Case Reports in Ophthalmology最新文献

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Valsalva-Induced Orbital and Subcutaneous Periorbital Emphysema Secondary to Lamina Papyracea Dehiscence: A Case Report. 缬草诱导的继发于纸莎草膜破裂的眼眶及皮下眼眶周围肺气肿1例。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1159/000544098
Stuti Misty Tanya, Merve Kulbay, Femida Kherani, Marc B Mydlarski
{"title":"Valsalva-Induced Orbital and Subcutaneous Periorbital Emphysema Secondary to Lamina Papyracea Dehiscence: A Case Report.","authors":"Stuti Misty Tanya, Merve Kulbay, Femida Kherani, Marc B Mydlarski","doi":"10.1159/000544098","DOIUrl":"https://doi.org/10.1159/000544098","url":null,"abstract":"<p><strong>Introduction: </strong>Pneumo-orbit and periorbital subcutaneous emphysema secondary to defects in the sinus wall have been well described in the context of traumatic or surgical sequelae. However, these conditions may rarely occur atraumatically in the setting of an idiopathic or congenital sinus wall dehiscence, with a risk for orbital compartment syndrome and irreversible vision loss. We describe a case of idiopathic lamina papyracea dehiscence with resultant pneumo-orbit and elevated intraocular pressure.</p><p><strong>Case presentation: </strong>A 28-year-old man experienced a sudden onset of unilateral orbital and subcutaneous periorbital emphysema following Valsalva maneuver. He had unilateral subcutaneous emphysema, crepitus, violaceous discoloration of the lids, and chemosis of the palpebral conjunctiva. Visual acuity was intact, and intraocular pressure was mildly elevated. Imaging showed an idiopathic lamina papyracea dehiscence. The patient was advised of sinus precautions with uneventful spontaneous resolution and no visual sequelae.</p><p><strong>Conclusion: </strong>Lamina papyracea dehiscence predisposes to spontaneous Valsalva-induced orbital or periorbital emphysema with a risk of elevated intraocular pressure, optic neuropathy, and vision loss; prompt recognition and early management can prevent vision-threatening sequelae.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"202-206"},"PeriodicalIF":0.5,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11908810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement in Dry Age-Related Macular Degeneration with Photobiomodulation. 光生物调节改善干性老年性黄斑变性。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.1159/000543971
Patrick Xiang Ji, Lauren Pickel, Alan R Berger, Nirojini Sivachandran
{"title":"Improvement in Dry Age-Related Macular Degeneration with Photobiomodulation.","authors":"Patrick Xiang Ji, Lauren Pickel, Alan R Berger, Nirojini Sivachandran","doi":"10.1159/000543971","DOIUrl":"https://doi.org/10.1159/000543971","url":null,"abstract":"<p><strong>Introduction: </strong>This case report describes a finding of dramatic improvement in drusen volume and visual acuity in a 73-year-old patient diagnosed with dry age-related macular degeneration (AMD) undergoing daily home photobiomodulation alongside AREDS-2 supplements.</p><p><strong>Case presentation: </strong>This is a retrospective review of a case presentation from 2023 to 2024. After 8 months of continuous home photobiomodulation, the patient's visual acuity improved from 20/30 to 20/20 in the left eye while the right eye stabilized at 20/25. The outer retina was preserved without signs of geographic atrophy, with a robust reduction in the total number and volume of drusen in both eyes, left greater than right, as shown with optical coherence tomography macular cross-sectional scans.</p><p><strong>Conclusions: </strong>These findings support that photobiomodulation has the potential to improve the management of dry AMD and the overall quality of life, consistent with phase III clinical trials. Future studies are warranted to further establish optimized protocols for broader clinical implementation.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"155-162"},"PeriodicalIF":0.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progressive Retinal Degeneration and Juvenile Nephronophthisis in a Patient with Autosomal Recessive Ciliopathy: A Case Report. 常染色体隐性纤毛病患者进行性视网膜变性和幼年肾病1例报告。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-02-03 eCollection Date: 2025-01-01 DOI: 10.1159/000543419
Jakob M Pericak, Eric K Chin, David R P Almeida
{"title":"Progressive Retinal Degeneration and Juvenile Nephronophthisis in a Patient with Autosomal Recessive Ciliopathy: A Case Report.","authors":"Jakob M Pericak, Eric K Chin, David R P Almeida","doi":"10.1159/000543419","DOIUrl":"10.1159/000543419","url":null,"abstract":"<p><strong>Introduction: </strong>Inherited retinal diseases, particularly ciliopathies, often lead to irreversible blindness and are frequently accompanied by systemic manifestations such as nephronophthisis. Current treatment options are limited, necessitating the exploration of supplementary strategies to slow disease progression.</p><p><strong>Case presentation: </strong>We present a rare case from a retinal surgery clinic involving a 30-year-old male with autosomal recessive retinitis pigmentosa (ARRP) and juvenile nephronophthisis. Comprehensive ocular and genetic evaluations were conducted, followed by the implementation of nutritional interventions aimed at mitigating multi-systemic effects. Genetic testing revealed pathogenic variants in <i>CEP83</i>, <i>PCARE</i>, and <i>VPS13B</i> genes, confirming the diagnosis of ARRP. Nutritional strategies, including omega-3 fatty acids, antioxidants, and tailored dietary modifications for renal health, were integrated alongside standard medical care. These interventions contributed to the stabilization of retinal degeneration and improved management of end-stage renal disease.</p><p><strong>Conclusion: </strong>Integrating personalized nutritional strategies into the management of ciliopathies can enhance patient out-comes by addressing both ocular and systemic manifestations. These findings underscore the need for policy development around nutritional education and support for patients with inherited ciliopathies.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"143-148"},"PeriodicalIF":0.5,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Road Less Traveled: Ciliary Sulcus Implantation of the Preserflo MicroShunt. 少有人走的路:Preserflo微分流器睫状沟植入。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-01-30 eCollection Date: 2025-01-01 DOI: 10.1159/000543219
Meishar Meisel, Eran Berkowitz, Avi Schwalb, Beatrice Tiosano
{"title":"The Road Less Traveled: Ciliary Sulcus Implantation of the Preserflo MicroShunt.","authors":"Meishar Meisel, Eran Berkowitz, Avi Schwalb, Beatrice Tiosano","doi":"10.1159/000543219","DOIUrl":"10.1159/000543219","url":null,"abstract":"<p><strong>Introduction: </strong>Herein, we report on the option and clinical advantage of the Preserflo MicroShunt insertion into the posterior chamber ciliary sulcus in a patient with advanced pseudoexfoliation glaucoma at a high risk of corneal decompensation.</p><p><strong>Case presentation: </strong>We describe a 64-year-old advanced pseudoexfoliation glaucoma patient who despite maximal tolerated medical therapy and two failed glaucoma surgeries, still suffered from uncontrolled intraocular pressure (IOP) of 36 mm Hg in his left eye. The patient underwent the implantation of the Preserflo MicroShunt. The shunt was placed nasally into an area of unscarred conjunctiva, with the anterior part of the shunt inserted into the ciliary sulcus. Postoperatively, the patient's IOP dropped to 6 mm Hg on the first day and stabilized at 11 mm Hg at the 6-month mark. An elevated, posteriorly located bleb was observed, and the patient no longer required additional topical medications. Endothelial cell (EC) count remained stable with no signs of corneal edema. The patient did not experience any serious postoperative complications.</p><p><strong>Conclusion: </strong>Implantation of the Preserflo MicroShunt into the ciliary sulcus appears to be a viable option for patients at high risk of corneal decompensation, hence, offering effective IOP control while minimizing EC loss. Further studies with larger patient groups are warranted to better evaluate the safety and efficacy of this technique.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"68-73"},"PeriodicalIF":0.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report. 标准剂量头孢呋辛腹腔注射致中毒性黄斑病变1例。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-01-28 eCollection Date: 2025-01-01 DOI: 10.1159/000543837
Maria E Pantelidou, Stylianos Bebis, Elias P Pantelidis, Tryfon Rotsos
{"title":"Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report.","authors":"Maria E Pantelidou, Stylianos Bebis, Elias P Pantelidis, Tryfon Rotsos","doi":"10.1159/000543837","DOIUrl":"10.1159/000543837","url":null,"abstract":"<p><strong>Introduction: </strong>Cefuroxime-induced toxic maculopathy can occur when an incorrect or correct dilution is injected intracamerally during cataract surgery.</p><p><strong>Case report: </strong>An 83-year-old male developed toxic maculopathy on the first postoperative day after uneventful cataract surgery. An investigation of the case confirmed that the patient developed sporadic toxic maculopathy after a standard intracameral cefuroxime dose. The patient showed complete recovery of vision during the first postoperative week.</p><p><strong>Conclusion: </strong>Cefuroxime-induced toxic maculopathy may occur sporadically and have a good visual outcome. It may be distinguished from toxic maculopathy induced by incorrect dilution based on its different clinical appearance and, in some cases, the guarded outcome. Correct dilution of cefuroxime is of utmost importance.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"171-181"},"PeriodicalIF":0.5,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Paraneoplastic Optic Neuropathy as the First Presentation of Preclinical Small Cell Lung Cancer: Case Report. 双侧副肿瘤视神经病变作为临床前小细胞肺癌的首次表现:病例报告。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-01-24 eCollection Date: 2025-01-01 DOI: 10.1159/000543516
Sara Sharif, Dhruv Gor, Haider Shah, Nima Ghadiri
{"title":"Bilateral Paraneoplastic Optic Neuropathy as the First Presentation of Preclinical Small Cell Lung Cancer: Case Report.","authors":"Sara Sharif, Dhruv Gor, Haider Shah, Nima Ghadiri","doi":"10.1159/000543516","DOIUrl":"10.1159/000543516","url":null,"abstract":"<p><strong>Introduction: </strong>Paraneoplastic optic neuropathy (PON) is a rare immune-mediated optic neuropathy, secondary to an underlying malignancy. This report describes a rare case of bilateral PON as the initial manifestation in a 77-year-old male, leading to the early detection and treatment of preclinical small cell lung cancer (SCLC).</p><p><strong>Case presentation: </strong>The patient initially presented with incidental bilateral disc swelling but was asymptomatic, with preserved visual function. Initial investigations, including orbito-cranial imaging, lumbar puncture, temporal artery ultrasound, and serological testing, were inconclusive. Six weeks later, the patient had persistent disc swelling with compromised bilateral visual function and was commenced on oral steroids. Further diagnostic workup identified paraneoplastic antibodies (anti-CV2/CRMP-5 and anti-Hu) and PET scan findings consistent with a nodular SCLC. Following biopsy confirmation, the patient underwent carboplatin and etoposide chemotherapy, followed by radiotherapy. Initial oral steroids, prior to cancer treatment, resulted in resolution of optic disc swelling and stabilization of visual function.</p><p><strong>Conclusion: </strong>This case underscores the importance of a systematic approach to optic neuropathies where an initial diagnosis is not found, revisiting diagnostic pathways when initial findings remain ambiguous, and consideration of PON as a differential - even in the absence of known malignancy or typical cancer symptoms. Timely recognition allows for early intervention, improving patient outcomes. This report contributes to the limited literature on PON and highlights the role of multidisciplinary care in managing complex cases involving paraneoplastic syndromes.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"163-170"},"PeriodicalIF":0.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Diathermy-Induced Corneal Burn following Upper Eyelid Blepharoplasty with Multilayer Amniotic Membrane Transplantation: A Case Report and Review of the Literature. 多层羊膜移植上睑成形术后透热性角膜烧伤的处理:1例报告及文献复习。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-01-24 eCollection Date: 2025-01-01 DOI: 10.1159/000543760
Konstantina Bachtalia, Sotiria Palioura
{"title":"Management of Diathermy-Induced Corneal Burn following Upper Eyelid Blepharoplasty with Multilayer Amniotic Membrane Transplantation: A Case Report and Review of the Literature.","authors":"Konstantina Bachtalia, Sotiria Palioura","doi":"10.1159/000543760","DOIUrl":"10.1159/000543760","url":null,"abstract":"<p><strong>Introduction: </strong>Thermal injuries associated with cosmetic eyelid surgery can significantly impair corneal integrity, potentially leading to vision loss. Conventional management, including bandage contact lens use, topical steroids, lubrication, autologous serum tears, and vitamin C, plays a crucial role in preventing long-term complications. This case report explores the potential benefits of multilayer amniotic membrane transplantation (AMT) as an adjunct to standard therapy for treating diathermy-associated corneal burns. Review of the literature advocates the beneficial effects of supplementary AMT in managing thermal corneal trauma.</p><p><strong>Case description: </strong>A 75-year-old man presented with unilateral diathermy-associated corneal laceration superior to the visual axis following cosmetic blepharoplasty. Vision had deteriorated from his baseline 20/30 to 20/125 postoperatively. Intervention involved multilayer AMT alongside standard care, including topical steroids and antibiotics, oral doxycycline, and vitamin C. Postoperative course was monitored with anterior segment optical coherence tomography (AS-OCT) imaging. By 3 months, complete corneal healing and restoration of baseline visual acuity were achieved.</p><p><strong>Conclusion: </strong>This is the first documented case of multilayer AMT as an effective supplement to conventional management of diathermy-associated corneal injury. While AMTs unique properties likely contributed to corneal healing and visual recovery, the results should be interpreted in the context of a multimodal therapeutic approach.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"133-142"},"PeriodicalIF":0.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demarcation Laser Photocoagulation for Rhegmatogenous Retinal Detachment: Outcomes in Symptomatic and Asymptomatic Patients. 划定激光光凝治疗孔源性视网膜脱离:有症状和无症状患者的结果。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI: 10.1159/000543240
Jeffrey A Brown, Louis Z Cai, Jesse D Sengillo, James Lin, Harry W Flynn
{"title":"Demarcation Laser Photocoagulation for Rhegmatogenous Retinal Detachment: Outcomes in Symptomatic and Asymptomatic Patients.","authors":"Jeffrey A Brown, Louis Z Cai, Jesse D Sengillo, James Lin, Harry W Flynn","doi":"10.1159/000543240","DOIUrl":"10.1159/000543240","url":null,"abstract":"<p><strong>Introduction: </strong>Demarcation laser photocoagulation (DLP) is an infrequently utilized modality for limited retinal detachments. The current study, a retrospective consecutive case series, reviewed anatomic and visual outcomes in these patients at a single academic center.</p><p><strong>Case presentations: </strong>A search of the electronic medical record identified 10 eyes of 10 patients. Five of the 10 patients were asymptomatic at the time of initial treatment. Five patients had symptoms corresponding to retinal detachment. The asymptomatic patients remained stable without progression at the last follow-up (range 1-8 years). In 2 of 5 symptomatic patients, the retinal detachment progressed through the laser demarcation and, subsequently, underwent vitreoretinal surgery. At the last follow-up, the retina was attached in all five symptomatic patients.</p><p><strong>Conclusion: </strong>In this small series of patients undergoing DLP, the retina remained stable in asymptomatic patients but the retinal detachment progressed through the laser demarcation in the majority of symptomatic patients.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"114-123"},"PeriodicalIF":0.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nodular Scleritis as Isolated Symptom of IgG4-Related Disease, Mimicking as Conjunctival Lymphoma: A Case Report. 结节性巩膜炎作为igg4相关疾病的孤立症状,模拟结膜淋巴瘤1例报告
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1159/000543084
Noémie Delaissé, Daniel Blockmans, Rita Van Ginderdeuren, Guy Missotten
{"title":"Nodular Scleritis as Isolated Symptom of IgG4-Related Disease, Mimicking as Conjunctival Lymphoma: A Case Report.","authors":"Noémie Delaissé, Daniel Blockmans, Rita Van Ginderdeuren, Guy Missotten","doi":"10.1159/000543084","DOIUrl":"10.1159/000543084","url":null,"abstract":"<p><strong>Introduction: </strong>Immunoglobulin G4-related disease (IgG4-RD) is a systemic, immune-mediated disorder marked by the infiltration of IgG4-positive plasma cells and fibrosis in affected organs. This report presents a rare case of a patient with isolated nodular scleritis as an IgG4-RD (in a more precise way antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis [AAV] and IgG4-RD overlap syndrome).</p><p><strong>Case presentation: </strong>A 51-year-old woman was referred with the presumed diagnosis of conjunctival lymphoma due to a painful, salmon-colored lesion in the superior conjunctiva of the right eye. A biopsy of the conjunctiva showed a lymphoplasmacytic infiltrate with multiple IgG4-positive cells (>200 cells/high power field), elevated IgG4/IgG ratio of 66% and fibrotic tissue without obvious vasculitis, confirming the diagnosis of IgG4-related disease (IgG4-RD). ANCAs directly against myeloperoxidase were also positive, suggesting AAV. Given that the clinical signs align with both disease entities, it was concluded that the case fits in its restricted sense the newly described overlap syndrome. The scleritis was successfully treated with a tapering dose of corticosteroids and rituximab.</p><p><strong>Conclusion: </strong>This case illustrates a rare presentation of scleritis as an IgG4-RD (in a more precise way AAV and IgG4-RD overlap syndrome) and demonstrates that rituximab and low dose of corticosteroids can lead to remission.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"102-106"},"PeriodicalIF":0.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Macular Atrophy after Macular Hole Surgery in an Eye with Retinitis Pigmentosa. 色素性视网膜炎的黄斑孔手术后黄斑萎缩的发展。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1159/000543599
Yuki Goto, Kazuki Kuniyoshi, Kensuke Goto, Tomoyasu Kayazawa, Taro Kominami, Fukutaro Mano, Masuo Sakamoto, Chiharu Iwahashi, Shunji Kusaka
{"title":"Development of Macular Atrophy after Macular Hole Surgery in an Eye with Retinitis Pigmentosa.","authors":"Yuki Goto, Kazuki Kuniyoshi, Kensuke Goto, Tomoyasu Kayazawa, Taro Kominami, Fukutaro Mano, Masuo Sakamoto, Chiharu Iwahashi, Shunji Kusaka","doi":"10.1159/000543599","DOIUrl":"10.1159/000543599","url":null,"abstract":"<p><strong>Introduction: </strong>Macular hole is a rare complication in patients with retinitis pigmentosa that significantly reduces visual acuity. Although vitreous surgery for macular holes generally yields favorable outcomes, postoperative macular atrophy has been reported. We report the second case of retinitis pigmentosa in a patient who developed a 13-year progressive macular atrophy after macular hole surgery.</p><p><strong>Case presentation: </strong>A 64-year-old Japanese woman, who had been diagnosed with retinitis pigmentosa at 52 years of age, presented to our hospital with blurred vision in her left eye. Phacovitrectomy of the left eye was performed after a full-thickness macular hole was revealed by optical coherence tomography. We stained the internal limiting membrane during surgery using 0.05% indocyanine green and peeled it around the macular hole. Nevertheless, slight atrophy of the retinal pigment epithelium appeared in the left macula 17 days after surgery. The macular hole closed 1 year after surgery, and the macular atrophy gradually became more apparent and enlarged. Thirteen years later, atrophy had expanded to 2.5-disc diameters, and the left decimal best-corrected visual acuity was 0.1; no macular degeneration appeared in the right eye. Genetic examination revealed compound heterozygous variants in the <i>EYS</i> gene.</p><p><strong>Conclusion: </strong>Macular atrophy can develop after dye-assisted macular hole surgery for patients with retinitis pigmentosa. Potential risk factors for the development of postoperative macular atrophy include dye toxicity, light toxicity, surgical intervention in the macula, postoperative inflammation, and genotype. However, the exact cause of atrophy remains uncertain.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"107-113"},"PeriodicalIF":0.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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