Case Reports in Dermatology最新文献

{"title":"Kerion Celsi in Elderly Female, Caused by <i>Trichophyton rubrum</i>: Case Report.","authors":"Andraž Jahič, Jan Stanič, Rok Tomazin, Mateja Dolenc Voljč","doi":"10.1159/000547156","DOIUrl":"10.1159/000547156","url":null,"abstract":"<p><strong>Introduction: </strong>Kerion celsi is a form of deep inflammatory tinea capitis, presenting with suppurative, tender plaque, often with pustules and purulent drainage. Tinea capitis is believed to be increasing in incidence worldwide. It mostly affects children and is most commonly caused by zoophilic dermatophytes. Globally, the most common transmission route is anthropophilic.</p><p><strong>Case presentation: </strong>Here, we present a case of a 92-year-old female without associated chronic diseases, who lived alone in urban apartment and developed kerion in addition to having chronic untreated toenail onychomycosis and tinea pedis. Using PCR, we confirmed <i>Trichophyton rubrum</i> as the causative pathogen of toenail onychomycosis and kerion, suspecting autoinoculation pattern of transmission of dermatophytes from feet to the scalp. With the literature review, we discovered sporadic case reports, linking toenail onychomycosis caused by <i>T. rubrum</i> to development of kerion and kerion-like lesions in adult patients.</p><p><strong>Conclusion: </strong>Our case report: (1) adds another interesting case to series of rare cases of <i>T. rubrum</i> causing kerion in elderly, suspecting it is in fact more common than thought, (2) highlights PCR as a useful diagnostic tool for fast diagnosis and implementation of appropriate antifungal therapy, (3) recognizes a pattern of autoinoculation transmission of <i>T. rubrum</i> from toenail onychomycosis to the scalp, causing kerion celsi in elderly.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"304-310"},"PeriodicalIF":0.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Importance of Histopathology in the Diagnosis of Annular Lichenoid Dermatitis of Youth: A Case Report.","authors":"Leart Bërdica, Teona Bushati, Sindi Shandro, Entela Shkodrani, Sabina Dedej, Ermira Vasili","doi":"10.1159/000546701","DOIUrl":"10.1159/000546701","url":null,"abstract":"<p><strong>Introduction: </strong>Annular lichenoid dermatitis of youth (ALDY) is a rare and underreported dermatologic condition. It primarily affects children and adolescents. Clinically, ALDY presents as erythematous annular macules or plaques with raised borders and hypopigmented centers, predominantly affecting the trunk and flexural areas. The etiology remains unknown, and the condition poses a diagnostic challenge due to its resemblance to other annular dermatoses.</p><p><strong>Case presentation: </strong>A 5-year-old female presented with asymptomatic annular erythematous lesions on the trunk, abdomen, lumbar region, and flanks. Initial differential diagnoses included annular erythema, tinea corporis, morphea, and mycosis fungoides. A mycological examination was negative, and symptomatic treatment with hydrocortisone and pimecrolimus led to temporary lesion resolution, but recurrence followed treatment cessation. A skin biopsy revealed histopathological features characteristic of ALDY, including basal layer vacuolization and a prominent lichenoid lymphocytic infiltrate. Immunohistochemical analysis supported the diagnosis.</p><p><strong>Conclusion: </strong>ALDY remains a diagnostic challenge due to its clinical overlap with other annular dermatoses. Histopathological examination is essential for definitive diagnosis. The chronic and recurrent nature of ALDY underscores the importance of long-term management strategies, including topical corticosteroids and immunomodulators. Awareness of ALDY among dermatologists can aid in early recognition and appropriate management, ultimately improving patient outcomes.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"311-317"},"PeriodicalIF":0.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous Rosai-Dorfman Disease: A Report of 2 Cases and a Review of Recent Literature (2018-2023).","authors":"Fatemeh Mohaghegh, Mina Saber, Parvin Rajabi, Haniyeh Sohrabi","doi":"10.1159/000546382","DOIUrl":"10.1159/000546382","url":null,"abstract":"<p><strong>Introduction: </strong>Rosai-Dorfman disease (RDD) is a rare, benign histiocytic disorder that can present as isolated cutaneous RDD (CRDD), often mimicking other dermatologic conditions and complicating diagnosis.</p><p><strong>Case presentation: </strong>We report two cases of CRDD: one with palms and soles involvement, and another as an exophytic facial mass, initially misdiagnosed and unsuccessfully treated. Dermoscopy revealed distinctive features, including yellow ovoid structures, linear vessels, and cotton-like white globules. Histopathological and immunohistochemical analyses confirmed CRDD with histiocytic infiltration and emperipolesis, key histological markers of CRDD.</p><p><strong>Conclusion: </strong>A review of 53 cases (2018-2023) highlights CRDD's clinical variability, common anatomical sites, and diverse treatment responses, emphasizing the need for individualized management and early recognition for optimal treatment. These findings contribute to a broader understanding of CRDD and support a multidisciplinary approach to optimizing patient care.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"204-223"},"PeriodicalIF":0.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12185066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photo-Induced Sarcoidosis in a Diabetic Patient Receiving Metformin Hydrochloride.","authors":"Hanae Fujita, Yuki Mizutani, Akinobu Hayashi, Keiichi Yamanaka","doi":"10.1159/000546617","DOIUrl":"10.1159/000546617","url":null,"abstract":"<p><strong>Introduction: </strong>Sarcoidosis can present with a wide range of skin manifestations, occurring in approximately 30% of sarcoidosis patients. However, photosensitivity in cutaneous sarcoidosis is exceedingly rare. This case report details a unique presentation of photosensitive cutaneous sarcoidosis, its diagnosis, and treatment.</p><p><strong>Case presentation: </strong>A 65-year-old woman presented with numerous erythematous lesions on her eyelids, persisting for 5 months despite treatments with fexofenadine hydrochloride and topical steroids. Her medical history included diabetes mellitus and dyslipidemia, managed with rosuvastatin, metformin, and a combination of teneligliptin and canagliflozin. After discontinuation of rosuvastatin due to suspected interstitial granulomatous dermatitis, her lesions remained unchanged. Clinical examination revealed annular plaques on sun-exposed areas, and skin biopsy showed noncaseating granulomas with eosinophilic infiltration. Elevated serum ACE, calcium, and soluble interleukin-2 receptor levels supported a diagnosis of cutaneous sarcoidosis. Lesions were resistant to systemic and topical steroid treatments, prompting suspicion of photosensitivity. Photo testing identified UVB sensitivity during metformin use, which resolved after discontinuation of the drug. The patient's lesions improved 1 week after stopping metformin, enabling prednisone tapering without recurrence.</p><p><strong>Conclusion: </strong>This case highlights metformin as a potential photosensitizing agent in cutaneous sarcoidosis. While the relationship between diabetes mellitus and sarcoidosis remains unclear, chronic inflammation in diabetes may influence sarcoidosis progression. In cases of refractory cutaneous sarcoidosis despite systemic steroid treatment, it is crucial to consider the coexistence of photosensitivity, particularly drug-induced photosensitivity. Therefore, carefully reviewing the patient's medication history is essential for accurate diagnosis and management.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"284-290"},"PeriodicalIF":0.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erosive Pustular Dermatosis and Amivantamab for Lung Cancer: A Case Report.","authors":"Yseult Senterre, Amandine Bouillenne, Murielle Sabatiello, Anne-Sophie Demoulin, Arjen F Nikkels","doi":"10.1159/000546616","DOIUrl":"10.1159/000546616","url":null,"abstract":"<p><strong>Introduction: </strong>Amivantamab is a monoclonal antibody against EGFR and MET receptors, indications for certain types of non-small cell lung cancer. Due to its mechanisms, cutaneous adverse effects are frequent and numerous.</p><p><strong>Case presentation: </strong>A 67-year-old woman with metastatic adenosquamous carcinoma, stage T3N2M1c, was treated with amivantamab after the first-line chemotherapy failed. Despite prophylactic oral tetracyclines, she developed severe erosive pustular dermatosis (EPD) affecting more than 50% of her scalp, forcing to cut short her hair to provide adequate local care.</p><p><strong>Conclusion: </strong>EPD is an exceptional and severe adverse event of amivantamab, requiring oral steroids, tetracyclines and appropriate local care with antibiotic creams. Clinicians should be aware of this complication as early therapeutic intervention is mandatory to avoid deleterious consequences and spontaneous recurrences.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"263-267"},"PeriodicalIF":0.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Aquagenic Pruritus Successfully Treated by β-Alanine: A Case Report.","authors":"Farzad Alinaghi, Jesper Elberling","doi":"10.1159/000545842","DOIUrl":"10.1159/000545842","url":null,"abstract":"<p><strong>Introduction: </strong>Aquagenic pruritus is a chronic debilitating itchy skin condition triggered by water exposure with limited treatment options.</p><p><strong>Case presentation: </strong>Here, we present a case of primary aquagenic pruritus in an adult male who was successfully treated with β-alanine. Treatment efficacy was maintained at 20-week follow-up.</p><p><strong>Conclusion: </strong>This study adds to the body of evidence supporting a role for β-alanine as an efficient and safe treatment option in patients with aquagenic pruritus. Furthermore, it includes a discussion of the pharmacodynamics of β-alanine and provides an insight into the pathophysiology of aquagenic pruritus.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"252-254"},"PeriodicalIF":0.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Recalcitrant Case of Hidradenitis Suppurativa: Successful Combination of Biologic, Antibiotic, and Surgical Therapy.","authors":"Nawa Arif, Sylke Schneider-Burrus","doi":"10.1159/000546384","DOIUrl":"10.1159/000546384","url":null,"abstract":"<p><strong>Introduction: </strong>Hidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory skin disease that leads to painful nodules, abscesses, and fistulas.</p><p><strong>Case presentation: </strong>This case describes the treatment of a 49-year-old male patient with progressive and massively inflamed HS for 20 years who also suffered from heart failure (NYHA II-III, EF 35-40%) and hypochromic microcytic anaemia (Hb 7.8 g/dL). Upon presentation, he was suffering from fatigue and severe pain (8-9/10, NRS). Due to prolonged immobility, knee and hip joint contractures with extension deficits were present. At the initial presentation, communicating, and purulent sinus tracts were observed bilaterally from the gluteal to femoral region and perianal area. Hurley score III, HS-PGA score: very severe, Dermatology Life Quality Index (DLQI) score: 19, ISH4 score: severe (16). Under adalimumab s.c. 40 mg/week combined with clindamycin (300 mg bd), the condition had worsened. The patient was admitted to the hospital for i.v. administration of ertapenem 1 g/day for 14 days in preparation for sinus tract resection. With an Hb level of 7.8 g/dL, the patient received iron carboxymaltose and erythropoietin. After a significant reduction in inflammatory markers (leukocytes 17.11/nL to 7.42/nL), a large excision of the sinus tracts was performed bilaterally in the gluteal region and left femoral area. Following 4 weeks of wound granulation, split-thickness skin grafting was performed. The knee and hip joint contractures improved with intensive physiotherapy. After surgery, the patient received antibiotic therapy with clindamycin, rifampicin, and metronidazole (clindamycin 600 mg, rifampicin 300 mg, metronidazole 500 mg, each p.o. 2×/day). In parallel, anti-inflammatory therapy with secukinumab 300 mg s.c. twice a month was initiated. Over the following 3 months, no progression or recurrence occurred. Quality of life and pain levels improved significantly under the therapy (DLQI from 19 to 10, pain from 8 to 9 to 3/10 NRS).</p><p><strong>Conclusion: </strong>In extensive cases of HS, a combination of surgical and conservative therapy is necessary. We demonstrate that severe cases can be successfully treated with a combination of antibiotic, anti-inflammatory, and surgical therapy.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"268-273"},"PeriodicalIF":0.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Sequential Combination of Long-Pulsed Potassium Titanyl Phosphate 532-nm and Quasi Long-Pulsed 1,064-nm Nd:YAG Laser Therapy for Port-Wine Stain Treatment: A Case Report.","authors":"Laura Brufau, Pablo Russo, Alessandra Zevini, Daniela Martinelli, Riccardo Barini","doi":"10.1159/000546702","DOIUrl":"10.1159/000546702","url":null,"abstract":"<p><strong>Introduction: </strong>Port-wine stains (PWS), congenital vascular malformations affecting approximately 0.3-0.5% of live births, present as pink to red patches that darken and thicken over time, potentially leading to disfigurement, functional complications, and significant psychosocial distress. While pulsed dye lasers (PDLs) are considered the standard treatment, they often require multiple sessions and exhibit variable clearance rates. Alternative laser modalities, such as the 532-nm potassium titanyl phosphate (KTP) laser, have shown promising results, particularly in PDL-resistant cases. However, managing complex PWS with diverse vessel calibers, hypertrophy, and scarring remains a challenge, highlighting the need for tailored treatment strategies.</p><p><strong>Case presentation: </strong>A 22-year-old female presented with a complex PWS affecting the V2 dermatome of the left hemiface, including the lower eyelid, inner canthus, and associated lip/gingival hypertrophy and scarring from previous surgical intervention. She underwent five monthly sessions of a novel sequential laser protocol. This protocol combined long-pulsed KTP 532-nm laser treatment with quasi long-pulsed 1,064-nm Nd:YAG laser treatment to target both larger and smaller superficial vascular structures. In the final two sessions, ablative Er:YAG 2,940-nm laser treatment was added to address existing scars. Fluence and pulse duration were dynamically adjusted throughout the treatment course. Post-treatment care consisted of gentle skincare, emollients, and broad-spectrum sunscreen. The patient achieved significant lightening of the lesion, reduced vascular prominence and hypertrophy, improved facial symmetry, and softening of scars, with minimal and transient side effects.</p><p><strong>Conclusion: </strong>This case demonstrates the potential of a tailored, sequential combination of long-pulsed KTP 532-nm, quasi long-pulsed 1,064-nm Nd:YAG, and ablative Er:YAG 2,940-nm lasers for effectively managing complex PWS with associated hypertrophy and scarring. This multimodal approach, adjusting parameters to target specific lesion characteristics, suggests a promising strategy for achieving superior esthetic and functional outcomes in challenging PWS cases and improving patient quality of life.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"274-283"},"PeriodicalIF":0.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malignant Hidroacanthoma Simplex: A Case Report.","authors":"Xiangxiang Ren, Tianhao Xie, Lingyun Liu, Fan Yang, Meng Zhang","doi":"10.1159/000546700","DOIUrl":"10.1159/000546700","url":null,"abstract":"<p><strong>Introduction: </strong>Malignant hidroacanthoma simplex (MHS) is an exceedingly rare cutaneous neoplasm with limited documented cases. This report highlights a distinctive case of MHS with prolonged clinical evolution, emphasizing its diagnostic challenges and management outcomes.</p><p><strong>Case presentation: </strong>A 64-year-old female presented with a right lumbar mass persisting for over 2 decades, exhibiting progressive enlargement in the past 5 years. Clinical examination revealed a solitary reddish-brown proliferative plaque (3.5 cm × 4.0 cm) on the right waist, characterized by irregular borders, a rough surface, and reddish-brown crusts. Histopathological findings included hyperkeratosis, irregular epidermal hyperplasia, hypertrophic stratum spinosum, and tumor cells displaying pale eosinophilic cytoplasm, vacuolated nuclei, small nucleoli, and atypical mitotic figures. Notably, tumor cells were confined to the epidermis without dermal invasion. The patient underwent local extended excision, and postoperative surveillance over 15 months demonstrated no evidence of recurrence or lymph node metastasis.</p><p><strong>Conclusion: </strong>This case underscores the indolent yet locally persistent nature of MHS. Complete surgical excision remains the cornerstone of management, with favorable outcomes achievable in the absence of dermal infiltration. Long-term follow-up is critical to monitor potential recurrence.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"246-251"},"PeriodicalIF":0.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different Course of Nonpigmented Skin Cancers in Patients Treated with Immunosuppression after Organ Transplantation: A Case Series.","authors":"Monika Łącka, Paulina Bernecka, Karolina Kondej, Jerzy Jankau","doi":"10.1159/000545836","DOIUrl":"10.1159/000545836","url":null,"abstract":"<p><strong>Introduction: </strong>In 2023, solid organs were transplanted in 1,400 patients in Poland. Nonmelanoma skin cancer such as squamous cell carcinoma (SCC) or basal cell carcinoma (BCC) is the most common malignancy in solid organ transplant recipients. Aims of the study were to present cases and discuss the possible course of skin cancer in patients after organ transplantation.</p><p><strong>Case presentation: </strong>The study involved 3 patients after organ transplantation treated for skin cancer in the Department of Plastic Surgery of the University of Gdańsk in the years 2020-2023. Each patient is an example of a different course of the disease. In the case of patients treated with immunosuppression, a more aggressive course of the cancer should be considered, which may take various forms. One of the variants that we are dealing with in the first patient is the occurrence of multiple lesions, the co-occurrence of SCC and BCC, and frequent local recurrences. In the case of the second patient, we are dealing with a very aggressive course despite the early initiation of appropriate treatment. Another example of a different course is an atypical clinical picture that makes it difficult to make the correct diagnosis, which we observe in the third patient.</p><p><strong>Conclusions: </strong>Our study demonstrates that due to the much higher morbidity, aggressive, rapid progression of the skin cancer disease, and unfavorable prognosis, population after transplantation requires a special oncological approach.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"196-203"},"PeriodicalIF":0.9,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}