Feliciana Menna, Markus Tschopp, Peter Meyer, Anthia Papazoglou
{"title":"A Case of Conjunctival Melanoma Presenting as a Squamous Cell Carcinoma.","authors":"Feliciana Menna, Markus Tschopp, Peter Meyer, Anthia Papazoglou","doi":"10.1159/000541860","DOIUrl":"10.1159/000541860","url":null,"abstract":"<p><strong>Introduction: </strong>Conjunctival melanoma (CM) is a rare but potentially lethal ocular malignancy that arises from melanocytes in the conjunctiva. Its clinical presentation can mimic other more common conjunctival lesions, such as squamous cell carcinoma (SCC), leading to diagnostic challenges.</p><p><strong>Case presentation: </strong>We present a case of CM initially misdiagnosed as conjunctival SCC due to overlapping clinical features.</p><p><strong>Conclusion: </strong>CM presenting as nonpigmented, conjunctival tumor is a diagnostic challenge. Clinicians should maintain a high index of suspicion for conjunctival melanocytic or amelanotic lesions, particularly those with atypical features.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"742-750"},"PeriodicalIF":0.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wide-Excision Choice in Orbital Rhabdomyosarcoma on an 8-Year-Old Patient in a Low-Resource Setting: A Case Report.","authors":"Vera Sumual","doi":"10.1159/000541645","DOIUrl":"10.1159/000541645","url":null,"abstract":"<p><strong>Introduction: </strong>Rhabdomyosarcoma is the most common neoplasm of skeletal myoblast-like cells in children aged 5-8 years. It typically occurs in the head, neck region, genitourinary tract, retroperitoneum, and extremities.</p><p><strong>Case presentation: </strong>An 8-year-old boy complained of a lump under his left eye that he had felt for the past 4 years. Initially small, it gradually grew larger although there were no accompanying symptoms of redness, pain, itching, or eye movement disorders, and no history of trauma. Visual acuity in the left eye was measured at 6/15, with pinhole correction improving to 6/6, while the right eye was 6/6. Intraocular pressure in both eyes was 15 mm Hg. Anterior segment examination of the left eye revealed a mass on the lower eyelid with hard consistency, no erythema, no tenderness, with a flat surface, immobility, and all aspects of the conjunctiva, cornea, pupil, and lens appearing normal. A contrast computed tomography scan showed a solid mass measuring 2.1 × 1.9 × 1.9 cm, suggesting a left inferior eyelid mass. The patient underwent surgical excision of the tumor under general anesthesia. Histopathological examination confirmed the diagnosis of embryonal rhabdomyosarcoma. The patient was scheduled for chemotherapy.</p><p><strong>Conclusions: </strong>Orbital rhabdomyosarcoma typically presents with sudden onset and rapid proptosis, without a history of trauma or respiratory tract infections. The embryonal subtype is the most common and has a better prognosis with combined therapy including surgery, chemotherapy, and radiation. In low-resource settings, early clinical suspicion and thorough physical examination are vital, as limited access to medical tools can complicate management. Treatment should be adapted based on available resources, and regular follow-up is essential to monitor outcomes and ensure optimal care. Any swelling in children should be carefully examined for early detection and effective intervention.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"762-768"},"PeriodicalIF":0.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ophthalmomyiasis Externa: A Case Report in a Tertiary Care Center in Riyadh, Saudi Arabia.","authors":"Yasser Ibrahim Althnayan, Omar Saad Alhadlaq","doi":"10.1159/000541762","DOIUrl":"10.1159/000541762","url":null,"abstract":"<p><strong>Introduction: </strong>Ophthalmomyiasis externa, which is caused by <i>Oestrus ovis</i> larvae, is a parasitic eye infestation that is prevalent in tropical and subtropical regions. It occurs in rural settings and is associated with risk factors, such as poor sanitation and underlying health conditions. Reports on this disease in Saudi Arabia are rare.</p><p><strong>Case presentation: </strong>A 30-year-old man from a rural area in Riyadh presented with severe left eye irritation and redness after being hit by an insect. Examination revealed seven motile larvae, which were identified as <i>O</i>. <i>ovis</i>, on the conjunctiva. The larvae were mechanically removed, and the patient was treated with topical antibiotics. On follow-up, four additional larvae were found and removed. Symptoms resolved completely, with no further larvae detected on subsequent follow-up.</p><p><strong>Conclusion: </strong>Thorough history and examination are essential for the diagnosis of ophthalmomyiasis, especially in rural areas. Early detection and intervention are vital to prevent serious complications. This case highlighted the importance of awareness among healthcare providers.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"751-756"},"PeriodicalIF":0.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical Coherence Tomography Abnormalities as the Presenting Sign of an Involuted Sellar/Suprasellar Mass.","authors":"Arshia Vosoughi, Jonathan A Micieli","doi":"10.1159/000541680","DOIUrl":"10.1159/000541680","url":null,"abstract":"<p><strong>Introduction: </strong>Pituitary adenomas are benign tumours that can lead to visual loss through compression of the optic chiasm. Patients with pituitary adenomas often present with visual field defects (commonly bitemporal hemianopia), but some may be asymptomatic. In such cases, abnormalities may only be detected through visual field testing or optical coherence tomography (OCT) of the ganglion cell-inner plexiform layer (GCIPL), which may provide a more sensitive method for detecting such abnormalities.</p><p><strong>Case presentation: </strong>A 72-year-old man was incidentally found to have binasal OCT-GCIPL thinning during a routine eye examination. Visual acuity was 20/20 in both eyes. Pupils were equal and reactive without a relative afferent pupillary defect. His Humphrey 24-2 SITA-Fast visual field test results were normal. A magnetic resonance imaging (MRI) revealed a nonenhancing (cystic) sellar/suprasellar mass measuring 1.7 cm craniocaudal by 2.1 cm anteroposteriorly, without associated optic chiasm compression. The lesion was suspected to be either a cystic pituitary adenoma or a Rathke's cleft cyst. Follow-up examination 1 year later showed all findings remained stable, including an unchanged visual acuity, visual fields, OCT-GCIPL, and MRI.</p><p><strong>Conclusion: </strong>The binasal thinning observed on OCT-GCIPL in this case, despite the absence of chiasmal compression on MRI, is suggestive of previous compression of the optic chiasm. This case highlights the potential for spontaneous regression of pituitary adenomas and underscores the importance of OCT-GCIPL as a vital tool for detecting optic chiasmal damage.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"757-761"},"PeriodicalIF":0.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eszter Szalai, Michael W Belin, Zsuzsanna Szijártó, Adrienne Csutak
{"title":"Visual Recovery and Endothelial Repopulation after DMEK Graft Removal and Vitrectomy for Late Endophthalmitis: A Case Report.","authors":"Eszter Szalai, Michael W Belin, Zsuzsanna Szijártó, Adrienne Csutak","doi":"10.1159/000541644","DOIUrl":"https://doi.org/10.1159/000541644","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to report a unique case with excellent clinical outcomes after late endophthalmitis following Descemet's membrane endothelial keratoplasty (DMEK) surgery requiring donor graft removal without replacement.</p><p><strong>Case presentation: </strong>A 67-year-old female with a prior ocular history of bilateral cataract surgery, Fuchs endothelial dystrophy, and pseudophakic DMEK in the left eye presented with endophthalmitis 2 months after keratoplasty. DMEK graft removal without replacement with an intracameral washout, pars plana vitrectomy, intracameral, and intravitreal antibiotics resulted in an excellent visual outcome (20/25).</p><p><strong>Conclusion: </strong>This is a unique case of late endophthalmitis following DMEK surgery requiring graft removal and pars plana vitrectomy with excellent visual recovery without donor replacement.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"736-741"},"PeriodicalIF":0.5,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11501103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142516304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Successful Case of Intervention for Traumatic Central Retinal Artery Occlusion.","authors":"Mohsen Pourazizi, Alireza Dehghani, Sepehr Karbasi, Elham Rahmanipour","doi":"10.1159/000541498","DOIUrl":"https://doi.org/10.1159/000541498","url":null,"abstract":"<p><strong>Introduction: </strong>Central retinal artery occlusion (CRAO) is a serious ophthalmic disease predominantly affecting older individuals with cardiovascular risk factors. While most cases are attributed to thrombus formation from atheromatous plaques or cardioembolic events, trauma-related CRAO, though rare, presents unique diagnostic and therapeutic challenges.</p><p><strong>Case presentation: </strong>A 47-year-old woman with multiple controlled comorbidities presented to the emergency department with right eye pain and erythema following a traumatic injury involving a knitting needle. Initial examinations revealed hand motion visual acuity in the right eye, a partial thickness scleral laceration, and conjunctival laceration, which were surgically repaired. Postoperatively, she developed blurred vision, hyphema, and signs of CRAO, prompting anterior chamber paracentesis. OCT imaging revealed marked hyperreflectivity and thickening of the inner retinal layers, indicating significant ischemic damage. Despite normal inflammatory markers, the patient's visual acuity gradually improved from 2/10 to 5/10 with intervention and eventually reached 10/10 with myopic correction after the hyphema resolved.</p><p><strong>Conclusion: </strong>The case emphasizes the necessity of early recognition and intervention in managing traumatic CRAO to mitigate irreversible retinal damage. It underscores the need for enhanced diagnostic and therapeutic strategies as understanding the condition's pathophysiology advances.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"730-735"},"PeriodicalIF":0.5,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Achia Nemet, Itai Hacker, Chani Topf-Olivestone, Ran Svirsky, Joseph Pikkel, Michael Kinori
{"title":"Wilson's Disease and Nevus of Ota in a Child: A Case Report.","authors":"Achia Nemet, Itai Hacker, Chani Topf-Olivestone, Ran Svirsky, Joseph Pikkel, Michael Kinori","doi":"10.1159/000541119","DOIUrl":"https://doi.org/10.1159/000541119","url":null,"abstract":"<p><strong>Introduction: </strong>Wilson's disease is a rare autosomal recessive disorder that disrupts copper metabolism. It presents with distinctive ocular manifestations. Oculodermal melanosis, commonly referred to as nevus of Ota, is a painless condition characterized by hyperpigmentation in and around the eye. In this case report, we describe the unique occurrence of both conditions in this pediatric patient.</p><p><strong>Case presentation: </strong>A 10-year-old girl exhibited classic ocular signs associated with Wilson's disease, including Kayser-Fleischer rings and sunflower-type cataracts. Additionally, she displayed unilateral confluent gray-blue hyperpigmentation consistent with a nevus of Ota. As of now, the patient remains asymptomatic, with preserved visual acuity.</p><p><strong>Conclusions: </strong>To the best of our knowledge, this case represents the first report of nevus of Ota in a child diagnosed with Wilson's disease.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"724-728"},"PeriodicalIF":0.5,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142550046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calciphylaxis Mimicking Giant Cell Arteritis: A Case Report.","authors":"Nada Alyousef, Wael A Alsakran, Azza Maktabi","doi":"10.1159/000541410","DOIUrl":"https://doi.org/10.1159/000541410","url":null,"abstract":"<p><strong>Introduction: </strong>Calciphylaxis is a condition that causes vascular calcification and intimal proliferation with thrombotic occlusion of small-to-medium-sized vessels.</p><p><strong>Case presentation: </strong>We describe a case of a 64-year-old woman who presented with a clinical picture that was suggestive of anterior arteritic ischemic optic neuropathy due to giant cell arteritis (GCA), but was found to have calciphylaxis confirmed by histologic examination. When calciphylaxis affects the blood supply to the eye, commonly it causes sudden vision loss, pallid optic disk edema, and a relative afferent pupillary defect, all of which were observed in our patient.</p><p><strong>Conclusion: </strong>There is no known cure for calciphylaxis, while in GCA, high-dose corticosteroid therapy is essential to prevent involvement of the contralateral eye. As the management approaches for these two diseases are different, it is important to have performed a thorough clinical examination along with detailed histopathological testing to rule out calciphylaxis of the temporal artery in patients suspected to have GCA.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"717-723"},"PeriodicalIF":0.5,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rem Aziz, Cody Lo, James T Denstedt, Bernard Hurley
{"title":"Working under Pressure: Scleroderma Presenting with Bilateral Exudative Retinal Detachment in the Context of Scleroderma Renal Crisis: A Case Report.","authors":"Rem Aziz, Cody Lo, James T Denstedt, Bernard Hurley","doi":"10.1159/000530973","DOIUrl":"https://doi.org/10.1159/000530973","url":null,"abstract":"<p><p>This is an observational case report to detail a novel case of scleroderma renal crisis presenting as bilateral exudative retinal detachments in a patient with newly diagnosed systemic sclerosis. An otherwise healthy 58-year-old female presented primarily with vision complaints and was found to have malignant hypertension (230/120 mm Hg) and bilateral exudative retinal detachment on dilated fundus examination and macular OCT scan. Further history revealed sclerodactyly, mild dysphagia, and dyspnea. She was diagnosed with diffuse systemic sclerosis and Sjogren's syndrome complicated by an episode of scleroderma renal crisis based on initial medical workup. She was admitted to intensive care for management of refractory hypertension with IV antihypertensive therapy. Three months after treatment, her visual symptoms and ocular findings resolved. The presence of exudative retinal detachment among other signs of hypertensive retinopathy warrants thorough systemic screening for underlying causes of malignant hypertension, including systemic sclerosis. Treatment of the underlying disease with urgent antihypertensive therapy resolved the exudative retinal detachments and restored vision in the case of a scleroderma renal crisis.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"710-716"},"PeriodicalIF":0.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}