Maria E Pantelidou, Stylianos Bebis, Elias P Pantelidis, Tryfon Rotsos
{"title":"标准剂量头孢呋辛腹腔注射致中毒性黄斑病变1例。","authors":"Maria E Pantelidou, Stylianos Bebis, Elias P Pantelidis, Tryfon Rotsos","doi":"10.1159/000543837","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Cefuroxime-induced toxic maculopathy can occur when an incorrect or correct dilution is injected intracamerally during cataract surgery.</p><p><strong>Case report: </strong>An 83-year-old male developed toxic maculopathy on the first postoperative day after uneventful cataract surgery. An investigation of the case confirmed that the patient developed sporadic toxic maculopathy after a standard intracameral cefuroxime dose. The patient showed complete recovery of vision during the first postoperative week.</p><p><strong>Conclusion: </strong>Cefuroxime-induced toxic maculopathy may occur sporadically and have a good visual outcome. It may be distinguished from toxic maculopathy induced by incorrect dilution based on its different clinical appearance and, in some cases, the guarded outcome. Correct dilution of cefuroxime is of utmost importance.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"16 1","pages":"171-181"},"PeriodicalIF":0.6000,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245152/pdf/","citationCount":"0","resultStr":"{\"title\":\"Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report.\",\"authors\":\"Maria E Pantelidou, Stylianos Bebis, Elias P Pantelidis, Tryfon Rotsos\",\"doi\":\"10.1159/000543837\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Cefuroxime-induced toxic maculopathy can occur when an incorrect or correct dilution is injected intracamerally during cataract surgery.</p><p><strong>Case report: </strong>An 83-year-old male developed toxic maculopathy on the first postoperative day after uneventful cataract surgery. An investigation of the case confirmed that the patient developed sporadic toxic maculopathy after a standard intracameral cefuroxime dose. The patient showed complete recovery of vision during the first postoperative week.</p><p><strong>Conclusion: </strong>Cefuroxime-induced toxic maculopathy may occur sporadically and have a good visual outcome. It may be distinguished from toxic maculopathy induced by incorrect dilution based on its different clinical appearance and, in some cases, the guarded outcome. Correct dilution of cefuroxime is of utmost importance.</p>\",\"PeriodicalId\":9635,\"journal\":{\"name\":\"Case Reports in Ophthalmology\",\"volume\":\"16 1\",\"pages\":\"171-181\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-01-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245152/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000543837\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000543837","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report.
Introduction: Cefuroxime-induced toxic maculopathy can occur when an incorrect or correct dilution is injected intracamerally during cataract surgery.
Case report: An 83-year-old male developed toxic maculopathy on the first postoperative day after uneventful cataract surgery. An investigation of the case confirmed that the patient developed sporadic toxic maculopathy after a standard intracameral cefuroxime dose. The patient showed complete recovery of vision during the first postoperative week.
Conclusion: Cefuroxime-induced toxic maculopathy may occur sporadically and have a good visual outcome. It may be distinguished from toxic maculopathy induced by incorrect dilution based on its different clinical appearance and, in some cases, the guarded outcome. Correct dilution of cefuroxime is of utmost importance.
期刊介绍：
This peer-reviewed online-only journal publishes original case reports covering the entire spectrum of ophthalmology, including prevention, diagnosis, treatment, toxicities of therapy, supportive care, quality-of-life, and survivorship issues. The submission of negative results is strongly encouraged. The journal will also accept case reports dealing with the use of novel technologies, both in the arena of diagnosis and treatment. Supplementary material is welcomed. The intent of the journal is to provide clinicians and researchers with a tool to disseminate their personal experiences to a wider public as well as to review interesting cases encountered by colleagues all over the world. Universally used terms can be searched across the entire growing collection of case reports, further facilitating the retrieval of specific information. Following the open access principle, the entire contents can be retrieved at no charge, guaranteeing easy access to this valuable source of anecdotal information at all times.
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