Journal of Biophotonics最新文献_第2页

Neuronal Imaging at 8-Bit Depth to Combine High Spatial and High Temporal Resolution With Acquisition Rates Up To 40 kHz 神经元成像在8位深度结合高空间和高时间分辨率与采集率高达40 kHz。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-10 DOI: 10.1002/jbio.202400513

Fatima Abbas, Ömer Yusuf İpek, Philippe Moreau, Marco Canepari

引用次数: 0

Ion-Regulated Signal Amplification Optical Microfiber Interferometric DNA Sensor 离子调节信号放大光学微光纤干涉DNA传感器。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-07 DOI: 10.1002/jbio.202400389

Hanglin Lu, Li Yang, Yuanpeng Li, Jian Tang, Laipeng Shao, Kepeng Fu, Jinpeng Wei, Yalan Niu, Juihui Hu

{"title":"Ion-Regulated Signal Amplification Optical Microfiber Interferometric DNA Sensor","authors":"Hanglin Lu, Li Yang, Yuanpeng Li, Jian Tang, Laipeng Shao, Kepeng Fu, Jinpeng Wei, Yalan Niu, Juihui Hu","doi":"10.1002/jbio.202400389","DOIUrl":"10.1002/jbio.202400389","url":null,"abstract":"<div>\u0000 \u0000 <p>Genetic information sensors play a pivotal role in the biomedical field. The detection of deoxyribonucleic acid (DNA) is achieved experimentally using an optical microfiber interferometric sensor, which operates based on an ion-regulation sensitivity enhancement mechanism. The optical microfiber is fabricated by drawing optical fiber into a diameter of less than 10 μm via the melting and tapering technique. Leveraging the characteristics of monovalent cations can effectively promote the folding of G-rich single-stranded DNA (ssDNA) into stable G-quadruplex structures, enabling the detection of specific sequences of ssDNA at low concentrations. The results show an improvement of the linear detection range by 3 orders of magnitude, and with the introduction of the ion-regulation sensitivity enhancement mechanism, the limit of detection (LOD) value is 1.07 × 10<sup>−15</sup> M. This optical microfiber interferometric sensing architecture is characterized by its simplicity and high sensitivity, positioning it as a formidable tool for diverse biosensing and analytical applications.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mueller-Matrix Interferometric Multifractal Scaling of Optically Anisotropic Architectonics of Diffuse Blood Facies: Fundamental and Applied Aspects 弥漫性血相光学各向异性结构的mueller -矩阵干涉多重分形标度：基础与应用

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2025-01-06 DOI: 10.1002/jbio.202400412

Yurii Ushenko, Alexander Ushenko, Alexander Dubolazov, Iryna Soltys, Olexandra Litvinenko, Oleh Wanchuliak, Yulia Sarkisova, Ivan Mikirin, Olexander Salega, Jun Zheng, Lin Bin

{"title":"Mueller-Matrix Interferometric Multifractal Scaling of Optically Anisotropic Architectonics of Diffuse Blood Facies: Fundamental and Applied Aspects","authors":"Yurii Ushenko, Alexander Ushenko, Alexander Dubolazov, Iryna Soltys, Olexandra Litvinenko, Oleh Wanchuliak, Yulia Sarkisova, Ivan Mikirin, Olexander Salega, Jun Zheng, Lin Bin","doi":"10.1002/jbio.202400412","DOIUrl":"10.1002/jbio.202400412","url":null,"abstract":"<div>\u0000 \u0000 <p>The article describes a technique for digital holographic reconstruction of complex amplitude fields in diffuse blood facies using laser polarization-interference phase scanning to isolate a single scattered component of the object field. This method serves as the basis for developing algorithms for Mueller-matrix reconstruction of linear and circular birefringence parameters in the polycrystalline architectonics of blood facies. Statistical (central moments of the 1st–4th orders) and multifractal analyses (fractal dimension spectra) are applied to study the optical anisotropy maps of polycrystalline networks during blood dehydration. The study explores a practical application in the differential diagnosis of blood loss volume, identifying higher-order central moments (skewness, kurtosis) as sensitive markers. The method achieved a maximum accuracy of 92.9% in differentiating blood loss volume.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integration of Optical Coherence Tomography Images and Real-Life Clinical Data for Deep Learning Modeling: A Unified Approach in Prognostication of Diabetic Macular Edema 整合光学相干断层扫描图像和真实临床数据的深度学习建模：糖尿病黄斑水肿预后的统一方法。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-29 DOI: 10.1002/jbio.202400315

Muhammed Enes Atik, İbrahim Kocak, Nihat Sayin, Sadik Etka Bayramoglu, Ahmet Ozyigit

{"title":"Integration of Optical Coherence Tomography Images and Real-Life Clinical Data for Deep Learning Modeling: A Unified Approach in Prognostication of Diabetic Macular Edema","authors":"Muhammed Enes Atik, İbrahim Kocak, Nihat Sayin, Sadik Etka Bayramoglu, Ahmet Ozyigit","doi":"10.1002/jbio.202400315","DOIUrl":"10.1002/jbio.202400315","url":null,"abstract":"<div>\u0000 \u0000 <p>The primary ocular effect of diabetes is diabetic retinopathy (DR), which is associated with diabetic microangiopathy. Diabetic macular edema (DME) can cause vision loss for people with DR. For this reason, deciding on the appropriate treatment and follow-up has a critical role in terms of curing the disease. Current artificial intelligence (AI) approaches focus on OCT images and may ignore clinical, laboratory, and demographic information obtained by the specialist. This study presents a novel deep learning (DL) framework for evaluating the visual outcome of the TREX anti-VEGF intravitreal injection regimen. DL models are trained to extract deep features from OCT and ILM topographic images and the obtained deep features are combined with patients' demographic, clinical, and laboratory findings to predict the direction of the treatment process. When the ResNet-18 network is used, the proposed DL framework is able to predict the prognosis status of patients with the highest accuracy.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142908033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polarization Imaging Method for Detection of Lung Cancer Based on Symmetrical Single LCVR

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-29 DOI: 10.1002/jbio.202400470

Yuan Song, Danfei Huang, Tianyi Wang, Yi Xie, Dong Song, Jinghui Hong, Yushi Yang, Jiaxuan Yan

引用次数: 0

Prototype of Implant for Nitric Oxide Release Controlled by Infrared Radiation in Therapeutic Window 在治疗窗口通过红外线辐射控制一氧化氮释放的植入物原型。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-25 DOI: 10.1002/jbio.202400455

Natalia A. Virts, Tatyana Yu. Karogodina, Mikhail A. Panfilov, Alexey Yu. Vorob'ev, Alexander E. Moskalensky

{"title":"Prototype of Implant for Nitric Oxide Release Controlled by Infrared Radiation in Therapeutic Window","authors":"Natalia A. Virts, Tatyana Yu. Karogodina, Mikhail A. Panfilov, Alexey Yu. Vorob'ev, Alexander E. Moskalensky","doi":"10.1002/jbio.202400455","DOIUrl":"10.1002/jbio.202400455","url":null,"abstract":"<div>\u0000 \u0000 <p>Local therapeutic action and targeted drug release are promising approaches compared to traditional systemic drug administration. This is especially relevant for nitric oxide (NO), as its effects change dramatically depending on concentration and cellular context. Materials capable of releasing NO in deep tissues in a controlled manner might open new therapeutic opportunities. Light-sensitive NO donors represent a fascinating class of compounds with significant potential for precise and controlled NO release. However, most of them are sensitive to visible light, with only a few examples absorbing in a near-infrared therapeutic window. Here, we present the proof-of-concept of soft implants consisting of the photon upconverting core and the outer shell loaded with visible-light triggered NO donor. The separation into two compartments results in efficient energy harvesting by the dye and effective NO release under 980 nm infrared irradiation. Such implants could be used in smart therapies implying well-controlled and localized NO release.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Validation of a Multimodal Diffuse Reflectance and Spatially Offset Raman Spectroscopy System for In Vivo Applications 体内应用的多模态漫反射和空间偏移拉曼光谱系统的设计和验证。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-25 DOI: 10.1002/jbio.202400333

April Mordi, Varsha Karunakaran, Umme Marium Mim, Eric Marple, Narasimhan Rajaram

{"title":"Design and Validation of a Multimodal Diffuse Reflectance and Spatially Offset Raman Spectroscopy System for In Vivo Applications","authors":"April Mordi, Varsha Karunakaran, Umme Marium Mim, Eric Marple, Narasimhan Rajaram","doi":"10.1002/jbio.202400333","DOIUrl":"10.1002/jbio.202400333","url":null,"abstract":"<p>We report on the development of a multimodal spectroscopy system, combining diffuse reflectance spectroscopy (DRS) and spatially offset Raman spectroscopy (SORS). A fiber optic probe was designed with spatially offset source–detector fibers to collect subsurface measurements for each modality, as well as ball lens-coupled fibers for superficial measurements. The system acquires DRS, zero-offset Raman spectroscopy (RS) and SORS with good signal-to-noise ratio. Measurements on chicken breast tissue demonstrate that both DRS and RS can acquire spectra from similar depths within tissue. Measurements acquired from the skin of a human volunteer demonstrate distinct Raman peaks at 937 and 1755 cm<sup>−1</sup> that were unique to the zero-offset ball lens configuration and 718 and 1089 cm<sup>−1</sup> for the spatially offset setting. We also identified Raman peaks corresponding to melanin that were prominent in the superficial measurements obtained with the ball lens-coupled fibers but not in the spatially offset fibers.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silicone Loss During Histological Preparation of Breast Implant Tissue From Capsular Contracture, Quantified by Stimulated Raman Scattering Microscopy 用受激拉曼散射显微镜定量观察乳房假体包膜挛缩在组织制备过程中的硅酮损失。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-23 DOI: 10.1002/jbio.202400415

Robert W. Schmidt, Erik de Bakker, Freek Ariese

引用次数: 0

Tailored Functionalization of Plasmonic AgNPs/C:H:N:O Nanocomposite for Sensitive and Selective Detection 等离子体AgNPs/C:H:N:O纳米复合材料的定制功能化敏感和选择性检测。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-23 DOI: 10.1002/jbio.202400353

Sanjay Kumar, Hana Maskova, Anna Kuzminova, Paval Curda, Lenka Doudova, Jan Sterba, Ondřej Kylián, Ryan O. M. Rego, Vítězslav Straňák

{"title":"Tailored Functionalization of Plasmonic AgNPs/C:H:N:O Nanocomposite for Sensitive and Selective Detection","authors":"Sanjay Kumar, Hana Maskova, Anna Kuzminova, Paval Curda, Lenka Doudova, Jan Sterba, Ondřej Kylián, Ryan O. M. Rego, Vítězslav Straňák","doi":"10.1002/jbio.202400353","DOIUrl":"10.1002/jbio.202400353","url":null,"abstract":"<p>We report here on the development of tailored plasmonic AgNPs/C:H:N:O plasma polymer nanocomposites for the detection of the pathogenic bacterium \u0000 <i>Borrelia afzelii</i>\u0000 , with high selectivity and sensitivity. Silver (Ag) nanoparticles, generated by a gas aggregation source, are incorporated onto a C:H:N:O plasma polymer matrix, which is deposited by magnetron sputtering of a nylon 6.6. These anchored Ag nanoparticles propagate localized surface plasmon resonance (LSPR), optically responding to changes caused by immobilized pathogens near the nanoparticles. The tailored functionalization of AgNPs/C:H:N:O nanocomposite surface allows both high selectivity for the pathogen and high sensitivity with an LSPR red-shift Δλ > (4.20 ± 0.71) nm for 50 Borrelia per area 0.785 cm<sup>2</sup>. The results confirmed the ability of LSPR modulation for the rapid and early detection of (not only) tested pathogens.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400353","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Augmented Reality Visor for Intraoperative Visualization, Guidance, and Temperature Monitoring Using Fluorescence 一种用于术中可视化、引导和荧光温度监测的增强现实遮阳板。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-12-23 DOI: 10.1002/jbio.202400417

Oscar Cipolato, Matthias Fauconneau, Paige J. LeValley, Robert Nißler, Benjamin Suter, Inge K. Herrmann

{"title":"An Augmented Reality Visor for Intraoperative Visualization, Guidance, and Temperature Monitoring Using Fluorescence","authors":"Oscar Cipolato, Matthias Fauconneau, Paige J. LeValley, Robert Nißler, Benjamin Suter, Inge K. Herrmann","doi":"10.1002/jbio.202400417","DOIUrl":"10.1002/jbio.202400417","url":null,"abstract":"<p>Fluorescence-guided surgeries, including tumor resection and tissue soldering, are advancing the frontiers of surgical precision by offering enhanced control that minimizes tissue damage, improving recovery and outcomes. However, integrating fluorescence visualization with real-time temperature monitoring remains a challenge, limiting broader clinical use. We address this issue with an augmented reality (AR) visor that combines nanomaterial excitation, fluorescence detection, and temperature monitoring. Using advanced fluorescent nanoparticles like indocyanine green-doped particles and carbon nanotubes, the visor provides a comprehensive view of both the surgical field and sub-surface conditions invisible to the naked eye. This integration improves the safety and efficacy of fluorescence-guided surgeries, including laser tissue soldering, by ensuring optimal temperatures and laser guidance in real time. The presented technology enhances existing surgical techniques and supports the development of new strategies and sensing technologies in areas where traditional methods fall short, marking significant progress in precision surgery and potentially improving patient care.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400417","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0