Nutrition Research and Practice最新文献

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Effects of campus dining sustainable practices on consumers' perception and behavioral intention in the United States. 美国校园餐饮可持续实践对消费者感知和行为意向的影响。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-07-17 DOI: 10.4162/nrp.2023.17.5.1019
Borham Yoon, Kyungyul Jun
{"title":"Effects of campus dining sustainable practices on consumers' perception and behavioral intention in the United States.","authors":"Borham Yoon,&nbsp;Kyungyul Jun","doi":"10.4162/nrp.2023.17.5.1019","DOIUrl":"https://doi.org/10.4162/nrp.2023.17.5.1019","url":null,"abstract":"<p><strong>Background/objectives: </strong>Sustainability has become one of the top priorities in the foodservice industry. With an increase in consumer interest in sustainability and educational opportunities in higher education, it is important to know what sustainable practices are implemented in campus dining and how sustainable practices affect consumers' responses. This study aims to identify the key sustainable practices in the campus dining context, and investigate the relationship by applying the stimulus-organism-response framework to determine whether the key sustainable practices influence consumers' perception and behavioral intentions.</p><p><strong>Subjects/methods: </strong>The self-administered online survey was distributed to college students in 8 dining halls at a large southeastern university in the United States from September 20-October 10, 2019. A total of 382 valid questionnaires were collected, and factor analysis and multiple regressions were utilized to test the research model.</p><p><strong>Results: </strong>This study identified 4 dimensions of campus sustainability with a total of sustainable practices: sustainable food, waste management, energy/water conservation, and recycling/reuse. Three dimensions of sustainable campus practices (i.e., sustainable food, waste management, recycling/reuse) played a significant role in consumers forming a perceived value while energy/water conservation did not significantly influence the consumers' perceived value toward the campus dining. Waste management was identified as the most important practice to enhance consumers' perceived value (β = 0.330). Using sustainable food and recycling/reuse were ranked second and third, respectively (β = 0.262, β = 0.154). The findings confirmed the significant positive relationship between perceived value and revisit intentions.</p><p><strong>Conclusions: </strong>The findings support the inclusion of dining sustainability as a critical component in explaining college students' perceived value and revisit intention toward campus dining. Furthermore, this study provides practical implications for university administrators and foodservice operators to consider the key sustainable practices to meet the consumers' value and revisit intentions.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"1019-1027"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/1f/nrp-17-1019.PMC10522818.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41101465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of dietary vitamin A and C intake with asthma, allergic rhinitis, and allergic respiratory diseases. 饮食中维生素A和C的摄入与哮喘、过敏性鼻炎和过敏性呼吸道疾病的关系。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-08-21 DOI: 10.4162/nrp.2023.17.5.997
Carolina García-García, Minju Kim, Inkyung Baik
{"title":"Associations of dietary vitamin A and C intake with asthma, allergic rhinitis, and allergic respiratory diseases.","authors":"Carolina García-García,&nbsp;Minju Kim,&nbsp;Inkyung Baik","doi":"10.4162/nrp.2023.17.5.997","DOIUrl":"https://doi.org/10.4162/nrp.2023.17.5.997","url":null,"abstract":"<p><strong>Background/objectives: </strong>Asthma and allergic rhinitis (AR) are closely related and considered as allergic respiratory diseases (ARD), and their prevalence has recently increased. Data on the association of dietary antioxidant vitamin intake with asthma and AR in adults are limited. The present study aimed to investigate the associations of vitamin A and C intake with asthma, AR, and all cases of both diseases in young adults who participated in a cross-sectional national survey, with the use of high-sensitivity C-reactive protein (hs-CRP) level as an effect modifier.</p><p><strong>Subjects/methods: </strong>This study included 6,293 male and female adults aged 20-49 years from the Korea National Health and Nutrition Examination Survey (KNHANES) conducted between 2016 and 2018. The questionnaire-based reports on asthma and AR diagnosis were used to determine outcome variables. Further, 24-h recall data on dietary vitamin A and C, carotene, and retinol intake were acquired. Logistic regression analysis was performed to calculate odds ratios (ORs) and 95% confidence interval (CI).</p><p><strong>Results: </strong>Dietary vitamin C intake was inversely associated with asthma prevalence among participants with hs-CRP levels (≥ 1 mg/L); the OR of asthma prevalence was 0.27 (95% CI, 0.08-0.84) for participants with vitamin C consumption ≥ 75 mg/day compared with those consuming < 20 mg/day. Similar association analyses limiting to non-users of dietary supplements were performed to rule out the potential effects of supplement intake on the outcomes; results showed a stronger association. However, the association between vitamin C and asthma was not significant in participants with hs-CRP levels < 1 mg/L; the OR of asthma was 1.44 (95% CI, 0.66-3.16) for participants with vitamin C consumption ≥ 75 mg/day compared with those consuming < 20 mg/day. Vitamin C intake was not associated with AR. Moreover, there was no association between vitamin A intake and neither asthma nor AR.</p><p><strong>Conclusions: </strong>These findings suggest that higher vitamin C intake may play a potential role in reducing asthma prevalence. Nevertheless, further studies should be conducted to evaluate whether this association is causal.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"997-1006"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/50/nrp-17-997.PMC10522813.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41136587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between plant protein intake and grip strength in Koreans aged 50 years or older: Korea National Health and Nutrition Examination Survey 2016-2018. 50岁及以上韩国人的植物蛋白摄入量与握力之间的关系:2016-2018年韩国国家健康和营养检查调查。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-07-12 DOI: 10.4162/nrp.2023.17.5.969
Sook-Hyun Jun, Jung Woo Lee, Woo-Kyoung Shin, Seung-Yeon Lee, Yookyung Kim
{"title":"Association between plant protein intake and grip strength in Koreans aged 50 years or older: Korea National Health and Nutrition Examination Survey 2016-2018.","authors":"Sook-Hyun Jun,&nbsp;Jung Woo Lee,&nbsp;Woo-Kyoung Shin,&nbsp;Seung-Yeon Lee,&nbsp;Yookyung Kim","doi":"10.4162/nrp.2023.17.5.969","DOIUrl":"10.4162/nrp.2023.17.5.969","url":null,"abstract":"<p><strong>Background/objectives: </strong>We investigated the association of plant and animal protein intake with grip strength in Koreans aged ≥ 50 yrs.</p><p><strong>Subjects/methods: </strong>The data was collected from 3,610 men and 4,691 women (≥ 50 yrs) from the 2016-2018 Korea National Health and Nutrition Examination Survey. We calculated the total energy intake, and the intake of animal and plant protein and collected dietary data using 1-day 24-h dietary recalls. Low grip strength (LGS) was defined as the lowest quintile (men: up to 26.8 kg, women: up to 15.7 kg). The association of protein intake with grip strength was examined using Pearson's correlation and multiple linear regression analysis.</p><p><strong>Results: </strong>The results proved that participants with LGS had lower daily energy, protein and fat intake, and percent energy from protein than those with normal or high grip strength (<i>P</i> < 0.0001). Total energy intake, animal protein, and plant protein were positively associated with grip strength. A higher intake of total plant protein (<i>P</i> for trend = 0.004 for men, 0.05 for women) and legumes, nuts, and seeds (LNS) protein (<i>P</i> for trend = 0.01 for men, 0.02 for women) was significantly associated with a lower prevalence of LGS. However, non-LNS plant protein intake was not associated with LGS (<i>P</i> for trend = 0.10 for men, 0.15 for women). In women, a higher total animal protein intake was significantly associated with decreased LGS (<i>P</i> for trend = 0.03).</p><p><strong>Conclusions: </strong>Higher total plant protein and LNS protein intake are negatively associated with LGS.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"969-983"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/66/nrp-17-969.PMC10522807.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41158341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender differences in the association between food costs and obesity in Korean adults: an analysis of a population-based cohort. 韩国成年人食物成本与肥胖相关性的性别差异:基于人群的队列分析。
IF 2 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-08-22 DOI: 10.4162/nrp.2023.17.5.984
Soim Park, Jihye Kim
{"title":"Gender differences in the association between food costs and obesity in Korean adults: an analysis of a population-based cohort.","authors":"Soim Park, Jihye Kim","doi":"10.4162/nrp.2023.17.5.984","DOIUrl":"10.4162/nrp.2023.17.5.984","url":null,"abstract":"<p><strong>Background/objectives: </strong>Prior studies, mostly conducted in Western countries, have suggested that the low cost of energy-dense foods is associated with an increased risk of obesity. This study aimed to investigate the association between food costs and obesity risk among Koreans who may have different food cost and dietary patterns than those of Western populations.</p><p><strong>Subjects/methods: </strong>We used baseline data from a cohort of 45,193 men and 83,172 women aged 40-79 years (in 2006-2013). Dietary intake information was collected using a validated food frequency questionnaire. Prudent and Western dietary patterns extracted via principal component analysis. Food cost was calculated based on Korean government data and market prices. Logistic regression analyses were performed to investigate the association of daily total, prudent, and Western food cost per calorie with obesity.</p><p><strong>Results: </strong>Men in the highest total food cost quintile had 15% higher odds of obesity, after adjusting for demographic characteristics and lifestyle factors (adjusted odds ratio, 1.15; 95% confidence interval, 1.08-1.22; <i>P</i>-trend < 0.001); however, this association was not clear in women (<i>P</i>-trend = 0.765). While both men and women showed positive associations between prudent food cost and obesity (<i>P</i>-trends < 0.001), the association between Western food cost and obesity was only significant in men (<i>P</i>-trend < 0.001).</p><p><strong>Conclusions: </strong>In countries in which consumption of Western foods is associated with higher food costs, higher food costs are associated with an increased risk of obesity; however, this association differs between men and women.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"984-996"},"PeriodicalIF":2.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4a/95/nrp-17-984.PMC10522812.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41124798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective effect of Lycium barbarum leaf extracts on atopic dermatitis: in vitro and in vivo studies. 枸杞叶提取物对特应性皮炎的保护作用:体外和体内研究。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-07-11 DOI: 10.4162/nrp.2023.17.5.855
Han Sol Lee, Eun Young Bae, Sun Yung Ly
{"title":"Protective effect of <i>Lycium barbarum</i> leaf extracts on atopic dermatitis: <i>in vitro</i> and <i>in vivo</i> studies.","authors":"Han Sol Lee,&nbsp;Eun Young Bae,&nbsp;Sun Yung Ly","doi":"10.4162/nrp.2023.17.5.855","DOIUrl":"https://doi.org/10.4162/nrp.2023.17.5.855","url":null,"abstract":"<p><strong>Background/objectives: </strong>Atopic dermatitis (AD) is a chronic disease with an increasing incidence globally; therefore, there is a growing demand for natural compounds effective in treating dermatitis. In this study, the protective effects of <i>Lycium barbarum</i> leaves with and without chlorophyll (LLE and LLE[Ch-]) on AD were investigated in animal models of AD and HaCaT cells. Further, we investigated whether LLE and LLE(Ch-) show any differences in physiological activity.</p><p><strong>Materials/methods: </strong>AD was induced by 2,4-dinitrochlorobenzene (DNCB) for three weeks, while NC/Nga mice were fed LLE or LLE(Ch-) extracts for 7 weeks. Serum immunoglobulin E (IgE) and cytokine (tumor necrosis factor [TNF]-α, interleukin [IL]-6, and IL-4) concentrations and the degree of DNA fragmentation in lymphocytes were examined. A histopathological examination (haematoxylin & eosin staining and blue spots of toluidine) of the dorsal skin of mice was performed. To elucidate the mechanism of action, the expression of the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) were measured in HaCaT cells.</p><p><strong>Results: </strong>Serum IgE and cytokines (TNF-α and IL-6) levels as well as DNA fragmentation of lymphocytes were significantly decreased in AD-induced mice treated with LLE or LLE(Ch-) compared to those of the control group. The epidermal thickness of the dorsal skin and mast cell infiltration in the LLE group significantly reduced compared to that in the control group. The LLE extracts showed no cytotoxicity up to 1,000 µg/mL in HaCaT cells. LLE or LLE(Ch-)-treated group showed a reduction of TARC and MDC in TNF-α-and IFN-γ-stimulated HaCaT cells.</p><p><strong>Conclusions: </strong>These results suggest that LLE potentially improves inflammation by reducing the expression of chemokines that inhibit T helper 2 cell migration. LLE(Ch-) showed similar effects to LLE on blood levels of IgE, TNF-α and IL-6 and protein expression in HaCat cells, but the ultimate effect of skin improvement was not statistically significant. Therefore, both LLE and LLE(Ch-) can be used as functional materials to alleviate AD, but LLE(Ch-) appears to require more research to improve inflammation.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"855-869"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d7/f8/nrp-17-855.PMC10522814.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41155029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newly developed care food enhances grip strength in older adults with dysphagia: a preliminary study. 一项初步研究表明,新开发的护理食品可增强老年吞咽困难患者的握力。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-07-18 DOI: 10.4162/nrp.2023.17.5.934
Hyejin Han, Yoonhee Park, Hyeji Kwon, Yeseung Jeong, Soyoung Joo, Mi Sook Cho, Ju Yeon Park, Hee-Won Jung, Yuri Kim
{"title":"Newly developed care food enhances grip strength in older adults with dysphagia: a preliminary study.","authors":"Hyejin Han,&nbsp;Yoonhee Park,&nbsp;Hyeji Kwon,&nbsp;Yeseung Jeong,&nbsp;Soyoung Joo,&nbsp;Mi Sook Cho,&nbsp;Ju Yeon Park,&nbsp;Hee-Won Jung,&nbsp;Yuri Kim","doi":"10.4162/nrp.2023.17.5.934","DOIUrl":"https://doi.org/10.4162/nrp.2023.17.5.934","url":null,"abstract":"<p><strong>Background/objectives: </strong>Maintaining total muscle mass in the older adults with swallowing difficulty (dysphagia) is important for preserving swallowing function. Increasing protein intake can help sustain lean body mass in the older adults. The aim of this study was to evaluate the effect of various high-protein texture-modified foods (HPTMFs) on muscle mass and perform dietary assessment in ≥ 65-yrs-old patients with dysphagia.</p><p><strong>Subjects/methods: </strong>Participants (n = 10) received the newly developed HPTMFs (average 595.23 ± 66.75 kcal/day of energy, 54.22 ± 6.32 g/day of protein) for 10 days. Relative hand-grip strength (RHS), mid-upper arm circumference (MUAC), body composition, mini nutritional assessment (MNA), mini dietary assessment (MDA), and Euro Quality-of-Life questionnaire 5-dimensional classification (EQ-5D) were assessed.</p><p><strong>Results: </strong>After 10 days, an increase in MUAC (26.36 ± 2.35 cm to 28.50 ± 3.17 cm, <i>P</i> = 0.013) and RHS (0.38 ± 0.24 kg/kg body weight to 0.42 ± 0.22 kg/kg body weight, <i>P</i> = 0.046) was observed. Although MNA, MDA, EQ-5D, subjective health status, muscle mass, and calf circumference showed a tendency to increase after intervention, no significant differences were found.</p><p><strong>Conclusions: </strong>These results suggest that the HPTMFs can be used for improving the nutritional and health status in patients with dysphagia.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"934-944"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bd/47/nrp-17-934.PMC10522817.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41146670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Pogonatherum paniceum (Lamk) Hack extract on anti-mitochondrial DNA mediated inflammation by attenuating Tlr9 expression in LPS-induced macrophages. 穗黄精提取物通过减弱LPS诱导的巨噬细胞中Tlr9的表达对抗线粒体DNA介导的炎症的影响。
IF 2 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-05-26 DOI: 10.4162/nrp.2023.17.5.827
Rungthip Thongboontho, Kanoktip Petcharat, Narongsuk Munkong, Chakkraphong Khonthun, Atirada Boondech, Kanokkarn Phromnoi, Arthid Thim-Uam
{"title":"Effects of <i>Pogonatherum paniceum</i> (Lamk) Hack extract on anti-mitochondrial DNA mediated inflammation by attenuating <i>Tlr9</i> expression in LPS-induced macrophages.","authors":"Rungthip Thongboontho, Kanoktip Petcharat, Narongsuk Munkong, Chakkraphong Khonthun, Atirada Boondech, Kanokkarn Phromnoi, Arthid Thim-Uam","doi":"10.4162/nrp.2023.17.5.827","DOIUrl":"10.4162/nrp.2023.17.5.827","url":null,"abstract":"<p><strong>Background/objectives: </strong>Mitochondrial DNA leakage leads to inflammatory responses via endosome activation. This study aims to evaluate whether the perennial grass water extract (<i>Pogonatherum panicum</i>) ameliorate mitochondrial DNA (mtDNA) leakage.</p><p><strong>Materials/methods: </strong>The major bioactive constituents of <i>P. paniceum</i> (PPW) were investigated by high-performance liquid chromatography, after which their antioxidant activities were assessed. In addition, RAW 264.7 macrophages were stimulated with lipopolysaccharide, resulting in mitochondrial damage. Quantitative polymerase chain reaction and enzyme-linked immunosorbent assay were used to examine the gene expression and cytokines.</p><p><strong>Results: </strong>Our results showed that PPW extract-treated activated cells significantly decrease reactive oxygen species and nitric oxide levels by reducing the <i>p22<sup>phox</sup></i> and <i>iNOS</i> expression and lowering cytokine-encoding genes, including <i>IL-6</i>, <i>TNF-α</i>, <i>IL-1β</i>, <i>PG-E2</i> and <i>IFN-γ</i> relative to the lipopolysaccharide (LPS)-activated macrophages. Furthermore, we observed that LPS enhanced the mtDNA leaked into the cytoplasm, increasing the transcription of <i>Tlr9</i> and signaling both <i>MyD88</i>/<i>Irf7-</i>dependent interferon and MyD88/NF-κb p65-dependent inflammatory cytokine mRNA expression but which was alleviated in the presence of PPW extract.</p><p><strong>Conclusions: </strong>Our data show that PPW extract has antioxidant and anti-inflammatory activities by facilitating mtDNA leakage and lowering the <i>Tlr9</i> expression and signaling activation.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"827-843"},"PeriodicalIF":2.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/54/7a/nrp-17-827.PMC10522809.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41109600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peanut sprout tea extract inhibits lung metastasis of 4T1 murine mammary carcinoma cells by suppressing the crosstalk between cancer cells and macrophages in BALB/c mice. 花生芽茶提取物通过抑制BALB/c小鼠中癌症细胞与巨噬细胞之间的串扰来抑制4T1小鼠乳腺癌细胞的肺转移。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-06-23 DOI: 10.4162/nrp.2023.17.5.917
Jae In Jung, Hyun Sook Lee, Jaehak Lee, Eun Ji Kim
{"title":"Peanut sprout tea extract inhibits lung metastasis of 4T1 murine mammary carcinoma cells by suppressing the crosstalk between cancer cells and macrophages in BALB/c mice.","authors":"Jae In Jung,&nbsp;Hyun Sook Lee,&nbsp;Jaehak Lee,&nbsp;Eun Ji Kim","doi":"10.4162/nrp.2023.17.5.917","DOIUrl":"https://doi.org/10.4162/nrp.2023.17.5.917","url":null,"abstract":"<p><strong>Background/objectives: </strong>As peanuts germinate, the content of the components beneficial to health, such as resveratrol, increases within the peanut sprout. This study examined whether the ethanol extract of peanut sprout tea (PSTE) inhibits breast cancer growth and metastasis.</p><p><strong>Materials/methods: </strong>After orthotopically injecting 4T1 cells into BALB/c mice to induce breast cancer, 0, 30, or 60 mg/kg body weight/day of PSTE was administered orally. Angiogenesis-related protein expression in the tumors and the degree of metastasis were analyzed. 4T1 and RAW 264.7 cells were co-cultured, and reverse transcription polymerase chain reaction was performed to measure the crosstalk between breast cancer cells and macrophages.</p><p><strong>Results: </strong>PSTE reduced tumor growth and lung metastasis. In particular, PSTE decreased matrix metalloproteinase-9, platelet endothelial cell adhesion molecule-1, vascular endothelial growth factor-A, F4/80, CD11c, macrophage mannose receptor, macrophage colony-stimulating factor, and monocyte chemoattractant protein 1 expression in the tumors. Moreover, PSTE prevented 4T1 cell migration, invasion, and macrophage activity in RAW 264.7 cells. PSTE inhibited the crosstalk between 4T1 cells and RAW 264.7 cells and promoted the macrophage M1 subtype while inhibiting the M2 subtype.</p><p><strong>Conclusions: </strong>These results suggest that PSTE blocks breast cancer growth and metastasis to the lungs. This may be because the PSTE treatment inhibits the crosstalk between mammary cancer cells and macrophages and inhibits the differentiation of macrophages into the M2 subtype.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"917-933"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/da/nrp-17-917.PMC10522819.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41144664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can tailored home-delivered meal services alleviate self-rated frailty of the low-income older adults in Korea? 量身定制的家庭送餐服务能否缓解韩国低收入老年人自我评估的脆弱性?
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-05-31 DOI: 10.4162/nrp.2023.17.5.1007
Junghyun Kim, Hyeja Chang
{"title":"Can tailored home-delivered meal services alleviate self-rated frailty of the low-income older adults in Korea?","authors":"Junghyun Kim,&nbsp;Hyeja Chang","doi":"10.4162/nrp.2023.17.5.1007","DOIUrl":"https://doi.org/10.4162/nrp.2023.17.5.1007","url":null,"abstract":"<p><strong>Background/objectives: </strong>This study aimed to examine whether the tailored home-delivered meal (HDM) services included nutrition counseling impacts alleviating self-rated frailty among low-income older adults in Korea.</p><p><strong>Subjects/methods: </strong>Pre- and post-test were implemented on May 27 and on November 25 in 2019 during 3 weeks, respectively, before and after the 6 months intervention program. Participants completed a questionnaire measuring frailty, malnutrition, food security, depression, and underlying diseases. Initially, 136 older adults were selected as participants for this study, they were recipients of a free meal program from 2 senior welfare centers in Seoul, the final sample size of those who completed the intervention program was 117 (female 70.9%, male 29.1%). Statistical analyses were conducted with IBM SPSS package program, paired <i>t</i>-test and χ<sup>2</sup> test to validate the test.</p><p><strong>Results: </strong>There were statistically significant differences in the score of the Tilburg Frailty Indicator (TFI) before and after receiving the tailored HDM services (pre-test 9.46, post-test 2.8, <i>P</i> < 0.01). The differences in the score of TFI by 3 risk groups at the pre-test decreased as a result of receiving these services.</p><p><strong>Conclusions: </strong>The tailored HDM services alleviated the self-rated frailty of low-income older adults with limited mobility in a community setting. Based on the positive outcomes this study could be applied to developing social services for aging in place.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"1007-1018"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d0/ec/nrp-17-1007.PMC10522816.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41105325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between diet quality and untreated dental caries: results from the Korea National Health and Nutrition Examination Survey. 饮食质量与未经治疗的龋齿之间的关系:韩国国家健康和营养检查调查的结果。
IF 2.4 4区 医学
Nutrition Research and Practice Pub Date : 2023-10-01 Epub Date: 2023-07-06 DOI: 10.4162/nrp.2023.17.5.959
Seon-Ju Sim, Ja-Young Moon, Hye-Sun Shin
{"title":"Association between diet quality and untreated dental caries: results from the Korea National Health and Nutrition Examination Survey.","authors":"Seon-Ju Sim,&nbsp;Ja-Young Moon,&nbsp;Hye-Sun Shin","doi":"10.4162/nrp.2023.17.5.959","DOIUrl":"https://doi.org/10.4162/nrp.2023.17.5.959","url":null,"abstract":"<p><strong>Background/objectives: </strong>Few studies have provided evidence of the association between diet quality and dental caries. This study aimed to examine the association between diet quality and untreated dental caries in a Korean representative population.</p><p><strong>Subjects/methods: </strong>The study population included a sample of 13,815 participants, aged ≥ 19 from the Korea National Health and Nutrition Examination Survey during 2013-2015. The explanatory variable was diet quality and the outcome variable was untreated dental caries. Untreated dental caries were defined by the number of decayed teeth recorded according to the criteria established by the World Health Organization. Diet quality was defined by using the Korean Healthy Eating Index (KHEI) through the 24-h recall methods. We assessed the association between diet quality and untreated dental caries while adjusting for age, sex, education, income, smoking status, dental visits, toothbrushing frequencies, obesity, and diabetes mellitus.</p><p><strong>Results: </strong>The mean overall KHEI scores in the untreated dental caries group were significantly lower than those in the group without untreated dental caries. Significant differences were observed in the untreated dental caries group based on the KHEI quartiles (<i>P</i> < 0.001). After adjusting for potential confounders, the quartiles of KHEI scores showed an association with untreated dental caries, demonstrating a dose-effect trend (odds ratio [OR], 1.57; 95% confidence interval [CI], 1.35-1.84 for 1st quartile; OR, 1.38; 95% CI, 1.19-1.59 for 2nd quartile; OR, 1.32; 95% CI, 1.14-1.53 for 3rd quartile; reference quartile highest]).</p><p><strong>Conclusions: </strong>The findings indicated an inverse association between diet quality and untreated dental caries in Korean adults. Healthcare providers should take into account the significant role of diet quality in preventing and managing oral health.</p>","PeriodicalId":19232,"journal":{"name":"Nutrition Research and Practice","volume":"17 5","pages":"959-968"},"PeriodicalIF":2.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/13/nrp-17-959.PMC10522811.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41142709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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