芴及其类似物的合成综述

IF 2.2 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2025-08-28 DOI:10.1016/j.tet.2025.134896

Sreenivasulu Chinnabattigalla , Ravi Kishore Dakoju , Satyanarayana Gedu

{"title":"芴及其类似物的合成综述","authors":"Sreenivasulu Chinnabattigalla , Ravi Kishore Dakoju , Satyanarayana Gedu","doi":"10.1016/j.tet.2025.134896","DOIUrl":null,"url":null,"abstract":"<div><div>Fluorenes represent an essential class of fused tricyclic aromatic compounds embedded with two aromatic rings, with diverse applications in organic electronics, pharmaceuticals, and functional materials. Recent advancements in their synthesis have introduced efficient methodologies, including transition-metal catalysis, oxidative cascade processes, and carbene-mediated transformations. These strategies enabled precise structural modifications, facilitating access to highly functionalized fluorenes with tailored electronic and optical properties. Additionally, novel enantioselective approaches have broadened the scope for synthesizing chiral fluorene derivatives. This review provides a comprehensive overview of these synthetic advancements from 2021 to 2025, highlighting key reaction mechanisms, functional group compatibility, and their broader impact on materials and medicinal chemistry.</div></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":"187 ","pages":"Article 134896"},"PeriodicalIF":2.2000,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A recent overview of the synthesis of fluorenes and their analogs\",\"authors\":\"Sreenivasulu Chinnabattigalla , Ravi Kishore Dakoju , Satyanarayana Gedu\",\"doi\":\"10.1016/j.tet.2025.134896\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Fluorenes represent an essential class of fused tricyclic aromatic compounds embedded with two aromatic rings, with diverse applications in organic electronics, pharmaceuticals, and functional materials. Recent advancements in their synthesis have introduced efficient methodologies, including transition-metal catalysis, oxidative cascade processes, and carbene-mediated transformations. These strategies enabled precise structural modifications, facilitating access to highly functionalized fluorenes with tailored electronic and optical properties. Additionally, novel enantioselective approaches have broadened the scope for synthesizing chiral fluorene derivatives. This review provides a comprehensive overview of these synthetic advancements from 2021 to 2025, highlighting key reaction mechanisms, functional group compatibility, and their broader impact on materials and medicinal chemistry.</div></div>\",\"PeriodicalId\":437,\"journal\":{\"name\":\"Tetrahedron\",\"volume\":\"187 \",\"pages\":\"Article 134896\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tetrahedron\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0040402025004521\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040402025004521","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

芴是一类嵌有两个芳香环的三环芳香族化合物，在有机电子、医药和功能材料中有着广泛的应用。最近在合成方面的进展引入了有效的方法，包括过渡金属催化、氧化级联过程和碳介导的转化。这些策略实现了精确的结构修改，便于获得具有定制电子和光学特性的高度功能化芴。此外，新的对映选择方法扩大了合成手性芴衍生物的范围。本文综述了2021 - 2025年间这些合成进展，重点介绍了关键反应机制、官能团相容性及其对材料和药物化学的广泛影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A recent overview of the synthesis of fluorenes and their analogs

查看原文本刊更多论文

A recent overview of the synthesis of fluorenes and their analogs

Fluorenes represent an essential class of fused tricyclic aromatic compounds embedded with two aromatic rings, with diverse applications in organic electronics, pharmaceuticals, and functional materials. Recent advancements in their synthesis have introduced efficient methodologies, including transition-metal catalysis, oxidative cascade processes, and carbene-mediated transformations. These strategies enabled precise structural modifications, facilitating access to highly functionalized fluorenes with tailored electronic and optical properties. Additionally, novel enantioselective approaches have broadened the scope for synthesizing chiral fluorene derivatives. This review provides a comprehensive overview of these synthetic advancements from 2021 to 2025, highlighting key reaction mechanisms, functional group compatibility, and their broader impact on materials and medicinal chemistry.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.