Case Reports in Neurological Medicine最新文献

Posterior Reversible Encephalopathy Syndrome Induced by Mirtazapine Overdose: A Case Report. 米氮平过量致后部可逆性脑病综合征1例。

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Case Reports in Neurological Medicine Pub Date : 2025-06-06 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/4690032

Min-Chiao Tsai, Wei-Hao Lin

{"title":"Posterior Reversible Encephalopathy Syndrome Induced by Mirtazapine Overdose: A Case Report.","authors":"Min-Chiao Tsai, Wei-Hao Lin","doi":"10.1155/crnm/4690032","DOIUrl":"10.1155/crnm/4690032","url":null,"abstract":"Introduction: Posterior reversible encephalopathy syndrome (PRES) is a neurological emergency typically associated with hypertension or drug toxicity. Although mirtazapine is not a classical serotonergic agent, overdose may induce serotonin syndrome, which can contribute to PRES. Case Presentation: A 50-year-old woman presented with seizures, impaired consciousness, and autonomic instability following ingestion of > 300 mg mirtazapine. Magnetic resonance image (MRI) revealed vasogenic edema in the parieto-occipital and frontal lobes. Her clinical features fulfilled the Hunter criteria for serotonin syndrome. Treatment with cyproheptadine led to full clinical and radiological recovery. Discussion: Serotonin syndrome may disrupt cerebral autoregulation and impair endothelial integrity, contributing to PRES. Although rare, similar cases have been reported with other serotonergic agents. This is the first reported case of mirtazapine overdose resulting in serotonin syndrome-associated PRES. Conclusion: Clinicians should recognize that mirtazapine overdose can cause serotonin syndrome and secondary PRES. Early identification and serotonin antagonism are crucial for recovery and prevention of sequelae.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2025 ","pages":"4690032"},"PeriodicalIF":0.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pudendal Nerve Irritation as Unique Symptom of Pelvic Congestion Syndrome. 阴部神经刺激是盆腔充血综合征的独特症状。

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Case Reports in Neurological Medicine Pub Date : 2025-06-03 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/7952359

Christos Dimopoulos, Sotirios Bisdas, Theodosios Bisdas

{"title":"Pudendal Nerve Irritation as Unique Symptom of Pelvic Congestion Syndrome.","authors":"Christos Dimopoulos, Sotirios Bisdas, Theodosios Bisdas","doi":"10.1155/crnm/7952359","DOIUrl":"10.1155/crnm/7952359","url":null,"abstract":"Pelvic congestion syndrome (PCS) is an underdiagnosed but not rare cause of chronic pelvic pain, affecting approximately 10%-30% of women of reproductive age. It is characterized by venous insufficiency and dilation of the ovarian and pelvic veins, often presenting with symptoms that worsen during menstruation or prolonged standing, and improve in the supine position. Dyspareunia and a sensation of pelvic heaviness are also frequently reported. Neurological manifestations-such as pudendal or femoral nerve irritation-are rare but may offer key diagnostic clues. We present a case of a 30-year-old woman with right-sided pelvic pain radiating to the groin and proximal thigh, consistent with neural irritation. Magnetic neurography revealed dilated pelvic veins in close proximity to the right psoas muscle and the L5 nerve root, suggesting perineural venous engorgement. Selective venography confirmed bilateral ovarian vein insufficiency, and the patient underwent successful embolization with Ruby coils and adjunct sclerotherapy. Postoperative recovery was uneventful, with complete resolution of symptoms. Follow-up at 1 year showed no recurrence, and the patient later achieved a successful pregnancy. This case highlights the potential for pelvic venous congestion to mimic or cause neural symptoms and emphasizes the diagnostic value of magnetic neurography in complex pain presentations. Endovascular treatment proved safe and effective, even in cases with neurological involvement.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2025 ","pages":"7952359"},"PeriodicalIF":0.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-NMDAR Encephalitis With Serial Negative MRI Findings: An Evaluation Using Autoimmune Psychosis Criteria. 具有一系列MRI阴性表现的抗nmdar脑炎：使用自身免疫性精神病标准的评估

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Case Reports in Neurological Medicine Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/4561447

Satoshi Saito, Go Taniguchi, Chihiro Nakata, Hideo Kato, Mao Otake, Masahiro Umeda, Yuichiro Fuji, Eiji Nakagawa

{"title":"Anti-NMDAR Encephalitis With Serial Negative MRI Findings: An Evaluation Using Autoimmune Psychosis Criteria.","authors":"Satoshi Saito, Go Taniguchi, Chihiro Nakata, Hideo Kato, Mao Otake, Masahiro Umeda, Yuichiro Fuji, Eiji Nakagawa","doi":"10.1155/crnm/4561447","DOIUrl":"10.1155/crnm/4561447","url":null,"abstract":"Autoimmune psychosis criteria have been proposed for autoimmune encephalitis with prominent psychiatric symptoms as an alternative to biomarker-based diagnostic approaches such as the Graus criteria. We present a case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis that was initially misdiagnosed as a psychiatric disorder due to serial negative MRI findings and subsequently re-evaluated correctly using autoimmune psychosis criteria. A 15-year-old male developed sudden-onset generalized convulsive seizures that increased progressively in frequency and fluctuating psychiatric symptoms that gradually worsened to include reduced reactivity, language deterioration, and catatonia. On admission, both brain MRI and cerebral spinal fluid (CSF) findings were unremarkable; however, autoimmune encephalitis was strongly suspected based on autoimmune psychosis criteria and subsequently confirmed by detection of oligoclonal bands (OCBs) and anti-NMDAR antibodies in the serum and CSF. Repeated steroid pulse therapy resulted in significant clinical improvement. The patient met multiple autoimmune psychosis criteria, including subacute onset of psychiatric symptoms, catatonia, disproportionate cognitive dysfunction, decreased level of consciousness, and the emergence of seizures. These features are not typically present in primary psychiatric disorders. Anti-NMDAR encephalitis can present with a variety of symptoms, complicating its differentiation from primary psychiatric conditions. The application of autoimmune psychosis criteria may serve as a valuable diagnostic aid, particularly when MRI findings are repeatedly negative.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2025 ","pages":"4561447"},"PeriodicalIF":0.9,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Sentinel Oculomotor Nerve Palsy": A Harbinger of Subarachnoid Hemorrhage. 前哨动眼神经麻痹：蛛网膜下腔出血的先兆。

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Case Reports in Neurological Medicine Pub Date : 2025-05-13 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/6786272

Vijay Renga

引用次数: 0

Cerebellar Hemorrhage Masquerading as Unilateral Vestibulopathy: A Case Report. 小脑出血伪装成单侧前庭病变：1例报告。

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Case Reports in Neurological Medicine Pub Date : 2025-05-08 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/9611619

Thomas Zeyen, Thomas Klockgether, Christina Schaub, Daniel Paech, Timo Vogt, Delia Kurzwelly

引用次数: 0

Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review. 小儿甲型流感感染后慢性炎症性脱髓鞘性多神经病变：1例报告及文献复习。

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Case Reports in Neurological Medicine Pub Date : 2025-05-05 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/8840308

Emily Grew, Garrett Gianneschi, Janet Elgallab

引用次数: 0

Atypical Presentation of Susac Syndrome in 55-Year-Old: From Unremarkable Stroke Workup to Rapid Diagnosis of "Snowball Strokes" and Successful Immunosuppressive Treatment. 55岁Susac综合征的不典型表现：从无显著卒中检查到“雪球卒中”的快速诊断和成功的免疫抑制治疗。

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Case Reports in Neurological Medicine Pub Date : 2025-04-27 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/3178952

Yasaman Pirahanchi

引用次数: 0

Exploring Central Venous Thrombosis as a Rare Postinfectious Complication of Dengue: A Case Report. 中心静脉血栓形成作为一种罕见的登革热感染后并发症：1例报告。

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Case Reports in Neurological Medicine Pub Date : 2025-04-01 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/5368634

Linda Angela Mbah, Parvinder Kaur, Dakshin Meenashi Sundaram, Shubh Mehta, Zenia Elavia, Seyi Olaniyi, Jubran Al Balushi, Jeffrin John Varghese, Archit Kumar Nigam, Mansi Singh

{"title":"Exploring Central Venous Thrombosis as a Rare Postinfectious Complication of Dengue: A Case Report.","authors":"Linda Angela Mbah, Parvinder Kaur, Dakshin Meenashi Sundaram, Shubh Mehta, Zenia Elavia, Seyi Olaniyi, Jubran Al Balushi, Jeffrin John Varghese, Archit Kumar Nigam, Mansi Singh","doi":"10.1155/crnm/5368634","DOIUrl":"10.1155/crnm/5368634","url":null,"abstract":"Dengue fever, caused by a flavivirus transmitted through Aedes mosquitoes, presents a spectrum of clinical manifestations ranging from mild to severe. Several neurological complications, including encephalopathy and encephalitis, have been increasingly recognized. Here, we report a case of central venous thrombosis (CVT) as a postinfectious complication of dengue fever. A 38-year-old previously healthy male presented with classic dengue symptoms and later developed persistent headaches and visual disturbances. Neurological examination revealed papilledema, and imaging confirmed CVT involving the superior straight sinus. Prompt initiation of anticoagulant therapy led to gradual improvement in neurological symptoms and partial recanalization of the thrombosed sinus. Our case underscores the importance of considering thrombotic complications in dengue infections, despite the predominance of hemorrhagic manifestations. Understanding pathophysiology and appropriate management of thrombotic events in dengue fever is crucial for favorable patient outcomes.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2025 ","pages":"5368634"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11978471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biotinidase Deficiency: Report of a Tunisian Case With Neuromyelitis Optica-Like Presentation and Review of the Literature. 生物素酶缺乏：突尼斯一例光学样神经脊髓炎报告及文献复习。

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Case Reports in Neurological Medicine Pub Date : 2025-03-25 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/7003370

Abir Zioudi, Hanene Benrhouma, Maha Jamoussi, Thouraya Ben Younes, Zouhour Miladi, Hedia Klaa, Sonia Nagi, Brahim Tabarki, Ilhem Ben Youssef Turki, Ichraf Kraoua

引用次数: 0

Familial Reversible Cerebral Vasoconstriction Syndrome: Insights From Two Families. 家族性可逆性脑血管收缩综合征：来自两个家族的见解。

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Case Reports in Neurological Medicine Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.1155/crnm/3126513

Pacôme Constant Dit Beaufils, Benoît Guillon, Hugues Chabriat, Solène de Gaalon

引用次数: 0