Case Reports in Ophthalmology最新文献_第2页

Reactivation of Varicella-Zoster Virus Keratitis after Recombinant Herpes Zoster Vaccination: A Case Report and Literature Review. 重组带状疱疹疫苗接种后水痘-带状疱疹病毒角膜炎再活化一例报告及文献复习。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-23 eCollection Date: 2026-01-01 DOI: 10.1159/000552965

Santiago Mejía-Martínez, Sara M Mejía-Castro

{"title":"Reactivation of Varicella-Zoster Virus Keratitis after Recombinant Herpes Zoster Vaccination: A Case Report and Literature Review.","authors":"Santiago Mejía-Martínez, Sara M Mejía-Castro","doi":"10.1159/000552965","DOIUrl":"10.1159/000552965","url":null,"abstract":"Introduction: Varicella-zoster virus (VZV) keratitis following recombinant herpes zoster (HZ) vaccination is rare, and its underlying mechanisms remain poorly understood. Sporadic cases of ocular inflammatory reactivation have been reported after vaccination, particularly in patients with a history of HZ infection.Case presentation: A 68-year-old woman with a history of trigeminal HZ without prior corneal involvement developed VZV keratitis 2 months after receiving the recombinant HZ vaccine (Shingrix®). The condition progressed to neurotrophic keratitis, requiring advanced ocular surface therapy, including autologous serum and topical insulin, with favorable visual and symptomatic outcomes.Conclusion: Reactivation of VZV keratitis after HZ vaccination is an uncommon but clinically relevant event. Ocular reactivation may occur even in patients without previous corneal involvement and may lead to chronic complications, supporting the need for close ophthalmologic follow-up in patients with a history of HZ infection.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"908-915"},"PeriodicalIF":0.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Syphilitic Neuroretinitis with Positive Cytomegalovirus Serology in an Immunocompetent Adolescent: A Case Report. 免疫功能正常青少年巨细胞病毒血清学阳性的梅毒性神经视网膜炎一例报告。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-21 eCollection Date: 2026-01-01 DOI: 10.1159/000553652

Sundip Dware Chhetri, Meena Kunwar, Ram Krishna Baral, Alina Karki, Sabina Maharjan, Basanta Kumar Bastola, Mohini Thapa, Bibek Pun, Sudeep Lal Rajbhandari

{"title":"Syphilitic Neuroretinitis with Positive Cytomegalovirus Serology in an Immunocompetent Adolescent: A Case Report.","authors":"Sundip Dware Chhetri, Meena Kunwar, Ram Krishna Baral, Alina Karki, Sabina Maharjan, Basanta Kumar Bastola, Mohini Thapa, Bibek Pun, Sudeep Lal Rajbhandari","doi":"10.1159/000553652","DOIUrl":"10.1159/000553652","url":null,"abstract":"Introduction: Neuroretinitis is an inflammatory optic neuropathy characterized by optic disc edema followed by macular star formation. It is most commonly caused by Bartonella henselae, but other infectious etiologies including syphilis and cytomegalovirus (CMV) should be considered, particularly due to their potential for severe visual morbidity if untreated.Case presentation: A 17-year-old immunocompetent female presented with unilateral visual blurring and headache. Ophthalmologic examination revealed optic disc edema, macular star exudates, and peripapillary hemorrhages in the right eye. Dermatologic examination revealed features consistent with secondary syphilis, and the diagnosis was further supported by laboratory investigations confirming syphilis. Serologic testing also demonstrated positive CMV IgM and IgG antibodies. HIV testing was negative. The patient was treated with intravenous ceftriaxone and ganciclovir followed by oral valganciclovir. Complete anatomical and functional recovery was achieved with restoration of visual acuity.Conclusion: This case highlights the importance of comprehensive infectious evaluation in neuroretinitis, even in immunocompetent individuals. Early diagnosis and appropriate targeted antimicrobial therapy are essential to prevent permanent visual loss.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"924-933"},"PeriodicalIF":0.6,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toxic Anterior Segment Syndrome following XEN Gel Stent Implantation: A Rare Complication in Minimally Invasive Glaucoma Surgery - Case Report. XEN凝胶支架植入术后毒性前段综合征：微创青光眼手术中一种罕见的并发症- 1例报告。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-21 eCollection Date: 2026-01-01 DOI: 10.1159/000553653

Pau Marjalizo, Julia Seco Orriols, Josep Torras Sanvicens, Maria Jesús Muniesa Royo

{"title":"Toxic Anterior Segment Syndrome following XEN Gel Stent Implantation: A Rare Complication in Minimally Invasive Glaucoma Surgery - Case Report.","authors":"Pau Marjalizo, Julia Seco Orriols, Josep Torras Sanvicens, Maria Jesús Muniesa Royo","doi":"10.1159/000553653","DOIUrl":"10.1159/000553653","url":null,"abstract":"Introduction: Toxic anterior segment syndrome (TASS) is a rare, sterile, acute inflammatory reaction of the anterior segment following intraocular surgery. Although it is most commonly associated with cataract surgery, it has been reported after a variety of ophthalmic procedures. To our knowledge, no case of TASS following XEN Gel Stent Implantation has been previously described in the literature.Case presentation: An 85-year-old pseudophakic woman with primary open-angle glaucoma developed TASS after uneventful XEN63 implantation. Within 24 h postoperatively, the patient presented with diffuse limbus-to-limbus corneal edema, anterior chamber inflammation, and absence of pain or posterior segment involvement. Despite prompt and intensive topical corticosteroid therapy, she developed irreversible corneal decompensation, iris atrophy, and fixed nonreactive mydriasis. No additional cases were identified in the same surgical setting, suggesting a patient- or procedure-specific trigger. Potential causative factors included intracameral agents (lidocaine, acetylcholine, cefuroxime, viscoelastic material), possible migration of mitomycin C through the XEN stent lumen, or an inflammatory response to the gelatin-based device itself.Conclusions: This case demonstrates that TASS can occur following minimally invasive glaucoma surgery, including XEN Gel Stent implantation, and may result in severe and irreversible ocular sequelae. It underscores the importance of heightened postoperative vigilance and strict preventive protocols even in procedures perceived as low risk.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"879-885"},"PeriodicalIF":0.6,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13499647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Iris Capture after Iris Suturing following Scleral-Sutured Intraocular Lens Fixation: A Case Report. 巩膜缝合人工晶状体固定术后虹膜缝合后复发虹膜捕获1例报告。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-21 eCollection Date: 2026-01-01 DOI: 10.1159/000553616

Kayano Shioda, Tomoyuki Kunishige, Fumiki Okamoto

{"title":"Recurrent Iris Capture after Iris Suturing following Scleral-Sutured Intraocular Lens Fixation: A Case Report.","authors":"Kayano Shioda, Tomoyuki Kunishige, Fumiki Okamoto","doi":"10.1159/000553616","DOIUrl":"https://doi.org/10.1159/000553616","url":null,"abstract":"Introduction: Capture of the intraocular lens (IOL) optic by the iris or pupillary margin is defined as iris capture, and this postoperative complication occurs after scleral-sutured IOL fixation and sutureless intrascleral fixation. However, the optimal placement of iris sutures for preventing recurrence has yet to be adequately described.Case presentation: We report on the case of a 72-year-old man with ocular hypertension 1 year after scleral-sutured IOL fixation in the left eye who was referred for iris capture. Although topical medication was initially used to relieve the iris capture, it later became refractory. Iris suturing was initially performed at the 12 and 6 o'clock positions. However, at 1 month postoperatively, recurrent iris capture was subsequently observed. As a result, a second iris suturing procedure centered at the 8 o'clock position was performed at the documented capture site. In this second iris suturing procedure, which is shown in the online supplementary intraoperative video, an additional suture was placed at the documented 8 o'clock capture site. The clinical course has remained favorable and there has been no recurrence observed.Conclusion: Current results suggest that iris suturing is an effective treatment option for recurrent iris capture after scleral-sutured IOL fixation. Moreover, further recurrence may be prevented by utilizing suture placement guided by the documented site of recurrence.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"865-871"},"PeriodicalIF":0.6,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13489607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Partial Spontaneous Regression of the Late-Onset Choroidal Neovascularization after Full-Thickness Macular Hole Surgery without Anti-VEGF Therapy: A Case Report. 未经抗vegf治疗的全层黄斑孔手术后迟发性脉络膜新生血管部分自发消退一例报告。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-16 eCollection Date: 2026-01-01 DOI: 10.1159/000553614

Gulnar Zhurgumbayeva, Sanzhar Sambet, Dastan Kyrykbayev, Elnur Asan, Farrukh Umarov, Mukhit Kulmaganbetov

{"title":"Partial Spontaneous Regression of the Late-Onset Choroidal Neovascularization after Full-Thickness Macular Hole Surgery without Anti-VEGF Therapy: A Case Report.","authors":"Gulnar Zhurgumbayeva, Sanzhar Sambet, Dastan Kyrykbayev, Elnur Asan, Farrukh Umarov, Mukhit Kulmaganbetov","doi":"10.1159/000553614","DOIUrl":"https://doi.org/10.1159/000553614","url":null,"abstract":"Introduction: The development of choroidal neovascularization (CNV) following macular surgery, including repair of full-thickness macular holes (FTMHs), is a clinically significant but rare complication, particularly in patients with pre-existing retinal pigment epithelium-Bruch's membrane complex changes.Case presentation: We report a 71-year-old female patient who developed CNV in the right eye following surgical treatment for an FTMH. Regular monthly follow-up examinations allowed us to track the dynamics of the disease. Optical coherence tomography (OCT) and fluorescein angiography initially suggested stability. However, approximately 7 months post-surgery, a structural debut of exudative changes was observed. Anti-VEGF therapy was not administered to this eye, allowing for the observation of the natural course, which included progression followed by partial spontaneous regression.Conclusion: Our case highlights the importance of regular OCT monitoring after macular hole surgery in patients with AMD risk factors. While structural stability was maintained for months, the sudden debut of exudation and its subsequent wavelike fluctuation without treatment underscores the complex natural history of post-surgical CNV.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"845-852"},"PeriodicalIF":0.6,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13489608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Occult Intraocular Eyelash Masquerading as Chronic Recurrent Uveitis: A Case Report. 隐匿眼内睫毛伪装成慢性复发性葡萄膜炎1例。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-16 eCollection Date: 2026-01-01 DOI: 10.1159/000553388

Hao Wu, Xiaoqing Chen, Dan Liang

{"title":"An Occult Intraocular Eyelash Masquerading as Chronic Recurrent Uveitis: A Case Report.","authors":"Hao Wu, Xiaoqing Chen, Dan Liang","doi":"10.1159/000553388","DOIUrl":"https://doi.org/10.1159/000553388","url":null,"abstract":"Introduction: Intraocular foreign bodies (IOFBs) can induce recurrent uveitis and may be easily overlooked when a plausible systemic etiology, such as HLA-B27 positivity, is present. This report documents a diagnostic challenge where an occult eyelash masqueraded as HLA-B27-associated disease.Case presentation: A 13-year-old female with HLA-B27 positivity presented with four episodes of recurrent unilateral anterior uveitis, initially diagnosed and treated as HLA-B27-associated uveitis. Following the resolution of active inflammation with medical therapy, a subtle iris protuberance was identified at the 5 o'clock position. Ultrasound biomicroscopy (UBM) confirmed a hyper-reflective foreign body embedded in the angle recess. Following successful surgical removal of an eyelash, the inflammation resolved rapidly with no recurrence over a 2-year follow-up period.Conclusion: This case underscores that occult IOFBs should be considered in the differential diagnosis of recalcitrant unilateral uveitis, even when systemic associations are present. Careful re-examination after inflammation subsides and the appropriate use of imaging modalities like UBM are essential to prevent diagnostic delays and preserve vision.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"860-864"},"PeriodicalIF":0.6,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13489612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Presumed Secondary Vitreoretinal Lymphoma with Response to Systemic Therapy Alone: Case Report. 假定继发性玻璃体视网膜淋巴瘤仅对全身治疗有反应：病例报告。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-16 eCollection Date: 2026-01-01 DOI: 10.1159/000553402

Alyssa C Huelsbeck, Colin P Froines, Julie E Chang, Gordon S Crabtree

{"title":"Presumed Secondary Vitreoretinal Lymphoma with Response to Systemic Therapy Alone: Case Report.","authors":"Alyssa C Huelsbeck, Colin P Froines, Julie E Chang, Gordon S Crabtree","doi":"10.1159/000553402","DOIUrl":"https://doi.org/10.1159/000553402","url":null,"abstract":"Introduction: Intraocular lymphoma is a rare malignancy with no standard treatment regimen. We describe a case of secondary vitreoretinal lymphoma (VRL) with excellent response to systemic chemotherapy alone without intravitreal treatment.Case presentation: A 72-year-old male with a diagnosis of stage IVA diffuse large B-cell lymphoma presented for evaluation of subretinal involvement with visual acuity of 20/20-3 in the right eye and 20/100 in the left eye. Fundus examination was largely unremarkable. Fundus autofluorescence (FAF) showed hyperautofluorescence in the macula with an area of hypoautofluorescence that could not be detected on examination. Ocular coherence tomography showed subretinal material in the macula. A biopsy was deferred, and the treatment plan involved observation of response to systemic chemotherapy. Six-month follow-up showed resolution of the subretinal material and near resolution of the hyperautofluorescence, consistent with response to treatment.Conclusion: Select cases of isolated secondary VRL may be appropriate for management with systemic chemotherapy alone. Multimodal imaging including FAF can demonstrate lesions that may be less apparent clinically. Imaging may also be used for characterization of lesions when biopsy is deferred.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"830-836"},"PeriodicalIF":0.6,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Variants in Mitochondrial Ribosomal RNA Genes MT-RNR1 and MT-RNR2 Identified in Hereditary Optic Neuropathy Initially Presenting as Normal Tension Glaucoma: A Case Report. 线粒体核糖体RNA基因MT-RNR1和MT-RNR2的新变异在遗传性视神经病变中被发现，最初表现为正常张力性青光眼：一例报告。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-15 eCollection Date: 2026-01-01 DOI: 10.1159/000553606

Amanda Tran, Jonathan Micieli

{"title":"Novel Variants in Mitochondrial Ribosomal RNA Genes MT-RNR1 and MT-RNR2 Identified in Hereditary Optic Neuropathy Initially Presenting as Normal Tension Glaucoma: A Case Report.","authors":"Amanda Tran, Jonathan Micieli","doi":"10.1159/000553606","DOIUrl":"https://doi.org/10.1159/000553606","url":null,"abstract":"Introduction: Hereditary optic neuropathy may be caused by various mitochondrial or nuclear DNA mutations affecting the mitochondrial function. A growing body of evidence shows that mutations in non-classical mitochondrial genes, including the ribosomal RNA genes MT-RNR1 and MT-RNR2, have been reported in patients with hereditary optic neuropathy, although their pathogenicity remains uncertain. Herein, we report a case initially diagnosed as normal tension glaucoma in which whole mtDNA sequencing identified 2 novel variants in MT-RNR1 and MT-RNR2.Case presentation: A 36-year-old man was referred for glaucoma assessment but was found to have bilateral symmetric temporal optic disc pallor and retinal nerve fibre layer thinning that was inconsistent with a glaucomatous pattern. Intraocular pressure (IOP), Humphrey visual fields, colour vision, and pupillary responses were normal. Genetic testing was negative for the 3 primary Leber's hereditary optic neuropathy (LHON) mutations but identified MT-RNR1:m.990T>C and MT-RNR2:m.2619A>G, both at 99.5% heteroplasmy and classified as ACMG class 3. Visual function remained stable at 6-month follow-up.Conclusion: Neither MT-RNR1 and MT-RNR2 variants could be definitively linked to the hereditary optic neuropathy in this patient, and they are best regarded as findings of uncertain significance. This case highlights a diagnostic pitfall as non-glaucomatous optic disc pallor can be mistaken for normal tension glaucoma and underscores the diagnostic value of whole mtDNA sequencing when primary LHON screening is negative.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"853-859"},"PeriodicalIF":0.6,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13489611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Annulated Surprise during Cataract Surgery: A Case Report. 白内障手术中的环状意外：1例报告。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-13 eCollection Date: 2026-01-01 DOI: 10.1159/000552389

Jorgos S Koulalis, Richard Hardi, Dennis Tappe, Sorcha Ni Dhubhghaill, Artemise Dugauquier

{"title":"Annulated Surprise during Cataract Surgery: A Case Report.","authors":"Jorgos S Koulalis, Richard Hardi, Dennis Tappe, Sorcha Ni Dhubhghaill, Artemise Dugauquier","doi":"10.1159/000552389","DOIUrl":"10.1159/000552389","url":null,"abstract":"Introduction: We report a pediatric case in which a retrolenticular Armillifer armillatus infestation mimicked a white cataract.Case presentation: A ten-year-old girl presented with a white cataract of her right eye during a humanitarian mission in the Democratic Republic of Congo. Fundoscopy was inaccessible. During surgery, an annulated worm-like parasite was found in the retrolenticular space. Further anamnesis was remarkable for regular snake and crocodile meat consumption, and a clinical diagnosis of ocular pentastomiasis was made. The parasite was morphologically and molecularly identified as A. armillatus. After surgery, fundoscopy showed diffuse retinal atrophy and the vision did unfortunately not improve. Human pentastomiasis is a rare, yet emerging zoonosis in rural tropical areas. Consumption of undercooked, infected snake (or rarely other reptile) meat may lead to visceral pentastomiasis, with uncommon ophthalmological involvement. Ocular pentastomiasis can be a devastating cause of vision loss in endemic regions.Conclusion: This case illustrates that a retrolenticular location of the parasite was likely responsible for a white cataract in an otherwise quiet, white eye, highlighting intraocular pentastomiasis as a potentially underdiagnosed cause of vision loss in endemic regions.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"681-686"},"PeriodicalIF":0.6,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13363135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148435228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Acanthamoeba Keratitis Secondary to Contaminated Contact Lens Suction Applicators: A Rare Case of Accessory-Mediated Transmission. 受污染的隐形眼镜吸吸器继发于双侧棘阿米巴角膜炎：一例罕见的附件传播病例。

IF 0.6

Case Reports in Ophthalmology Pub Date : 2026-07-09 eCollection Date: 2026-01-01 DOI: 10.1159/000553223

Eleanor Kerr, Kelvin K W Cheng, Mohammad Z Mustafa, Naing L Tint

{"title":"Bilateral Acanthamoeba Keratitis Secondary to Contaminated Contact Lens Suction Applicators: A Rare Case of Accessory-Mediated Transmission.","authors":"Eleanor Kerr, Kelvin K W Cheng, Mohammad Z Mustafa, Naing L Tint","doi":"10.1159/000553223","DOIUrl":"10.1159/000553223","url":null,"abstract":"Introduction: Acanthamoeba keratitis (AK) is a sight-threatening corneal infection primarily associated with contact lens wear. While lens and case hygiene are frequently emphasised, auxiliary tools such as suction applicators remain a neglected vector for transmission. This report highlights a case of bilateral AK where a contaminated suction applicator served as a likely vehicle for infection.Case presentation: A 57-year-old female long-term rigid gas permeable (RGP) lens wearer presented with a 2-week history of severe, bilateral ocular pain, redness, and photophobia. Slit-lamp examination revealed bilateral dendritic epithelial disruption and mild anterior chamber activity. The patient reported good contact lens hygiene but used a rubber suction applicator for daily lens use, which was routinely rinsed with tap water. Diagnosis was confirmed via corneal scrapings and polymerase chain reaction (PCR) for Acanthamoeba DNA. PCR analysis of washes from the suction device's lumen also returned positive for Acanthamoeba. Following a course of topical propamidine isethionate (Brolene) and topical chlorhexidine 0.02%, the keratitis fully resolved over several months. Final visual acuity was 6/12 (pinhole) in the right eye and 6/5 in the left.Conclusion: This case underscores a critical blind spot in patient education regarding accessory hygiene. Suction applicators can act as a reservoir for Acanthamoeba and provide a route for inoculation onto the ocular surface. We recommend that these tools undergo regular replacement and be handled with strict no-water protocols. Clinicians should specifically audit and advise on the hygiene of handling tools, particularly in RGP and scleral lens populations.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"17 1","pages":"824-829"},"PeriodicalIF":0.6,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13466464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148721231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0