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Paradoxical coronary embolism in Erdheim-Chester disease: invasive assessment and multidisciplinary management. 埃尔德海姆-切斯特病患者的并发冠状动脉栓塞：侵入性评估和多学科管理。
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae163
Vasileios Lamprou, Matthew J Daniels, Charles D Read, Freidoon Keshavarzi
{"title":"Paradoxical coronary embolism in Erdheim-Chester disease: invasive assessment and multidisciplinary management.","authors":"Vasileios Lamprou, Matthew J Daniels, Charles D Read, Freidoon Keshavarzi","doi":"10.1093/omcr/omae163","DOIUrl":"10.1093/omcr/omae163","url":null,"abstract":"<p><p>We report a case of non-ST elevation myocardial infarction in a 36-year-old man with Erdheim-Chester disease (ECD). Multimodality assessment revealed acute coronary thrombus with simultaneous recurrent pulmonary embolism in spite of compliance with a direct oral anticoagulant. Prior case reports of acute myocardial infarction in this population have not outlined the role of catheter based intravascular assessment and treatment in this rare clinical entity.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae163"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe restenosis after stentless treatment with coronary intravascular lithotripsy for calcified nodule lesions: a serial observation with IVUS.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae156
Rina Konishi, Akinori Higaki, Toru Miyoshi, Kazuhisa Nishimura, Shuntaro Ikeda, Osamu Yamaguchi
{"title":"Severe restenosis after stentless treatment with coronary intravascular lithotripsy for calcified nodule lesions: a serial observation with IVUS.","authors":"Rina Konishi, Akinori Higaki, Toru Miyoshi, Kazuhisa Nishimura, Shuntaro Ikeda, Osamu Yamaguchi","doi":"10.1093/omcr/omae156","DOIUrl":"10.1093/omcr/omae156","url":null,"abstract":"<p><p>An 82-year-old woman with a history of myocardial infarction presented with worsening effort angina. Coronary angiography (CAG) revealed 75% stenosis in the proximal left anterior descending artery (LAD), with intravascular ultrasound (IVUS) identifying a severe calcified nodule near a previously implanted drug-eluting stent. The lesion was treated with intravascular lithotripsy (IVL) and a drug-coated balloon (DCB), avoiding left main crossover stenting. Despite initial success, the patient experienced restenosis three months later, managed conservatively based on favorable DFR/FFR values. However, worsening symptoms led to repeat CAG, revealing 99% restenosis with calcified nodule. A second IVL was performed, followed by crossover stenting from the left main to the LAD, achieving successful stent expansion. This case underscores the potential for severe restenosis following IVL and DCB angioplasty, highlighting the limitations of IVL in reducing calcified plaque volume and the importance of close follow-up.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae156"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metacarpophalangeal joint arthritis in IgA vasculitits.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae157
Yamato Hanawa, Hiroyuki Namba
{"title":"Metacarpophalangeal joint arthritis in IgA vasculitits.","authors":"Yamato Hanawa, Hiroyuki Namba","doi":"10.1093/omcr/omae157","DOIUrl":"10.1093/omcr/omae157","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae157"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumour in the dark: a challenging case of osteomalacia.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae159
Robert Ambrogetti, Omer Taha, Mohamed Saeed, Prashanth Patel, Faizanur Rahman
{"title":"Tumour in the dark: a challenging case of osteomalacia.","authors":"Robert Ambrogetti, Omer Taha, Mohamed Saeed, Prashanth Patel, Faizanur Rahman","doi":"10.1093/omcr/omae159","DOIUrl":"10.1093/omcr/omae159","url":null,"abstract":"<p><p>Tumour-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is a rare paraneoplastic syndrome mediated by the overproduction of phosphaturic hormone fibroblast growth factor 23. TIO is most commonly caused by mesenchymal tumours (PMTs), which are typically small, slow-growing and often undetectable on physical examination and conventional imaging techniques. Patients with TIO typically undergo a protracted period of diagnostic workup and medical treatment due to presentation with nonspecific symptoms and difficulty in localising the culprit tumour. During this period, ongoing surveillance is imperative as medical treatment can limit symptom progression, and tumour identification can provide definitive treatment. We report a case of TIO secondary to a PMT, which, despite biochemical diagnosis, medical treatment and serial imaging, took approximately ten years for tumour localisation.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae159"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatocellular carcinoma converted from atezolizumab and bevacizumab combination therapy: a case report.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae155
Keisuke Ida, Satoshi Koizumi, Atsuhito Tsuchihashi, Shinjiro Kobayashi, Takehito Otsubo
{"title":"Hepatocellular carcinoma converted from atezolizumab and bevacizumab combination therapy: a case report.","authors":"Keisuke Ida, Satoshi Koizumi, Atsuhito Tsuchihashi, Shinjiro Kobayashi, Takehito Otsubo","doi":"10.1093/omcr/omae155","DOIUrl":"10.1093/omcr/omae155","url":null,"abstract":"<p><p>Hepatectomy is the curative treatment for hepatocellular carcinoma (HCC), with targeted therapy used when resection is difficult. In this rare case, the tumor shrank with targeted therapy, enabling radical treatment through conversion surgery. The patient, a man in his 70s, developed an 11.5-cm HCC (T3N0M0 Stage III) in the posterior hepatic zone after being virologically negative for hepatitis C. The tumor was near the right portal vein branch, making the liver lobe unresectable due to poor liver function. Upon tumor enlargement, he was treated with atezolizumab and bevacizumab. After 5 courses, the tumor significantly shrank, allowing for complete resection with posterior segment removal. The surgery revealed mostly necrotic tumors with no active cancer cells remaining.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae155"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report. 脾脏硬化性血管瘤样结节变（SANT）：病例报告。
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae158
Sotiris Loizides, Paraskevi Samouti, George Tsironis, Eleni Xenophontos, Demetrios Papamichael, Vassilios Vassiliou
{"title":"Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report.","authors":"Sotiris Loizides, Paraskevi Samouti, George Tsironis, Eleni Xenophontos, Demetrios Papamichael, Vassilios Vassiliou","doi":"10.1093/omcr/omae158","DOIUrl":"10.1093/omcr/omae158","url":null,"abstract":"<p><p>SANT is a rare, non-lymphoid, benign entity, originating from the red pulp of the spleen. It is characterized by the presence of vascular nodules surrounded by a stroma of collagen fibers. It was introduced as a distinct disease entity by Martel et al in 2004, after the histopathological examination of 25 cases. Symptoms are unspecific, and in most cases, it is incidentally diagnosed, mostly in patients who undergo imaging for other underlying conditions. Moreover, radiological findings are usually inconclusive, and a definite diagnosis is established through histopathological examination. We herein report the case of a 76-year-old female diagnosed with stage I rectal cancer who was subsequently diagnosed with a splenic lesion after a Computed Tomography (CT) scan that was performed for follow-up purposes. Different imaging modalities were employed for further assessment; however, findings were inconclusive and the possibility of metastatic disease could not be excluded. The patient was referred for splenectomy and the diagnosis of SANT was established through histopathological examination.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae158"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LGI1 encephalitis manifesting as a delayed paraneoplastic response of squamous cell lung cancer on remission.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae171
Ikechukwu Chukwuocha, Baig Al-Moyeed, Solomon Eigbe, Shilpi Shukla
{"title":"LGI1 encephalitis manifesting as a delayed paraneoplastic response of squamous cell lung cancer on remission.","authors":"Ikechukwu Chukwuocha, Baig Al-Moyeed, Solomon Eigbe, Shilpi Shukla","doi":"10.1093/omcr/omae171","DOIUrl":"10.1093/omcr/omae171","url":null,"abstract":"<p><p>The leucine-rich glioma-inactivated protein 1 (LGI1) antibody-related autoimmune encephalitis can occur alone or in the setting of a malignancy and manifest with faciobrachial dystonic seizures (FBDS), cognitive decline, hyponatremia, and neuropsychiatric disorders. The importance of differentiating this entity from acute delirium cannot be overemphasized. This review provides a detailed account of a 71-year-old man with previous diagnosis of lung cancer who presented with subacute onset behavioural changes, urinary retention, and FBDS. Investigation revealed hyponatremia, bilateral mesial temporal lobe high signal abnormality worse on the right on MRI and CSF positive anti-LGI1 antibodies (1:30). The patient was treated with immunosuppressive therapy with consequent symptom improvement. This case emphasizes the need to have a high index of suspicion for this disease entity in patients presenting with new onset behavioural changes and the importance of identifying the typical FBDS, as early initiation of treatment confers a positive outcome for diseased patients.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae171"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mimicking myocardial infarction: a subarachnoid haemorrhage case report.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-28 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae154
Ezzat Mohammed Hussain Aziz, Ahmed Qasim Mohammed Alhatemi, Hashim Talib Hashim, Amir Salam Khaleel
{"title":"Mimicking myocardial infarction: a subarachnoid haemorrhage case report.","authors":"Ezzat Mohammed Hussain Aziz, Ahmed Qasim Mohammed Alhatemi, Hashim Talib Hashim, Amir Salam Khaleel","doi":"10.1093/omcr/omae154","DOIUrl":"10.1093/omcr/omae154","url":null,"abstract":"<p><p>We present a case detailing the diagnostic challenges of a 23-year-old male presenting with a sudden severe headache, nausea, vomiting, and chest heaviness. Initial evaluation showed elevated blood pressure and respiratory rate. An emergency electrocardiogram (ECG) indicated ST-segment elevation myocardial infarction (STEMI), leading to immediate referral for percutaneous coronary intervention, which revealed normal coronary arteries. Further investigations identified a cisternal subarachnoid haemorrhage (SAH) on CT brain imaging. Despite multidisciplinary management, the patient's condition rapidly deteriorated, resulting in cardiac arrest and mortality. Our case highlights the importance of thorough evaluation and multidisciplinary collaboration in managing complex presentations, emphasizing vigilance in recognizing and managing concurrent pathologies in young patients with acute symptoms.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae154"},"PeriodicalIF":0.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linezolid induced acute toxic leukoencephalopathy and severe thrombocytopenia presenting as stroke mimic-a case report.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-10 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae150
S Ahmed, G Hayman, S Moin, H Ubaide, R Sivakumar, J Padayatty
{"title":"Linezolid induced acute toxic leukoencephalopathy and severe thrombocytopenia presenting as stroke mimic-a case report.","authors":"S Ahmed, G Hayman, S Moin, H Ubaide, R Sivakumar, J Padayatty","doi":"10.1093/omcr/omae150","DOIUrl":"10.1093/omcr/omae150","url":null,"abstract":"<p><p>A 67-year-old lady was admitted with, right sided weakness and right arm shaking. She had recently completed a course of Linezolid for a diabetic foot infection and osteomyelitis. Prior to this she had prodromal symptoms including lethargy and loss of appetite. Clinical features prompting presentation included global weakness, verbal dysfluency and visual disturbance. MRI brain showed bilateral alteration of signal in the deep white matter of the posterior frontal and parietal lobes, sparing the superficial cortical areas. These areas showed diffusion restriction, suggestive of, but not limited to, ischaemic stroke. During admission she had a decline in consciousness and was hypertensive. An acute drop in haemoglobin and platelets occurred prompting consideration of Thrombotic Microangiopathy and other drug related/malignant/infective aetiologies. A diagnosis of Linezolid induced Acute Toxic Leukoencephalopathy and thrombocytopenia was made based on clinico-radiographic features and exclusion of other causes.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae150"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A super-giant basal cell carcinoma of the scalp.
IF 0.5
Oxford Medical Case Reports Pub Date : 2024-12-10 eCollection Date: 2024-12-01 DOI: 10.1093/omcr/omae149
Alexandros Patsouras, Nikolaos Garmpis, Eleni I Effraimidou, Dimitrios Dimitroulis, Dimitrios Papoutsas, Iason Psilopatis, Anna Garmpi, Evangelos Diamantis, Kleio Vrettou, Sampaziotis Dimitrios, Paraskevi Ioanna Tasioula, Christos Damaskos
{"title":"A super-giant basal cell carcinoma of the scalp.","authors":"Alexandros Patsouras, Nikolaos Garmpis, Eleni I Effraimidou, Dimitrios Dimitroulis, Dimitrios Papoutsas, Iason Psilopatis, Anna Garmpi, Evangelos Diamantis, Kleio Vrettou, Sampaziotis Dimitrios, Paraskevi Ioanna Tasioula, Christos Damaskos","doi":"10.1093/omcr/omae149","DOIUrl":"10.1093/omcr/omae149","url":null,"abstract":"<p><p>Basal cell carcinoma is a malignant skin cancer, originating from basal cells. However, it is regarded more benign than other skin cancers, in the majority of the cases. If left untreated, it can lead to various complications, degradation of quality of life and even mortality to the patient. A basal cell carcinoma with one dimension more than 20 cm, is defined as super-giant. In this report, we present a case of a super-giant basal cell carcinoma occupying most of the scalp in an elderly patient, causing him severe anemia and general malaise.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae149"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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