Case Reports in Dermatology最新文献_第6页

Oral Mycosis Fungoides: Report of 2 Cases and Review of the Literature. 口腔蕈样真菌病2例报告并文献复习。

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Case Reports in Dermatology Pub Date : 2023-07-12 eCollection Date: 2023-01-01 DOI: 10.1159/000530935

Carolina Alexander-Savino, Alexandra Boye-Doe, Edith Bowers, Anne Beaven

{"title":"Oral Mycosis Fungoides: Report of 2 Cases and Review of the Literature.","authors":"Carolina Alexander-Savino, Alexandra Boye-Doe, Edith Bowers, Anne Beaven","doi":"10.1159/000530935","DOIUrl":"10.1159/000530935","url":null,"abstract":"Oral and laryngeal cutaneous T-cell lymphoma (CTCL) is rare and usually associated with poor prognosis. Here, we discuss 2 cases of oral CTCL that developed in heavily pretreated patients and provide a review of the literature. The first case is of a 46-year-old African American male with rapidly progressive disease, presenting with a lesion on his hard palate 6 months after being diagnosed with a CD4+CD8+ CTCL. His cutaneous disease was widespread with tumors on >80% of his body surface area. Unfortunately, the patient died 2 ½ years after his CTCL diagnosis and 7 months after developing the oral CTCL lesion. The second case is of a 38-year-old African American male with stage IIb CD3+CD4+CD30+ mycosis fungoides (MF), who developed a tumor on the hard palate 6 months after diagnosis. He received palliative radiation to the oral lesion and multiple lines of systemic therapy for pulmonary, laryngeal, esophageal, and gastric involvement. Biopsy of the gastric lesions showed a CD30+ T-cell lymphoma with the same clonal peak as in his skin but with large cell transformation. Brentuximab vendoin was started, and the patient is now in complete remission, 30 months later. From the 76 cases of oral CTCL that have been reported in the English language, six were of transformed MF. The most common sites affected were the tongue and palate, and the most common presentation were erythematous or ulcerated tumors, plaques, or nodules associated with dysphagia and pain. Oral CTCL typically occurs years after the initial diagnosis of CTCL and portend a poor prognosis with an average survival of just over 1 year after development of oral lesions.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/2c/cde-2023-0015-0001-530935.PMC10368101.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9880219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Uncommon Presentation of Neonatal Lupus Erythematosus: A Case Report. 新生儿红斑狼疮的罕见表现：病例报告。

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Case Reports in Dermatology Pub Date : 2023-06-06 eCollection Date: 2023-01-01 DOI: 10.1159/000530465

Sara Al Janahi, Raghda Al Maashari

引用次数: 0

Granulomatous Pigmented Purpuric Dermatosis in a Patient with (Inactive) Myasthenia Gravis: A Case Report and Review of the Literature. 肉芽肿性色素紫癜性皮肤病合并(非活动性)重症肌无力1例报告及文献复习。

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Case Reports in Dermatology Pub Date : 2023-05-25 eCollection Date: 2023-01-01 DOI: 10.1159/000530034

Apirada Dhekariyapak, Penpun Wattanakrai

{"title":"Granulomatous Pigmented Purpuric Dermatosis in a Patient with (Inactive) Myasthenia Gravis: A Case Report and Review of the Literature.","authors":"Apirada Dhekariyapak, Penpun Wattanakrai","doi":"10.1159/000530034","DOIUrl":"10.1159/000530034","url":null,"abstract":"Granulomatous pigmented purpuric dermatosis (GPPD) is a rare histologic variant of pigmented purpuric dermatosis (PPD) characterized by dermal histiocyte-rich interstitial infiltration with or without granuloma formation in addition to the other typical features of PPD. GPPD was previously observed more frequently to affect Asians and was reported to be associated with dyslipidemia. However, our literature search of 45 documented GPPD cases revealed an increasing prevalence in Caucasians in addition to dyslipidemia and associated autoimmune diseases. To date, etiopathogenesis of GPPD is unknown but may involve dyslipidemia, genetic and immunological factors such as autoimmune dysregulation or a sarcoidal reaction associated with C. acnes. GPPD is usually persistent and recalcitrant to treatments. We report a case of GPPD in a 57-year-old Thai woman with underlying myasthenia gravis who presented with a pruritic eruption on both lower legs. After treatment with 0.05% clobetasol propionate cream and oral colchicine, the lesion improved with marked flattening and disappeared with residual postinflammatory hyperpigmentation. We provide a literature review of the epidemiology, etiopathogenesis, concomitant comorbidities, clinical symptoms, dermatoscopic features, and treatments of GPPD.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9719351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MRI-Induced Neurosensory Events in Decorative Black Tattoos: Study by Advanced Experimental Methods. MRI诱发黑纹身神经感觉事件的实验研究

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Case Reports in Dermatology Pub Date : 2023-05-25 eCollection Date: 2023-01-01 DOI: 10.1159/000530220

Kasper Køhler Alsing, Ole Olsen, Christian Bender Koch, Rasmus Hvass Hansen, Daniel Pergament Persson, Klaus Qvortrup, Jørgen Serup

{"title":"MRI-Induced Neurosensory Events in Decorative Black Tattoos: Study by Advanced Experimental Methods.","authors":"Kasper Køhler Alsing, Ole Olsen, Christian Bender Koch, Rasmus Hvass Hansen, Daniel Pergament Persson, Klaus Qvortrup, Jørgen Serup","doi":"10.1159/000530220","DOIUrl":"10.1159/000530220","url":null,"abstract":"Adverse reactions in tattooed skin during magnetic resonance imaging (MRI) are rare but well known. Previous reports describe sudden burning pain in tattooed skin, sometimes accompanied by mild erythema and oedema when entering MRI scanners. The pathophysiology remains unclear, but simple direct thermal heating can be excluded. It has been hypothesized that MRI-triggered torque and traction create neural sensations from magnetic pigment particles. However, this case enlightens yet another possible mechanism. We present a 35-year-old woman experiencing reoccurring stinging sensations in three decorative black tattoos just seconds after the initiation of the MRI. Single-blind tests with handheld power magnets or a dummy could reproduce painful subjective feelings in her tattooed skin. Similar events were provoked during re-evaluation with MRI. Surprisingly, chemical analyses and electron microscopy of skin samples revealed carbon black as the colouring agent - no iron-based solids were detected. Our case demonstrates that MRI tattoo reactions are not limited to magnetic contaminants alone. More distinct subgroups of MRI-induced reactions may occur. We hypothesize that radiofrequency induction of surface currents in black carbon particles adjacent to sensory axons in the dermis may lead to neurosensations.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48126684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Unilateral Lichen Planus Pigmentosus with Blaschko's Line Distribution: A Case Report. 伴有布拉氏线分布的单侧扁平苔藓色素沉着症：病例报告

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Case Reports in Dermatology Pub Date : 2023-04-27 eCollection Date: 2023-01-01 DOI: 10.1159/000529632

Almuntsrbellah Almudimeegh, Mohammed Habib, Omar Alsuhaibani, Nawaf Alkhudhayri

引用次数: 1

Acral Fibrochondromyxoid Tumor Presenting as Enlarging Nodule Involving the Distal Fingertip and Hyponychium: A Case Report. 肢端纤维软骨粘液样瘤表现为扩大结节累及远端指尖及颏下:1例报告。

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Case Reports in Dermatology Pub Date : 2023-03-16 eCollection Date: 2023-01-01 DOI: 10.1159/000529568

Rhiannon C Miller, Cynthia M Magro, Laura E Melnick, Shari R Lipner

引用次数: 0

Diagnostic Utility of TUNEL Staining for Degenerative Keratoacanthoma Requiring Pathologic Differentiation from Seborrheic Keratosis. TUNEL染色对需要与脂溢性角化病病理鉴别的退行性角棘瘤的诊断价值。

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Case Reports in Dermatology Pub Date : 2023-03-16 eCollection Date: 2023-01-01 DOI: 10.1159/000529728

Mari Nakanishi, Makoto Kondo, Koji Habe, Akinobu Hayashi, Keiichi Yamanaka

引用次数: 0

Idiopathic Acroosteolysis: A Novel Cutaneous Sign Can Help Identify the Condition Early. 特发性骨溶解症：一种新的皮肤体征有助于早期识别这种疾病。

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Case Reports in Dermatology Pub Date : 2023-03-15 eCollection Date: 2023-01-01 DOI: 10.1159/000529727

Samir Shrestha, Bashant Regmi, Raksha Pathak, George Kroumpouzos

{"title":"Idiopathic Acroosteolysis: A Novel Cutaneous Sign Can Help Identify the Condition Early.","authors":"Samir Shrestha, Bashant Regmi, Raksha Pathak, George Kroumpouzos","doi":"10.1159/000529727","DOIUrl":"10.1159/000529727","url":null,"abstract":"Acroosteolysis (AO) is a rare condition characterized by resorption of the distal phalanges of the fingers and/or toes. It can be familial, idiopathic (IAO), occupational, or secondary. Other authors suggest a classification into primary (genetic disorders, lysosomal storage disorders) or secondary AO. Various skin and nail changes have been reported in this condition. However, the cutaneous change on the affected digit(s)/toe(s) during the natural course of AO has been poorly documented. A 5-year-old girl presented with a 3-month history of a distinct transverse boundary between normal skin proximally and affected crusted skin overlying osteolysis distally (\"split\" sign) on the plantar surface of the third toe. This boundary gradually elongated circumferentially to involve the dorsal surface. The mother gave a similar history of a delimitation line on the 2nd, 4th, and 5th toes of the right foot with durations of 3 months, 1 year, and 2 years, respectively, that disappeared before she noticed a shortening of those toes. X-rays revealed partial resorption of the terminal phalanx of the third toe and several lytic changes in the middle and terminal phalanx of the second, fourth, and fifth toes. The clinical features, radiology findings, and a workup that helped rule out conditions associated with AO (secondary AO) helped establish the diagnosis of IAO in our patient. This case study highlights that the natural course of IAO includes distinct skin findings, such as the \"split\" sign that we describe. This sign can help identify the condition early.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/48/cde-2023-0015-0001-529727.PMC10018418.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9145207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous Manifestations of Sarcoidosis Seen in a Patient with a History of Tuberous Sclerosis. 一名有结节性硬化症病史的患者身上出现的肉样瘤病皮肤表现。

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Case Reports in Dermatology Pub Date : 2023-02-15 eCollection Date: 2023-01-01 DOI: 10.1159/000529159

Seth Bernacki, Paarth Dodia, Mikél Elizabeth Muse, Luke Maxfield

引用次数: 0

A Diagnostically Challenging Case of De Novo Febrile Ulceronecrotic Mucha-Habermann Disease with Fatal Pulmonary Involvement: A Case Report. 一例诊断困难的新发热性溃疡性穆查-哈伯曼病伴致命肺部受累病例：病例报告。

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Case Reports in Dermatology Pub Date : 2023-01-18 eCollection Date: 2023-01-01 DOI: 10.1159/000528500

Waseem Alhawsawi, Khalid Al Hawsawi, Bashaer Almahdi, Shahad Alkidaiwi, Khlood Alzubaidy, Reema Alhuthayli, Abdulmohsin Algethami, Alhusain Alshareef

{"title":"A Diagnostically Challenging Case of De Novo Febrile Ulceronecrotic Mucha-Habermann Disease with Fatal Pulmonary Involvement: A Case Report.","authors":"Waseem Alhawsawi, Khalid Al Hawsawi, Bashaer Almahdi, Shahad Alkidaiwi, Khlood Alzubaidy, Reema Alhuthayli, Abdulmohsin Algethami, Alhusain Alshareef","doi":"10.1159/000528500","DOIUrl":"10.1159/000528500","url":null,"abstract":"The febrile ulceronecrotic Mucha-Habermann disease is a rare and potentially lethal variant of pityriasis lichenoides et varioliformis acuta (PLEVA). It is characterized by a sudden onset of ulceronecrotic skin lesions associated with high fever and systemic symptoms. Herein, we report a 23-year-old male, not known to have any medical illnesses, presented with a month-long history of persistent fever of unknown origin associated with a sudden onset of progressive diffuse necrotic ulcers and widespread papulosquamous lesions. Pan CT showed enlarged lymph nodes in the cervix, chest, and abdomen. Unfortunately, a skin biopsy was done late, showing features consistent with PLEVA. Few days after admission, despite being on intravenous methylprednisolone, our patient rapidly deteriorated by showing severe acute respiratory symptoms and consequently died. In spite of the continuous addition of new case reports to the literature, no definite diagnostic criteria have been established, leading to late or missed cases, and an optimum treatment is still waiting.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/9e/cde-2023-0015-0001-528500.PMC9850257.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9228132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0