{"title":"β-丙氨酸成功治疗原发性水源性瘙痒1例。","authors":"Farzad Alinaghi, Jesper Elberling","doi":"10.1159/000545842","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Aquagenic pruritus is a chronic debilitating itchy skin condition triggered by water exposure with limited treatment options.</p><p><strong>Case presentation: </strong>Here, we present a case of primary aquagenic pruritus in an adult male who was successfully treated with β-alanine. Treatment efficacy was maintained at 20-week follow-up.</p><p><strong>Conclusion: </strong>This study adds to the body of evidence supporting a role for β-alanine as an efficient and safe treatment option in patients with aquagenic pruritus. Furthermore, it includes a discussion of the pharmacodynamics of β-alanine and provides an insight into the pathophysiology of aquagenic pruritus.</p>","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":"17 1","pages":"252-254"},"PeriodicalIF":0.9000,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233996/pdf/","citationCount":"0","resultStr":"{\"title\":\"Primary Aquagenic Pruritus Successfully Treated by β-Alanine: A Case Report.\",\"authors\":\"Farzad Alinaghi, Jesper Elberling\",\"doi\":\"10.1159/000545842\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Aquagenic pruritus is a chronic debilitating itchy skin condition triggered by water exposure with limited treatment options.</p><p><strong>Case presentation: </strong>Here, we present a case of primary aquagenic pruritus in an adult male who was successfully treated with β-alanine. Treatment efficacy was maintained at 20-week follow-up.</p><p><strong>Conclusion: </strong>This study adds to the body of evidence supporting a role for β-alanine as an efficient and safe treatment option in patients with aquagenic pruritus. Furthermore, it includes a discussion of the pharmacodynamics of β-alanine and provides an insight into the pathophysiology of aquagenic pruritus.</p>\",\"PeriodicalId\":9619,\"journal\":{\"name\":\"Case Reports in Dermatology\",\"volume\":\"17 1\",\"pages\":\"252-254\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-06-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233996/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Dermatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000545842\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Dermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000545842","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Primary Aquagenic Pruritus Successfully Treated by β-Alanine: A Case Report.
Introduction: Aquagenic pruritus is a chronic debilitating itchy skin condition triggered by water exposure with limited treatment options.
Case presentation: Here, we present a case of primary aquagenic pruritus in an adult male who was successfully treated with β-alanine. Treatment efficacy was maintained at 20-week follow-up.
Conclusion: This study adds to the body of evidence supporting a role for β-alanine as an efficient and safe treatment option in patients with aquagenic pruritus. Furthermore, it includes a discussion of the pharmacodynamics of β-alanine and provides an insight into the pathophysiology of aquagenic pruritus.
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