{"title":"Pulmonary thromboembolism-a rare presentation for Strongyloides hyperinfection in an immunocompetent patient.","authors":"Mir Wasim Ali, Soumadip Rakshit, Atreyee Sarkar, Md Karimulla Mondal, Anup Kumar Datta, Uttara Chatterjee","doi":"10.1093/omcr/omae152","DOIUrl":"10.1093/omcr/omae152","url":null,"abstract":"<p><p><i>Strongyloides stercoralis</i> is an intestinal nematode. It is widely distributed in the tropics and sub-tropics of the world. It can cause a wide array of illnesses ranging from asymptomatic autoinfection to a severe form of hyperinfection and disseminated strongyloidiasis. Here we report a case of a 73-year-old patient presenting with obstructive shock with bipedal edema without any evidence of adrenal insufficiency. An upper gastrointestinal endoscopy revealed <i>Strongyloides</i> larva in the lumen of duodenal crypts. Stool examination and broncho-alveolar lavage revealed the presence of S. stercoralis larva. Computed tomography of pulmonary angiography revealed pulmonary thromboembolism. A long segment thrombus was also noted in the right external iliac vein on color Doppler with negative screening for malignancy on computed tomography scan. This case suggests that pulmonary thromboembolism with anemia and hypoalbuminemia could be a rare presentation of a systemic illness like Strongyloides hyperinfection in an immunocompetent patient from the tropics.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae152"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter in response to case \"Variants in the SARS2 gene cause HUPRA syndrome with atypical features: two case reports and review of the literature.","authors":"Ruth Belostotsky","doi":"10.1093/omcr/omae153","DOIUrl":"10.1093/omcr/omae153","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae153"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karokh F Hama Hussein, Rawa Bapir, Dilan S Hiwa, Nali H Hama, Shorsh A Mohammed, Soran H Tahir, Lawen Jamal Mustafa, Dlshad M Faraj, Hemin S Mohammed, Sokar A Omar, Shvan H Mohammed, Fahmi H Kakamad
{"title":"Takayasu arteritis masquerading as brucellosis: a case report.","authors":"Karokh F Hama Hussein, Rawa Bapir, Dilan S Hiwa, Nali H Hama, Shorsh A Mohammed, Soran H Tahir, Lawen Jamal Mustafa, Dlshad M Faraj, Hemin S Mohammed, Sokar A Omar, Shvan H Mohammed, Fahmi H Kakamad","doi":"10.1093/omcr/omae147","DOIUrl":"10.1093/omcr/omae147","url":null,"abstract":"<p><p>This study reports a unique case of a 19-year-old male with Takayasu arteritis initially misdiagnosed as brucellosis due to persistently positive brucella serology. Despite multiple anti-brucellosis treatments, symptoms persisted until the correct diagnosis of Takayasu arteritis was made, Subsequent immunosuppressive therapy for Takayasu arteritis led to symptom improvement and normalization of serological markers. This highlights the challenge of distinguishing between these conditions and the potential for immunosuppression to impact brucella serology in such cases.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae147"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dengue pancreatitis with ketoacidosis-a rare manifestation in Endemicity.","authors":"Kalyan Kumar Das, Rajdeep Basu","doi":"10.1093/omcr/omae148","DOIUrl":"10.1093/omcr/omae148","url":null,"abstract":"<p><p>Dengue may begin as a straightforward fever episode with or without rash also it may affect some organs and cause serious symptoms. Although it is uncommon, severe abdominal discomfort has been a concerning indicator of acute pancreatitis. We report on a male patient, age 26, who first presented with fever, vomiting, and stomach pain. Later, he developed severe pancreatitis. When an acute viral infection causes pancreatitis, ketoacidosis can occur without hyperglycemia. We emphasize that in dengue patients reporting stomach pain, it is important to rule out acute pancreatitis (AP), an uncommon but serious impediment in the course of treatment.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae148"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare case of complicated typhoid fever presenting with secondary Hemophagocytic Lymphohistiocytosis.","authors":"Mir Wasim Ali, Soumadip Rakshit, Atreyee Sarkar, Md Karimulla Mondal, Anup Kumar Datta, Uttara Chatterjee","doi":"10.1093/omcr/omae151","DOIUrl":"10.1093/omcr/omae151","url":null,"abstract":"<p><p>Enteric fever is one of the important causes of tropical fever with a prevalence of 11-21 million cases worldwide annually. It encompasses both typhoid and paratyphoid fever. <i>Salmonella enterica</i> Typhi is the causative organism for typhoid fever, manifesting as an uncomplicated febrile illness to life-threatening sepsis with multiorgan dysfunction. It is complicated by neuropsychiatric manifestation (2%-40%), gastrointestinal bleeding (10%), and intestinal perforation (1%-3%). Hemophagocytic Lymphohistiocytosis (HLH) is a rare complication of typhoid fever. Herein we report the case of a 24-year-old male from North-Eastern India, presenting with spikes of fever, altered behavior, a generalized rash, haematochezia, and hemophagocytes on bone marrow examination due to hemophagocytic lymphohistiocytosis secondary to complicated typhoid fever.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omae151"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical image: emphysematous pyelonephritis.","authors":"L K Rotter, B Lee, M Golden","doi":"10.1093/omcr/omad156","DOIUrl":"10.1093/omcr/omad156","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 12","pages":"omad156"},"PeriodicalIF":0.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ameer Awashra, Fathi Milhem, Noor Nabresi, Shatha Matar
{"title":"Targetoid skin lesions in a newborn: a case of erythema multiforme.","authors":"Ameer Awashra, Fathi Milhem, Noor Nabresi, Shatha Matar","doi":"10.1093/omcr/omae145","DOIUrl":"10.1093/omcr/omae145","url":null,"abstract":"<p><p>Erythema multiforme (EM) is an immune-mediated condition that manifests as targetoid skin lesions and can be triggered by various factors, including infections and vaccinations. This case report describes a 41-day-old full-term male infant who developed widespread annular, bullseye-shaped erythematous skin lesions one week after receiving the Bacillus Calmette-Guérin (BCG) vaccination. The infant, exclusively breastfed and without a significant past medical history, presented with these lesions but no associated systemic symptoms. Physical examination revealed characteristic targetoid lesions, sparing the face, palms, soles, and mucous membranes. Laboratory tests, including a complete blood count and infection markers, were within normal ranges except for a mildly elevated C-reactive protein. The differential diagnosis ruled out other conditions and EM diagnosis is confirmed. The infant was managed conservatively with supportive care, and the lesions resolved without the need for antibiotics or any additional therapy. The patient remained stable and was discharged with instructions for monitoring and follow-up. So this case highlights the importance of distinguishing EM from other similar conditions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and urticaria.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae145"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare case of endoscopic visualization of a metallic coil in a duodenal ulcer after transcatheter arterial embolization.","authors":"Prince A Ameyaw, Ans A Jajja, Ysabel Ilagan-Ying","doi":"10.1093/omcr/omae143","DOIUrl":"10.1093/omcr/omae143","url":null,"abstract":"<p><p>Transcatheter arterial embolization is the therapy of choice for recurrent peptic ulcer bleeding refractory to standard endoscopic hemostatic techniques. It offers a minimally invasive approach with high efficacy, lower mortality, and complication rates compared to surgery. However, rare adverse events attributed to coil migration including pulmonary embolism, stroke, myocardial infarction, and bowel obstruction have been reported. We report the case of a 72-year-old female with a massive duodenal ulcer bleed refractory to endoscopic hemostatic techniques of epinephrine injection and bipolar cautery. She had a successful transcatheter arterial embolization of the culprit vessels. Repeat esophagogastroduodenoscopy for increasing vasopressor requirements and transfusion unresponsive anemia revealed the visualization of the metallic coil in the duodenal ulcer base with no active bleeding which was successfully managed conservatively through multidisciplinary consultation.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae143"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Posterior localized nodular scleritis mimicking malignancy, a case report and clinical approach.","authors":"Mehrdad Motamed Shariati, Farid Shekarchian, Aliakbar Sabermoghaddam, Mitra Karimi Amir Abadi, Nasser Shoeibi","doi":"10.1093/omcr/omae146","DOIUrl":"10.1093/omcr/omae146","url":null,"abstract":"<p><p><b>Aim</b>: To report a patient with choroidal bulging, sub-retinal fluid, and optic nerve head (ONH) swelling who was finally diagnosed with focal nodular posterior scleritis. <b>Case report</b>: A 51-year-old male patient presented to us with acute painful visual loss of his left eye (LE) from 3 days ago. The best-corrected distance visual acuity (BCDVA) was 20/20 and hand motion (HM) for the right eye (RE) and LE, respectively. Fundus examination of the LE showed ONH swelling, choroidal bulging, multiple patches of subretinal fluid accumulation, and retinal pigment epithelial (RPE) corrugations. Orbital and brain MRI showed a retrobulbar nodular mass with gadolinium enhancement at the optic nerve and sclera junction. Oncology and rheumatology work-ups were unremarkable. With the clinical diagnosis of nodular posterior scleritis oral prednisolone 50 mg/Kg was started. <b>Conclusion</b>: Posterior scleritis is an uncommon inflammatory condition that could be misdiagnosed with choroidal tumors, posterior uveitis, and orbital inflammation.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae146"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dzhem Farandzha, Kristina Stancheva, Petar Iliev, Embie Azis, Dobri Hazarbasanov
{"title":"Coronary artery microfistulae, Thebesian veins, or vessels of Wearn?","authors":"Dzhem Farandzha, Kristina Stancheva, Petar Iliev, Embie Azis, Dobri Hazarbasanov","doi":"10.1093/omcr/omae144","DOIUrl":"10.1093/omcr/omae144","url":null,"abstract":"<p><p>We present the case of a 73-year-old woman with coronary artery-left ventricular multiple microfistulae, who was admitted with symptoms and ECG suggestive of coronary artery disease. Coronary angiography revealed tortuous coronary arteries with multiple microfistulae between the left coronary artery and the left ventricle, as well as between the right coronary artery and the left ventricle. Transthoracic echocardiography (TTE) was also able to clearly demonstrate the presence of the microfistulae with their direction of blood flow towards the left ventricle. Despite traditional reliance on coronary angiography, this case advocates for the diagnostic role of TTE due to its non-invasive nature and ability to provide crucial preliminary information, even in cases with such small structures as these microfistulae. We emphasize the importance of precise, modern terminology over historical eponyms such as Thebesian veins or vessels of Wearn, aligning medical communication with contemporary diagnostic capabilities.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae144"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}