Bilateral adrenal infarction in a patient with essential thrombocythemia: a case report and brief literature review.

IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL

Oxford Medical Case Reports Pub Date : 2025-08-11 eCollection Date: 2025-08-01 DOI:10.1093/omcr/omaf129

Yuko Fujishima, Yuji Hataya, Kanta Fujimoto, Toshio Iwakura, Naoki Matsuoka

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Abstract

Adrenal infarction (AI) is rare condition caused by inadequate blood supply to the adrenal glands, with few reports of its association with essential thrombocythemia (ET). Here, we report a case of bilateral AI as an initial thrombotic complication in a patient with ET. A 69-year-old man presented with right abdominal pain. Abdominal computed tomography (CT) showed diffuse enlargement and poor enhancement of bilateral adrenal glands. He was diagnosed with bilateral AI. Based on positive screening for thrombocytosis and the Janus kinase 2 V617F mutation, he was diagnosed with ET. After low-dose aspirin therapy, he showed no symptom recurrence. The cortisol response in the adrenocorticotropic hormone stimulation test decreased at onset but improved after three months. Furthermore, abdominal CT revealed improvement in bilateral adrenal enlargement and enhancement. In patients presenting with AI, ET should be considered as a potential underlying disease, and early diagnosis and treatment is important to prevent recurrence.

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原发性血小板增多症患者双侧肾上腺梗死1例报告及简要文献复习。

肾上腺梗死（AI）是一种罕见的由肾上腺供血不足引起的疾病，很少有与原发性血小板增多症（ET）相关的报道。在这里，我们报告一例双侧AI作为ET患者的初始血栓并发症。一位69岁的男性，表现为右腹痛。腹部计算机断层扫描显示双侧肾上腺弥漫性肿大，增强不明显。他被诊断为双侧AI。基于血小板增多和Janus激酶2 V617F突变的阳性筛查，他被诊断为ET。在小剂量阿司匹林治疗后，他没有出现症状复发。促肾上腺皮质激素刺激试验中的皮质醇反应在发病时下降，但在3个月后改善。此外，腹部CT显示双侧肾上腺肿大和强化改善。在出现AI的患者中，ET应被视为潜在的潜在疾病，早期诊断和治疗对防止复发很重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

125

审稿时长

19 weeks

期刊介绍： Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.