Anna Pan, Shuang Xu, Liang Hong, Wenwei Zhu, Yu Zhou, Xiaoyang Wang
{"title":"Hepatic epithelioid Hemangioendothelioma presenting synchronously with hepatocellular carcinoma-a case report.","authors":"Anna Pan, Shuang Xu, Liang Hong, Wenwei Zhu, Yu Zhou, Xiaoyang Wang","doi":"10.1093/omcr/omae140","DOIUrl":"10.1093/omcr/omae140","url":null,"abstract":"<p><strong>Backgrounds: </strong>Primary hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplasm of vascular origin with varying biologic behavior, making it challenging to diagnose.</p><p><strong>Case presentation: </strong>We present a case of synchronous hepatocellular carcinoma (HCC) and HEHE in a 43-year-old Chinese male patient. Multiple hypoechoic liver lesions were depicted, but no specific imaging findings were detected on enhanced computed tomography (CT) or contrast-enhanced magnetic resonance imaging (MRI). The patient then underwent [<sup>18</sup>F]-FDG PET/CT, [<sup>11</sup>C]-acetate PET/CT, and [<sup>68</sup>Ga]Ga-FAPI-04 PET/CT. The HEHE lesions demonstrated no uptake on both <sup>18</sup>F-FDG and <sup>11</sup>C-acetate PET/CT imaging, but presented a clear visualization in [<sup>68</sup>Ga]Ga-FAPI-04 PET/CT. The largest lesion located in segment VII was finally diagnosed as HCC, while the other smaller ones were diagnosed as HEHE, which was confirmed by immunohistochemical staining for CD31. To the best of our knowledge, only 2 cases have been reported in the worldwide literature, and the first case undertook both <sup>11</sup>C-acetate and [<sup>68</sup>Ga]Ga-FAPI-04 PET/CT instead of <sup>18</sup>F-FDG PET/CT.</p><p><strong>Conclusion: </strong>In this report, we show that HCC and HEHE may occur synchronously, and HEHE should be considered when liver lesions are detected. [<sup>68</sup>Ga]Ga-FAPI-04 PET/CT has great potential in the detection, staging and therapy selection of HEHE.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae140"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pierre Delzongle, Marie Binvignat, Christelle Nguyen
{"title":"Hand rheumatoid nodules.","authors":"Pierre Delzongle, Marie Binvignat, Christelle Nguyen","doi":"10.1093/omcr/omae142","DOIUrl":"https://doi.org/10.1093/omcr/omae142","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae142"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevention of cardiac tamponade by left intercostal Pericardiotomy for massive recurrent pericardial effusion: a case report.","authors":"Tomohiro Nakajima, Kei Mukawa, Hidemichi Kouzu, Ayaka Kamada, Nobuyoshi Kawaharada","doi":"10.1093/omcr/omae139","DOIUrl":"10.1093/omcr/omae139","url":null,"abstract":"<p><p>This case involved an 89-year-old woman with a history of left nephrectomy for left renal cell carcinoma at the age of 87 years. She had been gradually accumulating pericardial effusion for the past 4 years. She presented with signs of tachycardia and hypotension suggestive of cardiac tamponade due to pericardial effusion, and pericardiocentesis was performed below the xiphoid process in the cardiology department. Serous fluid was aspirated, and malignancy was ruled out by various tests. The patient subsequently developed recurrent pericardial effusion and was admitted to the hospital. Cardiovascular surgery was performed for pericardial drainage. A left intercostal incision was made for pericardiotomy and drainage of the pericardial effusion, allowing it to accumulate in the left pleural cavity in case of future accumulation. Pathological examination of the pericardium revealed no specific findings, and no cancer cells were present in the pericardial fluid. Prednisolone therapy was initiated for idiopathic pericarditis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae139"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond the expected: left ventricular myocardial hydatid cyst a case report.","authors":"Safae Lanjeri, Kaoutar Imrani, Oumaima Mesbah, Nabil Mouatassim Billah, Ittimade Nassar","doi":"10.1093/omcr/omae141","DOIUrl":"10.1093/omcr/omae141","url":null,"abstract":"<p><p>Hydatid disease is an infection caused by the larval form of Echinococcus. It is a zoonosis primarily affecting the lungs and liver. While pulmonary involvement is most common, the cysts can develop in various extrapulmonary sites within the thorax, such as the pleural cavity, fissures, mediastinum, heart, vascular structures, chest wall, and diaphragm. However, intracardiac localization of hydatid cyst is very rare and it is found in less than 2% of cases. Cardiac involvement can be caused by systemic or pulmonary circulation, or by direct spread from adjacent structures. Imaging techniques, particularly MRI, play a crucial role not only in diagnosing hydatid cysts, but also in assessing their extension and identifying complications. We report a case of a 13-year-old girl, with a left ventricular myocardial hydatid cyst.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae141"},"PeriodicalIF":0.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patent ductus arteriosus with pulmonary endarteritis leading to pulmonary infarction in a 9-year-old boy: a case report.","authors":"Amshu Shakya, Urmila Shakya, Subash Chandra Shah, Vidhata Bhandari Kc, Devaki Khadka, Urusha Ghulu","doi":"10.1093/omcr/omae132","DOIUrl":"10.1093/omcr/omae132","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary endarteritis secondary to Patent ductus arteriosus (PDA) can present even in silent PDAs. Pulmonary endarteritis is treated with prolonged duration of antibiotics followed by PDA closure. It can also cause septic pulmonary emboli requiring critical care if multi-organ dysfunction ensues.</p><p><strong>Case presentation: </strong>A 9-year-old boy had high grade fever for one week and few nonspecific complaints. Echocardiogram showed PDA with infective endarteritis. Child was admitted with IV antibiotics. CECT chest done for resurgence of fever and need for increased oxygen demand showed multiple septic pulmonary emboli with pulmonary infarction. Surgical closure of PDA prevented further clinical deterioration.</p><p><strong>Conclusion: </strong>This case highlights the poor medical scenario of rural communities of Nepal. Such life- threatening complication can be prevented by timely recognition of the condition which is only possible by implementation of standard, accessible and affordable health care system across the country.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae132"},"PeriodicalIF":0.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sdrah Diab, Moatasem Hussein Al-Janabi, Ibrahim Diab, Fouz Hassan
{"title":"Rupioid psoriasis, a unique presentation treated with Ustekinumab.","authors":"Sdrah Diab, Moatasem Hussein Al-Janabi, Ibrahim Diab, Fouz Hassan","doi":"10.1093/omcr/omae138","DOIUrl":"10.1093/omcr/omae138","url":null,"abstract":"<p><p>Rupioid psoriasis is a rare subtype of psoriasis characterized by distinctive lesions resembling oyster shells, known as rupioid lesions. This subtype is particularly uncommon in the pediatric population and is often associated with poor treatment compliance. Ustekinumab, an IgG monoclonal antibody, targets IL-12 and IL-23, reducing the release of proinflammatory cytokines TNFα, IL-2, and IL-17α, which play vital roles in psoriasis pathophysiology. Approved for pediatric patients aged six years and older, ustekinumab provides a therapeutic option for moderate to severe psoriasis. We present the case of a 10-year-old girl diagnosed with psoriasis vulgaris at age two. She presented with rupioid lesions following a urinary tract infection that had been treated with oral cefixime (200 mg). After conducting appropriate tests, ustekinumab (45 mg subcutaneously) was administered, leading to significant improvements in the thickness of the lesions and overall appearance. This case demonstrates ustekinumab's efficacy in treating this challenging form of psoriasis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae138"},"PeriodicalIF":0.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikolay Dimov, Tahsin Sultana, Aishah Dafeeah, Hafsa Choudhury, Dimitar Nikolov
{"title":"Intramuscular heroin-induced severe rhabdomyolysis and acute kidney injury-a case report.","authors":"Nikolay Dimov, Tahsin Sultana, Aishah Dafeeah, Hafsa Choudhury, Dimitar Nikolov","doi":"10.1093/omcr/omae134","DOIUrl":"10.1093/omcr/omae134","url":null,"abstract":"<p><p>Rhabdomyolysis (RM) is characterised by the breakdown of skeletal muscle tissue, releasing toxic intracellular components into circulation. It presents with dark urine, muscle weakness, myalgia, and elevated creatine phosphokinase levels (CPK). Drug-induced RM is aetiologically significant. This case report describes a 25-year-old male who developed severe RM and Acute Kidney Injury (AKI) after intramuscular (IM) heroin administration as a first time user. IM heroin use can induce higher CPK levels due to direct myocyte toxicity and mechanical trauma. The highly vascularised gluteal muscles with type 1 fibres at the injection site likely exacerbated the severity. Additional factors included lower mitochondrial density in males and alcohol exposure. Despite aggressive fluid resuscitation, renal replacement therapy (RRT) was required, and the patient responded well to haemodialysis. This case highlights AKI as a severe complication of IM heroin use, underscoring the need for further research into drug-induced RM.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae134"},"PeriodicalIF":0.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amal Babi, Baraa Shebli, Mike Ghabally, Hussein Alkanj
{"title":"Bizarre intravascular leiomyoma with intracardiac extension starting in the ovarian vein: a case report from Syria.","authors":"Amal Babi, Baraa Shebli, Mike Ghabally, Hussein Alkanj","doi":"10.1093/omcr/omae131","DOIUrl":"10.1093/omcr/omae131","url":null,"abstract":"<p><p>Intravascular leiomyoma (IVL) with intracardiac extension (ICE) represents an exceedingly rare diagnosis of a cardiac mass. We present the case of a 42-year-old woman with recurrent syncopal episodes. Cardiac investigations revealed an extensive, mobile mass stretching from the inferior vena cava (IVC) through the right heart to the bifurcation of the pulmonary artery. Emergent surgery was conducted to excise the mass. Post-operative assessment indicated a potential malignancy in the adnexa. A subsequent surgery to resect the uterus with the adnexa, the primary origin of the mass, confirmed the diagnosis of IVL with ICE. The initial diagnostic ambiguity and the urgent pulmonary artery involvement necessitated a two-step surgical approach. Despite the propensity for recurrence, a 5-year follow-up remained unremarkable. This case underscores the importance of considering IVL with ICE in the differential diagnosis, which can expedite both diagnosis and treatment.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae131"},"PeriodicalIF":0.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First documented case of Smith-Lemli-Opitz syndrome in Syria: clinical presentation, diagnosis, and experimental management with simvastatin.","authors":"Alwa Hussien Aladia, Samar Hamdan, Ahmad Alkheder","doi":"10.1093/omcr/omae129","DOIUrl":"10.1093/omcr/omae129","url":null,"abstract":"<p><p>Smith-Lemli-Opitz syndrome (SLOS) is a rare genetic disorder that affects cholesterol synthesis and causes various physical and mental abnormalities. The case is a 25-day-old male infant who presented with multiple congenital anomalies, such as microcephaly, facial dysmorphism, syndactyly, hypospadias, and other organ malformations. He also had severe vomiting, feeding difficulty, irritability, dehydration, and hyponatremia. Laboratory tests showed low serum cholesterol, in addition to genetic tests, confirming the diagnosis of SLOS. The infant was treated with simvastatin, which improved his irritability and was well tolerated. The paper discusses the clinical features, diagnosis, and management of SLOS, and highlights the importance of early recognition and intervention for this rare case. It is also considered the first documented case in Syria.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae129"},"PeriodicalIF":0.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph Aladeen, Pranav Wadhawan, Reshub Pendyala, Bikram Bajwa, Rajinder P Bajwa
{"title":"Transfusion related babesiosis in a non-endemic region (Western New York).","authors":"Joseph Aladeen, Pranav Wadhawan, Reshub Pendyala, Bikram Bajwa, Rajinder P Bajwa","doi":"10.1093/omcr/omae133","DOIUrl":"10.1093/omcr/omae133","url":null,"abstract":"<p><p>Babesiosis, an emerging tick-borne zoonosis caused by parasites of the genus Babesia, is typically transmitted via the black-legged tick. Occasionally, <i>Babesia</i> can also be transmitted through red blood cell transfusion. In this report, we present a case of babesiosis resulting from a red blood cell transfusion in an area where the pathogen is not endemic. The patient presented with a high-grade fever and hemolytic anemia. This case underscores the critical importance of recognizing Babesia as a cause of hemolysis and emphasizes the necessity of implementing universal screening of blood products for Babesia. Enhanced vigilance in blood safety protocols is imperative to prevent transfusion-associated babesiosis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2024 11","pages":"omae133"},"PeriodicalIF":0.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}