Case Reports in Ophthalmology最新文献_第6页

A Case Report of Intravitreal Aflibercept for Iris Metastasis from Small Cell Lung Carcinoma with Neovascular Glaucoma. 小细胞肺癌伴新生血管性青光眼虹膜转移玻璃体内注射阿非利赛普1例。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1159/000544159

Hitoshi Goto, Kyrie Hirakata, Kenji Nakamoto, Fumiki Okamoto, Junko Hori

{"title":"A Case Report of Intravitreal Aflibercept for Iris Metastasis from Small Cell Lung Carcinoma with Neovascular Glaucoma.","authors":"Hitoshi Goto, Kyrie Hirakata, Kenji Nakamoto, Fumiki Okamoto, Junko Hori","doi":"10.1159/000544159","DOIUrl":"https://doi.org/10.1159/000544159","url":null,"abstract":"Introduction: Metastatic iris tumors from lung cancer are uncommon and challenging to diagnose. As lung cancer treatments improve, life expectancy increases, potentially leading to more cases of metastasis. These tumors often cause neovascular glaucoma, making intraocular pressure (IOP) management crucial, especially in terminal-stage patients.Case presentation: A 65-year-old man with small cell lung carcinoma (SCLC) presented with right ocular pain and blurred vision. His right IOP was 55 mm Hg, and examination revealed anterior chamber cells, multiple grayish-white iris masses, and right iris neovascularization. Anterior chamber fluid cytology confirmed the diagnosis of metastatic iris tumors from SCLC. Despite treatment with topical eye drops, oral acetazolamide, and intravenous hypertonic mannitol, the IOP remained poorly controlled. Intravitreal aflibercept was subsequently administered into his right eye for neovascular glaucoma. Neovascular glaucoma disappeared rapidly, but IOP did not improve. However, intravenous infusion of hypertonic mannitol was no longer required, and the complaints of nausea associated with IOP decreased. Although this patient died 4 months after the initial visit due to multiple metastases of SCLC, the intravitreal aflibercept was effective in shrinking the iris tumor size and lowering IOP in the terminal phase of the disease.Conclusion: This is the first reported use of intravitreal aflibercept for SCLC metastases to the iris. While the prognosis of patients with metastatic iris tumors remains poor, intravitreal aflibercept injections show potential in reducing iris tumor size and lowering IOP. Although not curative, this therapeutic approach may play a significant role in the symptom management of these patients.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"215-220"},"PeriodicalIF":0.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11919313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Choroidal Thickening and Outer Retinal Alterations in Vitamin A Deficiency: A Case Report. 脉络膜增厚和外视网膜改变维生素A缺乏：一个病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1159/000544701

Damian Jaggi, Joel-Benjamin Lincke, Florian M Heussen, Jan D Unterlauft, Martin S Zinkernagel, Lieselotte E Berger

{"title":"Choroidal Thickening and Outer Retinal Alterations in Vitamin A Deficiency: A Case Report.","authors":"Damian Jaggi, Joel-Benjamin Lincke, Florian M Heussen, Jan D Unterlauft, Martin S Zinkernagel, Lieselotte E Berger","doi":"10.1159/000544701","DOIUrl":"10.1159/000544701","url":null,"abstract":"Introduction: Retinal alterations in vitamin A deficiency have been described. The purpose of this study was to report a case of retinal alterations and choroidal thickening due to proven vitamin A deficiency.Case presentation: We report a case of a 39-year-old woman who presented with progressing nyctalopia and mildly reduced visual acuity over a period of 1-2 years, despite being on oral vitamin A supplementation, following a history of gastric bypass and biliopancreatic diversion surgeries many years ago. Vitamin A levels were severely reduced (<0.1 µmol/L, reference range: 1.05-2.08 µmol/L). The outer retinal layers exhibited structural alterations and a reduction in thickness, while choroidal thickness was increased. The electroretinogram showed complete depletion of scotopic responses and a mild reduction in photopic responses. After intravenous vitamin A supplementation, complete resolution of both functional and structural changes was achieved.Conclusion: This case highlights the importance of considering vitamin A deficiency even in patients receiving ongoing oral vitamin A supplementation, particularly if symptoms and clinical findings suggest its presence. Choroidal thickening and outer retinal thinning may provide further insights into the pathophysiology of this condition in future analyses.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"207-214"},"PeriodicalIF":0.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iatrogenic Cushing Syndrome and Secondary Adrenal Insufficiency in a Child due to Topical Ocular Corticosteroids: A Case Report. 医源性库欣综合征和继发性肾上腺功能不全的儿童由于局部眼皮质类固醇：一个病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.1159/000543908

Joana Santos-Oliveira, Luís Torrão, Sónia Torres-Costa, Marta Silva, Ana Catarina Pedrosa, Joana Araújo, Luís Figueira, Cláudia Oliveira-Ferreira

{"title":"Iatrogenic Cushing Syndrome and Secondary Adrenal Insufficiency in a Child due to Topical Ocular Corticosteroids: A Case Report.","authors":"Joana Santos-Oliveira, Luís Torrão, Sónia Torres-Costa, Marta Silva, Ana Catarina Pedrosa, Joana Araújo, Luís Figueira, Cláudia Oliveira-Ferreira","doi":"10.1159/000543908","DOIUrl":"https://doi.org/10.1159/000543908","url":null,"abstract":"Introduction: Iatrogenic Cushing syndrome (ICS) can be caused by synthetic glucocorticoids administered through various routes. ICS caused by corticosteroid eye drops is an exceptional event, being more frequent in pediatric age. Herein, we describe a case of ICS associated with secondary adrenal insufficiency (SAI) caused by ocular topical corticosteroid treatment.Case presentation: An 11-year-old girl was referred to our ocular inflammation department due to idiopathic, chronic, non-hypertensive, non-granulomatous bilateral anterior uveitis, treated with topical dexamethasone (eye drops, 1 mg/mL) for 1 year. During the past year, the child and her mother observed a gradual change in her physical appearance, particularly noting the development of a cushingoid facial appearance. Laboratory data revealed morning serum adrenocorticotropic hormone (ACTH) of 3.6 ng/L (7.2-63.3) and morning serum cortisol of 0.20 μg/dL (6.2-19.4). She was treated with methotrexate (15 mg/week, orally), and the topical corticosteroid regimen was progressively tapered and discontinued after 3 months. Nine months after the patient discontinued corticosteroid eye drops, her cushingoid face disappeared, and her laboratory data improved. Regarding the ophthalmological examination, the uveitis remained in remission with methotrexate, with no new episodes of intraocular inflammation.Conclusion: Although rare, ophthalmologists must be aware of ICS and SAI and prioritize using the least potent corticosteroid for the shortest duration necessary. Additionally, clinicians should avoid abrupt cessation of long-term corticosteroid therapy as this can precipitate an adrenal crisis in the presence of adrenal insufficiency.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"194-201"},"PeriodicalIF":0.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11908803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valsalva-Induced Orbital and Subcutaneous Periorbital Emphysema Secondary to Lamina Papyracea Dehiscence: A Case Report. 缬草诱导的继发于纸莎草膜破裂的眼眶及皮下眼眶周围肺气肿1例。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1159/000544098

Stuti Misty Tanya, Merve Kulbay, Femida Kherani, Marc B Mydlarski

{"title":"Valsalva-Induced Orbital and Subcutaneous Periorbital Emphysema Secondary to Lamina Papyracea Dehiscence: A Case Report.","authors":"Stuti Misty Tanya, Merve Kulbay, Femida Kherani, Marc B Mydlarski","doi":"10.1159/000544098","DOIUrl":"https://doi.org/10.1159/000544098","url":null,"abstract":"Introduction: Pneumo-orbit and periorbital subcutaneous emphysema secondary to defects in the sinus wall have been well described in the context of traumatic or surgical sequelae. However, these conditions may rarely occur atraumatically in the setting of an idiopathic or congenital sinus wall dehiscence, with a risk for orbital compartment syndrome and irreversible vision loss. We describe a case of idiopathic lamina papyracea dehiscence with resultant pneumo-orbit and elevated intraocular pressure.Case presentation: A 28-year-old man experienced a sudden onset of unilateral orbital and subcutaneous periorbital emphysema following Valsalva maneuver. He had unilateral subcutaneous emphysema, crepitus, violaceous discoloration of the lids, and chemosis of the palpebral conjunctiva. Visual acuity was intact, and intraocular pressure was mildly elevated. Imaging showed an idiopathic lamina papyracea dehiscence. The patient was advised of sinus precautions with uneventful spontaneous resolution and no visual sequelae.Conclusion: Lamina papyracea dehiscence predisposes to spontaneous Valsalva-induced orbital or periorbital emphysema with a risk of elevated intraocular pressure, optic neuropathy, and vision loss; prompt recognition and early management can prevent vision-threatening sequelae.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"202-206"},"PeriodicalIF":0.5,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11908810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement in Dry Age-Related Macular Degeneration with Photobiomodulation. 光生物调节改善干性老年性黄斑变性。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.1159/000543971

Patrick Xiang Ji, Lauren Pickel, Alan R Berger, Nirojini Sivachandran

{"title":"Improvement in Dry Age-Related Macular Degeneration with Photobiomodulation.","authors":"Patrick Xiang Ji, Lauren Pickel, Alan R Berger, Nirojini Sivachandran","doi":"10.1159/000543971","DOIUrl":"https://doi.org/10.1159/000543971","url":null,"abstract":"Introduction: This case report describes a finding of dramatic improvement in drusen volume and visual acuity in a 73-year-old patient diagnosed with dry age-related macular degeneration (AMD) undergoing daily home photobiomodulation alongside AREDS-2 supplements.Case presentation: This is a retrospective review of a case presentation from 2023 to 2024. After 8 months of continuous home photobiomodulation, the patient's visual acuity improved from 20/30 to 20/20 in the left eye while the right eye stabilized at 20/25. The outer retina was preserved without signs of geographic atrophy, with a robust reduction in the total number and volume of drusen in both eyes, left greater than right, as shown with optical coherence tomography macular cross-sectional scans.Conclusions: These findings support that photobiomodulation has the potential to improve the management of dry AMD and the overall quality of life, consistent with phase III clinical trials. Future studies are warranted to further establish optimized protocols for broader clinical implementation.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"155-162"},"PeriodicalIF":0.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progressive Retinal Degeneration and Juvenile Nephronophthisis in a Patient with Autosomal Recessive Ciliopathy: A Case Report. 常染色体隐性纤毛病患者进行性视网膜变性和幼年肾病1例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-02-03 eCollection Date: 2025-01-01 DOI: 10.1159/000543419

Jakob M Pericak, Eric K Chin, David R P Almeida

{"title":"Progressive Retinal Degeneration and Juvenile Nephronophthisis in a Patient with Autosomal Recessive Ciliopathy: A Case Report.","authors":"Jakob M Pericak, Eric K Chin, David R P Almeida","doi":"10.1159/000543419","DOIUrl":"10.1159/000543419","url":null,"abstract":"Introduction: Inherited retinal diseases, particularly ciliopathies, often lead to irreversible blindness and are frequently accompanied by systemic manifestations such as nephronophthisis. Current treatment options are limited, necessitating the exploration of supplementary strategies to slow disease progression.Case presentation: We present a rare case from a retinal surgery clinic involving a 30-year-old male with autosomal recessive retinitis pigmentosa (ARRP) and juvenile nephronophthisis. Comprehensive ocular and genetic evaluations were conducted, followed by the implementation of nutritional interventions aimed at mitigating multi-systemic effects. Genetic testing revealed pathogenic variants in CEP83, PCARE, and VPS13B genes, confirming the diagnosis of ARRP. Nutritional strategies, including omega-3 fatty acids, antioxidants, and tailored dietary modifications for renal health, were integrated alongside standard medical care. These interventions contributed to the stabilization of retinal degeneration and improved management of end-stage renal disease.Conclusion: Integrating personalized nutritional strategies into the management of ciliopathies can enhance patient out-comes by addressing both ocular and systemic manifestations. These findings underscore the need for policy development around nutritional education and support for patients with inherited ciliopathies.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"143-148"},"PeriodicalIF":0.5,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Road Less Traveled: Ciliary Sulcus Implantation of the Preserflo MicroShunt. 少有人走的路：Preserflo微分流器睫状沟植入。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-01-30 eCollection Date: 2025-01-01 DOI: 10.1159/000543219

Meishar Meisel, Eran Berkowitz, Avi Schwalb, Beatrice Tiosano

{"title":"The Road Less Traveled: Ciliary Sulcus Implantation of the Preserflo MicroShunt.","authors":"Meishar Meisel, Eran Berkowitz, Avi Schwalb, Beatrice Tiosano","doi":"10.1159/000543219","DOIUrl":"10.1159/000543219","url":null,"abstract":"Introduction: Herein, we report on the option and clinical advantage of the Preserflo MicroShunt insertion into the posterior chamber ciliary sulcus in a patient with advanced pseudoexfoliation glaucoma at a high risk of corneal decompensation.Case presentation: We describe a 64-year-old advanced pseudoexfoliation glaucoma patient who despite maximal tolerated medical therapy and two failed glaucoma surgeries, still suffered from uncontrolled intraocular pressure (IOP) of 36 mm Hg in his left eye. The patient underwent the implantation of the Preserflo MicroShunt. The shunt was placed nasally into an area of unscarred conjunctiva, with the anterior part of the shunt inserted into the ciliary sulcus. Postoperatively, the patient's IOP dropped to 6 mm Hg on the first day and stabilized at 11 mm Hg at the 6-month mark. An elevated, posteriorly located bleb was observed, and the patient no longer required additional topical medications. Endothelial cell (EC) count remained stable with no signs of corneal edema. The patient did not experience any serious postoperative complications.Conclusion: Implantation of the Preserflo MicroShunt into the ciliary sulcus appears to be a viable option for patients at high risk of corneal decompensation, hence, offering effective IOP control while minimizing EC loss. Further studies with larger patient groups are warranted to better evaluate the safety and efficacy of this technique.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"68-73"},"PeriodicalIF":0.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report. 标准剂量头孢呋辛腹腔注射致中毒性黄斑病变1例。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-01-28 eCollection Date: 2025-01-01 DOI: 10.1159/000543837

Maria E Pantelidou, Stylianos Bebis, Elias P Pantelidis, Tryfon Rotsos

引用次数: 0

Bilateral Paraneoplastic Optic Neuropathy as the First Presentation of Preclinical Small Cell Lung Cancer: Case Report. 双侧副肿瘤视神经病变作为临床前小细胞肺癌的首次表现：病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-01-24 eCollection Date: 2025-01-01 DOI: 10.1159/000543516

Sara Sharif, Dhruv Gor, Haider Shah, Nima Ghadiri

{"title":"Bilateral Paraneoplastic Optic Neuropathy as the First Presentation of Preclinical Small Cell Lung Cancer: Case Report.","authors":"Sara Sharif, Dhruv Gor, Haider Shah, Nima Ghadiri","doi":"10.1159/000543516","DOIUrl":"10.1159/000543516","url":null,"abstract":"Introduction: Paraneoplastic optic neuropathy (PON) is a rare immune-mediated optic neuropathy, secondary to an underlying malignancy. This report describes a rare case of bilateral PON as the initial manifestation in a 77-year-old male, leading to the early detection and treatment of preclinical small cell lung cancer (SCLC).Case presentation: The patient initially presented with incidental bilateral disc swelling but was asymptomatic, with preserved visual function. Initial investigations, including orbito-cranial imaging, lumbar puncture, temporal artery ultrasound, and serological testing, were inconclusive. Six weeks later, the patient had persistent disc swelling with compromised bilateral visual function and was commenced on oral steroids. Further diagnostic workup identified paraneoplastic antibodies (anti-CV2/CRMP-5 and anti-Hu) and PET scan findings consistent with a nodular SCLC. Following biopsy confirmation, the patient underwent carboplatin and etoposide chemotherapy, followed by radiotherapy. Initial oral steroids, prior to cancer treatment, resulted in resolution of optic disc swelling and stabilization of visual function.Conclusion: This case underscores the importance of a systematic approach to optic neuropathies where an initial diagnosis is not found, revisiting diagnostic pathways when initial findings remain ambiguous, and consideration of PON as a differential - even in the absence of known malignancy or typical cancer symptoms. Timely recognition allows for early intervention, improving patient outcomes. This report contributes to the limited literature on PON and highlights the role of multidisciplinary care in managing complex cases involving paraneoplastic syndromes.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"163-170"},"PeriodicalIF":0.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Diathermy-Induced Corneal Burn following Upper Eyelid Blepharoplasty with Multilayer Amniotic Membrane Transplantation: A Case Report and Review of the Literature. 多层羊膜移植上睑成形术后透热性角膜烧伤的处理：1例报告及文献复习。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2025-01-24 eCollection Date: 2025-01-01 DOI: 10.1159/000543760

Konstantina Bachtalia, Sotiria Palioura

{"title":"Management of Diathermy-Induced Corneal Burn following Upper Eyelid Blepharoplasty with Multilayer Amniotic Membrane Transplantation: A Case Report and Review of the Literature.","authors":"Konstantina Bachtalia, Sotiria Palioura","doi":"10.1159/000543760","DOIUrl":"10.1159/000543760","url":null,"abstract":"Introduction: Thermal injuries associated with cosmetic eyelid surgery can significantly impair corneal integrity, potentially leading to vision loss. Conventional management, including bandage contact lens use, topical steroids, lubrication, autologous serum tears, and vitamin C, plays a crucial role in preventing long-term complications. This case report explores the potential benefits of multilayer amniotic membrane transplantation (AMT) as an adjunct to standard therapy for treating diathermy-associated corneal burns. Review of the literature advocates the beneficial effects of supplementary AMT in managing thermal corneal trauma.Case description: A 75-year-old man presented with unilateral diathermy-associated corneal laceration superior to the visual axis following cosmetic blepharoplasty. Vision had deteriorated from his baseline 20/30 to 20/125 postoperatively. Intervention involved multilayer AMT alongside standard care, including topical steroids and antibiotics, oral doxycycline, and vitamin C. Postoperative course was monitored with anterior segment optical coherence tomography (AS-OCT) imaging. By 3 months, complete corneal healing and restoration of baseline visual acuity were achieved.Conclusion: This is the first documented case of multilayer AMT as an effective supplement to conventional management of diathermy-associated corneal injury. While AMTs unique properties likely contributed to corneal healing and visual recovery, the results should be interpreted in the context of a multimodal therapeutic approach.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"133-142"},"PeriodicalIF":0.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0