{"title":"朗格汉斯细胞组织细胞增多症伪装成地衣样疹。","authors":"Ashjan Alheggi","doi":"10.1093/omcr/omaf106","DOIUrl":null,"url":null,"abstract":"<p><p>Langerhans cell histiocytosis (LCH) is an inflammatory clonal proliferative neoplasm of immature myeloid precursor cells. These cells can accumulate in various tissues including skin, leading to tissue damage, and in some cases organ dysfunction. Herein, a report of a 1-year-old girl who presented with multiple lichenoid pinkish to purplish flat-topped papules, some of them were crusted and linear over the trunk mimicking lichen planus. The histopathologic and immunohistochemical staining confirmed the diagnosis of LCH. Awareness about this rare entity is important for early detection, timely intervention, and effective management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 7","pages":"omaf106"},"PeriodicalIF":0.4000,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296336/pdf/","citationCount":"0","resultStr":"{\"title\":\"Langerhans cell histiocytosis disguised as lichenoid eruption.\",\"authors\":\"Ashjan Alheggi\",\"doi\":\"10.1093/omcr/omaf106\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Langerhans cell histiocytosis (LCH) is an inflammatory clonal proliferative neoplasm of immature myeloid precursor cells. These cells can accumulate in various tissues including skin, leading to tissue damage, and in some cases organ dysfunction. Herein, a report of a 1-year-old girl who presented with multiple lichenoid pinkish to purplish flat-topped papules, some of them were crusted and linear over the trunk mimicking lichen planus. The histopathologic and immunohistochemical staining confirmed the diagnosis of LCH. Awareness about this rare entity is important for early detection, timely intervention, and effective management.</p>\",\"PeriodicalId\":45318,\"journal\":{\"name\":\"Oxford Medical Case Reports\",\"volume\":\"2025 7\",\"pages\":\"omaf106\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-07-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296336/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oxford Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/omcr/omaf106\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omaf106","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Langerhans cell histiocytosis disguised as lichenoid eruption.
Langerhans cell histiocytosis (LCH) is an inflammatory clonal proliferative neoplasm of immature myeloid precursor cells. These cells can accumulate in various tissues including skin, leading to tissue damage, and in some cases organ dysfunction. Herein, a report of a 1-year-old girl who presented with multiple lichenoid pinkish to purplish flat-topped papules, some of them were crusted and linear over the trunk mimicking lichen planus. The histopathologic and immunohistochemical staining confirmed the diagnosis of LCH. Awareness about this rare entity is important for early detection, timely intervention, and effective management.
期刊介绍：
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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