Tetrahedron最新文献_第6页

Synthesis and evaluation of new isoquinoline diimide derivatives as small molecule acceptors for organic solar cells 新型异喹啉二亚胺衍生物作为有机太阳能电池小分子受体的合成与评价

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-25 DOI: 10.1016/j.tet.2025.134616

Alberto Insuasty , Serena Carrara , Doan Vu , Joel José Montalvo-Acosta , Alejandro Ortíz , Conor Hogan , Christopher R. McNeill , Steven J. Langford

{"title":"Synthesis and evaluation of new isoquinoline diimide derivatives as small molecule acceptors for organic solar cells","authors":"Alberto Insuasty , Serena Carrara , Doan Vu , Joel José Montalvo-Acosta , Alejandro Ortíz , Conor Hogan , Christopher R. McNeill , Steven J. Langford","doi":"10.1016/j.tet.2025.134616","DOIUrl":"10.1016/j.tet.2025.134616","url":null,"abstract":"<div><div>In this work we explore the use of the method of oxidation and heterocyclization of naphthalene diimides (NDIs) to obtain five novel isoquinoline diimide derivatives (<strong>IQDI 3</strong>–<strong>7</strong>) as new small molecule acceptors. These derivatives comprise a main core based on triphenylamine (TPA) as electron-donor linked to an isoquinoline diimide moiety as a new electron-acceptor (<strong>IQDI 3</strong>). The effect on the electronic properties of a further functionalization on TPA achieving A-D-A architectures with additional electron acceptors moieties such as carbonyl group (<strong>IQDI 4</strong>), 3-methylrhodanine (<strong>IQDI 5</strong>), 1,3-indandione (<strong>IQDI 6</strong>) and malononitrile (<strong>IQDI 7</strong>) was studied. Their electrochemical and optoelectronic properties as well as their performance in photovoltaic devices using <strong>J52</strong> as electron-donor polymer were studied being <strong>IQDI 6</strong> the compound that showed the best PCE % value.</div></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"178 ","pages":"Article 134616"},"PeriodicalIF":2.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Studies toward the synthesis of yaretol: an unexpected rearrangement en route to the tricyclic core yaretol合成的研究：通往三环核心的意外重排

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-25 DOI: 10.1016/j.tet.2025.134619

C. Elizabeth Adams, Steven D. Townsend

引用次数: 0

Synthesis of the ACDE tetracyclic skeleton in ceforalide B 头孢醛乙酯ACDE四环骨架的合成

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-25 DOI: 10.1016/j.tet.2025.134618

Xiao-Wei Cong , Yu Peng

引用次数: 0

Visible-light-driven synthesis of benzoxepine derivatives from aromatic diazo compounds 芳香族重氮化合物的可见光驱动合成苯并西平衍生物

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-25 DOI: 10.1016/j.tet.2025.134620

Xiuyuan Duan, Guojun Zheng

引用次数: 0

Editorial for the special issue commemorating the 90th birthday of Dr A V Rama Rao 纪念拉玛·拉奥博士90岁生日特刊社论

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-25 DOI: 10.1016/j.tet.2025.134613

B.V. Subba Reddy

引用次数: 0

A new sesquiterpene with a specialized [4,4] bicyclononane skeleton from the marine-derived fungus Metarhizium sp. P2100 海洋真菌Metarhizium sp. P2100中一种具有特殊[4,4]双环壬烷骨架的倍半萜

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-22 DOI: 10.1016/j.tet.2025.134607

Zhong-Lian Ma , Zhi-Pu Yu , Ling Lv , Zhi-Qing Liu , Chang-Yun Wang , Guang-Shan Yao

引用次数: 0

Imidazole-mediated defluorosulfonylation of N-(fluorosulfonyl)oxazolidinones accessed by an organoiodine(I/III)-catalyzed oxyamination 咪唑介导的N-（氟磺酰基）恶唑烷酮的去氟磺化，有机碘（I/III）催化氧化胺化

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-22 DOI: 10.1016/j.tet.2025.134611

Hiroto Kimura , Takuya Hashimoto

引用次数: 0

Stereoselective synthesis of novel 4′-methylsulfanyl-pyrimidine ribonucleosides by means of nucleophilic substitution of the 4′-benzoyloxy leaving group 用亲核取代4′-苯甲酰氧基离去基立体选择性合成新型4′-甲基磺酰嘧啶核糖核苷

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-21 DOI: 10.1016/j.tet.2025.134581

Kazuhiro Haraguchi , Yasuaki Kimura , Hiroshi Abe , Hiroki Kumamoto , Hiromichi Tanaka

{"title":"Stereoselective synthesis of novel 4′-methylsulfanyl-pyrimidine ribonucleosides by means of nucleophilic substitution of the 4′-benzoyloxy leaving group","authors":"Kazuhiro Haraguchi , Yasuaki Kimura , Hiroshi Abe , Hiroki Kumamoto , Hiromichi Tanaka","doi":"10.1016/j.tet.2025.134581","DOIUrl":"10.1016/j.tet.2025.134581","url":null,"abstract":"<div><div>A synthetic route for the novel nucleosides 4′-methylsulfanyluridine (<strong>20a</strong>) and –cytidine (<strong>26</strong>) has been developed. This route consists of two steps; 1) preparation of 4′-<em>O</em>-benzoyloxy-xylofuranosylnucleoside <strong>13</strong> through electrophilic iodo-benzoyloxylation to 4′,5′-unsaturated uracil nulesoside <strong>9</strong> and replacement of the iodo-substituent at the 5′-position with the benzoyloxy group, 2) nucleophilic substitution of <strong>13</strong> with Me<sub>3</sub>SiSMe leading to the 4′-α-methylsulfanylnucleoside <strong>14a</strong> stereoselectively. The possible reaction mechanism of the 5′-deoxy-5′-iodonucleosides <strong>10a</strong> and <strong>10b</strong> with AgOBz is discussed. The transformation of the xylofuranosyl moiety of <strong>14a</strong> into the ribonucleoside <strong>20a</strong> was performed on the basis of the ring-opening of the <em>O</em><sup>2</sup>,2′-anhydronucleoside <strong>24</strong> with benzoate ion. In this study, 4′-methylsulfanylcytidine <strong>26</strong> was also synthesized.</div></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"179 ","pages":"Article 134581"},"PeriodicalIF":2.1,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conduritols: Synthesis strategies from classic to contemporary Conduritols：从古典到现代的综合策略

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-21 DOI: 10.1016/j.tet.2025.134605

Soumyadip Malik , Amrit Krishna Mitra

{"title":"Conduritols: Synthesis strategies from classic to contemporary","authors":"Soumyadip Malik , Amrit Krishna Mitra","doi":"10.1016/j.tet.2025.134605","DOIUrl":"10.1016/j.tet.2025.134605","url":null,"abstract":"<div><div>Conduritols, cyclic polyols with diverse biological activities, have garnered significant attention since their discovery over a century ago. These compounds, comprising six isomers (A, B, C, D, E, and F), possess unique structural and stereochemical properties, with only A and F naturally occurring. Conduritols and their derivatives serve as essential precursors for biologically significant molecules, including cyclitols, pseudo-sugars, and phosphorylated inositols. Their applications span a wide range of biological processes, such as glycosidase inhibition, insulin modulation, and signal transduction, making them promising candidates for therapeutic interventions in diabetes, cancer, and HIV/AIDS.</div><div>Synthetic advancements have enabled the preparation of all conduritol isomers, employing innovative approaches like aromatic diol transformations and stereocontrolled reactions. These methods have unlocked efficient pathways to biologically potent compounds, including pancratistatin, narciclasine, and aminoglycosidic antibiotics. This review provides an overview of the historical progress, synthetic methodologies, and biological significance of conduritols. Recent innovations in stereospecific synthesis are highlighted, showcasing the potential for large-scale production of optically pure conduritols to meet growing biomedical demands. This study aims to highlight advancements in conduritol synthesis, focusing on evolving methodologies and stereoselectivity challenges.</div></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"178 ","pages":"Article 134605"},"PeriodicalIF":2.1,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143686418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-pot synthesis of 3,4-dihydroisoquinolin-1(2H)-ones via a sequential Ugi-4CR and nucleophilic substitution reaction 通过顺序Ugi-4CR和亲核取代反应一锅合成3,4-二氢异喹啉-1(2H)- 1

IF 2.1 3区化学

Tetrahedron Pub Date : 2025-03-21 DOI: 10.1016/j.tet.2025.134609

Hong-Ling Pan, Han-Han Kong, Ming-Wu Ding

引用次数: 0