{"title":"Hemolytic uremic syndrome in severe acute pancreatitis.","authors":"Jayaraj Hasvi, Inder Preet Singh Bhatia, Saurabh Dawra, Amulyajit Singh, Siddharth Tripathi","doi":"10.1093/omcr/omaf048","DOIUrl":"10.1093/omcr/omaf048","url":null,"abstract":"<p><strong>Introduction: </strong>Hemolytic Uremic Syndrome is characterized by Coombs negative microangiopathic hemolytic anemia, severe thrombocytopenia, and acute kidney injury.</p><p><strong>Case report: </strong>Here, we report a 36-year-old male, a case of alcohol related acute pancreatitis. On day 5, he developed fever and tachycardia. Evaluation revealed thrombocytopenia, hemolytic anemia, and acute kidney injury with low C3, normal C4 & ADAMTS13 activity and positive anti-complement factor H antibody. He was diagnosed as a case of Hemolytic Uremic Syndrome and managed with plasmapheresis, hemodialysis, and Intravenous immunoglobulin. He was administered Rituximab on day 15, considering the refractory nature of the disease. Despite the aggressive management, he succumbed to his illness.</p><p><strong>Conclusion: </strong>This case highlights atypical Hemolytic Uremic Syndrome as a rare complication of Acute Pancreatitis. Our patient, despite being diagnosed well in time and managed aggressively, had an unfavourable outcome. This condition should be diagnosed well in time, as it is associated with high mortality.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf048"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First case report of multidrug-resistant <i>Tatumella ptyseos</i> causing surgical site infection in Tanzania.","authors":"Anthon Mwingwa, Aminiel Shangali, Elieshiupendo Niccodem, Sabah Dewji, Sandra Sillas, Agricola Joachim, Mtebe Majigo","doi":"10.1093/omcr/omaf052","DOIUrl":"10.1093/omcr/omaf052","url":null,"abstract":"<p><p>A 53-year-old man developed a surgical site infection after undergoing a pylorus-preserving pancreaticoduodenectomy despite receiving preventive antibiotics. The infection was linked to <i>Tatumella ptyseos</i>, a rare and multidrug-resistant gram-negative bacterium from the Enterobacterales order, which mainly affects immunocompromised individuals. Identifying the pathogen proved challenging; standard biochemical tests did not provide conclusive results, necessitating the use of the Analytical Profile Index and a specialized biochemical panel for Enterobacterales. This case marks the first documented occurrence of multidrug-resistant <i>T. ptyseos</i> causing a surgical site infection in Tanzania. It underscores the rising presence of uncommon pathogens in healthcare settings and emphasizes the need for enhanced diagnostic methods and infection control strategies, especially in resource-limited environments where antibiotic resistance presents significant challenges.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf052"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Sharif Sediqi, Mansoor Aslamzai, Abdulhakim Mukhlis, Khesrow Ekram
{"title":"Gallbladder ascariasis in Kabul-focus on ultrasound and conservative therapy: a case report.","authors":"Mohammad Sharif Sediqi, Mansoor Aslamzai, Abdulhakim Mukhlis, Khesrow Ekram","doi":"10.1093/omcr/omaf040","DOIUrl":"10.1093/omcr/omaf040","url":null,"abstract":"<p><p>The most frequent human intestinal nematode is <i>Ascaris lumbricoides</i>. Ascariasis is one of the most prevalent intestinal illnesses in underdeveloped nations, including Afghanistan. It affects over 25% of the world's population and causes about 20 000 fatalities annually due to its unfavorable clinical course. In endemic locations, 50%-60% of pediatric admissions to surgical emergency rooms are caused by <i>A. lumbricoides.</i> Due to the cystic duct's narrowness and tortuousness, migration of the worm to the gallbladder is less common than migration to the bile duct. When it does, acalculous cholecystitis is triggered. We report the case of a three year old girl presenting with abdominal pain, fever and vomiting. Laboratory tests revealed eosinophilia and elevated liver enzymes. Ultrasound examination identified a live <i>Ascaris</i> worm in the gallbladder. The patient was treated successfully with anti-helminthic therapy, resulting in symptom resolution.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf040"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Focal fatty infiltration of the lumbar intervertebral disc: a case report and literature review.","authors":"Shritik Devkota, Hritika Rathi, Samiksha Lamichhane","doi":"10.1093/omcr/omaf027","DOIUrl":"10.1093/omcr/omaf027","url":null,"abstract":"<p><p>An intervertebral disc is a pliable, cushioning structure present between the vertebrae in the spine. It functions as a shock absorber, minimizing friction and facilitating movement between the spinal bones. Degenerative changes are viewed as responses to injuries, whether mechanical or metabolic, rather than as distinct diseases. Degenerative disc disease is a frequent etiology of low back pain. Magnetic resonance imaging (MRI) commonly demonstrates disc desiccation, degeneration, herniation or protrusion, osteophyte formation, and facet joint arthropathy. In this case report we have specifically addressed a component of degenerative disc disease which is seen as an uncommon MRI finding of focal intradiscal fat. Although the direct impact of focal intradiscal fat on patient outcomes is not fully understood, it typically indicates advanced disc degeneration. Recognizing this finding can assist clinicians in diagnosing the extent of disc degeneration and developing appropriate treatment plans for patients with low back pain or related symptoms.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf027"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Limbal stem cell deficiency: a dreaded complication of chickenpox in children.","authors":"Oumayma Elmansouri, Assia Lemkhoudem, Houda Bezza, Houssaine Ait Lhaj, Mohamed Kriet, Fouad Elasri","doi":"10.1093/omcr/omaf037","DOIUrl":"10.1093/omcr/omaf037","url":null,"abstract":"<p><p>We report a rare case of Limbal Stem Cell Deficiency (LSCD) in a 10-year-old child following chickenpox. The child presented with persistent ocular symptoms, including pain, redness, and photophobia, two months after the resolution of systemic chickenpox. Ophthalmic examination revealed conjunctival hyperemia, 360° conjunctivalization, corneal neovascularization, and an epithelial defect. LSCD, characterized by corneal neovascularization and conjunctivalization, can occur after viral infections, including herpes zoster. To our knowledge, this is the first reported case of LSCD following chickenpox in a child. Early recognition and collaborative care between pediatricians and ophthalmologists are essential for effective management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf037"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A fatal case of cytomegalovirus pneumonia with coexisting <i>aspergillus</i> infection in a immunodeficient patient.","authors":"Kunlun Huang, Shaosen Chen","doi":"10.1093/omcr/omaf060","DOIUrl":"10.1093/omcr/omaf060","url":null,"abstract":"<p><p><b>Introduction</b>: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging. <b>Patient concerns</b>: The patient was an older woman with low immune function but was not a transplant patient. <b>Diagnosis</b>: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia. <b>Interventions</b>: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment. <b>Outcome</b>: The patient's condition deteriorated and she eventually died of myocardial infarction. <b>Conclusion</b>: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf060"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Zuhair, Samuel Seitler, Nandita Kaza, Phang Boon Lim, Daniel Keene, Raj Khiani
{"title":"Yoga in the emergency room: termination of SVT with the Child's pose.","authors":"Mohamed Zuhair, Samuel Seitler, Nandita Kaza, Phang Boon Lim, Daniel Keene, Raj Khiani","doi":"10.1093/omcr/omaf049","DOIUrl":"10.1093/omcr/omaf049","url":null,"abstract":"<p><p>We present the case of a 27-year-old woman who has successfully self-managed her supraventricular tachycardia (SVT) episodes since her teenage years using the Child's Pose, a technique adapted from yoga. This non-pharmacological approach enabled her to independently terminate SVT episodes, a capability confirmed in a controlled clinical setting where the patient's return to sinus rhythm was immediately achieved upon assuming the pose. The Child's Pose represents a solitary and patient-empowering intervention, contrasting with the assistance-dependent modified Valsalva manoeuvre. This case demonstrates the potential for yoga-influenced practices in the personalized management of cardiac arrhythmias.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf049"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revisiting coronary artery-cameral vessels: clarifying 'MICROFISTULAE' and moving beyond eponymous terms.","authors":"Brett Thomas Snodgrass","doi":"10.1093/omcr/omaf044","DOIUrl":"10.1093/omcr/omaf044","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf044"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erum Ilyas, Muhammad Affan, Razia Iftikhar, Khabab Abbasher Hussien Mohamed Ahmed
{"title":"A familial case of VACTERL association with co-occurring sacrococcygeal teratoma: a case report.","authors":"Erum Ilyas, Muhammad Affan, Razia Iftikhar, Khabab Abbasher Hussien Mohamed Ahmed","doi":"10.1093/omcr/omaf046","DOIUrl":"10.1093/omcr/omaf046","url":null,"abstract":"<p><strong>Background: </strong>VACTERL association is a rare disorder characterized by a non-random co-occurrence of multiple congenital anomalies. Reported incidences of VACTERL are usually sporadic.</p><p><strong>Case presentation: </strong>Here we present a case of familial VACTERL association in a male infant born full term at 38 weeks of gestation. The infant's maternal aunt also had significant features of VACTERL association but died in the first year of life. Due to the lack of specialized expertise and absence of detailed anomaly scans, the congenital anomalies were not detected prenatally. The baby also had a very rare co-occurrence of sacrococcygeal teratoma.</p><p><strong>Conclusion: </strong>Skillful personnel and equipment to detect the anomalies in-utero and the use of modern DNA sequencing techniques to detect the possible underlying genetic defects can help us better understand the pathophysiology of various congenital disorders. Early diagnosis is crucial for optimizing management strategies and counselling parents regarding potential outcomes.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf046"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A cutaneous nodule revealing Münchmeyer's disease.","authors":"Yasmine Rkiek, Ouiame El Jouari, Mouna Rimani, Meriem Haddad, Salim Gallouj","doi":"10.1093/omcr/omaf045","DOIUrl":"10.1093/omcr/omaf045","url":null,"abstract":"<p><p>Münchmeyer's disease, also known as fibrodysplasia ossificans progressiva, is an extremely rare congenital condition affecting the musculoskeletal system, occurring in approximately 1 in 2 million people. We report the case of a 13-month-old male toddler who presented with dorsal cutaneous nodules. Examination revealed a firm, immobile nodule and congenital hallux valgus with microdactyly. Imaging studies showed ossifications of the subcutaneous tissues, and genetic testing confirmed a mutation in the ACVR1 gene, leading to the diagnosis of Münchmeyer's disease. This disabling, progressive condition is characterized by extraskeletal ossification and congenital big toe malformations. The precocity of the diagnosis in this case is noteworthy, as Münchmeyer's disease is often misdiagnosed, leading to significant delays and complications. Awareness of this rare condition is important for dermatologists to avoid missed or delayed diagnoses, as early recognition and appropriate management are crucial.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf045"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}