Oxford Medical Case Reports最新文献_第2页

Candida graft arteritis after kidney transplantation: two cases and literature review. 肾移植后假丝酵母移植物动脉炎2例并文献复习。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf172

Tirlangi Praveen Kumar, Attur Ravindra Prabhu, Pothumarthy Venkata Swathi Kiran, Arun Chawla, P S Priya, Brij Mohan Kumar Singh, Nitin Gupta

{"title":"Candida graft arteritis after kidney transplantation: two cases and literature review.","authors":"Tirlangi Praveen Kumar, Attur Ravindra Prabhu, Pothumarthy Venkata Swathi Kiran, Arun Chawla, P S Priya, Brij Mohan Kumar Singh, Nitin Gupta","doi":"10.1093/omcr/omaf172","DOIUrl":"10.1093/omcr/omaf172","url":null,"abstract":"Background: Candida arteritis of a kidney allograft represents a severe yet rare complication in transplant recipients. Its nonspecific presentation and diagnostic difficulties necessitate a high level of clinical suspicion and a multidisciplinary approach to management.Case presentation: We report two cases of Candida arteritis in kidney transplant recipients who presented with life-threatening bleeding from the graft anastomotic site shortly after transplantation. Histopathological examination revealed fungal invasion of the arterial walls, with periodic acid-Schiff (PAS) staining demonstrating budding yeast cells and pseudo hyphae. Both patients underwent emergency graft nephrectomy and iliac vessel repair. Antifungal therapy with intravenous fluconazole was initiated. Despite these interventions, one patient succumbed to a rebleed ten days postoperatively, while the other survived but experienced graft loss.Conclusion: This report highlights the importance of early recognition, maintenance of sterile conditions during organ transport and vigilant postoperative monitoring to minimise the occurrence of this life-threatening complication burden.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 9","pages":"omaf172"},"PeriodicalIF":0.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hermansky-Pudlak syndrome-rare type 10 with AP3D1 mutation. Hermansky-Pudlak综合征-罕见的10型AP3D1突变。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf184

Vijayakumar Balaraddi, Ketaki Nawlakhe, Shilpa K, Prathik Bandiya

引用次数: 0

Adams-Oliver syndrome: an unusual congenital disorder. 亚当斯-奥利弗综合症：一种不寻常的先天性疾病。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf176

Leen Jarjanazi, Sarah Kebbeh, Eymar Alam, Qamar Saado, Mulham Jarjanazi, Lama Alkadi, Aladdin Etr, Taoufik Ghazal Aswad, Hamdi Nawfal

{"title":"Adams-Oliver syndrome: an unusual congenital disorder.","authors":"Leen Jarjanazi, Sarah Kebbeh, Eymar Alam, Qamar Saado, Mulham Jarjanazi, Lama Alkadi, Aladdin Etr, Taoufik Ghazal Aswad, Hamdi Nawfal","doi":"10.1093/omcr/omaf176","DOIUrl":"10.1093/omcr/omaf176","url":null,"abstract":"Background: Adams-Oliver syndrome (AOS) is a rare congenital disorder characterized by scalp and limb malformations, including scalp aplasia and digital anomalies such as brachydactyly or oligodactyly. While typically inherited through either autosomal dominant or recessive patterns, sporadic cases have also been documented.Case presentation: A male neonate, born to consanguineous parents, presented with classic features of AOS including aplasia cutis congenita (ACC) and terminal transverse limb defects (TTLD). The mother reported antidepressant use during the first trimester. Prenatal ultrasound findings were suggestive of AOS, which was confirmed postnatally by a large vertex scalp defect with absent skin and bone along with bilateral brachysyndactyly. All biochemical tests were normal, with no evidence of cardiovascular or neurological abnormalities.Conclusions: This case highlights the critical importance of early prenatal diagnosis for severe AOS through meticulous sagittal plane ultrasonography to detect vertex bone ossification defects. Given the poor postnatal prognosis, early recognition is essential to improve outcomes through timely intervention.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 9","pages":"omaf176"},"PeriodicalIF":0.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salt-losing syndrome as a mimicker of the Nephroprotective effect of Gliflozins in Proteinuric nephropathies. 格列净对蛋白尿肾病肾保护作用的盐流失综合征模拟。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf163

Giulio Romano, Fiorini Nicholas, Gianluca Colussi

引用次数: 0

Paraneoplastic Dermatomyositis presenting as Supraglottitis and acute heart failure; a case report. 副肿瘤性皮肌炎表现为声门上炎和急性心力衰竭；一份病例报告。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf167

John P McCormick, Aiden Kenny, Mark Coyle, Caitlin Waters, Oisin Galvin, Emiliano Bianchini, Faisal Sharif

{"title":"Paraneoplastic Dermatomyositis presenting as Supraglottitis and acute heart failure; a case report.","authors":"John P McCormick, Aiden Kenny, Mark Coyle, Caitlin Waters, Oisin Galvin, Emiliano Bianchini, Faisal Sharif","doi":"10.1093/omcr/omaf167","DOIUrl":"10.1093/omcr/omaf167","url":null,"abstract":"Dermatomyositis is a rare autoimmune condition with a highly variable clinical presentation characterized by skin changes and skeletal myopathy. It is frequently associated with underlying malignancy. Rare manifestations including myocarditis and upper airway oedema have been described. We present an unusual case of paraneoplastic dermatomyositis which manifested as acute airway compromise and heart failure in a previously healthy 77-year-old man. The combination of symmetrical proximal myopathy, dysphagia, rash and myocarditis suggested inflammatory myositis. The clinical diagnosis was supported by positive laboratory findings including anti-TIF1 antibodies and characteristic changes on cardiac and musculoskeletal MRI. Endoscopic oesophageal biopsy demonstrated high-grade adenocarcinoma. To our knowledge this is the first reported case of acute supraglottitis as a presentation of paraneoplastic dermatomyositis. Dermatomyositis should be considered in the differential of all patients presenting with muscle weakness and rash, even if other symptoms are dominant at the time of presentation.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 9","pages":"omaf167"},"PeriodicalIF":0.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of medullary thyroid carcinoma on a toxic nodule: about an exceptional case. 甲状腺髓样癌在毒性结节上的发展：关于一个例外病例。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf178

Ali Halouache, Lahoussaine Abainou, Hajar Agouri, Mohammed Tbouda, Ismael Nakkabi

引用次数: 0

Hereditary Hemorrhagic telangiectasia: a rare familial case with delayed diagnosis despite decades of recurrent bleeding. 遗传性出血性毛细血管扩张：一个罕见的家族病例延迟诊断，尽管数十年的复发性出血。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf189

Ashutosh Vardhan Rahi, Abhishek Kumar, Jitendra Singh, Nilesh Kumar, Kailash Kumar, Anju Dinkar

{"title":"Hereditary Hemorrhagic telangiectasia: a rare familial case with delayed diagnosis despite decades of recurrent bleeding.","authors":"Ashutosh Vardhan Rahi, Abhishek Kumar, Jitendra Singh, Nilesh Kumar, Kailash Kumar, Anju Dinkar","doi":"10.1093/omcr/omaf189","DOIUrl":"10.1093/omcr/omaf189","url":null,"abstract":"Hereditary Hemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome, is a rare autosomal dominant vascular disorder characterized by mucocutaneous telangiectasias and visceral arteriovenous malformations (AVMs). We report the case of a 45-year-old male with a 20-year history of recurrent spontaneous epistaxis, chronic fatigue, and iron deficiency anemia, unresponsive to repeated nasal cauterizations. A strong family history of similar bleeding episodes in his mother and son heightened clinical suspicion. Examination revealed severe pallor without visible telangiectasias. Upper gastrointestinal endoscopy demonstrated telangiectatic lesions, while imaging excluded pulmonary and cerebral AVMs. Genetic testing confirmed HHT type 2 by detecting a pathogenic ACVRL1 gene variant. The patient was managed with intravenous iron, blood transfusions, topical nasal care, and laser therapy for refractory epistaxis. This case underscores the diagnostic challenges of HHT without classical telangiectasias and highlights the importance of early genetic testing and family screening to prevent serious complications.","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 9","pages":"omaf189"},"PeriodicalIF":0.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Disseminated fungal infection with Saprochaete capitata in acute myeloid leukemia patient: a case report from a developing country. 更正：急性髓性白血病患者弥散性头臭毛菌真菌感染：一发展中国家病例报告。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf221

引用次数: 0

Lentiform fork sign in uraemic encephalopathy: clinical image. 尿毒性脑病的慢形叉征：临床影像。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf169

Pramith Ruwanpathirana, Kaveendra Pathirage, Thamalee Palliyaguru

引用次数: 0

Enteric duplication cyst presenting as Hematochezia. 肠重复囊肿表现为便血。

IF 0.4

Oxford Medical Case Reports Pub Date : 2025-09-28 eCollection Date: 2025-09-01 DOI: 10.1093/omcr/omaf162

L K Pragathi, Vishrutha Poojari, Dhruv Gandhi, Ira Shah, Leena Patwardhan, Pradnya Bendre

引用次数: 0