{"title":"First reported case of axillary Angiolymphoid hyperplasia with eosinophilia: a rare localization and literature review.","authors":"Dyala Sayed Ahmed, Zeinab Mustafa Asmar, Moatasem Hussein Al-Janabi, Fouz Hassan","doi":"10.1093/omcr/omaf089","DOIUrl":null,"url":null,"abstract":"<p><p>Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign vasoproliferative disorder that commonly affects the scalp and periauricular region. It presents as solitary or multiple erythematous papules or nodules, typically in young to middle-aged adults. The etiology remains unclear, with trauma, infections, and hormonal influences considered possible triggers. Here, we report a rare case of ALHE in a 72-year-old male with multiple scalp nodules and a solitary lesion in the axilla, an unusual anatomical site. Histopathological examination confirmed ALHE. Surgical excision was performed, with no recurrence at six months. To our knowledge, this is the first documented case of axillary ALHE, expanding the spectrum of its clinical presentation.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf089"},"PeriodicalIF":0.5000,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205433/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omaf089","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign vasoproliferative disorder that commonly affects the scalp and periauricular region. It presents as solitary or multiple erythematous papules or nodules, typically in young to middle-aged adults. The etiology remains unclear, with trauma, infections, and hormonal influences considered possible triggers. Here, we report a rare case of ALHE in a 72-year-old male with multiple scalp nodules and a solitary lesion in the axilla, an unusual anatomical site. Histopathological examination confirmed ALHE. Surgical excision was performed, with no recurrence at six months. To our knowledge, this is the first documented case of axillary ALHE, expanding the spectrum of its clinical presentation.
期刊介绍：
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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