Intracameral Povidone-Iodine for Multidrug-Resistant Pseudomonas aeruginosa Exogenous Endophthalmitis: A Case Report and Literature Review.

IF 0.6 Q4 OPHTHALMOLOGY

Case Reports in Ophthalmology Pub Date : 2025-06-05 eCollection Date: 2025-01-01 DOI:10.1159/000546659

Fatma Kassem Mohamed, Mohamed S I Mohamed, Maha M El Shafei, Anant Pai, Hashem Abu Serhan

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引用次数: 0

Abstract

Introduction: The objective of this study was to report successful management of multidrug-resistant Pseudomonas aeruginosa endophthalmitis in a patient with a complex ophthalmic history using intracameral povidone-iodine (PI).

Case presentation: A 59-year-old male with a history of cataract surgery and multiple retinal detachment repairs presented with acute left eye pain, chemosis, redness, and vision loss. Diagnosis of exogenous endophthalmitis was made. The patient had anterior chamber washout, along with aqueous and vitreous tapping with intravitreal vancomycin, ceftazidime, and intravenous ciprofloxacin. Since infection persisted despite antibiotic therapies, a repeated anterior chamber washout followed by intracameral injection of PI 0.1% was done. Vision improved to 6/60 with no bacterial regrowth or inflammatory membranes on discharge and follow-up.

Conclusions: Intracameral PI may offer a solution for endophthalmitis cases where standard antibiotics are ineffective. This case supports the potential role of PI in managing resistant intraocular infections.

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眼内注射聚维酮碘治疗多药耐药铜绿假单胞菌外源性眼内炎1例并文献复习。

简介：本研究的目的是报道使用眼内聚维酮碘（PI）成功治疗具有复杂眼科病史的多药耐药铜绿假单胞菌眼内炎。病例介绍：59岁男性，有白内障手术和多次视网膜脱离修复史，表现为急性左眼疼痛、化脓、红肿和视力丧失。诊断为外源性眼内炎。患者前房冲洗，玻璃体内注射万古霉素、头孢他啶和环丙沙星进行水样和玻璃体轻叩。由于抗生素治疗后感染仍然存在，因此进行了反复的前房冲洗，随后进行了肠腔内注射PI 0.1%。出院和随访时视力改善至6/60，无细菌再生或炎症膜。结论：内窥镜内窥镜可为标准抗生素无效的眼内炎患者提供一种解决方案。本病例支持PI在治疗难治性眼内感染中的潜在作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Ophthalmology OPHTHALMOLOGY-

CiteScore

0.90

自引率

0.00%

发文量

129

审稿时长

12 weeks

期刊介绍： This peer-reviewed online-only journal publishes original case reports covering the entire spectrum of ophthalmology, including prevention, diagnosis, treatment, toxicities of therapy, supportive care, quality-of-life, and survivorship issues. The submission of negative results is strongly encouraged. The journal will also accept case reports dealing with the use of novel technologies, both in the arena of diagnosis and treatment. Supplementary material is welcomed. The intent of the journal is to provide clinicians and researchers with a tool to disseminate their personal experiences to a wider public as well as to review interesting cases encountered by colleagues all over the world. Universally used terms can be searched across the entire growing collection of case reports, further facilitating the retrieval of specific information. Following the open access principle, the entire contents can be retrieved at no charge, guaranteeing easy access to this valuable source of anecdotal information at all times.