{"title":"High output heart failure from an aortocaval fistula.","authors":"Laura Wubker Diaz, Shanice Spence-Miller, Rhea Sancassani, Arash Bornak, Rosario Colombo","doi":"10.1093/omcr/omag113","DOIUrl":"10.1093/omcr/omag113","url":null,"abstract":"<p><p>We report a 50-year-old male who sustained a right abdominal stab wound 20 years ago requiring laparotomy and extensive repair, now presenting with worsening dyspnea on exertion and palpitations. Physical examination was remarkable for jugular venous distention, bilateral lower extremity edema, and a right abdominal pulsatile mass with audible bruit. Transthoracic echocardiogram revealed a left ventricular ejection fraction (LVEF) of 30%-35% and a severely dilated inferior vena cava (IVC) with turbulent flow. Computed tomography venography of the abdomen revealed a fistula between the IVC and right renal artery, with aneurysm of the IVC measuring 8 cm. Cardiac catheterization confirmed a high cardiac output of 12 l/min. The patient underwent endovascular repair of the fistula with the use of an Amplatzer septal occluder, and subsequent improvement in symptoms and LVEF. This case highlights a unique etiology of high output heart failure, treated successfully by novel endovascular means.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag113"},"PeriodicalIF":0.6,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13343781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Giant cell myocarditis treated with long-term multi-modal care with multiple mechanical circulatory support: case report.","authors":"Motohiro Shingu, Nishikawa Tatsuya, Yuya Oga, Hibiki Kadohara, Yuto Osumi, Kenta Ishibashi, Mana Hiraishi, Mitsuo Kinugasa, Yasutaka Hirayama, Kinta Hatakeyama, Koichi Tamita","doi":"10.1093/omcr/omag110","DOIUrl":"10.1093/omcr/omag110","url":null,"abstract":"<p><p>We report the case of a 71-year-old woman with giant cell myocarditis presenting as acute heart failure and cardiogenic shock (LVEF 15%). She required mechanical ventilation, IMPELLA CP (Abiomed, Danvers, MA), veno-arterial extracorporeal (VA-ECMO), and continuous renal replacement therapy. Endomyocardial biopsy confirmed giant cell myocarditis, and treatment with corticosteroids, mycophenolate mofetil, and tacrolimus was initiated. Following multi-modal support and immunosuppressive therapy, left ventricular function recovered to 54%, allowing withdrawal of mechanical circulatory support and hemodialysis. However, the patient ultimately died on the 111th day due to the long treatment of cytomegalovirus infection and septic shock from catheter-related blood stream infection. Optimal immunosuppressive regimens remain undefined, so this case highlights successful recovery of cardiac function with intensive multi-modal management.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag110"},"PeriodicalIF":0.6,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13343777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection of occult non-mass enhancement in bloody nipple discharge using US/MRI fusion imaging: a case report.","authors":"Yukako Mouri, Masayuki Saito, Kanna Ozaki, Hirona Banno, Manami Goto, Mirai Ido, Takahito Ando, Junko Kousaka, Kimihito Fujii, Tsuneo Imai, Shogo Nakano, Takanori Ito, Emiko Takahashi, Koujiro Suzuki","doi":"10.1093/omcr/omag119","DOIUrl":"10.1093/omcr/omag119","url":null,"abstract":"<p><p>A 66-year-old woman presented with right bloody nipple discharge (BND). Initial evaluation, including palpation, mammography (MMG), ultrasonography (US), and cytology, revealed no abnormalities. In the second year, persistent BND prompted breast magnetic resonance imaging (MRI), which demonstrated non-mass enhancement in the lower right breast and was classified as Breast Imaging Reporting and Data System (BI-RADS) category 3; therefore, imaging surveillance was performed. In the third year, cytological examination revealed atypical cells. Repeat MRI again demonstrated non-mass enhancement. US/MRI fusion identified two suspicious regions; however, ultrasound-guided needle biopsy showed no evidence of malignancy. Because of persistent BND and cytological atypia, excisional biopsy was performed, and ductal carcinoma in situ (DCIS) was confirmed. US/MRI fusion may assist in localizing target areas for biopsy in patients with MRI-detected lesions without corresponding findings on MMG or US; however, histopathological confirmation remains essential.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag119"},"PeriodicalIF":0.6,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13343778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An unexpected sequel to happiness: happy heart syndrome.","authors":"Laith Rhabneh, Jamil Wafi, Ra'ed Ababneh, Shahd Qaddour, Mohammed Aloqaily, Abdel Rahman Alwardat, Khalid Hazaimeh","doi":"10.1093/omcr/omag108","DOIUrl":"10.1093/omcr/omag108","url":null,"abstract":"<p><p>Takotsubo cardiomyopathy (TCM) is characterized by transient regional systolic dysfunction without obstructive coronary artery disease. A rare subtype, happy heart syndrome (HHS), is triggered by positive emotional events. A 65-year-old woman with hypertension, diabetes mellitus, and dyslipidemia presented with typical anginal chest pain for three days, beginning after attending a wedding party. Initial clinic ECG showed anterolateral ST-segment elevation, prompting referral to the Emergency Department. On arrival, her chest pain had resolved, and repeated ECG demonstrated normalization of ST changes with QT prolongation and T-wave inversion. Troponin was elevated at 717 ng/l. Echocardiography showed an EF of 35% (baseline 58%) with apical and LAD-territory akinesia and ballooning. Coronary angiography revealed normal coronaries, while left ventricular angiography demonstrated findings consistent with TCM. Cardiac MRI excluded infarction or fibrosis. With guideline-directed therapy, EF recovered to 56% on follow-up.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag108"},"PeriodicalIF":0.6,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13343773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Nocardia farcinica</i> brain abscess in a patient with Evans syndrome: challenges in management.","authors":"Anjely Sebastian, Nitin Gupta, Pothumarthy Swathi Kiran, Barnini Banerjee, Muralidhar Varma, Vishwapriya Godkhindi, Tirlangi Praveen Kumar","doi":"10.1093/omcr/omag114","DOIUrl":"10.1093/omcr/omag114","url":null,"abstract":"<p><p>Cerebral nocardiosis is a rare but serious infection, often seen in immunocompromised individuals. This report discusses a case of cerebral nocardiosis in a woman with diabetes and Evans syndrome on immunosuppressive therapy. She presented with neurological symptoms, including seizures and hemiparesis, and brain imaging revealed abscesses. Surgical excision was done and culture confirmed <i>Nocardia farcinica</i>, showing resistance to co-trimoxazole. Treatment included a combination of intravenous and oral antibiotics, tailored based on susceptibility. The report highlights the need for prophylaxis in immunosuppressed patients to prevent opportunistic infections like nocardiosis. This case underscores the importance of early diagnosis, individualized therapy, and careful management of immunosuppression to improve outcomes.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 7","pages":"omag114"},"PeriodicalIF":0.6,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13343774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Challenges in diagnosing confluent and reticulated papillomatosis: a case of atypical lesions distribution.","authors":"","doi":"10.1093/omcr/omag123","DOIUrl":"10.1093/omcr/omag123","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/omcr/omaf142.].</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 6","pages":"omag123"},"PeriodicalIF":0.6,"publicationDate":"2026-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13309894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuropsychiatric-pharmacologic synergy: interaction between psychiatric polypharmacy and cancer treatment-related neurotoxicity.","authors":"Sean P Woytowitz, Charles Manchee","doi":"10.1093/omcr/omag107","DOIUrl":"10.1093/omcr/omag107","url":null,"abstract":"<p><p>Altered mental status (AMS) in oncology populations frequently reflects complex interactions among medical, pharmacologic, and neuropsychiatric factors. Accurate identification of the primary contributors is crucial to minimize morbidity. We report the case of a man in his 60s with a relapsed plasma cell malignancy, status post autologous stem-cell transplant, who experienced recurrent AMS during ongoing combination chemotherapy and psychiatric polypharmacy. Neuroimaging excluded structural or vascular lesions. Laboratory evaluation revealed intermittent mild renal dysfunction without metabolic crisis. His medication regimen included multiple serotonergic, dopaminergic, and sedative agents; clinical improvement followed medication rationalization. This case highlights the multifactorial nature of AMS in cancer survivors, in which post-transplant neuroinflammation, systemic metabolic stress, and overlapping drug effects create a brain vulnerable to toxic-metabolic encephalopathy. A systems-based, interdisciplinary approach is essential for diagnosing and preventing AMS in post-transplant oncology patients. Early recognition and medication simplification can reduce recurrence and enhance cognitive function.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 6","pages":"omag107"},"PeriodicalIF":0.6,"publicationDate":"2026-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13283428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vivek Jha, Pinaki Dutta, Ashley B Grossman, Byanjana Bashyal
{"title":"Central serous chorioretinopathy following intramuscular testosterone therapy in prolactinoma.","authors":"Vivek Jha, Pinaki Dutta, Ashley B Grossman, Byanjana Bashyal","doi":"10.1093/omcr/omag105","DOIUrl":"10.1093/omcr/omag105","url":null,"abstract":"","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 6","pages":"omag105"},"PeriodicalIF":0.6,"publicationDate":"2026-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13283426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Žymantas Jagelavičius, Jekaterina Strelčenko, Jelena Volochovič, Edvardas Žurauskas, Ričardas Janilionis
{"title":"A case of surgically treated recurrent spontaneous pneumothorax during pregnancy.","authors":"Žymantas Jagelavičius, Jekaterina Strelčenko, Jelena Volochovič, Edvardas Žurauskas, Ričardas Janilionis","doi":"10.1093/omcr/omag109","DOIUrl":"10.1093/omcr/omag109","url":null,"abstract":"<p><p>Spontaneous pneumothorax in pregnancy is a very uncommon condition, with fewer than 100 cases described in the English literature. This case report describes a pregnant woman who experienced two episodes of primary spontaneous pneumothorax during pregnancy. A 31-year-old, Caucasian pregnant woman (P2 G3 A1, gestational age 17<sup>+0</sup> weeks), conceived naturally, body mass index 28, a former smoker, arrived at the hospital with dyspnea and chest pain. Pneumothorax was detected and managed with a chest tube. However, three days after discharge, pneumothorax reoccurred. Due to a persistent air leak, video-assisted thoracoscopic surgery was performed. Histological examination revealed enlarged airspaces without any signs of specific lung pathology. Postoperative recovery was uneventful, and the patient delivered a healthy newborn without complications. This case highlights the importance of multidisciplinary, individualized diagnostic and treatment options in pregnant patients with primary spontaneous pneumothorax to prevent misdiagnosis and ensure optimal outcomes for both mother and fetus.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 6","pages":"omag109"},"PeriodicalIF":0.6,"publicationDate":"2026-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13283434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linh N-D Vo, Lee D Lam, Shotaro Naganawa, Ahmadreza Ghasemiesfe
{"title":"Clostridial necrotizing infection with multiorgan failure in an unhoused patient following a presumed spider bite.","authors":"Linh N-D Vo, Lee D Lam, Shotaro Naganawa, Ahmadreza Ghasemiesfe","doi":"10.1093/omcr/omag112","DOIUrl":"10.1093/omcr/omag112","url":null,"abstract":"<p><p>Spider bites are commonly encountered in medicine and, when recognized early, can often be effectively managed with supportive care or antivenom. However, in rare cases, particularly in individuals with poor living conditions, chronic comorbidities, or immunocompromised states, arachnid envenomation can act as a portal for rare but life-threatening complications. We introduce the case of a 59-year-old male who presented with a presumed spider bite and later developed necrotizing soft tissue infection complicated by compartment syndrome, acute mesenteric ischemia, septic shock, and multiorgan failure, including pulmonary edema, acute kidney injury, and hepatic dysfunction. This case highlights the importance of early recognition and multidisciplinary intervention in medically and socially complex patients, and underscores how structural vulnerability can both increase exposure risk and amplify clinical severity.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2026 6","pages":"omag112"},"PeriodicalIF":0.6,"publicationDate":"2026-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13283433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}