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Rare metastasis of renal cell carcinoma to the breast: a case report. 罕见的肾细胞癌转移至乳腺1例。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf029
Aman Saswat Sahoo, Bhuvi Singh, Monther Salman, Lilia Ragad, Rasheed Elayyan
{"title":"Rare metastasis of renal cell carcinoma to the breast: a case report.","authors":"Aman Saswat Sahoo, Bhuvi Singh, Monther Salman, Lilia Ragad, Rasheed Elayyan","doi":"10.1093/omcr/omaf029","DOIUrl":"10.1093/omcr/omaf029","url":null,"abstract":"<p><p>Renal cell carcinoma is an aggressive urological malignancy, accounting for 2%-3% of adult cancers and over 90% of renal cancers. While renal cell carcinoma commonly metastasizes to organs such as the lungs, bones, and liver, breast metastasis is rare, comprising only 0.5% to 2% of all breast neoplasms. This case report describes a 54-year-old female with a history of RCC who developed a metastatic lesion in her breast six years after radical nephrectomy. The lesion, initially detected via routine imaging, was confirmed as renal cell carcinoma through histopathology and immunohistochemistry. A wide local excision was performed, avoiding unnecessary axillary surgery. This case highlights the need for meticulous diagnostic evaluation to distinguish between primary breast carcinoma and metastatic disease, particularly in patients with a history of renal cell carcinoma. The rarity of renal cell carcinoma metastasis to the breast calls for further research to guide appropriate management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf029"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Torsion Giant ovarian cysts in a postmenopausal woman with cervical cancer. 扭转巨大卵巢囊肿绝经后妇女宫颈癌。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf054
Brahmana Askandar Tjokroprawiro, Khoirunnisa Novitasari, Renata Alya Ulhaq
{"title":"Torsion Giant ovarian cysts in a postmenopausal woman with cervical cancer.","authors":"Brahmana Askandar Tjokroprawiro, Khoirunnisa Novitasari, Renata Alya Ulhaq","doi":"10.1093/omcr/omaf054","DOIUrl":"10.1093/omcr/omaf054","url":null,"abstract":"<p><p>Ovarian torsion is a rare gynecological emergency, particularly in postmenopausal women, and is associated with significant morbidity if not promptly managed. The occurrence of torsion in giant ovarian cysts (>20 cm) is exceptionally uncommon, posing diagnostic and therapeutic challenges. A 67-year-old postmenopausal woman with stage IIIB cervical cancer presented with worsening abdominal pain and vaginal bleeding over three months. During surgery, a 30 cm giant right ovarian cyst with torsion and a smaller left dermoid cyst were identified. The patient underwent bilateral salpingo-oophorectomy, and histopathological findings confirmed a right benign serous cystadenoma with mature teratoma and struma ovary and left serous cystadenoma and dermoid cyst. Postoperatively, she received chemoradiation for cervical cancer and remained asymptomatic at one-year follow-up. This case emphasizes the need for prompt diagnosis and management of ovarian torsion in postmenopausal women, especially in complex clinical scenarios involving coexisting conditions such as cervical cancer.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf054"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fifth carpometacarpal dislocation accompanying fourth metacarpal fracture: an easily missed diagnosis. 第五掌骨脱位伴第四掌骨骨折：一个容易漏诊的病例。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf041
Marvin M T Chung
{"title":"Fifth carpometacarpal dislocation accompanying fourth metacarpal fracture: an easily missed diagnosis.","authors":"Marvin M T Chung","doi":"10.1093/omcr/omaf041","DOIUrl":"10.1093/omcr/omaf041","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf041"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Image-Vertebral artery beading in a child with Beta Thalassemia major. 临床影像-儿童β地中海贫血的椎动脉串珠。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf023
Shiji Chalipat, Vishwanath Kulkarni, Jayanth Krishna, Allan Mathew, Shailaja Mane
{"title":"Clinical Image-Vertebral artery beading in a child with Beta Thalassemia major.","authors":"Shiji Chalipat, Vishwanath Kulkarni, Jayanth Krishna, Allan Mathew, Shailaja Mane","doi":"10.1093/omcr/omaf023","DOIUrl":"10.1093/omcr/omaf023","url":null,"abstract":"<p><p>Vertebral artery beading is an uncommon, vascular complication associated with various systemic conditions. We describe the vascular imaging of a 11-year-old boy with Beta Thalassemia Major who developed acute ataxia following a splenectomy. MR angiography revealed a notable finding: symmetric, bilateral vertebral artery beading; while Digital Subtraction Angiography (DSA) was normal. This case highlights an intriguing imaging feature that mimics vasculopathy, underscoring the importance of careful interpretation in such contexts.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf023"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invasive streptococcus dysgalactiae endocarditis with extensive multiorgan involvement. 侵袭性无乳链球菌性心内膜炎广泛累及多器官。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf053
I-Chun Chen, Daniel Rhyner, Nina Durisch
{"title":"Invasive <i>streptococcus dysgalactiae</i> endocarditis with extensive multiorgan involvement.","authors":"I-Chun Chen, Daniel Rhyner, Nina Durisch","doi":"10.1093/omcr/omaf053","DOIUrl":"10.1093/omcr/omaf053","url":null,"abstract":"<p><p>We report a rare, severe case of invasive <i>Streptococcus dysgalactiae</i> endocarditis with multiorgan involvement in a middle-aged man with few comorbidities. The patient presented with fever, malaise, and back pain, and was diagnosed with infective endocarditis (IE) involving the mitral valve, septic arthritis, renal and splenic infarctions, septic cerebral emboli, endophthalmitis, and multiple epidural and intramuscular abscesses. Treatment involved prolonged antibiotics and surgical drainage of an elbow abscess. After a prolonged hospital stay and intensive rehabilitation, the patient achieved a favourable outcome.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf053"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal clear cell sarcoma, AKA malignant gastrointestinal Neuroectodermal tumor: an uncommon entity in a young patient presenting with Anemia, Intraabdominal mass and subsequent liver metastasis. 胃肠道透明细胞肉瘤，又名恶性胃肠道神经外胚层肿瘤：一种罕见的实体，在年轻患者中表现为贫血，腹内肿块和随后的肝转移。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf028
Sara Salehiazar, Sava Grujic
{"title":"Gastrointestinal clear cell sarcoma, AKA malignant gastrointestinal Neuroectodermal tumor: an uncommon entity in a young patient presenting with Anemia, Intraabdominal mass and subsequent liver metastasis.","authors":"Sara Salehiazar, Sava Grujic","doi":"10.1093/omcr/omaf028","DOIUrl":"10.1093/omcr/omaf028","url":null,"abstract":"<p><p>Gastrointestinal clear cell sarcoma is a rare tumor with neuroectodermal differentiation that affects the gastrointestinal tract and involves gene fusion translocations of EWSR1. These tumors predominantly occur in young adults and often display aggressive behavior, with metastases to lymph nodes and the liver. Histologically, the tumor comprises uniform round cells with round nuclei and pale eosinophilic or clear cytoplasm. It exhibits variable mitotic activity and demonstrates positive immunohistochemical staining for S100 and SOX10, while specific melanocytic markers are negative. Currently, no tailored chemotherapy regimen has been identified for this entity. Due to the limited number of reported cases, effective management strategies remain unclear. Here, we present the case of a young adult patient diagnosed with CCS/GNET using immunohistochemistry. The diagnosis was confirmed by next-generation sequencing (NGS), which detected the characteristic EWSR1-ATF1 gene fusion, and liver metastases were identified during follow-up.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf028"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Twist of Fate: Life-Threatening SMA Thrombosis Caused by Mesenteric Torsion Post-Roux-en-Y Weight Loss. 命运的扭曲：roux -en- y减肥后肠系膜扭转引起的危及生命的SMA血栓形成。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf025
Mohamed Ayman Ebrahim, Shahin Isha, Andranik Bedross, Parth Patel, Ashok Kumar
{"title":"Twist of Fate: Life-Threatening SMA Thrombosis Caused by Mesenteric Torsion Post-Roux-en-Y Weight Loss.","authors":"Mohamed Ayman Ebrahim, Shahin Isha, Andranik Bedross, Parth Patel, Ashok Kumar","doi":"10.1093/omcr/omaf025","DOIUrl":"10.1093/omcr/omaf025","url":null,"abstract":"<p><p>Superior mesenteric artery (SMA) thrombosis is rare yet critical illness that can result in lethal bowel ischemia and infarction. This report details a case of SMA thrombosis with associated superior mesenteric vein (SMV) narrowing, secondary to mesenteric torsion in a 26-year-old female with history of Roux-en-Y gastric bypass surgery. The patient's presenting symptoms were severe epigastric pain, vomiting, and significant anemia. Imaging confirmed SMA thrombosis with early signs of bowel ischemia. Interventional radiology promptly performed an SMA angiogram and initiated thrombolysis with a tenecteplase infusion, which led to near-complete resolution of the thrombus. This case draws attention to the necessity for early diagnosis and swift management of SMA thrombosis, particularly in post-surgical patients with altered gastrointestinal anatomy. The resolution of this case demonstrates the value of a collaborative care, combining interventional radiology and general surgery to prevent bowel ischemia.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf025"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effective non-surgical management of spinal cord compression from extra-medullary hematopoiesis with radiotherapy in thalassemia intermedia: a case report. 髓外造血放射治疗中地中海贫血脊髓压迫的有效非手术治疗：1例报告。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf039
Zoheir Reihanian, Nooshin Zaresharifi, Behrad Eftekhari, Anita Khalili, Ainaz Sourati, Fatemeh Nejatifar
{"title":"Effective non-surgical management of spinal cord compression from extra-medullary hematopoiesis with radiotherapy in thalassemia intermedia: a case report.","authors":"Zoheir Reihanian, Nooshin Zaresharifi, Behrad Eftekhari, Anita Khalili, Ainaz Sourati, Fatemeh Nejatifar","doi":"10.1093/omcr/omaf039","DOIUrl":"10.1093/omcr/omaf039","url":null,"abstract":"<p><p>Spinal cord compression (SCC) secondary to extramedullary hematopoiesis (EMH) represents a rare but critical manifestation in patients with hematologic conditions, including β-thalassemia intermedia (β-TI). While there is no standard guideline due to the rarity of EMH-induced SCC, this case report documents successful management with radiotherapy while avoiding high-risk surgical intervention. The patient was a 17-year-old male with β-TI who developed debilitating SCC attributable to a paraspinal EMH mass. Due to concerns regarding surgical morbidity, a 26Gy 13-session course of radiation was administered alongside adjunctive blood transfusions, Hydroxyurea, and Glucocorticoids. Marked improvement and subsequent resolution of neurological deficits occurred rapidly following treatment, with sustained regression of the EMH mass over 18 months of follow-up. The case demonstrates that radiotherapy can be an effective primary treatment for EMH-induced SCC in β-TI, emphasizing its safety and efficacy when immediate and significant clinical response is required.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf039"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical case report: understanding Kienböck's disease. 临床病例报告：了解Kienböck病。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf050
Ricardo A Caravantes, Daniela Saenz, Favio Reyna
{"title":"Clinical case report: understanding Kienböck's disease.","authors":"Ricardo A Caravantes, Daniela Saenz, Favio Reyna","doi":"10.1093/omcr/omaf050","DOIUrl":"10.1093/omcr/omaf050","url":null,"abstract":"<p><p>Kienböck's disease, or lunate osteonecrosis, is a rare condition characterized by avascular necrosis of the lunate bone in the wrist. The pathophysiology involves disruption of blood supply to the lunate, leading to bone ischemia and subsequent collapse. This case report presents the clinical course and diagnostic challenges of a patient diagnosed with Kienböck's disease. This case highlights the challenges on the importance of early diagnosis and appropriate treatment to mitigate progression and improve patient outcomes.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf050"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metronidazole's hidden impact: decoding cerebellar clues on MRI through a case report. 甲硝唑的隐性影响：通过病例报告解读MRI小脑线索。
IF 0.5
Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI: 10.1093/omcr/omaf024
Basma Beqqali, Joud Boutaleb, Basma Dghoughi, Lina Lasri, I Z I Zineb, Mohamed Bouchentouf, Tarik Salaheddine, Rachida Saouab, Meryem Edderai, Jamal Elfenni
{"title":"Metronidazole's hidden impact: decoding cerebellar clues on MRI through a case report.","authors":"Basma Beqqali, Joud Boutaleb, Basma Dghoughi, Lina Lasri, I Z I Zineb, Mohamed Bouchentouf, Tarik Salaheddine, Rachida Saouab, Meryem Edderai, Jamal Elfenni","doi":"10.1093/omcr/omaf024","DOIUrl":"10.1093/omcr/omaf024","url":null,"abstract":"<p><p>A 70-year-old patient with a history of skull base osteomyelitis experienced slurred speech, dizziness, and coordination issues. He had been treated with both intravenous and oral metronidazole. Brain MRI revealed symmetrical areas of hyperintensity in the bilateral dentate nuclei, tectum, and splenium of the corpus callosum. These abnormalities nearly completely disappeared a few days after stopping the medication. Metronidazole, frequently used as an antiparasitic and antibacterial drug, can lead to neurotoxicity, particularly when used for extended periods. Symptoms generally improve after the drug is discontinued. MRI is vital for diagnosis and follow-up, as it detects specific changes in brain regions due to axonal swelling and increased water content.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf024"},"PeriodicalIF":0.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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