Tetrahedron最新文献_第5页

One-pot three-component construction of benzo[4,5]imidazo[1,2-a]benzo[4,5]thieno[3,2-d]pyrimidines through [5+1+3] cascade cyclization 通过[5+1+3]级联环化一锅三组分构建苯并[4,5]咪唑[1,2-a]苯并[4,5]噻唑[3,2-d]嘧啶

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-05 DOI: 10.1016/j.tet.2025.134811

Jiao Wang, Botao Wang, Ting Shao, Zheng Li

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Total Synthesis and Reconfirmation of the Absolute Configuration of Melanochromone 黑素素绝对构型的全合成与再确认

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-05 DOI: 10.1016/j.tet.2025.134808

Yuanwei You , Fei Tan , Zhijian Luo , Ting Peng , Yujiao He , Chunran Zhang , Yuchi Wang , Hongbo Dong

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Research progress in synthesis of Lepadiformine 左二福明的合成研究进展

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-03 DOI: 10.1016/j.tet.2025.134804

Xuesong Gu , Meng Zhao , Lanlan Sun , Ying Xiong

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Total synthesis of an elusive indole alkaloid isolated from Halichondria melanodocia 从黑藻中分离的一种难以捉摸的吲哚生物碱的全合成

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-03 DOI: 10.1016/j.tet.2025.134800

Javier Rivera-Mendoza , Ángel A. Nolasco-Hernández , Leticia Quintero , Vladimir Carranza-Téllez , Fernando Sartillo-Piscil

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Synthesis of very large cavitand-based bimolecular capsules 超大空腔基双分子胶囊的合成

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-03 DOI: 10.1016/j.tet.2025.134807

Zsolt Csók , Leonidas-Dimitrios Syntrivanis , Naidel A.M.S. Caturello , Rodrigo Q. Albuquerque , László Kollár

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Engaging aliphatic mesylates in Suzuki-Miyaura cross-coupling for late-stage functionalization 在Suzuki-Miyaura交叉偶联中参与脂肪族甲酰基化合物的后期功能化

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-03 DOI: 10.1016/j.tet.2025.134805

Chloe D. Wong, Lauren C. Bradford, Elizabeth R. Jarvo

引用次数: 0

Design and synthesis of air-stable, storable chiral phosphoramidite ligands for transition-metal-catalyzed enantioselective reactions 过渡金属催化对映选择反应中空气稳定、可储存的手性磷酰胺配体的设计与合成

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-03 DOI: 10.1016/j.tet.2025.134797

Nasiri Behzad , Ashouri Akram , Waser Mario

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Photoredox-HAT catalysed α-C–H alkylation of primary amines with vinyl phosphine oxides: New building blocks for spiropyrrolidine synthesis 光氧化还原- hat催化伯胺与乙烯基膦氧化物的α-C-H烷基化：合成螺吡咯烷的新组成部分

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-07-01 DOI: 10.1016/j.tet.2025.134806

Anna G. Kinsella , Joseph J. Bell-Tyrer , Darren Stead , Alexander J. Cresswell

引用次数: 0

Cp∗Ir(III) Catalyzed greener synthesis of nitrogenous heterocycles using acceptor less dehydrogenative coupling (ADC) strategy Cp * Ir（III）用少受体脱氢偶联（ADC）策略催化更环保的含氮杂环化合物合成

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-06-30 DOI: 10.1016/j.tet.2025.134799

Md Bakibillah , Rahul Kumar Singh , Dilip Sarkar , Deboshmita Mukherjee , Saranita Roy Chowdhury , Sumana Roy , Mahboob Alam , Mohammad Shahidul Islam , Rajesh Kumar Das

{"title":"Cp∗Ir(III) Catalyzed greener synthesis of nitrogenous heterocycles using acceptor less dehydrogenative coupling (ADC) strategy","authors":"Md Bakibillah , Rahul Kumar Singh , Dilip Sarkar , Deboshmita Mukherjee , Saranita Roy Chowdhury , Sumana Roy , Mahboob Alam , Mohammad Shahidul Islam , Rajesh Kumar Das","doi":"10.1016/j.tet.2025.134799","DOIUrl":"10.1016/j.tet.2025.134799","url":null,"abstract":"<div><div>In our preliminary research, we demonstrated excellent catalytic activity of Ir(III) complexes coordinated via a picolinamidato moiety. Utilizing these catalysts, we efficiently synthesized α-alkylated ketones through the hydrogen-borrowing methodology, employing ketones and secondary alcohols in the presence of primary alcohols. Furthermore, we successfully applied an acceptor less dehydrogenative coupling (ADC) strategy using the same series of in-house synthesized Ir(III) catalysts to generate a variety of nitrogen-containing heterocycles, including quinoline, pyrrole, and pyridine derivatives under neat (solvent-free) conditions at 90 °C. Encouraged by these results, we extended the catalytic system to the synthesis of additional nitrogen-rich heterocyclic frameworks such as pyrido[2,3-<em>b</em>]pyrazine, 1,8-naphthyridine, and quinazolin-4(3<em>H</em>)-one derivatives, achieving good to excellent yields. This methodology is particularly attractive due to its environmentally benign nature requiring only a small amount of catalyst (0.3 mol%), base (0.2 mol%) and producing only non-toxic by-products H<sub>2</sub> and H<sub>2</sub>O. Overall, this work contributes to the development of sustainable and green synthetic approaches for the construction of valuable nitrogen-containing heterocycles.</div></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"185 ","pages":"Article 134799"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and characterization of coumarin derivatives for chemosensor application via experimental and theoretical approaches 香豆素衍生物在化学传感器中的合成与表征

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-06-26 DOI: 10.1016/j.tet.2025.134796

Mahesh Madar , Venkatesan Srinivasan , Manjunath P. Eelager , Nagarjuna Prakash Dalbanjan , Kavyashree Nagappa Kummur , Venugopala Nayak , Mahantesh M. Basanagouda , Ashok Sidarai

{"title":"Synthesis and characterization of coumarin derivatives for chemosensor application via experimental and theoretical approaches","authors":"Mahesh Madar , Venkatesan Srinivasan , Manjunath P. Eelager , Nagarjuna Prakash Dalbanjan , Kavyashree Nagappa Kummur , Venugopala Nayak , Mahantesh M. Basanagouda , Ashok Sidarai","doi":"10.1016/j.tet.2025.134796","DOIUrl":"10.1016/j.tet.2025.134796","url":null,"abstract":"<div><div>Coumarin-based fluorescence probes are potential candidates for selective sensing of explosive materials and toxins. In this present study, we designed and developed novel coumarin derivatives with minor modifications from coumarin and sesamol by a simple condensation method. Moreover, the prepared coumarin derivatives, such as <strong>6BMC</strong> and <strong>7BMC</strong> were characterized by different spectroscopic analyses. The photophysical properties were analyzed through steady-state absorption and fluorescence spectral studies. The substitution of a methyl group strongly affects the non-radiative deactivation as a result, the hyperconjugation increases for <strong>7BMC</strong> than <strong>6BMC</strong>. The fluorescence probe was used to detect numerous nitroaromatic compounds and demonstrated a rapid, highly selective, and sensitive fluorescence 'Turn Off' response to picric acid (PA) in a THF/H<sub>2</sub>O solution, among other nitroaromatics. The fluorescence \"Turn Off\" response in the presence of PA is due to the photoinduced electron transfer, as proven by lifetime measurements and DFT analysis. The calculated limit of detection is 0.36 and 0.57 μM for <strong>6BMC</strong> and <strong>7BMC</strong>, respectively. The findings indicate that the coumarin derivatives are efficient probes for selective sensing of picric acid at a micromolar level.</div></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"185 ","pages":"Article 134796"},"PeriodicalIF":2.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0