Oxford Medical Case Reports最新文献

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ALCAPA: A Giant Right Coronary Artery Aneurysm.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae186
Lekhya Raavi, Nafiye Busra Celik, Pankaj Garg, John Haney
{"title":"ALCAPA: A Giant Right Coronary Artery Aneurysm.","authors":"Lekhya Raavi, Nafiye Busra Celik, Pankaj Garg, John Haney","doi":"10.1093/omcr/omae186","DOIUrl":"10.1093/omcr/omae186","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae186"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An arachnoid bleb and weeping dura-a persistent low flow CSF-leak after lumbar puncture.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae182
Amir El Rahal, Katharina Wolf, Florian Volz, Jürgen Beck
{"title":"An arachnoid bleb and weeping dura-a persistent low flow CSF-leak after lumbar puncture.","authors":"Amir El Rahal, Katharina Wolf, Florian Volz, Jürgen Beck","doi":"10.1093/omcr/omae182","DOIUrl":"10.1093/omcr/omae182","url":null,"abstract":"<p><strong>Background and importance: </strong>Post-dural puncture headache (PDPH) is a well-recognized and frequently encountered complaint of Lumbar puncture. It usually resolves spontaneously over two weeks or with an epidural blood patch. Although known for a long time, PPDH could be linked to an arachnoidal bleb as a cause of cerebrospinal fluid (CSF) leakage. We report on surgical findings and impressive findings with low-flow CSF leakage in the context of an arachnoidal bleb.</p><p><strong>Clinical presentation: </strong>We report a 42-year-old Neuroscientist with a 23-month history of positional headaches after a lumbar puncture (LP). Multiple Sclerosis was ruled out, but chronic orthostatic headache and tinnitus developed. Bed rest, caffeine tablets, IV hydration, and five high-volume epidural blood patches did not lead to improvement. However, brain fog and reduced ability to work ensued. A dynamic myelography did not reveal a CSF leak or a CSF-venous fistula, but a high-resolution T2Space Fat-saturated MRI detected an arachnoidal bleb at the alleged L3-L4 level. Microsurgical exploration identified the arachnoid bleb as a low-flow CSF leak. The video depicts Neomenbranes overlaying the dura mater appearing as a web and CSF oozing, washing a layer of blood away. CSF was leaking like a tear, and we had the impression of a weeping dura. Treatment involved bipolar shrinking, reinforcement of the dura and fibrin glue. The patient's symptoms improved slowly post-surgery.</p><p><strong>Conclusion: </strong>This case emphasises the importance of considering atypical causes of post-lumbar puncture complications, such as arachnoid blebs, and the role of surgery in identifying and treating these rare conditions.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae182"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expanding the Spectrum: a case of Giant cell arteritis encountered in familial Mediterranean fever.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae197
Rita D Moncayo, Mukhammad B Sultanov, May T H Tun, Fatemeh Mohammadrezaei, Omair A Khan, Diana Gutierrez, Sarita Konka
{"title":"Expanding the Spectrum: a case of Giant cell arteritis encountered in familial Mediterranean fever.","authors":"Rita D Moncayo, Mukhammad B Sultanov, May T H Tun, Fatemeh Mohammadrezaei, Omair A Khan, Diana Gutierrez, Sarita Konka","doi":"10.1093/omcr/omae197","DOIUrl":"10.1093/omcr/omae197","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae197"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Massive aortic root dilation in a Young male with previously undiagnosed acromegaly: a case report and review.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae185
Mahmoud Gomaa, Hassan El-Shirbiny, Osama Elshaer
{"title":"Massive aortic root dilation in a Young male with previously undiagnosed acromegaly: a case report and review.","authors":"Mahmoud Gomaa, Hassan El-Shirbiny, Osama Elshaer","doi":"10.1093/omcr/omae185","DOIUrl":"10.1093/omcr/omae185","url":null,"abstract":"<p><strong>Background: </strong>Acromegaly is an endocrine disorder characterized by excessive growth hormone (GH) production, causing abnormal bone and tissue enlargement. Typically, it presents with distinct physical changes, but some cases may lack noticeable features and still have internal abnormalities like aortic root dilation. Though rare, a family history can raise suspicion.</p><p><strong>Case presentation: </strong>This report presents a case of a 23-year-old male with no significant medical history, who presented with severe dyspnea after a chest infection. He lacked distinct physical features of genetic or endocrinal disorders, but his uncle had acromegaly. Echocardiography revealed left ventricular hypertrophy and massive aortic root dilation. Elevated insulin-like growth factor 1 (IGF-1) confirmed the diagnosis of acromegaly. The patient underwent a Bentall procedure, and his acromegaly was managed with octreotide and regular follow-ups.</p><p><strong>Conclusions: </strong>The report emphasizes the potential genetic link, and the possibility of massive aortic root dilation associated with acromegaly.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae185"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous bilateral basal ganglia hemorrhage: an unusual clinical scenario.
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-02-22 eCollection Date: 2025-02-01 DOI: 10.1093/omcr/omae183
Bhatta Sunil, Ojha Hemant, Pandit Sukriti
{"title":"Spontaneous bilateral basal ganglia hemorrhage: an unusual clinical scenario.","authors":"Bhatta Sunil, Ojha Hemant, Pandit Sukriti","doi":"10.1093/omcr/omae183","DOIUrl":"10.1093/omcr/omae183","url":null,"abstract":"<p><p>The most significant threat factor for intracerebral hemorrhage (ICH) is hypertension, which frequently results in solitary hematoma. Bilateral basal ganglia simultaneous hypertensive intracerebral hemorrhages are exceedingly rare. Few case reports of concomitant hypertensive ICH in the bilateral basal ganglia region exist in the literature. The majority of documented patients received conservative care and had dreadful prognoses. We report a case of a 43-year-old male, who presented to our emergency room with concurrent hypertensive bilateral hemorrhages within both basal ganglia. He was managed conservatively and attained a recoverable state. We would like to report this case because of the clinical rarity, paucity of published case reports, and the widespread dispute on its management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 2","pages":"omae183"},"PeriodicalIF":0.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete heart block with SARS-COV-2 infection inducing permanent pacing: a case report from a tertiary private hospital In Tanzania. 完全性心脏传导阻滞伴SARS-COV-2感染致永久性起搏1例坦桑尼亚某三级私立医院报告
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-01-18 eCollection Date: 2025-01-01 DOI: 10.1093/omcr/omae167
Pendo Ibrahim, Clement Kabakama, Venance Wilfred, Zahra Daudi, Robert Mvungi
{"title":"Complete heart block with SARS-COV-2 infection inducing permanent pacing: a case report from a tertiary private hospital In Tanzania.","authors":"Pendo Ibrahim, Clement Kabakama, Venance Wilfred, Zahra Daudi, Robert Mvungi","doi":"10.1093/omcr/omae167","DOIUrl":"10.1093/omcr/omae167","url":null,"abstract":"<p><p>There is an increased risk of cardiac complications in COVID-19 among patients with pre-existing comorbidities due to their existing pro-inflammatory status. The manifestation of complete heart block has been evidenced as transient and in no need of intervention. This case presents a previously healthy woman who was diagnosed with SARS-CoV-2 infection and complete heart block; she underwent permanent dual-chamber pacemaker implantation after successful treatment and a negative COVID-19 test. She was then discharged from the hospital with an uneventful follow-up. Persistence of complete heart block symptoms post-COVID-19 resolution and the need for permanent pacing indicate a potential association between COVID-19 and complete heart block. Healthcare workers should consider electrographic examination in the initial assessment of suspected COVID-19 cases, even among those with no pre-existing conditions. This report highlights the need for further research to explore the relationship between COVID-19 and complete heart block.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 1","pages":"omae167"},"PeriodicalIF":0.5,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of acrodysostosis type 2 with PDE4D mutation in a young female: a case report. 1例罕见的2型肢端畸形伴PDE4D突变的年轻女性:1例报告。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-01-18 eCollection Date: 2025-01-01 DOI: 10.1093/omcr/omae169
Muhammad Sheraz Hameed, Maimoona Maheen, Sauban Mansoor Sadiq, Umer Farooq, Abdur Rehman, Arham Ihtesham, Imran Khan, Shahzaib Maqbool, Javed Iqbal
{"title":"A rare case of acrodysostosis type 2 with PDE4D mutation in a young female: a case report.","authors":"Muhammad Sheraz Hameed, Maimoona Maheen, Sauban Mansoor Sadiq, Umer Farooq, Abdur Rehman, Arham Ihtesham, Imran Khan, Shahzaib Maqbool, Javed Iqbal","doi":"10.1093/omcr/omae169","DOIUrl":"10.1093/omcr/omae169","url":null,"abstract":"<p><p>Acrodysostosis (ADO) is a rare form of peripheral dysostosis characterized by skeletal malformations, growth delays, short stature, and distinctive facial features caused by in part by underdeveloped (hypoplasia) of facial bones. Skeletal dysplasia is specific and includes disproportional short stature with short extremities and brachydactyly, multiple cone-shaped epiphyses, scoliosis or kyphosis with spinal stenosis, and advanced bone maturation. Herein, we are highlighting a case that presented with clinical features such as brachydactyly, delayed milestone, growth delay, muscle weakness and nasal hypoplasia. Patient genetic testing was in line with the diagnosis of acrodysostosis. The clinic-radiological correlation was also suggestive of the rare diagnosis of ADO.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 1","pages":"omae169"},"PeriodicalIF":0.5,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tick's Nest in Auditory Canal. 耳道内的蜱窝。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-01-18 eCollection Date: 2025-01-01 DOI: 10.1093/omcr/omae160
Hann-Ziong Yueh, Shih-Chun Lu, Hung-Lun Chu, Che-Hsuan Lin
{"title":"Tick's Nest in Auditory Canal.","authors":"Hann-Ziong Yueh, Shih-Chun Lu, Hung-Lun Chu, Che-Hsuan Lin","doi":"10.1093/omcr/omae160","DOIUrl":"10.1093/omcr/omae160","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 1","pages":"omae160"},"PeriodicalIF":0.5,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parkinson's disease exacerbation following Levetiracetam administration: an unusual phenomenon. 左乙拉西坦给药后帕金森病加重:一种不寻常的现象。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-01-18 eCollection Date: 2025-01-01 DOI: 10.1093/omcr/omae174
Laila Alqahtani, Ali Alkhaibary, Farid Bouhouf
{"title":"Parkinson's disease exacerbation following Levetiracetam administration: an unusual phenomenon.","authors":"Laila Alqahtani, Ali Alkhaibary, Farid Bouhouf","doi":"10.1093/omcr/omae174","DOIUrl":"10.1093/omcr/omae174","url":null,"abstract":"<p><strong>Background: </strong>Several studies have investigated the potential beneficial and side effects of levetiracetam on Parkinson's disease (PD). We hereby report a case of PD exacerbation following Levetiracetam administration for seizure prophylaxis.</p><p><strong>Case description: </strong>A 77-year-old female, known to have PD, presented with a head injury following a fall. Brain CT showed diffuse subarachnoid hemorrhage. The patient was started on Levetiracetam for seizure prophylaxis. Four days after, the patient dropped GCS from 15 to 9. She was having progressive exacerbation of Parkinson's disease symptoms. After ruling out all possible causes of PD exacerbation, Levetiracetam was gradually weaned until it was discontinued. Consequently, the patient had rapid significant clinical improvement after discontinuation of Levetiracetam.</p><p><strong>Conclusion: </strong>The use of Levetiracetam for seizure prophylaxis in patients with PD can rarely lead to acute exacerbation of symptoms and worst outcome. Close monitoring of patients with PD is recommended when prescribing anti-epileptics.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 1","pages":"omae174"},"PeriodicalIF":0.5,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arising of autoimmune gastritis after helicobacter pylori eradication in an elderly female patient. 老年女性幽门螺杆菌根除后引起自身免疫性胃炎1例。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-01-18 eCollection Date: 2025-01-01 DOI: 10.1093/omcr/omae178
Takayoshi Kiba, Soichiro Nose
{"title":"Arising of autoimmune gastritis after <i>helicobacter pylori</i> eradication in an elderly female patient.","authors":"Takayoshi Kiba, Soichiro Nose","doi":"10.1093/omcr/omae178","DOIUrl":"10.1093/omcr/omae178","url":null,"abstract":"<p><p>Autoimmune gastritis (AIG) is a chronic condition in which the body's immune system mistakenly attacks the stomach lining, specifically targeting parietal cells that produce stomach acid and intrinsic factors. After the <i>H. pylori</i> infection was eradicated, AIG developed in an elderly woman with symptoms of the disease. 1.5 years after eradication, esophagogastroduodenoscopy revealed remnants of the oxyntic mucosa sticky adherent dense mucus and scattered minute whitish protrusions at the greater curvature of the gastric corpus. Biopsy specimens from the greater curvature site of the gastric corpus before <i>H. pylori</i> eradication revealed neutrophilic cells in the superficial mucosa of the stomach that were mildly inflammatory and infiltrating. With the removal of <i>H. pylori</i>, the number of infiltrating inflammatory neutrophilic cells in the superficial mucosa decreased, whereas that of infiltrating lymphocytes increased in the sub-superficial mucosa. This case suggests that further studies regarding the detailed time course of AIG are required.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 1","pages":"omae178"},"PeriodicalIF":0.5,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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