the fundus exam showed clear vitreous and retinal/choroidal infiltrates obscuring the optic nerve and macula. Repeat B-scan showed retinal and choroidal thickening with exudates. Cytology results from surgery later revealed malignant cells consistent with melanoma. The patient underwent ocular radiation but eventually progressed to no light perception visual acuity. He is currently under observation with the goal of palliative care.Conclusion: This case highlights the importance of maintaining a high level of suspicion for metastasis in the setting of melanoma history even when presentation can be atypical. Early recognition of choroidal metastasis allows for timely intervention, improving the chances of preserving vision.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"360-365"},"PeriodicalIF":0.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed Onset of Central Serous Chorioretinopathy following Corticosteroid Treatment for Giant Cell Arteritis: A Case Report. 巨细胞动脉炎经皮质类固醇治疗后迟发性中心性浆液性脉络膜视网膜病变1例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.1159/000546053

Bava Jeyanathan, Jonathan Micieli

{"title":"Delayed Onset of Central Serous Chorioretinopathy following Corticosteroid Treatment for Giant Cell Arteritis: A Case Report.","authors":"Bava Jeyanathan, Jonathan Micieli","doi":"10.1159/000546053","DOIUrl":"10.1159/000546053","url":null,"abstract":"Introduction: Central serous chorioretinopathy (CSCR) is a known complication of corticosteroid use, characterized by the accumulation of subretinal fluid (SRF), which can lead to changes in vision. Giant cell arteritis (GCA) is a systemic vasculitis that often necessitates high-dose corticosteroid treatment to prevent serious complications including permanent vision loss. Although the association between CSCR and corticosteroids is well established, its occurrence in patients diagnosed with GCA remains rarely reported in literature.Case presentation: We present a case of a 71-year-old man who developed CSCR following 6 months of corticosteroid treatment for GCA. The patient presented with decreased vision in the left eye for 10 days, prompting ophthalmologic evaluation. Initial visual acuity (VA) was measured at 20/60, and OCT identified the presence of SRF, confirming CSCR as the underlying etiology. Following gradual tapering of his prednisone dosage, subsequent OCT confirmed significant reduction in SRF, with VA improving to 20/30 within 3 months.Conclusion: This case highlights the importance of considering CSCR in the differential diagnosis of new or worsening visual symptoms in GCA patients receiving corticosteroids. The risk for corticosteroid-induced CSCR in these patients creates a diagnostic challenge, as worsening vision may be incorrectly attributed to disease progression rather than being recognized as a treatment-related adverse effect. This case emphasizes the importance of early recognition of CSCR and highlights the need for interdisciplinary collaboration between rheumatologists and ophthalmologists to ensure appropriate management for patients with GCA.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"372-376"},"PeriodicalIF":0.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aqueous Humor Liquid Biopsy to Exclude Retinoblastoma for a Child with an Intraocular Mass. 儿童眼内肿块房水活检排除视网膜母细胞瘤。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-21 eCollection Date: 2025-01-01 DOI: 10.1159/000545924

Andrew J Nelson, Susanna Park, Marvin D Nelson, Jesse L Berry

{"title":"Aqueous Humor Liquid Biopsy to Exclude Retinoblastoma for a Child with an Intraocular Mass.","authors":"Andrew J Nelson, Susanna Park, Marvin D Nelson, Jesse L Berry","doi":"10.1159/000545924","DOIUrl":"10.1159/000545924","url":null,"abstract":"Introduction: Intraocular masses in children may present diagnostic dilemmas when clinical examination and imaging are insufficient to diagnose or exclude retinoblastoma. Furthermore, direct biopsy is contraindicated because of the risk of tumor seeding in retinoblastoma. Recent research has shown that aqueous humor biopsy is a safe method of obtaining cell-free DNA which can be used to diagnose retinoblastoma with high sensitivity and specificity, which provides a significant benefit in cases when the diagnosis is otherwise unclear.Case presentation: An 11-month-old female presented with poor visual behavior since birth and an intraocular mass in the left eye. Examination under anesthesia revealed a detached retina rolled into a stalk attached to the optic nerve in the right eye and a white retrolental mass with perfused vessels in the left eye. Magnetic resonance imaging demonstrated a heterogeneous mass filling the left globe with diffusion restriction and contract enhancement. Aqueous humor liquid biopsy was performed in both eyes with low DNA yield and no mutations associated with retinoblastoma were identified. The patient was observed with no interval change in examination for 6 months.Conclusion: Aqueous humor liquid biopsy can be used to exclude a diagnosis of retinoblastoma in cases of pediatric intraocular mass with uncertain diagnosis.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"366-371"},"PeriodicalIF":0.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late-Onset Subretinal Silicone Oil Migration through Optic Disc Coloboma. 迟发性视网膜下硅油通过视盘结肠瘤迁移。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-04 eCollection Date: 2025-01-01 DOI: 10.1159/000545661

Or Shmueli, Tareq Jaouni

{"title":"Late-Onset Subretinal Silicone Oil Migration through Optic Disc Coloboma.","authors":"Or Shmueli, Tareq Jaouni","doi":"10.1159/000545661","DOIUrl":"https://doi.org/10.1159/000545661","url":null,"abstract":"Introduction: This report describes a case of late onset subretinal silicone oil migration in an eye with congenital optic disc coloboma and its treatment.Case presentation: A 15-year-old male with a history of left eye congenital optic disc coloboma and amblyopia presented with a third recurrence of retinal detachment (RD) with proliferative vitreoretinopathy. The patient underwent PPV, subretinal fluid drainage through a peripheral retinotomy, silicone oil tamponade, and endolaser around the coloboma and retinotomy. The retina re-attached successfully. However, 14 months postoperatively examination revealed high intraocular pressure (IOP) of 33 mm Hg and a sub-macular bubble of silicone oil was evident. The patient underwent sub-macular silicone oil removal.Conclusion: Here we describe the unique late-onset subretinal migration of intravitreal silicone oil following RD repair in an eye with optic disc coloboma in association with raised IOP. This case demonstrates potential mechanisms of subretinal silicone oil migration through the coloboma that serves as a passage and an increased IOP, which drives the oil from the vitreous to the subretinal space.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"331-335"},"PeriodicalIF":0.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Retinal Vasculitis to Stroke, from Systemic Findings to Diagnosis, the Necessity of Multidisciplinary Management in Behçet's Disease: A Case Report. 从视网膜血管炎到中风，从系统发现到诊断，behet病多学科管理的必要性：一个病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-04 eCollection Date: 2025-01-01 DOI: 10.1159/000545635

Sayena Jabbehdari, Anthony Oganov, Sami H Uwaydat

{"title":"From Retinal Vasculitis to Stroke, from Systemic Findings to Diagnosis, the Necessity of Multidisciplinary Management in Behçet's Disease: A Case Report.","authors":"Sayena Jabbehdari, Anthony Oganov, Sami H Uwaydat","doi":"10.1159/000545635","DOIUrl":"https://doi.org/10.1159/000545635","url":null,"abstract":"Introduction: Behçet's disease (BD) is a rare, chronic multisystem disorder characterized by occlusive vasculitis, which can present with a variety of systemic and ocular manifestations. The diagnosis of BD is often challenging, particularly in populations with low prevalence. Retinal vasculitis and stroke can be key indicators, and the early involvement of a multidisciplinary team is essential for accurate diagnosis and management to prevent long-term complications.Case presentation: A 40-year-old African American female presented with vision changes in her left eye and a history of multiple strokes. Examination revealed retinal ischemia and vasculitis, raising suspicion of an underlying systemic condition. Extensive workup for infectious and inflammatory causes was negative. As her condition progressed, the patient developed genital ulcers, prompting further investigation. A biopsy of the genital ulcer confirmed BD, and a multidisciplinary approach involving ophthalmology, rheumatology, and neurology was initiated. The patient was treated with high-dose corticosteroids, immunosuppressive therapy, and intravitreal corticosteroids, leading to stabilization of her ocular and systemic symptoms. Despite her history of stroke, the collaboration between specialties facilitated better management of her condition and prevention of further complications.Conclusion: It is crucial to include BD as a potential diagnosis in cases of ophthalmic or systemic vasculitis, even in regions and populations with low prevalence. Early referral to a rheumatologist for cases of vasculitis and timely collaboration are essential for accurate diagnosis, prevention of systemic complications, and appropriate management.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"317-322"},"PeriodicalIF":0.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transsphenoidal Optic Canal Decompression to Manage a Venous Malformation of the Optic Canal: A Case Report. 经蝶窦视神经管减压术治疗视神经管静脉畸形1例。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.1159/000545542

Khizar Rana, David Curragh, Valerie Juniat, Sandy Patel, James Slattery, Dinesh Selva

{"title":"Transsphenoidal Optic Canal Decompression to Manage a Venous Malformation of the Optic Canal: A Case Report.","authors":"Khizar Rana, David Curragh, Valerie Juniat, Sandy Patel, James Slattery, Dinesh Selva","doi":"10.1159/000545542","DOIUrl":"https://doi.org/10.1159/000545542","url":null,"abstract":"Introduction: Intracanalicular vascular malformations are rare. This report describes a case of compressive optic neuropathy secondary to an intracanalicular venous malformation managed with endoscopic transsphenoidal optic canal decompression.Case presentation: A 43-year-old female presented with an 18-month history of painless vision loss secondary to an intracanalicular venous malformation causing compressive optic neuropathy. Ophthalmic examination showed reduced visual acuity and color vision, relative afferent pupillary defect, and optic disc pallor. Imaging findings were consistent with a slow-flow vascular malformation. An endoscopic transsphenoidal optic canal decompression was performed. The lesion was found to be wrapping around the optic nerve. At follow-up after 1 year, visual acuity had improved along with restoration of full color vision and visual fields.Conclusion: This case highlights the successful use of endoscopic transsphenoidal optic canal decompression to treat compressive optic neuropathy caused by an intracanalicular venous malformation.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"313-316"},"PeriodicalIF":0.5,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cholesterolosis Bulbi in an Eye with Retinal Capillary Hemangioma: A Rare Association with Chemical Analysis. 伴有视网膜毛细血管瘤的眼球胆固醇升高：与化学分析的罕见关联。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.1159/000545564

Abdelwahab Aleshawi, Rami Al-Dwairi, Mohammad Al Qudah, Abdallah Sharayah, Mahmood Al Nuaimi, Hashem Abu Serhan

{"title":"Cholesterolosis Bulbi in an Eye with Retinal Capillary Hemangioma: A Rare Association with Chemical Analysis.","authors":"Abdelwahab Aleshawi, Rami Al-Dwairi, Mohammad Al Qudah, Abdallah Sharayah, Mahmood Al Nuaimi, Hashem Abu Serhan","doi":"10.1159/000545564","DOIUrl":"https://doi.org/10.1159/000545564","url":null,"abstract":"Introduction: Cholesterolosis bulbi is an ocular condition characterized by the accumulation of cholesterol crystals in the vitreous cavity. This case describes the development of anterior chamber cholesterolosis bulbi secondary to retinal capillary hemangioma.Case presentation: A 26-year-old female, tested negative for von Hippel-Lindau (VHL) syndrome, presented with yellow shinny crystals filling the anterior chamber of the left eye and similar depositions filling the vitreous cavity along with reactivated hemangioma with new feeder vessels. She was diagnosed previously with bilateral capillary retinal hemangiomas. Anterior chamber and vitreous washout and endo-laser photocoagulation for the hemangioma were performed. Analysis of the aqueous sample revealed numerous well-demarcated, rectangular, or polygonal lipid-like crystals on light microscopy. Cholesterolosis bulbi secondary to retinal capillary hemangioma was established.Conclusions: Cholesterolosis bulbi secondary to retinal capillary hemangioma is a rare association and would warrant for extensive tumor or associated complications.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"336-340"},"PeriodicalIF":0.5,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0