Oxford Medical Case Reports最新文献_第7页

Delayed recognition of hypomagnesemia causing refractory Hypocalcemia after Reoperative neck surgery in a resource-limited setting. a case report. 在资源有限的情况下，再手术后低镁血症导致难治性低钙血症的延迟识别。一份病例报告。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag132

Carlos Solórzano Flores, Sindy Michelle Vásquez, Andrea Pineda, Madison Rekken, Alejandra Laínez

{"title":"Delayed recognition of hypomagnesemia causing refractory Hypocalcemia after Reoperative neck surgery in a resource-limited setting. a case report.","authors":"Carlos Solórzano Flores, Sindy Michelle Vásquez, Andrea Pineda, Madison Rekken, Alejandra Laínez","doi":"10.1093/omcr/omag132","DOIUrl":"10.1093/omcr/omag132","url":null,"abstract":"Postoperative hypocalcemia following cervical surgery is typically attributed to hypoparathyroidism. However, hypomagnesemia is a reversible cause that impairs parathyroid hormone (PTH) secretion and target-organ responsiveness. We report a 35-year-old woman with recurrent symptomatic hypocalcemia after reoperative neck exploration for recurrent papillary thyroid carcinoma. Despite aggressive calcium and vitamin D supplementation, hypocalcemia persisted with inappropriately suppressed PTH. Due to resource limitations, serum magnesium evaluation was delayed until postoperative day 6, revealing severe hypomagnesemia. Magnesium repletion led to prompt serum calcium improvement and partial PTH recovery. Although the lack of contemporaneous phosphate and serial PTH measurements is a limitation, the rapid clinical response strongly supports a functional hypoparathyroid state. This case emphasizes early magnesium assessment in refractory postoperative hypocalcemia, demonstrating how resource limitations can delay diagnosis and prolong morbidity.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag132"},"PeriodicalIF":0.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An unusually small pituitary microadenoma causing severe Cushing disease in a male patient: lessons from early Radiosurgical management. 男性患者异常小的垂体微腺瘤引起严重的库欣病：早期放射外科治疗的经验教训。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag134

Bayar A Qasim, Halder J Abozait, Rende S A Kochary, Luay E Alsaoor, Saleem K Musalah

{"title":"An unusually small pituitary microadenoma causing severe Cushing disease in a male patient: lessons from early Radiosurgical management.","authors":"Bayar A Qasim, Halder J Abozait, Rende S A Kochary, Luay E Alsaoor, Saleem K Musalah","doi":"10.1093/omcr/omag134","DOIUrl":"10.1093/omcr/omag134","url":null,"abstract":"Cushing disease is a rare endocrine disorder caused by an ACTH-secreting pituitary adenoma. We report a 27-year-old male with severe hypercortisolism due to a 1.2-mm pituitary microadenoma. He presented with facial plethora, centripetal obesity, violaceous striae, hypertension, diabetes, dyslipidemia, and fatigue. Biochemical testing confirmed ACTH-dependent hypercortisolism, and 3 T MRI identified the lesion. Owing to its minute size and the anticipated difficulty of surgical localization, transsphenoidal surgery was deferred and Gamma Knife radiosurgery (GKRS) was performed as first-line therapy. After 5 months, biochemical hypercortisolism persisted, with elevated cortisol and ACTH levels. Ketoconazole 200 mg daily was subsequently initiated, resulting in normalization of serum cortisol within four weeks, ACTH levels remained elevated. Mild transient ALT elevation was observed during treatment. This case highlights that very small adenomas can cause severe disease and underscores the delayed response to GKRS, necessitating early adjunctive medical therapy to control hypercortisolism and reduce morbidity.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag134"},"PeriodicalIF":0.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Refractory urticarial dermatitis successfully treated with mycophenolate mofetil. 霉酚酸酯成功治疗难治性荨麻疹皮炎。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag140

Hugo J Leme, Marcelo Pacheco Silva, Adelina Costin, Ana Isabel Gouveia, João Alves

引用次数: 0

Case report of invasive lobular carcinoma with pineal metastasis. 侵袭性小叶癌伴松果体转移1例。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag136

Masayuki Saito, Kanna Ozaki, Hirona Banno, Mirai Ido, Manami Goto, Takahito Ando, Yukako Mouri, Junko Kousaka, Kimihito Fujii, Tsuneo Imai, Shogo Nakano

引用次数: 0

Autoimmune myelofibrosis secondary to systemic lupus erythematosus: a diagnostic challenge in a resource-limited setting. 继发于系统性红斑狼疮的自身免疫性骨髓纤维化：在资源有限的情况下的诊断挑战。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag139

Abbas Godian, Noorein Omar, Zainab Malingumu, Basil Tumaini, Elizabeth Msangi

{"title":"Autoimmune myelofibrosis secondary to systemic lupus erythematosus: a diagnostic challenge in a resource-limited setting.","authors":"Abbas Godian, Noorein Omar, Zainab Malingumu, Basil Tumaini, Elizabeth Msangi","doi":"10.1093/omcr/omag139","DOIUrl":"10.1093/omcr/omag139","url":null,"abstract":"Autoimmune myelofibrosis (AIMF) is a rare, potentially reversible cause of bone marrow failure often linked to systemic autoimmune disease. We report a diagnostically challenging case of a 26-year-old woman from sub-Saharan Africa who presented with transfusion-dependent pancytopenia and an initial dry-tap marrow, with further testing limited by financial constraints. Seven months later, evolving clinical and immunologic features-including fever, leukopenia, thrombocytopenia, malar rash, positive ANA, and a sterile exudative pleural effusion-fulfilled the 2019 EULAR/ACR criteria for systemic lupus erythematosus (SLE). AIMF secondary to SLE was subsequently diagnosed, and she demonstrated a rapid hematologic response to glucocorticoids and hydroxychloroquine, remaining transfusion-independent for over five months. This case underscores the diagnostic complexity of AIMF in resource-limited settings and highlights the importance of sustained clinical suspicion and adaptable diagnostic strategies when evaluating unexplained pancytopenia.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag139"},"PeriodicalIF":0.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subtle radiographic findings of pneumomediastinum triggered by singing. 由歌唱引起的纵隔气肿的细微影像学表现。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag135

Tatsuhiro Amano, Atsuo Maeda, Hikaru Kawakita, Tomoko Yashima, Go Haraguchi, Masahito Uchino

引用次数: 0

Charging failure due to pulse generator rotation after deep brain stimulation: a case report. 脑深部刺激后脉冲发生器旋转导致充电失败1例报告。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag137

Di Lu, Mingming Zhao, Feng Yin

引用次数: 0

Pediatric pycnodysostosis complicated by severe obstructive sleep apnea: a case report. 小儿咽脓障碍合并严重阻塞性睡眠呼吸暂停1例。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-27 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag141

Islam Tarik, Farah Makhloufi, Chafiq Mahraoui, Naima El Hafidi

{"title":"Pediatric pycnodysostosis complicated by severe obstructive sleep apnea: a case report.","authors":"Islam Tarik, Farah Makhloufi, Chafiq Mahraoui, Naima El Hafidi","doi":"10.1093/omcr/omag141","DOIUrl":"10.1093/omcr/omag141","url":null,"abstract":"Background: Pycnodysostosis is a rare genetic bone disorder linked to mutations in the CTSK gene, which causes osteoclast dysfunction. We report the case of a child with pycnodysostosis complicated by severe obstructive sleep apnea syndrome (OSAS).Case presentation: The patient was a 9-years-old girl born to consanguineous parents. Clinical examination revealed short stature, characteristic facial features, acromicria, and several skeletal abnormalities. X-rays revealed diffuse osteosclerosis associated with bone abnormalities characteristic of pycnodysostosis. Polysomnography confirmed severe OSA, with an apnea-hypopnea index (AHI) of 49.8 events per hour.Conclusion: This observation highlights the association between pycnodysostosis and nocturnal respiratory impairment, and underscores the importance of systematic screening for sleep-disordered breathing by polysomnography in these patients. Management is based on a multidisciplinary approach and long-term follow-up in order to optimize the functional prognosis and quality of life of patients and their families.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag141"},"PeriodicalIF":0.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pasteurella dagmatis prosthetic valve endocarditis with suspected mycotic aortic aneurysm: a case report. 假体瓣膜心内膜炎合并疑似真菌性主动脉瘤1例。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-12 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag126

Qais Akasheh, Tania Lasrado, Paul Carter, John Li

引用次数: 0

VEXAS syndrome presenting with severe cutaneous manifestations, inflammatory arthritis, and myelodysplastic syndrome treated with Ruxolitinib. 以严重皮肤表现、炎症性关节炎和骨髓增生异常综合征为表现的VEXAS综合征用Ruxolitinib治疗。

IF 0.6

Oxford Medical Case Reports Pub Date : 2026-07-12 eCollection Date: 2026-07-01 DOI: 10.1093/omcr/omag121

Jared Tesch, Nada Alrifai, Beth Honl, Siddharth Singhal

引用次数: 0