Nutrition Research and Practice最新文献

{"title":"Development and validation of a semi-quantitative food frequency questionnaire as a tool for assessing dietary vitamin D intake among Korean women.","authors":"Hye Ran Shin, SuJin Song, Sun Yung Ly","doi":"10.4162/nrp.2024.18.6.872","DOIUrl":"10.4162/nrp.2024.18.6.872","url":null,"abstract":"<p><strong>Background/objectives: </strong>Appropriate vitamin D status improves bone health and chronic diseases; it has shown benefits during the coronavirus disease 2019 pandemic. Therefore, assessing vitamin D status is crucial. However, limited research on vitamin D intake among Koreans complicates understanding of its consumption. This study aimed to develop and validate a semi-quantitative food frequency questionnaire (FFQ) to assess vitamin D intake among Koreans.</p><p><strong>Subjects/methods: </strong>A vitamin D FFQ was developed to include 31 vitamin D source foods from 8 food groups frequently consumed by Korean adults. The study included 152 women residing in a major city in South Korea. From September 2020 to August 2022, intake was surveyed using a 12-day dietary record (12-day DR) across 4 seasons, and 2 vitamin D FFQs were conducted approximately 9-11 months apart (FFQ1 and FFQ2). Reproducibility (FFQ1 vs. FFQ2) and validity (FFQ2 vs. 12-day DR) were verified using Spearman's rank correlation, weighted kappa coefficient, intraclass correlation, and Bland-Altman plots.</p><p><strong>Results: </strong>The vitamin D intake of Korean women using the newly developed vitamin D FFQ was higher at FFQ1 (4.90 µg/day) and FFQ2 (4.58 µg/day) compared with the 12-day DR (4.07 µg/day). Additionally, the results for reproducibility and validity were demonstrated through the Spearman's rank correlation coefficient (reproducibility, 0.592; validity, 0.460), weighted kappa coefficient (reproducibility, 0.379; validity, 0.284), intraclass correlation coefficient (reproducibility, 0.599; validity, 0.543), and Bland-Altman plots (reproducibility index, 3.95%; validity index, 3.95%).</p><p><strong>Conclusion: </strong>This study confirmed the newly developed vitamin D FFQ is reliable and valid for assessing vitamin D intake among Korean women. These results suggest the FFQ is an effective tool for dietary assessment, particularly in large-scale studies where year-round monitoring may not be feasible. Further validation in Korean men is crucial to enhance its applicability, enabling significant contributions to assessing vitamin D intake among Korean adults.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 6","pages":"872-884"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11621432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daily consumption of specific categories of fruit and vegetables negatively correlated with frailty: findings from the US National Health and Nutrition Examination Survey.","authors":"Xiaofeng Zhang, Junmei Lai, Zhenhua Jin, Yanfei Wu, Kun Zhao","doi":"10.4162/nrp.2024.18.6.829","DOIUrl":"10.4162/nrp.2024.18.6.829","url":null,"abstract":"<p><strong>Background/objectives: </strong>The specific impact of different fruit and vegetable consumption categories on frailty is not completely understood. This study examined the relationships between the daily consumption of fruit and vegetables and frailty in a large general population.</p><p><strong>Subjects/methods: </strong>This study used the data from the US National Health and Nutrition Examination Survey (2005-2020). Two intermittent 24-h dietary recalls were used to evaluate fruit and vegetable consumption. Frailty was assessed using the frailty index. Logistic regression, stratified analyses, and restricted cubic spline models were used to examine these associations.</p><p><strong>Results: </strong>A higher daily intake of citrus, melons, and berries (odds ratio [OR], 0.77; 95% confidence interval [CI], 0.65-0.92), other fruit (OR, 0.74; 95% CI, 0.62-0.88), intact fruit (OR, 0.71; 95% CI, 0.60-0.84), dark-green vegetables (OR, 0.71; 95% CI, 0.60-0.83), and total vegetables (OR, 0.80; 95% CI, 0.66-0.96), along with a lower fruit juice intake (OR, 0.81; 95% CI, 0.69-0.96), were associated with a reduced risk of frailty in adults aged 18 yrs and older. Further analysis showed that the daily consumption of citrus melons and berries, other fruit, intact fruit, fruit juice, and tomatoes and tomato products were inversely associated with frailty in adults under 60 yrs and females. Dark green vegetables were inversely correlated with frailty in individuals aged 40-60 yrs and over 60 yrs, regardless of sex.</p><p><strong>Conclusion: </strong>The daily consumption of most types of fruit, dark green vegetables, and tomatoes and tomato products may reduce the risk of frailty in American adults, particularly for individuals under 60 yrs of age and females.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 6","pages":"829-844"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11621436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of quercetin nanoemulsion on SIRT1 activation and mitochondrial biogenesis in the skeletal muscle of high-fat diet-fed mice.","authors":"Mak-Soon Lee, Miae Doo, Yangha Kim","doi":"10.4162/nrp.2024.18.6.806","DOIUrl":"10.4162/nrp.2024.18.6.806","url":null,"abstract":"<p><strong>Background/objectives: </strong>Quercetin (QT) is a plant flavonoid that offers health benefits owing to its various bioactive properties; however, as a hydrophobic substance, it has considerably low bioavailability. We previously demonstrated that QT nanoemulsion (QT+NE) formulated via oil-in-water nanoemulsification exhibited more effective cholesterol-lowering activity than ordinary QT in high cholesterol-fed rats. In this study, we investigated the effects of QT+NE on the regulation of skeletal muscle mitochondrial function in high-fat diet (HD)-fed mice.</p><p><strong>Materials/methods: </strong>C57BL/6J mice were fed a normal chow diet (ND), HD (45% of calories from fat), or HD with 0.05% QT+NE or QT for 11 weeks. We analyzed sirtuin 1 (SIRT1) activation, mitochondrial changes, and the expression of genes involved in mitochondrial biogenesis in skeletal muscle.</p><p><strong>Results: </strong>Body weight and body weight gain decreased in the QT+NE group compared with that in the HD group (<i>P</i> < 0.05), but not in the QT group. Epididymal adipose tissue weight decreased in both the QT and QT+NE groups (<i>P</i> < 0.05). Plasma lipid levels also improved in both the QT and QT+NE groups (<i>P</i> < 0.05). QT+NE intake upregulated the messenger RNA levels of SIRT1, peroxisome proliferator-activated receptor-γ coactivator 1-α, nuclear respiratory factor 1, and mitochondrial transcription factor A in skeletal muscle compared with HD intake alone (<i>P</i> < 0.05), whereas QT did not. In particular, SIRT1 activity was significantly increased in the QT+NE group compared with that in the QT group (<i>P</i> < 0.05). HD intake reduced mitochondrial DNA content compared with ND intake; nevertheless, QT+NE intake retained it (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Collectively, our findings suggest that QT+NE may be beneficial in enhancing mitochondrial biogenesis in skeletal muscle of HD-fed mice, which may be associated with SIRT1 activation.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 6","pages":"806-817"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11621433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of the Korean Healthy Eating Index and sleep duration with prediabetes in middle-aged adults.","authors":"Ji-Myung Kim, Yun-Jung Bae","doi":"10.4162/nrp.2024.18.6.857","DOIUrl":"10.4162/nrp.2024.18.6.857","url":null,"abstract":"<p><strong>Background/objectives: </strong>Sleep duration and diet quality are reportedly associated with the risk of diabetes. This study aimed to examine the risk of diabetes according to sleep duration and diet quality in middle-aged Koreans.</p><p><strong>Subjects/methods: </strong>Using the Korea National Health and Nutrition Examination Survey 2019-2020, raw data from 2,934 participants aged 40-64 yrs (1,090 men and 1,844 women) who were not diagnosed with type 2 diabetes were analyzed. With a sleep duration of 7-7.9 h per night as the referent category, diet quality was assessed using the Korean Healthy Eating Index (KHEI), which comprises adequacy, moderation, and energy balance.</p><p><strong>Results: </strong>The study results showed that individuals with a short sleep duration had significantly higher blood glucose (<i>P</i> = 0.034) and HbA1c levels (<i>P</i> < 0.001) than those had by individuals with a sleep duration of 7-7.9 h. Within the group with a sleep duration of 7-7.9 h, the lowest quintile of the KHEI score had a significantly higher risk of prediabetes than that had by the highest quintile of the KHEI score (Model 1: odds ratio [OR], 1.775; 95% confidence interval [CI], 1.072-2.939; <i>P</i> < 0.05 and Model 2: OR, 1.731; 95% CI, 1.040-2.882; <i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Our findings suggest that achieving the sleep duration of 7-7.9 h and eating good diet are associated with the lowest risk of prediabetes. We recommend that the results of this study be used to educate adults aged 40-64 yrs on diet and lifestyle habits to prevent diabetes.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 6","pages":"857-871"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11621439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Carthamus tinctorius</i> seeds-<i>Taraxacum coreanum</i> combination attenuates scopolamine-induced memory deficit through regulation of inflammatory response and cholinergic function.","authors":"Mei Tong He, Yu-Su Shin, Hyun Young Kim, Eun Ju Cho","doi":"10.4162/nrp.2024.18.5.647","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.5.647","url":null,"abstract":"<p><strong>Background/objectives: </strong>There is growing interest in herbal medicines for managing age-related diseases, such as Alzheimer's and Parkinson's. Safflower seeds (<i>Carthamus tinctorius</i> L. seeds, CTS) and dandelions (<i>Taraxacum coreanum</i>, TC) are widely used to treat bone- or inflammation-related diseases in Oriental countries. This study investigated the protective effect of the CTS-TC combination on scopolamine (Sco)-induced memory deficits through inflammatory response and cholinergic function. Moreover, marker components such as serotonin, <i>N</i>-(<i>p</i>-coumaroyl) serotonin, <i>N</i>-feruloylserotonin, chlorogenic acid, and chicoric acid in the CTS-TC combination were analyzed for their potential benefits on memory function.</p><p><strong>Materials/methods: </strong>Water extracts of CTS, TC, and the CTS-TC combination at various ratios (4:1, 1:1, and 1:4) (100 mg/kg) were orally administered to mice for 14 days. Sco (1 mg/kg) was intraperitoneally injected into the mice before each behavioral test. T-maze and novel object recognition tests were conducted to monitor behavioral changes after the treatment. Western blotting was performed to detect protein expression. In addition, the presence of 5 biomarkers, serotonin, <i>N</i>-(<i>p</i>-coumaroyl) serotonin, <i>N</i>-feruloylserotonin, chlorogenic acid, and chicoric acid, was analyzed using high-performance liquid chromatography (HPLC).</p><p><strong>Results: </strong>Behavioral tests showed that the CTS-TC combination enhanced memory function in Sco-injected mice. Inflammation-related proteins (inducible nitric oxide synthase, cyclooxygenase-2, and glial fibrillary acidic protein) were downregulated after treatment with the CTS-TC combination. The acetylcholinesterase protein expression was also downregulated. HPLC analysis revealed that <i>N</i>-feruloylserotonin and chicoric acid were the predominant components, followed by <i>N</i>-(<i>p</i>-coumaroyl) serotonin, chlorogenic acid, and serotonin.</p><p><strong>Conclusion: </strong>These findings suggest that the CTS-TC combination protects against Sco-induced memory deficits by inhibiting inflammatory responses and cholinergic dysfunction. <i>N</i>-feruloylserotonin and chicoric acid, along with <i>N</i>-(<i>p</i>-coumaroyl) serotonin, chlorogenic acid, and serotonin, might be biomarkers for the CTS-TC combination, and their effects on memory protection warrant further study.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 5","pages":"647-662"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142470990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary ellagic acid blocks inflammation-associated atherosclerotic plaque formation in cholesterol-fed apoE-deficient mice.","authors":"Sin-Hye Park, Min-Kyung Kang, Dong Yeon Kim, Soon Sung Lim, Young-Hee Kang","doi":"10.4162/nrp.2024.18.5.617","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.5.617","url":null,"abstract":"<p><strong>Background/objectives: </strong>Atherosclerosis particularly due to high circulating level of low-density lipoprotein is a major cause of cardiovascular diseases. Ellagic acid is a natural polyphenolic compound rich in pomegranates and berries. Our previous study showed that ellagic acid improved functionality of reverse cholesterol transport in murine model of atherosclerosis. The aim of this study is to investigate whether ellagic acid inhibited inflammation-associated atherosclerotic plaque formation in cholesterol-fed apolipoprotein E (apoE)-knockout (KO) mice.</p><p><strong>Materials/methods: </strong>Wild type mice and apoE-KO mice were fed a cholesterol-rich Paigen diet for 10 weeks to induce severe atherosclerosis. Concurrently, 10 mg/kg ellagic acid was orally administered to the apoE-KO mice. Plaque lesion formation and lipid deposition were examined by staining with hematoxylin and eosin, Sudan IV and oil red O.</p><p><strong>Results: </strong>The plasma leukocyte profile of cholesterol-fed mice was not altered by apoE deficiency. Oral administration of ellagic acid attenuated plaque lesion formation and lipid deposition in the aorta tree of apoE-KO mice. Ellagic acid substantially reduced plasma levels of soluble vascular cell adhesion molecule and interferon-γ in Paigen diet-fed apoE-KO mice. When 10 mg/kg ellagic acid was administered to cholesterol-fed apoE-KO mice, the levels of CD68 and MCP-1 were strongly reduced in aorta vessels. The protein expression level of nitric oxide synthase-2 (NOS2) in the aorta was highly enhanced by supplementation of ellagic acid to apoE-KO mice, but the expression level of heme oxygenase-1 (HO-1) in the aorta was reduced. Furthermore, ellagic acid diminished the increased aorta expression of the inflammatory adhesion molecules in cholesterol-fed apoE-KO mice. The treatment of ellagic acid inhibited the scavenger receptor-B1 expression in the aorta of apoE-KO mice, while the cholesterol efflux-related transporters were not significantly changed.</p><p><strong>Conclusion: </strong>These results suggest that ellagic acid may be an atheroprotective compound by attenuating apoE deficiency-induced vascular inflammation and reducing atherosclerotic plaque lesion formation.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 5","pages":"617-632"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A combination of red and processed meat intake and polygenic risk score influences the incidence of hyperuricemia in middle-aged Korean adults.","authors":"Suyeon Lee, Dayeon Shin","doi":"10.4162/nrp.2024.18.5.721","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.5.721","url":null,"abstract":"<p><strong>Background/objectives: </strong>The high consumption of purine-rich meat is associated with hyperuricemia. However, there is limited evidence linking the consumption of red and processed meat to the genetic risk of hyperuricemia. We investigated the relationship between various combinations of red and processed meat consumption and the polygenic risk scores (PRSs) and the incidence of hyperuricemia in middle-aged Koreans.</p><p><strong>Subjects/methods: </strong>We analyzed the data from 44,053 participants aged ≥40 years sourced from the Health Examinees (HEXA) cohort of the Korean Genome and Epidemiology Study (KoGES). Information regarding red and processed meat intake was obtained using a semiquantitative food frequency questionnaire (SQ-FFQ). We identified 69 independent single-nucleotide polymorphisms (SNPs) at uric acid-related loci using genome-wide association studies (GWASs) and clumping analyses. The individual PRS, which is the weighted sum of the effect size of each allele at the SNP, was calculated. We used multivariable Cox proportional hazards models adjusted for covariates to determine the relationship between red and processed meat intake and the PRS in the incidence of hyperuricemia.</p><p><strong>Results: </strong>During an average follow-up period of 5 years, 2,556 patients with hyperuricemia were identified. For both men and women, the group with the highest red and processed meat intake and the highest PRS was positively associated with the development of hyperuricemia when compared with the group with the lowest red and processed meat intake and the lowest PRS (hazard ratio [HR], 2.72; 95% confidence interval [CI], 2.10-3.53; <i>P</i> < 0.0001; HR, 3.28; 95% CI, 2.45-4.40; <i>P</i> < 0.0001).</p><p><strong>Conclusion: </strong>Individuals at a high genetic risk for uric acid levels should moderate their consumption of red and processed meat to prevent hyperuricemia.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 5","pages":"721-745"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consumption of poly-γ-glutamate-vitamin B6 supplement and urinary microbiota profiles in Korean healthy adults: a randomized, double-blinded, placebo-controlled intervention study.","authors":"Jungmin Park, Inkyung Baik","doi":"10.4162/nrp.2024.18.5.663","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.5.663","url":null,"abstract":"<p><strong>Background/objectives: </strong>Poly-γ-glutamic acid (γ-PGA), a natural polymer found in fermented soybean products, has been reported to play a prebiotic role in the gut. This intervention study investigated the effects of γ-PGA-containing supplement consumption on urinary microbiota in healthy adults because of limited data on such investigation.</p><p><strong>Subjects/methods: </strong>A 4-week parallel trial including 39 male and female Korean adults, who were free of chronic diseases and infection, was designed as a randomized, double-blinded, placebo-controlled study. A total of 30 participants completed the study wherein the intervention group (n = 17) received a mixture supplement containing 600 mg/day of γ-PGA and 100 mg/day of vitamin B6, while the control group (n = 13) received a placebo. Paired datasets (baseline and endpoint data) of microbiota profiles, which were constructed via urinary assays of microbe-derived extracellular vesicles, were analyzed and compared between the two groups.</p><p><strong>Results: </strong>Only the intervention group yielded significant results for the Bray-Curtis and Jaccard dissimilarity indices between baseline and endpoint data (<i>P</i> < 0.05). In the phylum-level analysis of microbial composition, the <i>Firmicutes</i> to <i>Bacteroidetes</i> ratio (FB ratio) tended to decrease from baseline in the intervention group; however, it increased in the control group. Differences between the baseline and endpoint FB ratios were significant between the two groups (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>This study's findings suggest that γ-PGA-vitamin B6 supplementation potentially alters the microbial community composition of a host. Further investigation into the biological consequences of commensal microbiota alteration by γ-PGA-containing supplement consumption is warranted.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 5","pages":"663-673"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food-related media use and eating behavior in different food-related lifestyle groups of Korean adolescents in metropolitan areas.","authors":"SooBin Lee, Seoyoung Choi, Se Eun Ahn, Yoon Jung Park, Ji-Yun Hwang, Gaeun Yeo, Jieun Oh","doi":"10.4162/nrp.2024.18.5.687","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.5.687","url":null,"abstract":"<p><strong>Background/objectives: </strong>This study investigated the relationship between adolescent food-related lifestyles and food-related media use and eating behavior in Korea.</p><p><strong>Subjects/methods: </strong>Participants were 392 Korean adolescents, ranging in age from 12 to 18, recruited via convenience sampling. They completed a self-report questionnaire survey consisting of questions about food-related lifestyle, food-related media use, food consumption behavior, food literacy, and nutrition quotient. Data analysis was conducted using SPSS 29.0. (IBM Co., Armonk, NY, USA).</p><p><strong>Results: </strong>The factor analysis of food-related lifestyles identified four factors. Based on the cluster analysis results, participants were classified into three clusters reflecting different levels of interest: high interest in food, moderate interest in food, and low interest in food. The analysis revealed significant differences between groups in food-related liestyle factors (<i>P</i> < 0.05). Notably, the high-interest group demonstrated proactive engagement with food-related content, a willingness to explore diverse culinary experiences, and a conscientious consideration of nutritional labeling during food purchases. In contrast, the low-interest group reported tendencies toward overeating or succumbing to stimulating food consumption post-exposure to food-related content, coupled with a disregard for nutritional labeling when making food choices. A stronger inclination toward a food-related lifestyle was positively correlated with higher levels of food literacy and nutrition quotient.</p><p><strong>Conclusion: </strong>This study proposes that the implementation of a nutrition education program using media could effectively promote a healthy diet among adolescents with a high level of interest in their dietary habits. For adolescents with low interest in their dietary habits, it suggests that introducing an education program with a primary focus on enhancing food literacy could be beneficial in fostering a healthy diet. Our research findings provide insight for the development of tailored nutritional education programs and establishment of effective nutrition policies.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 5","pages":"687-700"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Cladophora glomerata</i> Kützing extract exhibits antioxidant, anti-inflammation, and anti-nitrosative stress against impairment of renal organic anion transport in an <i>in vivo</i> study.","authors":"Atcharaporn Ontawong, Chaliya J Aida, Pornpun Vivithanaporn, Doungporn Amornlerdpison, Chutima S Vaddhanaphuti","doi":"10.4162/nrp.2024.18.5.633","DOIUrl":"https://doi.org/10.4162/nrp.2024.18.5.633","url":null,"abstract":"<p><strong>Background/objectives: </strong><i>Cladophora glomerata</i> extract (CGE), rich in polyphenols, was reported to exhibit antidiabetic and renoprotective effects by modulating the functions of protein kinases-mediated organic anion transporter 1 (Oat1) and 3 (Oat3) in rats with type 2 diabetes mellitus (T2DM). Nevertheless, the antioxidant effects of CGE on such renoprotection have not been investigated. This study examined the mechanisms involved in the antioxidant effects of CGE on renal organic anion transport function in an <i>in vivo</i> study.</p><p><strong>Materials/methods: </strong>Diabetes was induced in the rats through a high-fat diet combined with a single dose of 40 mg/kg body weight (BW) streptozotocin. Subsequently, normal-diet rats were supplemented with a vehicle or 1,000 mg/kg BW of CGE, while T2DM rats were supplemented with a vehicle, CGE, or 200 mg/kg BW of vitamin C for 12 weeks. The study evaluated the general characteristics of T2DM and renal oxidative stress markers. The renal organic transport function was assessed by measuring the para-aminohippurate (PAH) uptake using renal cortical slices and renal inflammatory cytokine expression in the normal diet (ND) and ND + CGE treated groups.</p><p><strong>Results: </strong>CGE supplementation significantly reduced hyperglycemia, hypertriglyceridemia, insulin resistance, and renal lipid peroxidation in T2DM rats. This was accompanied by the normalization of high expressions of renal glutathione peroxidase and nuclear factor kappa B by CGE and vitamin C. The renal anti-inflammation of CGE was evidenced by the reduction of tumor necrosis factor-1α and interleukin-1β. CGE directly blunted sodium nitroprusside-induced renal oxidative/nitrosative stresses and mediated the PAH uptake in the normally treated CGE in rats was particularly noteworthy. These data also correlated with reduced nitric oxide production, highlighting the potential of CGE as a therapeutic agent for managing T2DM-related renal complications.</p><p><strong>Conclusion: </strong>These findings suggest that CGE has antidiabetic effects and directly prevents diabetic nephropathy through oxidative/nitrosative stress pathways.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"18 5","pages":"633-646"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142470991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}