Journal of Biophotonics最新文献

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Laser-Induced Minimization of Circulating Tumor Cells to Suppress Tumor Metastasis 激光诱导最小化循环肿瘤细胞抑制肿瘤转移。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-02-05 DOI: 10.1002/jbio.202400569
Da Sun, Bingchen Yu, Rui Xu, Chenzheng Wang, Kai Pang
{"title":"Laser-Induced Minimization of Circulating Tumor Cells to Suppress Tumor Metastasis","authors":"Da Sun,&nbsp;Bingchen Yu,&nbsp;Rui Xu,&nbsp;Chenzheng Wang,&nbsp;Kai Pang","doi":"10.1002/jbio.202400569","DOIUrl":"10.1002/jbio.202400569","url":null,"abstract":"<div>\u0000 \u0000 <p>Circulating tumor cells (CTCs) are key indicators of tumor metastasis. Effective clearance of CTCs can reduce the probability of metastasis. We designed a system for the real-time dynamic monitoring and clearance of CTCs, capable of monitoring and clearing CTCs in the living circulatory system. Experimental results showed that pulsed laser treatment significantly affects the clearance of melanoma CTCs. Through in vivo imaging of small animals and survival analysis of mice, we observed that CTC clearance could reduce the size of distant metastatic lesions and prolong the lifespan of the mice. Additionally, we set up a hemolysis experiment to demonstrate that the laser energy used does not cause damage to red blood cells. This study is based on the physical and mechanical destruction of CTCs, meaning there is no issue of drug resistance. This provides a novel approach and technical means for suppressing tumor metastasis and extending the lifespan of patients in clinical settings.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fast In Vivo Two-Photon Fluorescence Imaging via Lateral and Axial Resolution Restoration With Self-Supervised Learning 快速体内双光子荧光成像通过横向和轴向分辨率恢复与自监督学习。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-02-05 DOI: 10.1002/jbio.202400489
Zhengyuan Pan, Man Lei, Hongen Liao, Bobo Gu
{"title":"Fast In Vivo Two-Photon Fluorescence Imaging via Lateral and Axial Resolution Restoration With Self-Supervised Learning","authors":"Zhengyuan Pan,&nbsp;Man Lei,&nbsp;Hongen Liao,&nbsp;Bobo Gu","doi":"10.1002/jbio.202400489","DOIUrl":"10.1002/jbio.202400489","url":null,"abstract":"<div>\u0000 \u0000 <p>Two-photon fluorescence (TPF) imaging opens a new avenue to achieve high resolution at extended penetration depths. However, it is difficult for conventional TPF imaging systems to simultaneously achieve high resolution and speed. In this work, we develop an innovative deep learning framework of Lateral and Axial Resolution Restoration (LARR) to break the contradiction between imaging resolution and speed. LARR employs a self-supervised training scheme to computationally restore the sparsely sampled TPF images to resolution isotropic images by 4-fold axial and 16-fold lateral resolution enhancement. The simulation studies and experimental results demonstrate the excellent performance of LARR to preserve fine structural features with improved signal-to-noise ratio and structure similarity index. Moreover, the TPF imaging system with the LARR is able to achieve 60-fold improved imaging speed and comparable resolution as compared with the conventional TPF system. The outstanding performance makes LARR a potential tool for fast TPF imaging with high resolution.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Compact Prism-Based Microscope for Highly Sensitive Measurements in Fluid Biopsy 一种紧凑的棱镜显微镜,用于液体活检的高灵敏度测量。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-02-05 DOI: 10.1002/jbio.202400519
Laura Perego, Caterina Dallari, Chiara Falciani, Alessandro Pini, Lucia Gardini, Caterina Credi, Francesco Saverio Pavone
{"title":"A Compact Prism-Based Microscope for Highly Sensitive Measurements in Fluid Biopsy","authors":"Laura Perego,&nbsp;Caterina Dallari,&nbsp;Chiara Falciani,&nbsp;Alessandro Pini,&nbsp;Lucia Gardini,&nbsp;Caterina Credi,&nbsp;Francesco Saverio Pavone","doi":"10.1002/jbio.202400519","DOIUrl":"10.1002/jbio.202400519","url":null,"abstract":"<p>The increasing demand for sensitive, portable, and affordable disease detection methods has spurred the development of advanced biosensors for rapid early-stage diagnosis, population mass screening, and bed-monitoring. Current high-sensitivity devices face hurdles such as high production costs and challenges in multiplexed signal detection. To address these, we developed a prism-based total internal reflection system which, in combination with surface functionalization techniques of gold nanoparticles, enables evanescent wave scattering for highly sensitive and rapid detection of specific analytes in both synthetic and human liquid samples. To validate its efficacy, we conducted scattering experiments in synthetic and human serum samples, exploiting functionalized AuNPs to recognize bacterial lipopolysaccharides as biomarkers for sepsis disease. We demonstrate a remarkable sensitivity in the femtogram per mL concentration range for this specific pathological biomarker. Based on this result we envisage the potential adoption of our technique for liquid biopsy in the clinical scenario.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400519","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction of Non-Uniform Rotational Distortion in the Proximally Controlled Endoscopic OCTA 近端控制内镜OCTA非均匀旋转畸变的校正。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-02-04 DOI: 10.1002/jbio.202400467
Zehua Guan, Qiang Li, Chen Niu, Shuhao Fan, Huanhuan Yu, Wenjuan Wu, Xiangfei Feng, Cuixia Dai
{"title":"Correction of Non-Uniform Rotational Distortion in the Proximally Controlled Endoscopic OCTA","authors":"Zehua Guan,&nbsp;Qiang Li,&nbsp;Chen Niu,&nbsp;Shuhao Fan,&nbsp;Huanhuan Yu,&nbsp;Wenjuan Wu,&nbsp;Xiangfei Feng,&nbsp;Cuixia Dai","doi":"10.1002/jbio.202400467","DOIUrl":"10.1002/jbio.202400467","url":null,"abstract":"<div>\u0000 \u0000 <p>Endoscopic Optical Coherence Tomography (OCT) can provide high-resolution cross-sectional images for internal organ tissues. Combining the endoscopic imaging with Optical Coherence Tomography Angiography (OCTA), information of blood vessels in superficial lumen tissues is expected to be acquired. However, in endoscopic OCT systems using proximal scanning probes, performance of OCTA encounters significant challenges due to non-uniform rotational distortion (NURD) caused by the non-constant rotation of the distal imaging unit. In this study, we proposed a registration method for endoscopic OCTA imaging in a proximally controlled OCT System. Global registration and A-line registration were employed to correct the distortion caused by mechanical friction between the catheter sheath and torque coil. Experimental performances in both microfluidic channel and rat rectum show significant correction of NURD. Our study achieved the first implementation of endoscopic OCTA under a spiral B-scan rotation scheme in a proximally controlled OCT system, facilitating clear visualization of blood flow.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental Research on the Process and Performance of Composite Dressing-Assisted Laser Joining of Ruptured Tendons 复合敷料辅助激光连接断裂肌腱的工艺与性能试验研究。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-02-03 DOI: 10.1002/jbio.202400528
Jun Huang, Yanyu Li, Mintao Yan, Jinjin Wu, Kehong Wang
{"title":"Experimental Research on the Process and Performance of Composite Dressing-Assisted Laser Joining of Ruptured Tendons","authors":"Jun Huang,&nbsp;Yanyu Li,&nbsp;Mintao Yan,&nbsp;Jinjin Wu,&nbsp;Kehong Wang","doi":"10.1002/jbio.202400528","DOIUrl":"10.1002/jbio.202400528","url":null,"abstract":"<div>\u0000 \u0000 <p>Tendon tissue plays an important role in transmitting the force, increasing the incidence of serious tendon injuries. The clinical method of tendon tissue repair is contact surgical suture, which has the problem of high requirements for surgery. Laser has a noncontact feature that can reduce postoperative complications. However, the tissue has low tensile strength due to the weak ability to absorb the energy. Dressing-assisted laser joining of ruptured tendons can improve the tensile strength of ruptured tendon tissue. The enhancement effect of the dressing was tested, and the mechanical properties and thermal damage of the tendon tissue were analyzed. The results show that with 0.005% SWCNTS +0.3% ICG, the tensile strength can be achieved at 1.30 MPa, the collagen content can be achieved at 27.68% and the degree of thermal denaturation is only 0.31. The results have important value for further research on tendon tissue repair techniques.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Portable Nd:YAG Laser-Enhanced Photoacoustic Spectral Sensing for Breast Tissues: Toward Oncological Theranostics 便携式Nd:YAG激光增强光声光谱传感乳腺组织:肿瘤治疗。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-02-01 DOI: 10.1002/jbio.202400430
Suhel Khan, Sramana Mukhopadhyay, M. S. Ansari, R. K. Patidar, Saikat Das, Srivathsan Vasudevan
{"title":"Portable Nd:YAG Laser-Enhanced Photoacoustic Spectral Sensing for Breast Tissues: Toward Oncological Theranostics","authors":"Suhel Khan,&nbsp;Sramana Mukhopadhyay,&nbsp;M. S. Ansari,&nbsp;R. K. Patidar,&nbsp;Saikat Das,&nbsp;Srivathsan Vasudevan","doi":"10.1002/jbio.202400430","DOIUrl":"10.1002/jbio.202400430","url":null,"abstract":"<div>\u0000 \u0000 <p>A solid-state laser is preferred for generating light in a photoacoustic (PA) system because of its high energy and coherence. However, conventional Nd:YAG lasers are bulky, complex, and expensive. This article introduces a portable alternative: a custom-built Nd:YAG laser with an in-house power supply that delivers 0–30 A current pulses with a 1500 μs pulse width, providing efficient thermal management. A pockels cell driver generates 10 ns pulses with 3.84 mJ/c<i>m</i>\u0000 <sup>2</sup> laser energy density. Implemented for noninvasive breast cancer diagnosis, The peak frequency obtained from three different samples was 0.23 ± 0.1, 0.26 ± 0.13, and 1.80 ± 0.14 MHz, respectively, for Normal, Fibrotic, and Tumor tissues. In addition to the dominant frequency peaks the spectral energy of the PASR spectra has also been investigated to characterize the breast tissue samples. The developed laser successfully differentiates between carcinoma, fibrocystic disease, and normal breast tissue based on quantitative PA spectral parameters.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between the Optical Properties of Articular Cartilage and the Biomechanical Parameters of the Tissue 关节软骨光学特性与组织生物力学参数的关系。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-01-31 DOI: 10.1002/jbio.202400460
Iman Kafian-Attari, Mohammad Ebrahimi, Ervin Nippolainen, Arash Mirhashemi, Petri Paakkari, Florian Bergmann, Florian Foschum, Alwin Kienle, Juha Töyräs, Isaac Afara
{"title":"The Relationship Between the Optical Properties of Articular Cartilage and the Biomechanical Parameters of the Tissue","authors":"Iman Kafian-Attari,&nbsp;Mohammad Ebrahimi,&nbsp;Ervin Nippolainen,&nbsp;Arash Mirhashemi,&nbsp;Petri Paakkari,&nbsp;Florian Bergmann,&nbsp;Florian Foschum,&nbsp;Alwin Kienle,&nbsp;Juha Töyräs,&nbsp;Isaac Afara","doi":"10.1002/jbio.202400460","DOIUrl":"10.1002/jbio.202400460","url":null,"abstract":"<p>This study investigates the relationship between the optical properties of articular cartilage with its biomechanical parameters. The absorption and reduced scattering coefficients of articular cartilage, and average maximum penetration depth, average maximum lateral spread, and average path length of photons were estimated by optical measurements and Monte Carlo simulation. The equilibrium and instantaneous moduli, and initial fibrillar network, strain-dependent fibrillar network, and nonfibrillar network moduli, and initial and deformation-dependent permeability of the tissue were estimated by multistep stress-relaxation measurement and fibril-reinforced poroelastic modeling. The relationship between the optical properties and biomechanical parameters was assessed using predictive regression modeling. A strong relationship was found between reduced scattering coefficients, averaged maximum penetration depth, averaged maximum lateral spread, and average path length of photons with equilibrium, instantaneous, and initial fibrillar network moduli. We attribute this relationship to the collagen fibers as the main contributor to the scattering and biomechanical properties of the tissue.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400460","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Non-invasive Lung Disease Study of Exhaled Breath Nitric Oxide Based on Ultraviolet Differential Absorption Spectroscopy Techniques 基于紫外差分吸收光谱技术的呼气一氧化氮无创肺部疾病研究。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-01-28 DOI: 10.1002/jbio.202400481
Chaoyang Li, Xiaoning Chen, Wei Li, Xuan Zhou, Huiyuan Gong
{"title":"A Non-invasive Lung Disease Study of Exhaled Breath Nitric Oxide Based on Ultraviolet Differential Absorption Spectroscopy Techniques","authors":"Chaoyang Li,&nbsp;Xiaoning Chen,&nbsp;Wei Li,&nbsp;Xuan Zhou,&nbsp;Huiyuan Gong","doi":"10.1002/jbio.202400481","DOIUrl":"10.1002/jbio.202400481","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, a non-invasive device based on ultraviolet differential absorption spectroscopy (UV-DOAS) technology for detecting fractional exhaled nitric oxide (FeNO)was developed and clinically validated in patients with various lung diseases. The diagnostic potential of FeNO was explored by analysing subgroups of patients with lung cancer, nodules, and other disease. The results showed that FeNO concentrations were significantly higher in patients with malignant tumours than in healthy controls (<i>p</i> &lt; 0.01). The diagnostic efficacy of FeNO in different lung diseases was confirmed by ROC analysis: the AUC values were 0.925 for malignant tumours, 0.925 for suspected malignant/benign tumours, 0.792 for benign lesions, and 0.938 for infectious/inflammatory diseases. The significant postoperative FeNO level decrease supports the diagnostic use of FeNO in different stages of the disease. Compared with conventional electrochemical, chemiluminescent and fluorescent probe methods, the UV-DOAS technique has significant advantages regarding sensitivity and portability, suggesting its potential for clinical application.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep Learning and Hyperspectral Imaging for Liver Cancer Staging and Cirrhosis Differentiation 深度学习和高光谱成像在肝癌分期和肝硬化鉴别中的应用。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-01-28 DOI: 10.1002/jbio.202400557
Tianyi Hang, Danfeng Fan, Tiefeng Sun, Zhengyuan Chen, Xiaoqing Yang, Xiaoqing Yue
{"title":"Deep Learning and Hyperspectral Imaging for Liver Cancer Staging and Cirrhosis Differentiation","authors":"Tianyi Hang,&nbsp;Danfeng Fan,&nbsp;Tiefeng Sun,&nbsp;Zhengyuan Chen,&nbsp;Xiaoqing Yang,&nbsp;Xiaoqing Yue","doi":"10.1002/jbio.202400557","DOIUrl":"10.1002/jbio.202400557","url":null,"abstract":"<div>\u0000 \u0000 <p>Liver malignancies, particularly hepatocellular carcinoma (HCC), pose a formidable global health challenge. Conventional diagnostic techniques frequently fall short in precision, especially at advanced HCC stages. In response, we have developed a novel diagnostic strategy that integrates hyperspectral imaging with deep learning. This innovative approach captures detailed spectral data from tissue samples, pinpointing subtle cellular differences that elude traditional methods. A sophisticated deep convolutional neural network processes this data, effectively distinguishing high-grade liver cancer from cirrhosis with an accuracy of 89.45%, a sensitivity of 90.29%, and a specificity of 88.64%. For HCC differentiation specifically, it achieves an impressive accuracy of 93.73%, sensitivity of 92.53%, and specificity of 90.07%. Our results underscore the potential of this technique as a precise, rapid, and non-invasive diagnostic tool that surpasses existing clinical methods in staging liver cancer and differentiating cirrhosis.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wearable Multimodal Optical Analyzers: Physiological Variability and Reproducibility of Measurements 可穿戴式多模态光学分析仪:测量的生理变异性和可重复性。
IF 2 3区 物理与天体物理
Journal of Biophotonics Pub Date : 2025-01-28 DOI: 10.1002/jbio.202400527
Yu. I. Loktionova, E. V. Zharkikh, V. E. Parshakova, V. V. Sidorov, A. V. Dunaev
{"title":"Wearable Multimodal Optical Analyzers: Physiological Variability and Reproducibility of Measurements","authors":"Yu. I. Loktionova,&nbsp;E. V. Zharkikh,&nbsp;V. E. Parshakova,&nbsp;V. V. Sidorov,&nbsp;A. V. Dunaev","doi":"10.1002/jbio.202400527","DOIUrl":"10.1002/jbio.202400527","url":null,"abstract":"<div>\u0000 \u0000 <p>The work is devoted to the study of the physiological variability of the microcirculatory-tissue system (MTS) parameters under normal conditions and during functional tests. The results were obtained in vivo using multimodal wearable analyzers implementing methods of laser Doppler flowmetry and fluorescence spectroscopy. Comprehensive data analysis and calculation of the coefficients of variation of the MTS parameters of the human body for various topographic and anatomical areas of the skin were carried out. The obtained results showed higher values of the coefficient of variation of MTS parameters in the area of the toes and wrists, while the fingers and forehead skin showed lower levers of variation. In all areas of the study, reproducibility of the parameters obtained for the right and left areas of the study is observed.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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