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Challenging diagnosis: unusual presentation of Unicentric Castleman disease-a case report.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae181
Omran Khaled Janoud, Raya Ehsan Alok, Khozama Ali Amer, Rana Mohammad Awwad, Wessam Souliman, Ghuroub Alkhayer
{"title":"Challenging diagnosis: unusual presentation of Unicentric Castleman disease-a case report.","authors":"Omran Khaled Janoud, Raya Ehsan Alok, Khozama Ali Amer, Rana Mohammad Awwad, Wessam Souliman, Ghuroub Alkhayer","doi":"10.1093/omcr/omae181","DOIUrl":"10.1093/omcr/omae181","url":null,"abstract":"<p><p>Castleman's Disease is an idiopathic rare lymphoproliferative disorder that is clinically Classified to multicentric to unicentric types. Only few cases were reported in children, with majority of them are unicentric and usually located in the mediastinum. We report a unique case of a 13-year-old boy who presented with a palpable enlarged mass in the left inguinal region without any constitutional symptoms. Surgical removal of this mass was essential to exclude worrying causes. Pathologic examination revealed proliferative changes consistent with Castleman's disease plasma cell type which is one of the rarest forms of the disease in children. To our knowledge, this case is the first reported case of Unicentric Castleman Disease (UCD) in the inguinal area. During a 12-month-period of follow-up, no additional lymph node enlargements or other symptoms were reported. In conclusion, any isolated lymph node enlargement wherever it is, especially in a child, should impose UCD as a possible differential diagnosis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae181"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An elderly patient with dementia presenting euglycaemic ketoacidosis due to oesophageal stricture-associated eating habits.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae187
Hiroaki Iwasaki, Seie Morita
{"title":"An elderly patient with dementia presenting euglycaemic ketoacidosis due to oesophageal stricture-associated eating habits.","authors":"Hiroaki Iwasaki, Seie Morita","doi":"10.1093/omcr/omae187","DOIUrl":"10.1093/omcr/omae187","url":null,"abstract":"<p><p>An 85-year-old man with dementia was referred to our department because of problematic eating habits, which made it difficult to manage his diabetes mellitus. The patient exhibited euglycaemic ketoacidosis, with a clinical course and biochemical parameters more indicative of starvation ketoacidosis rather than diabetic ketoacidosis. After correcting the acid-base imbalance with dextrose-containing fluids, he attempted to resume oral intake; however, throat noises consistent with reflux were noted during food ingestion. Imaging and pathological studies revealed a stricture with wall thickening in the mid-oesophagus attributed to non-specific chronic oesophagitis. After receiving hypercaloric fluids to calm oesophageal inflammation, an endoscopic bougienage was performed, enabling oral intake and achieving appropriate glycaemic control with oral glucose-lowering agents. This case illustrates the importance of closely monitoring eating behaviours, which is crucial for identifying comorbid organic abnormalities, without being limited by cognitive bias in clinical reasoning that problematic dietary changes are highly prevalent in dementia patients.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae187"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glandular cystitis with nephrogenic metaplasia: an unusual finding.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae184
Derqaoui Sabrine, Ibrahimi Ahmad, Jahid Ahmed, Zouaidia Fouad, Znati Kaoutar, Nouini Yassine, Bernoussi Zakia
{"title":"Glandular cystitis with nephrogenic metaplasia: an unusual finding.","authors":"Derqaoui Sabrine, Ibrahimi Ahmad, Jahid Ahmed, Zouaidia Fouad, Znati Kaoutar, Nouini Yassine, Bernoussi Zakia","doi":"10.1093/omcr/omae184","DOIUrl":"10.1093/omcr/omae184","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae184"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
(Non) twiddler syndrome in a subcutaneous implantable cardioverter-defibrillator patient-fixation first?
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae188
Maciej Bąk, Artur Oręziak, Ewa Świerżyńska-Wodarska, Maciej Sterliński, Łukasz Szumowski
{"title":"(Non) twiddler syndrome in a subcutaneous implantable cardioverter-defibrillator patient-fixation first?","authors":"Maciej Bąk, Artur Oręziak, Ewa Świerżyńska-Wodarska, Maciej Sterliński, Łukasz Szumowski","doi":"10.1093/omcr/omae188","DOIUrl":"10.1093/omcr/omae188","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae188"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous dirofilariasis.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae192
Poorvi Sharma, Nitin Gupta, Idzi Potters, Anjely Sebastian, Muralidhar Varma, Juhi Irfana Basheer, R Balakrishnan, Nancy Namrata Mahapatra, Vishwapriya M Godkhindi, Kanthilatha Pai, Anuradha Calicut Kini Rao
{"title":"Subcutaneous dirofilariasis.","authors":"Poorvi Sharma, Nitin Gupta, Idzi Potters, Anjely Sebastian, Muralidhar Varma, Juhi Irfana Basheer, R Balakrishnan, Nancy Namrata Mahapatra, Vishwapriya M Godkhindi, Kanthilatha Pai, Anuradha Calicut Kini Rao","doi":"10.1093/omcr/omae192","DOIUrl":"10.1093/omcr/omae192","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae192"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Upadacitinib in refractory Polyarteritis Nodosa: a case report.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae199
Akihiko Nakabayashi, Erika Iguchi, Dong Seop Kim, Yanakawee Siripongvutikorn, Akira Nishigaichi, Maiko Yoshimura, Hyota Takamatsu, Shiro Ohshima
{"title":"Efficacy of Upadacitinib in refractory Polyarteritis Nodosa: a case report.","authors":"Akihiko Nakabayashi, Erika Iguchi, Dong Seop Kim, Yanakawee Siripongvutikorn, Akira Nishigaichi, Maiko Yoshimura, Hyota Takamatsu, Shiro Ohshima","doi":"10.1093/omcr/omae199","DOIUrl":"10.1093/omcr/omae199","url":null,"abstract":"<p><p>Polyarteritis nodosa (PAN) is systemic vasculitis, typically treated with a combination of glucocorticoids and immunosuppressants. Changing the immunosuppressant is recommended if remission cannot be achieved with these treatments. However, there is a lack of further treatment options for patients who are unresponsive to all immunosuppressants. We report a 44-year-old Japanese man with refractory PAN who was unresponsive to various immunosuppressants (including tocilizumab). Upadacitinib treatment led to relatively rapid symptom improvement, allowing for tapering and eventual discontinuation of immunosuppressants, including prednisolone. During his 1-year follow-up, no relapse or side effects were noted. This case suggests that Janus kinase inhibitors may provide a breakthrough for patients with refractory PAN.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae199"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statin-induced immune mediated necrotising myopathy presenting with a markedly elevated cardiac troponin T in the absence of myocardial injury.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae190
David Hall, Goodness Mbonu, Zulakha Nadeem
{"title":"Statin-induced immune mediated necrotising myopathy presenting with a markedly elevated cardiac troponin T in the absence of myocardial injury.","authors":"David Hall, Goodness Mbonu, Zulakha Nadeem","doi":"10.1093/omcr/omae190","DOIUrl":"10.1093/omcr/omae190","url":null,"abstract":"<p><p>Cardiac troponin (cTn) is a sensitive test to assess for myocardial injury. However certain clinical situations can result in a raised cTn in the absence of cardiac involvement. Here we present a case of a 65-year-old woman on long term atorvastatin who presented with generalised weakness, non-specific chest pain, and a persistently elevated high sensitivity cardiac troponin T. Upon further investigation acute myocardial injury was excluded and a diagnosis of statin-induced immune mediated necrotising myopathy (IMNM) was made. The patient improved with cessation of atorvastatin and initiation of immunosuppressive therapy with mycophenolate, intravenous immunoglobulin, and steroids. The mechanism for cTn elevation in skeletal myopathies without cardiac damage and the presentation and treatment of statin-induced IMNM are reviewed. We highlight the importance that in these cases the true cause of the raised cTn is recognised to allow prompt diagnosis and treatment of the underlying myopathy.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae190"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prolonged extrapyramidal syndrome due to metoclopramide overdose: a rare case report.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae217
Abdollah Malakian, Alireza Omrani, Arshia Omrani, Yasin Ramzani, Zakaria Zakariaei
{"title":"Prolonged extrapyramidal syndrome due to metoclopramide overdose: a rare case report.","authors":"Abdollah Malakian, Alireza Omrani, Arshia Omrani, Yasin Ramzani, Zakaria Zakariaei","doi":"10.1093/omcr/omae217","DOIUrl":"10.1093/omcr/omae217","url":null,"abstract":"<p><p>Metoclopramide is a useful antiemetic drug that is widely used in medical emergencies. This drug can cause extrapyramidal side effects that are worrying. An 18-year-old girl student unintentionally consumed a large dose (60 mg) of metoclopramide, exceeding the recommended therapeutic dose, for the management of nausea and vomiting. Approximately six hours after the ingestion of the medication, she developed neck dystonia and upward deviation of the eyes. Seeing these symptoms and worrying about their child's physical condition, the parents took her to the local medical center in northern Iran. With the diagnosis of the extrapyramidal syndrome and intramuscular administration of biperiden 5 mg ampoule twice at 12-h intervals, unfortunately, the symptoms did not improve and finally he was referred to our hospital. Dystonic reactions caused by metoclopramide can be misdiagnosed and it is necessary to be monitored and treated appropriately to reduce the family's concern about its unpleasant side effects.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae217"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An incidental finding of Cor Triatriatum in an adult with left ventricular dysfunction and atrial flutter.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae189
Ruchika Meel, Keitumetsi Lucy Sothoane, Ebrahim Variava
{"title":"An incidental finding of Cor Triatriatum in an adult with left ventricular dysfunction and atrial flutter.","authors":"Ruchika Meel, Keitumetsi Lucy Sothoane, Ebrahim Variava","doi":"10.1093/omcr/omae189","DOIUrl":"10.1093/omcr/omae189","url":null,"abstract":"<p><p>The global incidence of Cor Triatriatum ranges from 0.1% to 0.4 globally. It is a rare diagnosis, with only a few cases reported in Africa. This case report outlines the first presentation of Cor Triatriatum in a 34-year-old female previously diagnosed with post-partum cardiomyopathy. The purpose of this case report was to raise awareness about the presence of congenital heart disease in adulthood as a potential cause of heart failure. Additionally, it emphasizes the importance of detailed echocardiography using advanced imaging techniques for evaluating defects and co-existing lesions.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae189"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cervical ectopic pregnancy of 11 amenorrhea weeks: clinical image.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae191
Aboubakr Benjilany, Jaouad Kouach
{"title":"Cervical ectopic pregnancy of 11 amenorrhea weeks: clinical image.","authors":"Aboubakr Benjilany, Jaouad Kouach","doi":"10.1093/omcr/omae191","DOIUrl":"10.1093/omcr/omae191","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae191"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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