Hassan Moutei, Ahmed Bennis, Fouad Chraibi, Meriem Abdellaoui, Idriss Benatiya
{"title":"Unilateral macular Coloboma: a rare finding.","authors":"Hassan Moutei, Ahmed Bennis, Fouad Chraibi, Meriem Abdellaoui, Idriss Benatiya","doi":"10.1093/omcr/omaf084","DOIUrl":"10.1093/omcr/omaf084","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf084"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Badreddine Belayachi, Hamza Azal, Hicham Fenane, Yassine Msougar
{"title":"Managing pulmonary cystic Hygroma in adults: diagnostic and therapeutic considerations.","authors":"Badreddine Belayachi, Hamza Azal, Hicham Fenane, Yassine Msougar","doi":"10.1093/omcr/omaf074","DOIUrl":"10.1093/omcr/omaf074","url":null,"abstract":"<p><p>Cystic hygroma is a rare congenital anomaly typically observed in newborns, with cases in adults being exceptionally rare. In adults, these lesions often remain asymptomatic and present unique challenges owing to the absence of established treatment protocols. This report describes a 23-year-old male with a large pulmonary cystic hygroma manifesting as progressive chest discomfort, breathing difficulties, and systemic symptoms. Diagnostic imaging revealed an extensive cystic structure within the mediastinal-pulmonary region, which was managed surgically via cystotomy. Histopathological analysis confirmed the diagnosis, and the patient experienced a complete recovery with no recurrence during follow-up. This case highlights the need for standardized guidelines in the management of pulmonary cystic hygromas and emphasizes the importance of including cystic hygroma in the differential diagnosis of pulmonary masses in adults. Further studies are essential to optimize therapeutic approaches and enhance outcomes for adult patients with this rare condition.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf074"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atypical anti-glomerular basement membrane disease: two case reports.","authors":"Zaineb Kaouiri, Nada El Kadiri, Loubna Benamar, Tarik Bouattar, Lamyaa Rouas, Naima Ouzeddoun","doi":"10.1093/omcr/omaf073","DOIUrl":"10.1093/omcr/omaf073","url":null,"abstract":"<p><p>Atypical Anti-Glomerular Basement Membrane (anti-GBM) Disease, a variant of the rare autoimmune disorder Goodpasture's disease, presents unique challenges in diagnosis and management. This article presents two cases of atypical anti-GBM disease characterized by negative serological tests for anti-GBM antibodies, minimal renal impact on kidney biopsy, and absence of pulmonary involvement. These cases underscore the evolving spectrum of renal anti-GBM-related conditions and the need for a nuanced approach to diagnosis and treatment. Treatment with high-dose steroids resulted in favorable outcomes in both cases, highlighting the importance of individualized management strategies, especially given the absence of standardized recommendations for this uncommon presentation. Further research is warranted to elucidate the pathophysiology and optimal management of atypical anti-GBM disease.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf073"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rahul K Chattopadhyay, Thin K P Naing, Vassilios S Vassiliou, Gareth D Matthews
{"title":"Educational case: a 46-year-old woman with palpitations and shortness of breath.","authors":"Rahul K Chattopadhyay, Thin K P Naing, Vassilios S Vassiliou, Gareth D Matthews","doi":"10.1093/omcr/omae137","DOIUrl":"10.1093/omcr/omae137","url":null,"abstract":"<p><p>In this educational case report, the journey of a woman with atrial fibrillation is discussed, to highlight contemporary management issues in atrial fibrillation. Issues discussed include decisions on anticoagulation, rate and rhythm control, the management of refractory high rates, and the genetic basis of atrial fibrillation.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omae137"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harun Iskandar, Yusuf Haz Condeng, Nur Ahmad Tabri, Dewi Setiawati, Diana Muchsin
{"title":"Erythema Induratum as a rare manifestation of cutaneous tuberculosis in a young woman: a case report.","authors":"Harun Iskandar, Yusuf Haz Condeng, Nur Ahmad Tabri, Dewi Setiawati, Diana Muchsin","doi":"10.1093/omcr/omaf058","DOIUrl":"10.1093/omcr/omaf058","url":null,"abstract":"<p><p>Cutaneous tuberculosis (TB) is a rare form of extrapulmonary TB, often leading to diagnostic challenges due to its varied clinical presentation. Erythema induratum of Bazin (EIB), a type of lobular panniculitis, is a recognized manifestation of cutaneous TB. This report describes a 19-year-old woman who developed EIB, presenting with recurrent fever, night sweats, weight loss, and hyperpigmented nodular lesions on both lower extremities. Laboratory tests showed an elevated erythrocyte sedimentation rate and a positive tuberculin skin test, while histopathology confirmed lobular panniculitis. Pulmonary TB was excluded based on negative molecular testing and normal chest imaging. The patient was diagnosed with cutaneous TB and treated with WHO-recommended first-line anti-TB therapy, leading to significant clinical improvement. This case underscores the importance of early recognition and timely treatment of cutaneous TB to prevent complications and ensure optimal outcomes.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf058"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Basma Beqqali, Ola Messaoud, Basma Dghoughi, Joud Boutaleb, Oumaima Mesbah, Omar El Aoufir, Laila Jroundi, Zaynab Iraqi Houssaini
{"title":"Hidden danger: silicosis in a dental technician-an overlooked occupational risk.","authors":"Basma Beqqali, Ola Messaoud, Basma Dghoughi, Joud Boutaleb, Oumaima Mesbah, Omar El Aoufir, Laila Jroundi, Zaynab Iraqi Houssaini","doi":"10.1093/omcr/omaf078","DOIUrl":"10.1093/omcr/omaf078","url":null,"abstract":"<p><p>Silicosis is a chronic lung disease caused by prolonged inhalation of crystalline silica particles, frequently encountered in professionals exposed to silica dust. We report the case of a 54-year-old dental technician presenting with progressive dyspnea, where the diagnosis of silicosis was confirmed based on occupational history and characteristic radiological findings. A differential diagnosis with sarcoidosis was initially considered. This case highlights the importance of early recognition of occupational lung diseases and emphasizes the need for preventive measures to limit silica exposure.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf078"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Expanding the Spectrum: a case of Giant cell arteritis encountered in familial Mediterranean fever.","authors":"","doi":"10.1093/omcr/omaf098","DOIUrl":"https://doi.org/10.1093/omcr/omaf098","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/omcr/omae197.].</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf098"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Diaz Q, Marcos Orellana, Andrea Argueta, Pedro Chajon
{"title":"Neonatal meconium aspiration syndrome with transient Hyperreactive airways and socioeconomic challenges: a case report.","authors":"Carlos Diaz Q, Marcos Orellana, Andrea Argueta, Pedro Chajon","doi":"10.1093/omcr/omaf067","DOIUrl":"10.1093/omcr/omaf067","url":null,"abstract":"<p><p>This report presents a unique case of Meconium Aspiration Syndrome (MAS) in a neonate who developed transient hyperreactive airways syndrome (THAS), a rare complication marked by episodic bronchospasm and wheezing after MAS resolution. The patient, initially born in a private hospital in Guatemala and transferred to a community hospital due to financial constraints, improved with CPAP therapy but required bronchodilators for intermittent respiratory exacerbations. This case highlights the diverse manifestations of MAS and the need for careful monitoring of potential complications, particularly in resource-limited settings.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf067"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bianca Frigo Pires, Graziele Ines Silva Lopo, Anaí Ramoa Siqueira, Luiza Resende Felisberto, Rafaella Simão Martini, Ana Beatriz Valim Alves, Amanda Carolina Rodrigues Silva, Flávia Xavier Lima Carvalho, Aline Pirola Aliseda, Mariane Martinhon Martins, Carla Kreuzberg Salgado, Salum Bueno da Silveira Junior, Camila Garcia Ferrari Jacob
{"title":"Rare presentation of dandy-walker variant syndrome associated with leigh syndrome: a promising therapeutic approach for prognosis in children related in a case report.","authors":"Bianca Frigo Pires, Graziele Ines Silva Lopo, Anaí Ramoa Siqueira, Luiza Resende Felisberto, Rafaella Simão Martini, Ana Beatriz Valim Alves, Amanda Carolina Rodrigues Silva, Flávia Xavier Lima Carvalho, Aline Pirola Aliseda, Mariane Martinhon Martins, Carla Kreuzberg Salgado, Salum Bueno da Silveira Junior, Camila Garcia Ferrari Jacob","doi":"10.1093/omcr/omaf061","DOIUrl":"10.1093/omcr/omaf061","url":null,"abstract":"<p><strong>Introduction: </strong>Dandy-Walker syndrome (D-WS) is a rare congenital brain anomaly that primarily impacts the fourth ventricle and cerebellum. Its variant is even rarer and includes cerebellar dysgenesis, with possible posterior fossa enlargement and variable cerebellar vermis hypoplasia.</p><p><strong>Case report: </strong>We present the case of a patient diagnosed late with the Dandy-Walker Syndrome variant, associated with Leigh Syndrome, at a tertiary hospital. The patient received an optimized, multidisciplinary treatment approach to improve prognosis.</p><p><strong>Discussion: </strong>Early intervention in pediatric neurodegenerative diseases through a multidisciplinary team that includes medical, speech therapy, and physiotherapy support is crucial for a better prognosis in these cases.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 6","pages":"omaf061"},"PeriodicalIF":0.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}