Case Reports in Neurological Medicine最新文献_第10页

Ominous Occurrence of Spinal Intradural Primary Malignant Peripheral Nerve Sheath Tumor Four Decades following Radiation Therapy for Testicular Seminoma. 睾丸精原细胞瘤放射治疗40年后脊髓硬膜内原发性恶性周围神经鞘肿瘤的发生。

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Case Reports in Neurological Medicine Pub Date : 2020-01-27 eCollection Date: 2020-01-01 DOI: 10.1155/2020/1792582

Osmond C Wu, Berje H Shammassian, Arunit J S Chugh, Aparna Harbhajanka, Manish K Kasliwal

引用次数: 4

Conversion Disorder: Early Diagnosis and Personalized Therapy Plan Is the Key. 转换障碍:早期诊断和个性化治疗方案是关键。

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Case Reports in Neurological Medicine Pub Date : 2020-01-10 eCollection Date: 2020-01-01 DOI: 10.1155/2020/1967581

Lauren Miller, Robert L Archer, Nidhi Kapoor

引用次数: 5

Intravascular Lymphoma with Progressive CNS Hemorrhage and Multiple Dissections. 伴有进行性中枢神经系统出血和多发夹层的血管内淋巴瘤。

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Case Reports in Neurological Medicine Pub Date : 2020-01-10 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6134830

Ricky Chen, Gurjeet Singh, J Scott McNally, Cheryl A Palmer, Adam de Havenon

{"title":"Intravascular Lymphoma with Progressive CNS Hemorrhage and Multiple Dissections.","authors":"Ricky Chen, Gurjeet Singh, J Scott McNally, Cheryl A Palmer, Adam de Havenon","doi":"10.1155/2020/6134830","DOIUrl":"https://doi.org/10.1155/2020/6134830","url":null,"abstract":"Introduction: Intravascular lymphoma (IVL) is an uncommon and often fatal disease characterized by intraluminal proliferation of lymphomatous cells within blood vessels. Because of a heterogeneous clinical presentation and lack of sensitive diagnostic protocols, diagnosis of IVL is most often made at autopsy. However, with early diagnosis and appropriate chemotherapy, the prognosis is greatly improved and complete remission is possible. In order to broaden the possible presentations of IVL, we present a patient with an atypical manifestation of biopsy-proven intravascular large B-cell lymphoma who suffered dissections of both intracranial and extracranial arteries in addition to progressive intracranial hemorrhages. Case Report. A 47-year-old woman presented with unilateral paresthesias. She developed progressive multifocal infarcts and hemorrhage with dissections of both intracranial and extracranial arteries, resulting in coma. Brain biopsy revealed IVL. She received aggressive chemotherapy and remains in complete remission with good neurologic recovery.Conclusion: IVL is known to exert its pathology on small arteries and capillaries, but is not known to cause dissections of large vessels. The diagnosis should be considered in cases with unexplained arterial dissections and progressive strokes. Early diagnosis with appropriate laboratory screening and tissue confirmation by biopsy can lead to greatly improved outcomes.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2020 ","pages":"6134830"},"PeriodicalIF":0.9,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/6134830","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38052549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Anti-NMDAR Encephalitis: Higher Suspicious Needed for Earlier Diagnosis (Case Report, Literature Review and Diagnostic Criteria). 抗nmdar脑炎:早期诊断需高度怀疑(病例报告、文献复习及诊断标准)。

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Case Reports in Neurological Medicine Pub Date : 2019-12-28 eCollection Date: 2019-01-01 DOI: 10.1155/2019/7476254

Chanaka Amugoda, Noushin Chini Foroush, Hamed Akhlaghi

{"title":"Anti-NMDAR Encephalitis: Higher Suspicious Needed for Earlier Diagnosis (Case Report, Literature Review and Diagnostic Criteria).","authors":"Chanaka Amugoda, Noushin Chini Foroush, Hamed Akhlaghi","doi":"10.1155/2019/7476254","DOIUrl":"https://doi.org/10.1155/2019/7476254","url":null,"abstract":"Background: Auto-immune mediated anti-NMDA receptor encephalitis is a very common delayed diagnosed encephalitis which predominately affecting young population.Objectives: This encephalitis is relatively unknown amongst emergency physicians and a majority of patients are admitted to psychiatric wards before their diagnosis is confirmed and appropriate treatments are commenced. We reported a case of a 22-year-old female presented to our emergency department with acute psychiatric symptoms. She was initially diagnosed with first presentation of acute psychosis and was hospitalised under mental health act. further assessment in the emergency department identified possible an organic cause for her acute psychosis and she was later admitted under medical team after her mental health assessment order was revoke. Several days later, her CSF result was positive with anti-NMDA receptor anti-bodies. Appropriate treatments were instituted leading to her full recovery.Conclusion: This case was the first confirmed anti-NMDA receptor encephalitis in our emergency department. It highlights the importance of thorough assessment of psychiatric presentations to emergency departments and consideration of auto-immune medicated encephalitis as one of the differential diagnosis in young patients presenting with first acute psychotic episode.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2019 ","pages":"7476254"},"PeriodicalIF":0.9,"publicationDate":"2019-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/7476254","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37557879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

A Case Report of Extensive Cerebral Venous Sinus Thrombosis as a Presenting Sign of Relapsing Nephrotic Syndrome. 广泛脑静脉窦血栓形成为复发性肾病综合征的表现。

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Case Reports in Neurological Medicine Pub Date : 2019-12-27 eCollection Date: 2019-01-01 DOI: 10.1155/2019/6840240

Janet K Lee, Kathleen Murray, Swetha Renati

{"title":"A Case Report of Extensive Cerebral Venous Sinus Thrombosis as a Presenting Sign of Relapsing Nephrotic Syndrome.","authors":"Janet K Lee, Kathleen Murray, Swetha Renati","doi":"10.1155/2019/6840240","DOIUrl":"https://doi.org/10.1155/2019/6840240","url":null,"abstract":"Nephrotic syndrome is defined by three characteristic features including proteinuria of >3 g in 24 hours, hypoalbuminemia of less than 3 g/dL, and peripheral edema. Multiple nephropathies can result in nephrotic syndrome. Most commonly, minimal change disease is seen in children under the age of 10, while adults are more commonly found to have membranous nephropathy. Hypercoagulability and thrombotic sequela can be seen in nephrotic syndrome, regardless of underlying etiology, and thrombosis is most commonly seen in deep veins of the lower extremities and renal veins. Our case identifies an adult with previously diagnosed and treated for minimal change disease who presented with weight gain, peripheral edema, foamy urine, headache but no neurologic deficits. The patient was found to have near to complete occlusion of the entire superior sagittal sinus, near complete occlusion of the left transverse and sigmoid sinuses, and nonocclusive thrombus in the right sigmoid sinus. She was treated with heparin and IV steroids then transitioned to warfarin and PO steroids, respectively, with resolution of symptoms. This case report emphasizes on the importance of recognizing CVST as a potential complication of nephrotic syndrome at both initial presentation and relapse.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2019 ","pages":"6840240"},"PeriodicalIF":0.9,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/6840240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37554268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

MELAS Missed for Years: Stroke-Like Lesions Are No Indication for Brain Biopsy. MELAS被遗漏多年:脑卒中样病变没有脑活检的迹象。

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Case Reports in Neurological Medicine Pub Date : 2019-12-27 eCollection Date: 2019-01-01 DOI: 10.1155/2019/9312451

J Finsterer

引用次数: 1

Mitochondrial Neurogastrointestinal Encephalomyopathy: Novel Pathogenic Mutation in Thymidine Phosphorylase Gene in a Patient from Cape Verde Islands. 线粒体神经胃肠道脑肌病:佛得角群岛患者胸苷磷酸化酶基因的新致病性突变。

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Case Reports in Neurological Medicine Pub Date : 2019-12-11 eCollection Date: 2019-01-01 DOI: 10.1155/2019/5976410

Catarina Falcão de Campos, Miguel Oliveira Santos, Rafael Roque, Isabel Conceição, Mamede de Carvalho

{"title":"Mitochondrial Neurogastrointestinal Encephalomyopathy: Novel Pathogenic Mutation in Thymidine Phosphorylase Gene in a Patient from Cape Verde Islands.","authors":"Catarina Falcão de Campos, Miguel Oliveira Santos, Rafael Roque, Isabel Conceição, Mamede de Carvalho","doi":"10.1155/2019/5976410","DOIUrl":"https://doi.org/10.1155/2019/5976410","url":null,"abstract":"Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE) is a rare autosomal recessive disorder caused by mutations in the gene encoding the Thymidine Phosphorylase (TP). It is clinically characterized by severe gastrointestinal dysmotility, cachexia, palpebral ptosis, ophthalmoparesis, sensorimotor polyneuropathy and leukoencephalopathy. The diagnosis is established by the presence of typical clinical and neuroimaging features, positive family history, and abnormal genetic test. A 19-year-old Cape Verdean patient with a history since childhood of recurrent episodes of nausea, vomiting, diarrhoea and painful abdominal distension associated with progressive motor disability with difficulty in climbing stairs and running and clumsiness with her hands. The diagnostic workup was suggestive of MNGIE. Genetic screening of the TYMP gene identified a novel mutation (c. 1283 G>A). Patients with MNGIE have significant comorbidity and mortality, and they are frequently misdiagnosed. A better acknowledgment of this disorder is essential to permit an earlier diagnosis and to improve disease management.","PeriodicalId":9615,"journal":{"name":"Case Reports in Neurological Medicine","volume":"2019 ","pages":"5976410"},"PeriodicalIF":0.9,"publicationDate":"2019-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/5976410","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37499868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Duodenal Neuroendocrine Tumour Presenting as GABA B Receptor Autoimmune Encephalitis. 十二指肠神经内分泌肿瘤表现为GABA B受体自身免疫性脑炎。

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Case Reports in Neurological Medicine Pub Date : 2019-12-06 eCollection Date: 2019-01-01 DOI: 10.1155/2019/3428918

Dhanashree Peddawad, Manoj K Singh

引用次数: 0

Successful Pallidal Deep Brain Stimulation Treatment in a Case of Generalized Dystonia due to a Novel ANO3 Mutation. 一种新的ANO3突变导致的广泛性肌张力障碍的成功的苍白深部脑刺激治疗。

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Case Reports in Neurological Medicine Pub Date : 2019-11-29 eCollection Date: 2019-01-01 DOI: 10.1155/2019/3154653

Lizl Lasky, Lindsay Bliss, Christos Sidiropoulos

引用次数: 5

Nilotinib-Induced Dystonia and Cognitive Deficits in a Neurologically Normal Patient with Chronic Myeloid Leukemia 尼洛替尼诱导的神经功能正常的慢性髓性白血病患者肌张力障碍和认知缺陷