Oxford Medical Case Reports最新文献

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Aggressive management and liver transplantation in Budd-Chiari syndrome secondary to Behçet's disease. behet病继发Budd-Chiari综合征的积极治疗和肝移植。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-08-11 eCollection Date: 2025-08-01 DOI: 10.1093/omcr/omaf126
Ali Bani Odah, Zaid Sawaftah, Ammar Hassouneh, Ameer Awashra, Ahmad Hamdan, Fathi Milhem, Ahmed Sawafta, Omar Sawafta, Jehad Khamaysa, Nader Sarhan, Yazan Ghannam
{"title":"Aggressive management and liver transplantation in Budd-Chiari syndrome secondary to Behçet's disease.","authors":"Ali Bani Odah, Zaid Sawaftah, Ammar Hassouneh, Ameer Awashra, Ahmad Hamdan, Fathi Milhem, Ahmed Sawafta, Omar Sawafta, Jehad Khamaysa, Nader Sarhan, Yazan Ghannam","doi":"10.1093/omcr/omaf126","DOIUrl":"10.1093/omcr/omaf126","url":null,"abstract":"<p><p>Budd-Chiari Syndrome (BCS) is a rare vascular disorder caused by hepatic venous outflow obstruction, often due to thrombosis, leading to liver congestion and portal hypertension. Behçet's Disease (BD), a chronic vasculitis, can cause BCS through inflammation-induced thrombosis. We report a 14-year-old male with BD who developed BCS. He initially presented with foot pain, uveitis, and a bilateral rash, later progressing to abdominal distension, jaundice, and hepatic dysfunction. Investigations revealed elevated transaminases and hyperbilirubinemia, with imaging confirming hepatic vein thrombosis. Management included corticosteroids, immunosuppressants, and anticoagulation. Despite treatment, liver function deteriorated, necessitating a transplant, after which he stabilized with significant symptomatic improvement. This case underscores the need for early recognition of BD-related vascular complications, timely intervention to prevent irreversible liver damage, and consideration of liver transplantation in severe BCS. Increased awareness of BD as a potential cause of BCS is crucial for prompt diagnosis and management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 8","pages":"omaf126"},"PeriodicalIF":0.4,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An 80-year-old female with multiple mononeuropathy: neuroleukemiosis a rare complication of chronic lymphocytic leukaemia. 一例80岁女性多发性单神经病变:神经白血病是慢性淋巴细胞白血病的罕见并发症。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-08-11 eCollection Date: 2025-08-01 DOI: 10.1093/omcr/omaf131
Caroline Morgan, Venkataramanan Srinivasan, Ute Pohl, Benjamin R Wakerley
{"title":"An 80-year-old female with multiple mononeuropathy: neuroleukemiosis a rare complication of chronic lymphocytic leukaemia.","authors":"Caroline Morgan, Venkataramanan Srinivasan, Ute Pohl, Benjamin R Wakerley","doi":"10.1093/omcr/omaf131","DOIUrl":"10.1093/omcr/omaf131","url":null,"abstract":"<p><p>We report the case of an 80-year-old lady with chronic lymphocytic leukaemia who presented with painful footdrop. Nerve conduction studies and electromyography confirmed the presence of multiple mononeuropathy. Left superficial radial nerve biopsy revealed small lymphocytes infiltrating the epineurium and perineurium and confirmed a diagnosis of neuroleukemiosis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 8","pages":"omaf131"},"PeriodicalIF":0.4,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From oral erosions to lymphoma: a case of paraneoplastic pemphigus with occult lymphoma. 从口腔糜烂到淋巴瘤:副肿瘤天疱疮伴隐匿性淋巴瘤1例。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-08-11 eCollection Date: 2025-08-01 DOI: 10.1093/omcr/omaf124
Kumari Monalisa, Tanvi Dev, Vaishnavi Modi, Akarshi Gupta, Varuna Mallya, Rashmi Dixit
{"title":"From oral erosions to lymphoma: a case of paraneoplastic pemphigus with occult lymphoma.","authors":"Kumari Monalisa, Tanvi Dev, Vaishnavi Modi, Akarshi Gupta, Varuna Mallya, Rashmi Dixit","doi":"10.1093/omcr/omaf124","DOIUrl":"10.1093/omcr/omaf124","url":null,"abstract":"<p><p>A 67-year-old female with type-2 diabetes mellitus presented with recalcitrant painful oral erosions and violaceous chest lesions, that responded minimally to oral corticosteroids. Due to history of decreased appetite, weight loss and poor therapeutic response, further evaluation was performed, revealing elevated C-Reactive Peptide, Desmoglein-3 antibody, Carbohydrate Antigen 19-9, and intraperitoneal lobulated homogeneously enhancing nodal mass, the latter indicating lymphoma. Histopathology from oral mucosa was suggestive of paraneoplastic pemphigus. The patient was referred to oncology department for further management. This case underscores the importance of thorough evaluation in elderly patients with recalcitrant mucocutaneous lesions with atypical histopathology.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 8","pages":"omaf124"},"PeriodicalIF":0.4,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aortic dissection presenting with Hemoptysis: a diagnostic challenge. 主动脉夹层表现为咯血:一个诊断挑战。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-07-27 eCollection Date: 2025-07-01 DOI: 10.1093/omcr/omaf107
Ahmad Alashqar, Mohammad Alashqar, Ahmad Daraghmeh, Hala A I Dalbah, Mohammed I Abu Kamesh, Yazan Giacaman, Salma Hajj-Qasem
{"title":"Aortic dissection presenting with Hemoptysis: a diagnostic challenge.","authors":"Ahmad Alashqar, Mohammad Alashqar, Ahmad Daraghmeh, Hala A I Dalbah, Mohammed I Abu Kamesh, Yazan Giacaman, Salma Hajj-Qasem","doi":"10.1093/omcr/omaf107","DOIUrl":"10.1093/omcr/omaf107","url":null,"abstract":"<p><p>Hemoptysis is the expectoration of blood originating from the lower respiratory tract and has a wide differential diagnosis, ranging from benign conditions to life-threatening diseases that include pulmonary embolism, severe infections, and aortic dissection. We present a 53-year-old male with a history of hypertension, COPD, and smoking, presenting to the emergency department with a two-day history of hemoptysis. In spite of the absence of classical symptoms such as chest pain, his chest X-ray showed mediastinal widening, and further imaging was performed with contrast-enhanced CT angiography. The CT scan confirmed a Stanford Type B aortic dissection. After multidisciplinary review, medical management was decided upon with antihypertensive medications and tranexamic acid. The patient remained hemodynamically stable and was transferred for further management. This case indicates the inclusion of aortic dissection in the differential diagnosis of hemoptysis, even without classic symptoms.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf107"},"PeriodicalIF":0.4,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report: may-Thurner syndrome: early diagnosis and intervention in a young healthy woman. 病例报告:梅-瑟纳综合征:早期诊断和干预在一个年轻的健康妇女。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-07-27 eCollection Date: 2025-07-01 DOI: 10.1093/omcr/omaf108
Zishan Rahman, Palvi Mroke, Saba Tariq, Naveed Khan, Fatima Tariq, Ernesto Calderon Martínez, Imran Baig
{"title":"Case report: may-Thurner syndrome: early diagnosis and intervention in a young healthy woman.","authors":"Zishan Rahman, Palvi Mroke, Saba Tariq, Naveed Khan, Fatima Tariq, Ernesto Calderon Martínez, Imran Baig","doi":"10.1093/omcr/omaf108","DOIUrl":"10.1093/omcr/omaf108","url":null,"abstract":"<p><p>May-Thurner Syndrome (MTS) is caused by left common iliac vein compression, resulting in deep vein thrombosis (DVT). MTS is usually asymptomatic until DVT occurs. Our case features a 37-year-old woman who presented with swelling and pain in her left leg after recent travel and oral contraceptive use. Venous duplex ultrasound confirmed DVT and CT angiogram excluded pulmonary embolism. She received Heparin anticoagulation and underwent mechanical thrombectomy and stenting. Her symptoms improved within two days, and she was discharged on Apixaban and Plavix. This case involves a unique patient presentation of MTS, involving young woman with unexplained left-sided DVT, a scenario typically seen in older patients with clotting disorders.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf108"},"PeriodicalIF":0.4,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ruptured intracranial Mycotic aneurysm following infective endocarditis in a young patient: a case report. 年轻患者感染性心内膜炎后颅内真菌性动脉瘤破裂1例报告。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-07-27 eCollection Date: 2025-07-01 DOI: 10.1093/omcr/omaf109
Hind Neiroukh, Hanin Shatrit, Sarmad Sultan, Sarah Warasna, Maher Aljodi, Tharwat Aljodi
{"title":"Ruptured intracranial Mycotic aneurysm following infective endocarditis in a young patient: a case report.","authors":"Hind Neiroukh, Hanin Shatrit, Sarmad Sultan, Sarah Warasna, Maher Aljodi, Tharwat Aljodi","doi":"10.1093/omcr/omaf109","DOIUrl":"10.1093/omcr/omaf109","url":null,"abstract":"<p><p>Mycotic aneurysms (MAs) are a rare but life-threatening complication of infective endocarditis (IE), resulting from septic emboli lodging in cerebral vessels and leading to aneurysm formation. This case report describes a 17-year-old female who developed multiple MAs during treatment for IE, resulting in catastrophic neurological decline and eventual death. After undergoing open-heart surgery for vegetation excision, our patient then developed intracranial bleeding due to mycotic aneurysms rupture, which led to her death after an unsuccessful decompressive craniotomy. This case highlights the importance of early recognition and timely intervention in the management of MAs in the context of IE, as well as the need for protocols to improve outcomes in these high-risk patients. The high mortality rate associated with ruptured MAs highlights the critical nature of these complications and the challenges in their management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf109"},"PeriodicalIF":0.4,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silent misplacement: leadless pacemaker in the left ventricle discovered over a year later-How did it end up there? Could it explain the stroke? 无声错位:一年多后发现左心室无导联起搏器——它是如何在那里结束的?这能解释中风吗?
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-07-27 eCollection Date: 2025-07-01 DOI: 10.1093/omcr/omaf117
Abdalhakim Shubietah, Amir Singh, Qutaiba Qafisheh, Pouyan Razminia, Muath Baniowda, Abdalrahman Assaassa, Hosam I Taha, Roaa Aljunaidi
{"title":"Silent misplacement: leadless pacemaker in the left ventricle discovered over a year later-How did it end up there? Could it explain the stroke?","authors":"Abdalhakim Shubietah, Amir Singh, Qutaiba Qafisheh, Pouyan Razminia, Muath Baniowda, Abdalrahman Assaassa, Hosam I Taha, Roaa Aljunaidi","doi":"10.1093/omcr/omaf117","DOIUrl":"10.1093/omcr/omaf117","url":null,"abstract":"<p><p><b>Introduction</b>: Leadless intracardiac pacemakers (LICPs) reduce lead-related complications but may be malpositioned in patients with unrecognized structural defects. We report a 69-year-old man with high-grade AV block whose LICP, intended for right ventricular placement, was found in the left ventricle via an undiagnosed ostium secundum ASD after presenting with multifocal embolic strokes 16 months later. <b>Case Presentation</b>: Stroke workup for acute right-sided symptoms revealed the LICP in the LV and a large, previously undiagnosed ASD with bidirectional shunting and severe pulmonary hypertension. Embolic infarcts were attributed to either paradoxical embolism or device-related thromboembolism. Due to high surgical risk, the device was left in place; heparin was started with plans to bridge to warfarin. The patient later declined percutaneous ASD closure. <b>Conclusion</b>: This case highlights the risk of LICP misplacement via an unrecognized ASD and underscores the need for structural evaluation before implantation, even without clinical suspicion.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf117"},"PeriodicalIF":0.4,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imported case of cholera from India: the first recorded in Bulgaria in over a century. 从印度输入的霍乱病例:保加利亚一个多世纪以来首次记录。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-07-27 eCollection Date: 2025-07-01 DOI: 10.1093/omcr/omaf113
Ralitsa Yordanova, Eugeni Pentchev
{"title":"Imported case of cholera from India: the first recorded in Bulgaria in over a century.","authors":"Ralitsa Yordanova, Eugeni Pentchev","doi":"10.1093/omcr/omaf113","DOIUrl":"10.1093/omcr/omaf113","url":null,"abstract":"<p><p>Cholera is an acute bacterial infection characterized by profuse watery diarrhea, vomiting, and dehydration, potentially leading to severe complications and death. It remains endemic in regions with poor sanitation and limited access to clean water, particularly in South and Southeast Asia and parts of Africa. In Europe, only sporadic cases are reported annually, and are typically imported by travelers returning from endemic areas. Mild cases often present with non-specific gastrointestinal symptoms, making them clinically indistinguishable from other enteric infections. To initiate appropriate epidemiological measures and prevent transmission in non-endemic regions, cholera should be considered in any case of acute watery diarrhea in individuals with a recent travel history to endemic areas. We report a case of cholera in a patient returning from India-the first recorded in Bulgaria in over a century.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf113"},"PeriodicalIF":0.4,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Langerhans cell histiocytosis disguised as lichenoid eruption. 朗格汉斯细胞组织细胞增多症伪装成地衣样疹。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-07-27 eCollection Date: 2025-07-01 DOI: 10.1093/omcr/omaf106
Ashjan Alheggi
{"title":"Langerhans cell histiocytosis disguised as lichenoid eruption.","authors":"Ashjan Alheggi","doi":"10.1093/omcr/omaf106","DOIUrl":"10.1093/omcr/omaf106","url":null,"abstract":"<p><p>Langerhans cell histiocytosis (LCH) is an inflammatory clonal proliferative neoplasm of immature myeloid precursor cells. These cells can accumulate in various tissues including skin, leading to tissue damage, and in some cases organ dysfunction. Herein, a report of a 1-year-old girl who presented with multiple lichenoid pinkish to purplish flat-topped papules, some of them were crusted and linear over the trunk mimicking lichen planus. The histopathologic and immunohistochemical staining confirmed the diagnosis of LCH. Awareness about this rare entity is important for early detection, timely intervention, and effective management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf106"},"PeriodicalIF":0.4,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Schnitzler syndrome - a rare cause of chronic urticaria. Case report. 施尼茨勒综合征——一种罕见的慢性荨麻疹病因。病例报告。
IF 0.4
Oxford Medical Case Reports Pub Date : 2025-07-27 eCollection Date: 2025-07-01 DOI: 10.1093/omcr/omaf118
Łukasz Moos, Aleksandra Kułakowska, Dorota Szydłowska, Weronika Chodak, Zenon Brzoza
{"title":"Schnitzler syndrome - a rare cause of chronic urticaria. Case report.","authors":"Łukasz Moos, Aleksandra Kułakowska, Dorota Szydłowska, Weronika Chodak, Zenon Brzoza","doi":"10.1093/omcr/omaf118","DOIUrl":"10.1093/omcr/omaf118","url":null,"abstract":"<p><p>Schnitzler syndrome (SchS) is a very rare acquired systemic disease that has many similarities to hereditary autoinflammatory syndromes. The condition is characterized by the presence of monoclonal gammopathy and chronic urticaria. In this case report, a 64-year-old male patient with SchS was initially misdiagnosed with chronic spontaneous urticaria (CSU). The patient was treated with anakinra, showing good tolerance and no need for steroid therapy for 14 months. SchS is often underdiagnosed and presents symptoms such as prolonged urticarial wheals and systemic manifestations. The differential diagnoses include mastocytosis, urticarial vasculitis, and autoimmune diseases. The diagnostic criteria were elevated CRP levels, neutrophilic skin infiltration, leukocytosis, and abnormal bone remodeling on scintigraphy. Treatment options include highly effective interleukin-1 blockade therapies such as anakinra, canakinumab, and rilonacept. This case emphasizes the importance of a thorough differential diagnosis of chronic urticaria and encourages clinicians to participate in the SchS database for improved recognition and management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf118"},"PeriodicalIF":0.4,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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