Case Reports in Ophthalmology最新文献_第3页

Conservative Management of Intraocular Graphite Foreign Body: A Case Report and Literature Review.

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Case Reports in Ophthalmology Pub Date : 2024-11-15 eCollection Date: 2024-01-01 DOI: 10.1159/000542584

Mohamed Shadi Nayeb, Lina Okar, Mahran Zeno, Hashem Abu Serhan

引用次数: 0

Conjunctival Phlyctenule and Nodular Scleritis in a Patient with Previous Herpes Simplex Virus-2 Exposure: Causative Agent or Innocent Bystander? 曾接触过单纯疱疹病毒-2 的患者出现结膜疱疹和结节性巩膜炎：致病因子还是无辜的旁观者？

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Case Reports in Ophthalmology Pub Date : 2024-11-14 eCollection Date: 2024-01-01 DOI: 10.1159/000542076

Shawn Khan, Khushi Saigal, Arash Maleki

{"title":"Conjunctival Phlyctenule and Nodular Scleritis in a Patient with Previous Herpes Simplex Virus-2 Exposure: Causative Agent or Innocent Bystander?","authors":"Shawn Khan, Khushi Saigal, Arash Maleki","doi":"10.1159/000542076","DOIUrl":"10.1159/000542076","url":null,"abstract":"Introduction: Phlyctenular keratoconjunctivitis is an inflammatory condition arising from a type IV hypersensitivity reaction, presenting with inflamed nodules on the conjunctiva and cornea. Scleritis is a severe ocular inflammation linked to systemic diseases, potentially vision threatening, and involving immune responses similar to phlyctenular keratoconjunctivitis. This case report discusses a patient with a history of herpes simplex virus (HSV)-2 infection who primarily developed phlyctenular conjunctivitis and later progressed to nodular scleritis.Case presentation: A 66-year-old female presented with pain, redness, and a foreign body sensation in her left eye for 2 days. Initial treatment for epidemic keratoconjunctivitis with tobramycin-dexamethasone improved her symptoms. However, 3 weeks later, she developed a conjunctival phlyctenule. Diagnostic tests, including blood work and conjunctival swabs, were conducted. While most tests were negative, HSV-2 IgG was positive. The patient failed topical corticosteroid monotherapy; however, she responded to oral valacyclovir. Follow-up examinations showed significant improvement, with resolution of the conjunctival phlyctenule and nodular scleritis, and her best-corrected visual acuity returned to 20/20.Conclusion: This case highlights the importance of considering HSV-2 in atypical presentations of phlyctenular conjunctivitis and scleritis. The patient's response to antiviral therapy underscores the potential role of HSV-2 in such ocular inflammation. Thorough infectious workups and alternative treatment approaches are crucial in managing unconventional cases. Experimental treatments based on laboratory findings can be valuable for patients preferring conservative management, emphasizing the need for close follow-up and personalized care in ocular inflammatory diseases.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"777-783"},"PeriodicalIF":0.5,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11563655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asymptomatic Parasitic Worm Thelazia callipaeda Infection Found during Phacoemulsification: A Case Report.

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Case Reports in Ophthalmology Pub Date : 2024-11-13 eCollection Date: 2024-01-01 DOI: 10.1159/000541509

Xinzhu Chen, Hanmu Guo, Yanting Li, Peirong Lu

{"title":"Asymptomatic Parasitic Worm Thelazia callipaeda Infection Found during Phacoemulsification: A Case Report.","authors":"Xinzhu Chen, Hanmu Guo, Yanting Li, Peirong Lu","doi":"10.1159/000541509","DOIUrl":"https://doi.org/10.1159/000541509","url":null,"abstract":"Introduction: We report a case of asymptomatic Thelazia callipaeda infection discovered incidentally during phacoemulsification cataract surgery in March 2024.Case presentation: A 77-year-old male patient presented with complaints of blurred vision. During a slit-lamp examination, trichiasis was observed, but the patient had no foreign body sensation or itching. He was diagnosed with cataract and underwent phacoemulsification cataract surgery. During the surgery, a white, wriggling worm was discovered in the conjunctival sac and removed. It was later identified as Thelazia callipaeda. The surgical eye was thoroughly washed and received anti-inflammatory medication postoperatively. No recurrence or new symptoms were reported during the 3-month follow-up period.Conclusions: Thelazia callipaeda infection can be asymptomatic and incidentally discovered. A detailed preoperative examination, such as turning over the upper and lower eyelids to check the conjunctival sac, is necessary before the surgery. When a worm is discovered during surgery, it is crucial to remove it completely and thoroughly clean and disinfect the conjunctival sac.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"859-864"},"PeriodicalIF":0.5,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leber Hereditary Optic Neuropathy "Plus" with the m.14487 T>C Mutation as the Causality of Hemidystonia: A Case Report.

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Case Reports in Ophthalmology Pub Date : 2024-11-13 eCollection Date: 2024-01-01 DOI: 10.1159/000542202

Fumio Takano, Kaori Ueda, Norio Chihara, Mina Arai, Mari Sakamoto, Takuji Kurimoto, Yuko Yamada-Nakanishi, Makoto Nakamura

{"title":"Leber Hereditary Optic Neuropathy \"Plus\" with the m.14487 T>C Mutation as the Causality of Hemidystonia: A Case Report.","authors":"Fumio Takano, Kaori Ueda, Norio Chihara, Mina Arai, Mari Sakamoto, Takuji Kurimoto, Yuko Yamada-Nakanishi, Makoto Nakamura","doi":"10.1159/000542202","DOIUrl":"https://doi.org/10.1159/000542202","url":null,"abstract":"Introduction: Leber hereditary optic neuropathy (LHON) complicated with extraocular symptoms is called LHON plus. We describe a case of LHON plus with a rare mutation, which also caused dystonia.Case presentation: An 18-year-old male patient developed symptoms of dystonia at the age of 15 years. Two years later, he noticed decreased visual acuity and central scotoma in the left eye. One month later, the same symptoms occurred in the right eye. Although the optic discs in both eyes revealed mildly redness and edematous change, no abnormal findings were detected on fluorescence fundus angiography and orbital magnetic resonance imaging. Mitochondrial deoxyribonucleic acid (mtDNA) sequencing detected the m.14487 T>C mutation. From clinical course and fundus findings, the case was diagnosed LHON. The optic nerve gradually atrophied and central scotoma remained.Conclusion: The m.14487 T>C mutation is one of the causative mutations in patients with dystonia or Leigh encephalopathy and a minor mutation in patients with LHON. However, in the present case, ocular symptoms were more severe than systematic symptoms and the disease course was consistent with LHON. For the above reasons, this case can be diagnosed as LHON plus. Whole mtDNA sequencing is important in diagnosing LHON if none of the three major mutations are detected.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"852-858"},"PeriodicalIF":0.5,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Unexpected Response of Orbital Retinoblastoma to Inconsistent Systemic Chemotherapy Alone. 眼眶视网膜母细胞瘤对单用持续性全身化疗的意外反应

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Case Reports in Ophthalmology Pub Date : 2024-10-29 eCollection Date: 2024-01-01 DOI: 10.1159/000541776

Khitam F Alhasseny, Haseeb Mahmud, Mohannad Al-Samarraie

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Erratum. 勘误表。

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Case Reports in Ophthalmology Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.1159/000542053

引用次数: 0

A Case of Conjunctival Melanoma Presenting as a Squamous Cell Carcinoma. 一例表现为鳞状细胞癌的结膜黑色素瘤。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1159/000541860

Feliciana Menna, Markus Tschopp, Peter Meyer, Anthia Papazoglou

引用次数: 0

Wide-Excision Choice in Orbital Rhabdomyosarcoma on an 8-Year-Old Patient in a Low-Resource Setting: A Case Report. 在资源匮乏的环境中为一名 8 岁患者选择眼眶横纹肌肉瘤宽切手术：病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1159/000541645

Vera Sumual

{"title":"Wide-Excision Choice in Orbital Rhabdomyosarcoma on an 8-Year-Old Patient in a Low-Resource Setting: A Case Report.","authors":"Vera Sumual","doi":"10.1159/000541645","DOIUrl":"10.1159/000541645","url":null,"abstract":"Introduction: Rhabdomyosarcoma is the most common neoplasm of skeletal myoblast-like cells in children aged 5-8 years. It typically occurs in the head, neck region, genitourinary tract, retroperitoneum, and extremities.Case presentation: An 8-year-old boy complained of a lump under his left eye that he had felt for the past 4 years. Initially small, it gradually grew larger although there were no accompanying symptoms of redness, pain, itching, or eye movement disorders, and no history of trauma. Visual acuity in the left eye was measured at 6/15, with pinhole correction improving to 6/6, while the right eye was 6/6. Intraocular pressure in both eyes was 15 mm Hg. Anterior segment examination of the left eye revealed a mass on the lower eyelid with hard consistency, no erythema, no tenderness, with a flat surface, immobility, and all aspects of the conjunctiva, cornea, pupil, and lens appearing normal. A contrast computed tomography scan showed a solid mass measuring 2.1 × 1.9 × 1.9 cm, suggesting a left inferior eyelid mass. The patient underwent surgical excision of the tumor under general anesthesia. Histopathological examination confirmed the diagnosis of embryonal rhabdomyosarcoma. The patient was scheduled for chemotherapy.Conclusions: Orbital rhabdomyosarcoma typically presents with sudden onset and rapid proptosis, without a history of trauma or respiratory tract infections. The embryonal subtype is the most common and has a better prognosis with combined therapy including surgery, chemotherapy, and radiation. In low-resource settings, early clinical suspicion and thorough physical examination are vital, as limited access to medical tools can complicate management. Treatment should be adapted based on available resources, and regular follow-up is essential to monitor outcomes and ensure optimal care. Any swelling in children should be carefully examined for early detection and effective intervention.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"762-768"},"PeriodicalIF":0.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ophthalmomyiasis Externa: A Case Report in a Tertiary Care Center in Riyadh, Saudi Arabia. 眼肌外膜炎：沙特阿拉伯利雅得一家三级医疗中心的病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1159/000541762

Yasser Ibrahim Althnayan, Omar Saad Alhadlaq

{"title":"Ophthalmomyiasis Externa: A Case Report in a Tertiary Care Center in Riyadh, Saudi Arabia.","authors":"Yasser Ibrahim Althnayan, Omar Saad Alhadlaq","doi":"10.1159/000541762","DOIUrl":"10.1159/000541762","url":null,"abstract":"Introduction: Ophthalmomyiasis externa, which is caused by Oestrus ovis larvae, is a parasitic eye infestation that is prevalent in tropical and subtropical regions. It occurs in rural settings and is associated with risk factors, such as poor sanitation and underlying health conditions. Reports on this disease in Saudi Arabia are rare.Case presentation: A 30-year-old man from a rural area in Riyadh presented with severe left eye irritation and redness after being hit by an insect. Examination revealed seven motile larvae, which were identified as O. ovis, on the conjunctiva. The larvae were mechanically removed, and the patient was treated with topical antibiotics. On follow-up, four additional larvae were found and removed. Symptoms resolved completely, with no further larvae detected on subsequent follow-up.Conclusion: Thorough history and examination are essential for the diagnosis of ophthalmomyiasis, especially in rural areas. Early detection and intervention are vital to prevent serious complications. This case highlighted the importance of awareness among healthcare providers.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"751-756"},"PeriodicalIF":0.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optical Coherence Tomography Abnormalities as the Presenting Sign of an Involuted Sellar/Suprasellar Mass. 光学相干断层扫描异常是髓质/鞍上肿块的先兆。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1159/000541680

Arshia Vosoughi, Jonathan A Micieli

{"title":"Optical Coherence Tomography Abnormalities as the Presenting Sign of an Involuted Sellar/Suprasellar Mass.","authors":"Arshia Vosoughi, Jonathan A Micieli","doi":"10.1159/000541680","DOIUrl":"10.1159/000541680","url":null,"abstract":"Introduction: Pituitary adenomas are benign tumours that can lead to visual loss through compression of the optic chiasm. Patients with pituitary adenomas often present with visual field defects (commonly bitemporal hemianopia), but some may be asymptomatic. In such cases, abnormalities may only be detected through visual field testing or optical coherence tomography (OCT) of the ganglion cell-inner plexiform layer (GCIPL), which may provide a more sensitive method for detecting such abnormalities.Case presentation: A 72-year-old man was incidentally found to have binasal OCT-GCIPL thinning during a routine eye examination. Visual acuity was 20/20 in both eyes. Pupils were equal and reactive without a relative afferent pupillary defect. His Humphrey 24-2 SITA-Fast visual field test results were normal. A magnetic resonance imaging (MRI) revealed a nonenhancing (cystic) sellar/suprasellar mass measuring 1.7 cm craniocaudal by 2.1 cm anteroposteriorly, without associated optic chiasm compression. The lesion was suspected to be either a cystic pituitary adenoma or a Rathke's cleft cyst. Follow-up examination 1 year later showed all findings remained stable, including an unchanged visual acuity, visual fields, OCT-GCIPL, and MRI.Conclusion: The binasal thinning observed on OCT-GCIPL in this case, despite the absence of chiasmal compression on MRI, is suggestive of previous compression of the optic chiasm. This case highlights the potential for spontaneous regression of pituitary adenomas and underscores the importance of OCT-GCIPL as a vital tool for detecting optic chiasmal damage.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"757-761"},"PeriodicalIF":0.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0