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Microangiopathic Hemolytic Anemia as paraneoplastic syndrome secondary to Pheochromocytoma: a rare case report. 嗜铬细胞瘤继发于微血管病性溶血性贫血：罕见病例报告。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omaf034
Omar Q Heih, Mahmoud R Manasra, Ziad F Salah, Monther M Hroub, Hassan Arafat, Bashir I Abu Aqeel, Ahmad G Hammouri
{"title":"Microangiopathic Hemolytic Anemia as paraneoplastic syndrome secondary to Pheochromocytoma: a rare case report.","authors":"Omar Q Heih, Mahmoud R Manasra, Ziad F Salah, Monther M Hroub, Hassan Arafat, Bashir I Abu Aqeel, Ahmad G Hammouri","doi":"10.1093/omcr/omaf034","DOIUrl":"10.1093/omcr/omaf034","url":null,"abstract":"<p><p>Pheochromocytoma is a rare adrenal tumor that secretes catecholamines. Microangiopathic hemolytic anemia, a kind of hemolytic anemia in which erythrocytes are destroyed in microscopic blood capillaries, resulting in fragmentation and hemolysis. This condition is an uncommon but significant consequence observed most commonly in malignant pheochromocytoma. In this case report, we present a 21-year-old single female with a strong family history of endocrine malignancy. She was referred to our hospital for chemotherapy due to a diagnosis of malignant pheochromocytoma, which had metastasized to the urinary bladder, bone, and lung. Additionally, she developed microangiopathic hemolytic anemia as a paraneoplastic syndrome.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omaf034"},"PeriodicalIF":0.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case report of severe organophosphate poisoning and aspiration pneumonitis treated with exchange blood transfusion. 换血治疗重度有机磷中毒吸入性肺炎1例。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omaf031
Adaugo C Owobu, Chiemeka J Ogbonnaya, Jeremiah Alli, Abimbola A Ekusunmi
{"title":"A case report of severe organophosphate poisoning and aspiration pneumonitis treated with exchange blood transfusion.","authors":"Adaugo C Owobu, Chiemeka J Ogbonnaya, Jeremiah Alli, Abimbola A Ekusunmi","doi":"10.1093/omcr/omaf031","DOIUrl":"10.1093/omcr/omaf031","url":null,"abstract":"<p><p>Background Organophosphate poisoning causes a significant disease burden in low- and middle-income countries and places a huge demand on critical care facilities. Case report We present the case of a 5-year-old with severe organophosphate poisoning from ingestion of chlorpyrifos, further worsened by aspiration of a charcoal-palm oil mixture. The clinical illness was marked by respiratory failure, shock, coma and type I paralysis. The patient was treated in the emergency department with noninvasive ventilation, multiple episodes of exchange transfusion, intravenous atropine, inotrope infusion, antibiotics and steroids. The patient responded rapidly to treatment, did not develop intermediate syndrome and was discharged after 10 days of admission. Conclusion The dearth of paediatric intensive care facilities and complex medical equipment in many low- and middle-income countries necessitates the use of other treatment modalities for critical conditions. This case report highlights the relevance of exchange transfusion in detoxification of severe organophosphate poisoning in children.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omaf031"},"PeriodicalIF":0.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatic steatosis in complicated kwashiorkor-an ultrasound case report. 肝脂肪变性合并合并血液病超声1例报告。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omaf033
Zachary Linneman, Innocent Wacha, Kelly Dietz, Esther Babirekere-Iriso, Nicolette Nabukeera-Barungi, Ezekiel Mupere
{"title":"Hepatic steatosis in complicated kwashiorkor-an ultrasound case report.","authors":"Zachary Linneman, Innocent Wacha, Kelly Dietz, Esther Babirekere-Iriso, Nicolette Nabukeera-Barungi, Ezekiel Mupere","doi":"10.1093/omcr/omaf033","DOIUrl":"10.1093/omcr/omaf033","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omaf033"},"PeriodicalIF":0.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PD-1/PD-L1 checkpoint inhibitor-induced encephalitis in patients with lung adenocarcinoma: a report of three cases. 肺腺癌患者PD-1/PD-L1检查点抑制剂诱导脑炎：附3例报告
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omae201
Takayo Ota, Masaaki Terashima, Yukihiro Hamada, Shuichi Ueno, Shigeru Kawai, Noriko Tanaka, Kaoru Matsui, Noriyuki Masuda
{"title":"PD-1/PD-L1 checkpoint inhibitor-induced encephalitis in patients with lung adenocarcinoma: a report of three cases.","authors":"Takayo Ota, Masaaki Terashima, Yukihiro Hamada, Shuichi Ueno, Shigeru Kawai, Noriko Tanaka, Kaoru Matsui, Noriyuki Masuda","doi":"10.1093/omcr/omae201","DOIUrl":"10.1093/omcr/omae201","url":null,"abstract":"<p><p>Immune checkpoint inhibitor (ICI)-induced encephalitis is rare. We present three cases of encephalitis associated with ICIs in lung adenocarcinoma patients. These patients presented with a variety of symptoms, but one of the common symptoms for all patients was loss of consciousness. All patients responded well to steroid treatment and survived longer than one month after the onset of symptoms. These cases highlight the difficulties in diagnosing encephalitis based only on clinical information, and timely management is important to improve survival. Opportunistic infections also have to be ruled out to diagnose ICI-induced encephalitis especially when brain metastases co-exist.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae201"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-functioning pancreatic neuroendocrine tumor presenting with acute pancreatitis: a case report. 以急性胰腺炎为表现的无功能胰腺神经内分泌肿瘤1例。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omae207
Aref Al-Rajabi, Amal A Thweib, Natalia M Daghlis, Howaida A Rabba, Nameer AbuMunshar, Abdel Majeed Al Ali, Izzeddin A Bakri
{"title":"Non-functioning pancreatic neuroendocrine tumor presenting with acute pancreatitis: a case report.","authors":"Aref Al-Rajabi, Amal A Thweib, Natalia M Daghlis, Howaida A Rabba, Nameer AbuMunshar, Abdel Majeed Al Ali, Izzeddin A Bakri","doi":"10.1093/omcr/omae207","DOIUrl":"https://doi.org/10.1093/omcr/omae207","url":null,"abstract":"<p><p>Pancreatic neuroendocrine tumors (pNETs) are a group of tumors with complex therapeutic options that differ according to pathological grading, clinical staging, and the existence of hormone secretion symptoms. We report a 34-year-old male with recurrent acute pancreatitis due to a non-functioning pNET. He presented with intermittent epigastric pain and elevated pancreatic enzymes. MRCP and endoscopic ultrasound revealed an oval lesion near the pancreatic head, confirmed as a grade 1 neuroendocrine tumor on biopsy. A Whipple procedure was performed based on tumor size and location. This case highlights the rare occurrence of pNET presenting with acute pancreatitis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae207"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pheochromocytoma presenting with chest pain, heart failure and elevated pancreatic enzymes. 嗜铬细胞瘤表现为胸痛，心力衰竭和胰酶升高。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omae202
Qinglang Li, Shiyao Cheng, Zhichong Chen, Xi Hong, Biyao Wang, Mao Ouyang
{"title":"Pheochromocytoma presenting with chest pain, heart failure and elevated pancreatic enzymes.","authors":"Qinglang Li, Shiyao Cheng, Zhichong Chen, Xi Hong, Biyao Wang, Mao Ouyang","doi":"10.1093/omcr/omae202","DOIUrl":"10.1093/omcr/omae202","url":null,"abstract":"<p><p>Pheochromocytoma can present with various clinical manifestations and potentially mislead physicians by mimicking other conditions. Here we report a patient presenting with acute chest pain, de Winter electrocardiogram (ECG) changes, and elevated troponin I; the patient was initially diagnosed with acute myocardial infarction, but coronary angiography revealed no significant stenosis. He experienced heart failure symptoms with elevated serum amylase, lipase, and catecholamines. Further examination confirmed the diagnosis of pheochromocytoma, the patient later underwent tumor resection and recovered well. This case highlights the importance of rapid recognition and management of pheochromocytoma.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae202"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catastrophic antiphospholipid syndrome presenting with a stroke as a first presentation: case report. 灾难性抗磷脂综合征以卒中为首发表现：病例报告。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omae208
Ahmad Nouri, Ameer Awashra, Mohammad Alnees, Hadi Rabee, Alaa Shamlawi
{"title":"Catastrophic antiphospholipid syndrome presenting with a stroke as a first presentation: case report.","authors":"Ahmad Nouri, Ameer Awashra, Mohammad Alnees, Hadi Rabee, Alaa Shamlawi","doi":"10.1093/omcr/omae208","DOIUrl":"10.1093/omcr/omae208","url":null,"abstract":"<p><p>Catastrophic Antiphospholipid Syndrome (CAPS), an autoimmune disease that causes multi-organ thromboses leading to their failure, is a rapidly developing form of antiphospholipid syndrome (APS). APS may be a primary disease or secondary to an autoimmune condition like Systemic Lupus Erythematosus (SLE). A 31-year-old male patient with unremarkable medical history presented with a sudden onset of left-sided body weakness including upper and lower extremities, frontal headache, and slurred speech. Diagnostic workup revealed diffuse ST elevation with elevated cardiac enzymes, elevated inflammatory markers, prolonged activated partial thromboplastin time (aPTT), hemolytic anemia, and intrarenal kidney injury. Further investigations confirmed the diagnosis of probable CAPS secondary to SLE, based on the simultaneous involvement of the brain, heart, and kidneys, along with the presence of positive antiphospholipid antibodies (aPL). The patient showed significant improvement in neurological functioning after treatment with Methylprednisolone, Hydroxychloroquine, Colchicine, and Rituximab.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae208"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report: unilateral absence of the left pulmonary artery with left gastric artery collateral supply and hematologic disorder. 病例报告：单侧左肺动脉缺失伴胃左动脉侧支供应伴血液学紊乱。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omae209
Naomie Condé, Mathew Carias, Josephine Pressacco
{"title":"Case report: unilateral absence of the left pulmonary artery with left gastric artery collateral supply and hematologic disorder.","authors":"Naomie Condé, Mathew Carias, Josephine Pressacco","doi":"10.1093/omcr/omae209","DOIUrl":"10.1093/omcr/omae209","url":null,"abstract":"<p><p>Unilateral absence of the pulmonary artery is a congenital disorder resulting from malformation of the sixth aortic arch during embryogenesis. This case report presents a unique instance of unilateral absence of the pulmonary artery, incidentally discovered in an individual with multiple myeloma. Despite a history of recurrent childhood pulmonary infections, the patient remained asymptomatic until presenting with symptoms of myeloma. Imaging revealed a right-sided aortic arch, absent left pulmonary artery, and left lung atrophy with atelectasis. Among various collateral arteries, a notable finding in this case is the left gastric artery supplying the left lower lobe.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae209"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and ECMO treatment of a critically ill patient with heart attack: a case report. 危重心脏病患者的诊断与ECMO治疗1例。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omae205
Xuan Zhang, Yiping Deng, Xinlong Liu
{"title":"Diagnosis and ECMO treatment of a critically ill patient with heart attack: a case report.","authors":"Xuan Zhang, Yiping Deng, Xinlong Liu","doi":"10.1093/omcr/omae205","DOIUrl":"10.1093/omcr/omae205","url":null,"abstract":"<p><p>We report a case of a 49-year-old male diagnosed with acute myocardial infarction (AMI). After continuous cardiopulmonary resuscitation (CPR), percutaneous coronary intervention (PCI), and treatment with continuous renal replacement therapy (CRRT), extracorporeal membrane oxygenation (ECMO) and mechanical ventilation, the patient's condition improved well without sequela. This case report will demonstrate how ECMO and intensive care was used to acute myocardial infarction and cardiogenic shock.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae205"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The second generation metagenomic sequencing of cerebrospinal fluid for diagnosis of non-eschar scrub typhus. 第二代脑脊液宏基因组测序诊断非焦痂恙虫病。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/omcr/omae198
Shujing Li, Sufang Zhang, Tao Zhou, Zhe Ge, Yi Li, JiYing Zhang, Yifei Zhu, Shaoying Li
{"title":"The second generation metagenomic sequencing of cerebrospinal fluid for diagnosis of non-eschar scrub typhus.","authors":"Shujing Li, Sufang Zhang, Tao Zhou, Zhe Ge, Yi Li, JiYing Zhang, Yifei Zhu, Shaoying Li","doi":"10.1093/omcr/omae198","DOIUrl":"10.1093/omcr/omae198","url":null,"abstract":"<p><p>Tsutsugamushi disease, is an infectious disease transmitted by ticks and caused by the rickettsiella. It is characterized by eschar, fever, rash, and flu-like symptoms. However, diagnosing atypical cases without an eschar and with negative Weil-Felix test results poses a significant diagnostic challenge. This study presents a noteworthy case of non-eschar typhus which was effectively diagnosed using advanced next-generation sequencing (mNGS) of cerebrospinal fluid (CSF) samples.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae198"},"PeriodicalIF":0.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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