Recent developments in the synthesis of amidines

Amidines are a common functionality found in a variety of naturally occurring compounds, valuable bioactive molecules, and pharmaceuticals. Synthesis of amidine derivatives has attracted considerable attention by organic chemists in recent years due to their wide potential applications, especially in medicinal chemistry, making them an exciting candidate for drug discovery. In this review, we have compiled the latest advances reported over the last few years for the synthesis of amidines (2018–present), focusing on diverse synthetic pathways conducted under different conditions. This provides valuable information for understanding the chemistry of amidine derivatives, offering insights into their potential as key intermediates for the development of novel bioactive compounds and pharmaceutical agents.