Kim Madundo, Godwin Nnko, Leila Mwakipunda, Glory Makupa, Furaha Serventi
{"title":"Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report.","authors":"Kim Madundo, Godwin Nnko, Leila Mwakipunda, Glory Makupa, Furaha Serventi","doi":"10.1093/omcr/omae206","DOIUrl":"10.1093/omcr/omae206","url":null,"abstract":"<p><p>Motor and vocal tics typically manifest during childhood. Less often, tics can occur due to the use of substances or medications which raise dopamine levels. This case report describes an unusual occurrence of tics in an elderly man undergoing androgen deprivation with Goserelin for prostate cancer. Comprehensive assessments ruled out infectious, metabolic, psychiatric, and neurological conditions. The tics resolved with low-dose Risperidone, without adverse effects. This case underscores the potential for medication-induced tics in older adults, highlighting the need for increased awareness among healthcare providers regarding the neuropsychiatric effects of cancer therapies. Future research should further investigate these phenomena and their implications for treatment strategies.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae206"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyle Yuan, Melissa M Van Dellen, Joshua L Fenderson
{"title":"Double the trouble: pulmonary enteric adenocarcinoma with synchronous contralateral pulmonary adenocarcinoma.","authors":"Kyle Yuan, Melissa M Van Dellen, Joshua L Fenderson","doi":"10.1093/omcr/omae195","DOIUrl":"10.1093/omcr/omae195","url":null,"abstract":"<p><p>Pulmonary enteric adenocarcinoma (PEAC) is a rare subtype of non-small cell lung cancer with morphological and immunohistochemical features that are nearly indistinguishable from those of metastatic colorectal carcinoma. Owing to these overlapping features, diagnosis and treatment of PEAC can present a clinical challenge. We report the case of a 78-year-old man with synchronously diagnosed locally advanced pulmonary adenocarcinoma of the left lower lobe and localized right lower lobe PEAC. These malignancies exhibited distinct tumor molecular profiles and differed in their kinetic response to chemoimmunotherapy. We describe plausible mechanisms by which two distinct pulmonary malignancies are present in the contralateral lobes. To the best of our knowledge, this is the first reported case of synchronous invasive pulmonary adenocarcinoma and PEAC.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae195"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scout In, Scout out: Savi scout reflector traversing a dilated duct to the nipple in breast cancer localisation-a case report.","authors":"Aman Saswat Sahoo, Monther Salman, Bhuvi Singh, Gina Weston-Petrides, Lilia Ragad, Rasheed Elayyan","doi":"10.1093/omcr/omae196","DOIUrl":"10.1093/omcr/omae196","url":null,"abstract":"<p><strong>Introduction: </strong>Savi scout system is being widely used for localising and excising breast tumours. While the migration of scout reflectors has been documented, this is the first case of a Savi Scout reflector migrating through a dilated duct near the lesion and coming out of the nipple.</p><p><strong>Case presentation: </strong>A 56-year-old postmenopausal woman with a history of right breast intraductal papilloma which transformed to Grade II Invasive Ductal Carcinoma (IDC) has a Savi Scout reflector placed in the tumour. However, it migrated through a dilated duct and emerged at the nipple, causing severe pain. The reflector was then surgically removed, and the patient subsequently underwent wide local excision with skin marker localisation.</p><p><strong>Conclusion: </strong>Anatomical variations such as presence of dilated ducts need to be considered before placing scout reflectors. Appropriate positioning would prevent them from migrating through such ducts avoiding patient discomfort and further procedures for localisation.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae196"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Saenz, Juan P Cóbar, Victor H Argueta, Ricardo A Caravantes
{"title":"Unexpected diagnosis: a case of incidental congenital diaphragmatic hernia.","authors":"Daniela Saenz, Juan P Cóbar, Victor H Argueta, Ricardo A Caravantes","doi":"10.1093/omcr/omae193","DOIUrl":"10.1093/omcr/omae193","url":null,"abstract":"<p><p>Congenital diaphragmatic hernias (CHD) are rare anomalies resulting from the failure of the diaphragm to form. Bochdalek hernias are characterized by posterolateral displacement of abdominal organs into the chest. The condition's clinical presentation is variable and commonly presents with acute respiratory distress after birth. Timely recognition and management are crucial due to the associated morbidity and mortality rates. In the present case, a diaphragmatic hernia was discovered incidentally in a 1-year-old patient following an appendectomy. This case highlights the diverse clinical presentations and diagnostic challenges of Bochdalek hernias, reinforcing the importance of interdisciplinary collaboration for effective patient care.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae193"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erysipeloid cutaneous Leishmaniasis treated with the combination of metronidazole and clarithromycin.","authors":"Meryem Khallouki, Khaoula Jaatar, Layla Bendaoud, Mariem Aboudourib, Said Amal, Ouafa Hocar","doi":"10.1093/omcr/omae194","DOIUrl":"10.1093/omcr/omae194","url":null,"abstract":"<p><p>Leishmaniasis is caused by an intracellular parasite transmitted to humans by the bite of a sandfly: Phlebotomus. The disease can present in three ways: visceral, cutaneous, or mucocutaneous forms. Unusual clinical presentations of cutaneous leishmaniasis have been reported: psoriasiform, eczematiform, erysipeloid, and sporotrichoid, depending on host immune status and Leishmania subspecies. We report a case of an unusual presentation of erysipeloid cutaneous leishmaniasis treated with the combination of Metronidazole and Clarithromycin. A 67-year-old woman presented with a 2-month history of swelling of the centrofacial region, with an erythematous and edematous plaque; the episode was treated as facial erysipelas with antibiotics. In the absence of improvement, the diagnosis of cutaneous leishmaniasis in its erysipeloid form was suspected and then confirmed by a skin smear showing the presence of leishmania amastigotes. The patient was treated with metronidazole and clarithromycin for 30 days, with good progression.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae194"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Hafiz Kamarul Bahrin, Hidayatul Nabila Rosaidi, Ammar Mohd Amin, Mirza Faisal Anwar Baig, Martyn Dibb
{"title":"Spontaneous Jejunal perforation in coeliac disease: diagnostic dilemma and navigating treatment beyond gluten-free diet in the absence of refractory disease.","authors":"Muhammad Hafiz Kamarul Bahrin, Hidayatul Nabila Rosaidi, Ammar Mohd Amin, Mirza Faisal Anwar Baig, Martyn Dibb","doi":"10.1093/omcr/omae210","DOIUrl":"10.1093/omcr/omae210","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae210"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deciphering the challenge: rhabdomyolysis diagnosis in food-dependent exercise-induced anaphylaxis.","authors":"Tianci Tang, Jiahua Zhang, Jieqiong Wu, Ye Zhang","doi":"10.1093/omcr/omae200","DOIUrl":"10.1093/omcr/omae200","url":null,"abstract":"<p><p>Food-dependent exercise-induced allergies are a specific type of food allergy. However, in some cases, allergies may appear along with other diseases. Patients with allergies and concomitant rhabdomyolysis have rarely been reported. Herein, we report a 30-year-old male patient with rhabdomyolysis and no prior history of food-dependent exercise-induced allergy, and discuss our management approach. The aim of this report is to provide new insights into the diagnosis of this condition and assist clinicians in its identification.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae200"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana Elizabeth Vázquez-Hernández, Ana Lilia Peralta-Amaro, Carlos Antonio Villegas-Chávez, Luis Rodrigo Bañuelos-García, Jaime Enrique Hernández-Utrera, Leslie Moranchel-García, Abihai Lucas-Hernández
{"title":"Hypocomplementemic glomerulonephritis associated with chronic infective endocarditis in a young patient with undiagnosed congenital heart disease.","authors":"Adriana Elizabeth Vázquez-Hernández, Ana Lilia Peralta-Amaro, Carlos Antonio Villegas-Chávez, Luis Rodrigo Bañuelos-García, Jaime Enrique Hernández-Utrera, Leslie Moranchel-García, Abihai Lucas-Hernández","doi":"10.1093/omcr/omae204","DOIUrl":"10.1093/omcr/omae204","url":null,"abstract":"<p><p>Infective endocarditis is a potentially fatal condition, especially when kidney damage occurs. Acute kidney injury may occur in 2 out of 3 patients with infective endocarditis, which must be adequately identified for optimal treatment.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae204"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramsha Ansari, Deepanjali Golshetty, Vishrutha Poojari, Shivangi Tetarbe, Ira Shah
{"title":"Arthritis with chronic pancreatitis-do not forget pancreatitis, panniculitis and polyarthritis (PPP) syndrome.","authors":"Ramsha Ansari, Deepanjali Golshetty, Vishrutha Poojari, Shivangi Tetarbe, Ira Shah","doi":"10.1093/omcr/omae203","DOIUrl":"10.1093/omcr/omae203","url":null,"abstract":"<p><p>Pancreatitis panniculitis and polyarthritis syndrome (PPP) syndrome is a rare complication of existing pancreatic disorders which include a triad of pancreatitis, oligo or monoarthritis and lobular panniculitis. We describe a case of a 3-year-old female child who presented with chronic pancreatitis and later developed knee pain during hospitalization. Other causes of arthritis were ruled out and pancreatitis-related arthritis, PPP syndrome was suspected. PPP syndrome treatment primarily involves managing the underlying pancreatic cause. In our case, managing the chronic pancreatitis with NSAIDs significantly improved the joint involvement.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae203"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omran Khaled Janoud, Raya Ehsan Alok, Khozama Ali Amer, Rana Mohammad Awwad, Wessam Souliman, Ghuroub Alkhayer
{"title":"Challenging diagnosis: unusual presentation of Unicentric Castleman disease-a case report.","authors":"Omran Khaled Janoud, Raya Ehsan Alok, Khozama Ali Amer, Rana Mohammad Awwad, Wessam Souliman, Ghuroub Alkhayer","doi":"10.1093/omcr/omae181","DOIUrl":"10.1093/omcr/omae181","url":null,"abstract":"<p><p>Castleman's Disease is an idiopathic rare lymphoproliferative disorder that is clinically Classified to multicentric to unicentric types. Only few cases were reported in children, with majority of them are unicentric and usually located in the mediastinum. We report a unique case of a 13-year-old boy who presented with a palpable enlarged mass in the left inguinal region without any constitutional symptoms. Surgical removal of this mass was essential to exclude worrying causes. Pathologic examination revealed proliferative changes consistent with Castleman's disease plasma cell type which is one of the rarest forms of the disease in children. To our knowledge, this case is the first reported case of Unicentric Castleman Disease (UCD) in the inguinal area. During a 12-month-period of follow-up, no additional lymph node enlargements or other symptoms were reported. In conclusion, any isolated lymph node enlargement wherever it is, especially in a child, should impose UCD as a possible differential diagnosis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae181"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}