Maria Gergoudis, Logan Laubach, Glenn E Lee, Jeffrey R Donowitz
{"title":"De Quervain's Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report.","authors":"Maria Gergoudis, Logan Laubach, Glenn E Lee, Jeffrey R Donowitz","doi":"10.1155/crdi/5117572","DOIUrl":"10.1155/crdi/5117572","url":null,"abstract":"<p><p>We present the case of a fully vaccinated 39-year-old male with no pertinent past medical history who initially presented with De Quervain's tenosynovitis which was successfully treated with a corticosteroid injection. His symptoms recurred during a COVID-19 infection, which was treated with a repeat corticosteroid injection. Symptoms recurred during an influenza infection and were subsequently treated with a first dorsal compartment release. The etiology of De Quervain's tenosynovitis remains unclear. It has classically been categorized as a noninflammatory degenerative process, but recent evidence suggests a possible inflammatory connection. Here, we present a case of recurrent De Quervain's tenosynovitis exacerbated by two distinct viral infections. We hypothesize that viral-induced systemic inflammation led to localized recurrence of inflammation within the tendon sheath. Further studies including cytokine analysis and inflammatory markers are needed to advance this hypothesis.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"5117572"},"PeriodicalIF":1.0,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Mirza, John Erikson Yap, Rajan Kapoor, Imran Gani
{"title":"Manifestation of Cytomegalovirus-Associated Gastritis and Colitis With Immunosuppression and Review of Literature.","authors":"Ahmad Mirza, John Erikson Yap, Rajan Kapoor, Imran Gani","doi":"10.1155/crdi/1143576","DOIUrl":"10.1155/crdi/1143576","url":null,"abstract":"<p><p>Cytomegalovirus (CMV) infection in immunocompromised patients can cause significant morbidity and mortality. Early recognition and treatment helps to improve outcome. We present a case of postrenal transplant CMV infection causing both upper and lower gastrointestinal infection and symptoms. Patient developed significant co-morbidity which required multiple hospital admissions and therapeutic interventions.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"1143576"},"PeriodicalIF":1.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report of <i>Chlamydia psittaci</i> Infective Endocarditis Complicated With Pneumonia.","authors":"Dongmei Zhao, Li Zhang, Qiulin Sun, Jun Cheng","doi":"10.1155/crdi/7536462","DOIUrl":"10.1155/crdi/7536462","url":null,"abstract":"<p><p>Psittacosis is a zoonotic disease caused by <i>Chlamydia psittaci</i> and is commonly found in birds and poultry. Human infection is uncommon, and most cases are sporadic. Infection of extrapulmonary organs by <i>Chlamydia psittaci</i> is extremely rare. A rare case of infective endocarditis complicated by pneumonia caused by <i>Chlamydia psittaci</i> was reported, which was diagnosed using metagenomic next-generation sequencing (mNGS). The patient recovered after receiving appropriate anti-infective treatment. Discussion on the pathogenesis, diagnosis, and treatment of this disease based on recent literature reports aimed to improve the prognosis of similar patients and enhance the understanding of clinicians.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"7536462"},"PeriodicalIF":1.0,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Tuggle, Alison I Orvin, Christian Caveness, Christopher Ingram
{"title":"An Incidental Finding of Whipple's Disease Masquerading as Nonspecific, Long-Standing Symptoms.","authors":"Thomas Tuggle, Alison I Orvin, Christian Caveness, Christopher Ingram","doi":"10.1155/crdi/3177799","DOIUrl":"https://doi.org/10.1155/crdi/3177799","url":null,"abstract":"<p><p>Whipple's disease is a rare bacterial infection that is often present for years prior to diagnosis. Symptoms are nonspecific in the early stages of presentation and are primarily gastrointestinal in nature. The disease may progress with more systemic symptoms including arthralgia, fever, lymphadenopathy, cardiovascular disease, and central nervous system involvement. This case describes a man with a history of long-standing, nonspecific symptoms who only began to show significant improvement after an incidental finding of Whipple's disease. Due to its rare nature, other instances of the disease have likely gone undiagnosed. A brief review of relevant literature is also included.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2024 ","pages":"3177799"},"PeriodicalIF":1.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgios Kravvas, Nada Aboukhatwah, Lola Meghoma, Victoria Vilenchik, Jon Oxley, Daniel Keith
{"title":"A Novel, Nonaquatic Zoonotic Transmission of <i>Mycobacterium marinum</i>.","authors":"Georgios Kravvas, Nada Aboukhatwah, Lola Meghoma, Victoria Vilenchik, Jon Oxley, Daniel Keith","doi":"10.1155/crdi/2767290","DOIUrl":"https://doi.org/10.1155/crdi/2767290","url":null,"abstract":"<p><p><b>Introduction:</b> <i>Mycobacterium marinum</i> was first described in humans in 1954, known to infect fish species and contaminate water and fish products. Inoculation to humans occurs through injured skin resulting in the formation of a solitary nodule known as \"fish tank granuloma.\" Disseminated infections have been reported in the immunocompromised and can present with extracutaneous manifestations such as arthritis and osteomyelitis. Nonaquatic transmission has not been previously reported. <b>Case Presentation:</b> A 63-year-old lady with rheumatoid arthritis and bronchiectasis was referred to dermatology with widespread soft dermal plaques, pustules, erosions, and necrotic wounds. Multiple bacterial and viral swabs were negative. A biopsy was performed that showed a neutrophilic dermatosis suggestive of Sweet's Syndrome. The patient initially improved with prednisolone, but subsequently deteriorated with a worsening rash, joint pains, and neutropenic sepsis. Repeat biopsies eventually revealed abundant acid-fast bacilli, later confirmed to be <i>Mycobacterium marinum</i>. Our patient had no history of exposure to aquatic organisms but had previously cared for an inland bearded dragon with an unknown illness. Although infection with <i>M. marinum</i> has been reported in reptiles, cases of nonaquatic zoonotic transmission have not been described in the literature. <b>Conclusion:</b> <i>Mycobacterium marinum</i> infection should be considered in patients with indicative clinical and histological features, especially in the immunocompromised, even in the absence of an obvious aquatic source of infection. Awareness of this entity could lead to earlier diagnoses and reduced morbidity and mortality.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2024 ","pages":"2767290"},"PeriodicalIF":1.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lemierre's Syndrome Due to <i>Klebsiella pneumoniae</i> Results in Pulmonary Abscess Complications in a Patient With Diabetes: A Rare Case Report.","authors":"Trung Dinh Ngo, Cuong Thai Nguyen, Nam Ho","doi":"10.1155/crdi/8176530","DOIUrl":"10.1155/crdi/8176530","url":null,"abstract":"<p><p><b>Background:</b> Lemierre's syndrome (LS), first described by Andre Lemierre in the early 20th century, is a rare but potentially life-threatening condition typically caused by <i>Fusobacterium necrophorum</i>. However, recent literature has reported cases of LS caused by various other bacteria, including <i>Klebsiella pneumoniae</i>. In this report, we present a rare case of LS in a patient with diabetes caused by <i>K. pneumoniae</i>. <b>Case Report:</b> A 62-year-old Vietnamese male with a history of type 2 diabetes mellitus, presented with an 8-day history of progressive left neck swelling, fever, dysphagia, odynophagia, and reduced appetite. Despite initial antibiotic therapy, his condition deteriorated, leading to pulmonary abscesses and septic shock. Abscess content culture revealed K. pneumoniae. The patient required intubation, mechanical ventilation, and surgical drainage of the neck abscess. Treatment with meropenem, along with glycemic control, led to clinical improvement. The patient was subsequently extubated, achieved complete wound healing, and was discharged with normal biochemical parameters. <b>Conclusion:</b> This case highlights that LS can be caused by pathogens not initially outlined by Andre Lemierre, such as <i>K. pneumoniae</i>. Clinicians should consider a broader spectrum of causative organisms when there is a strong clinical suspicion of LS and adjust antimicrobial coverage accordingly. The association between <i>K. pneumoniae</i>-related LS and diabetes mellitus warrants further investigation, as current evidence suggests that diabetes may predispose patients to this particular pathogen.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2024 ","pages":"8176530"},"PeriodicalIF":1.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11685315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando S da Silveira, Rafael Brito Foureaux Ribeiro, Sandra Lucia Branco Mendes Coutinho, Evelin Soares de Brito, Jacques F Meis, Marcela Santos Corrêa da Costa, Julival Fagundes Ribeiro, Tazio Vanni
{"title":"Mucormycosis Causing Splenic Infarction, Gastric Fistula, and Brain Abscess in a Patient With Acute Myeloid Leukemia: A Case Report.","authors":"Fernando S da Silveira, Rafael Brito Foureaux Ribeiro, Sandra Lucia Branco Mendes Coutinho, Evelin Soares de Brito, Jacques F Meis, Marcela Santos Corrêa da Costa, Julival Fagundes Ribeiro, Tazio Vanni","doi":"10.1155/crdi/4079965","DOIUrl":"10.1155/crdi/4079965","url":null,"abstract":"<p><p>Invasive mucormycosis is an aggressive fungal infection characterized by rapid progression, primarily impacting immunocompromised individuals. Herein, we report a case of splenic infarction in association with gastrointestinal fistula and brain abscess as a rare presentation of mucormycosis biopsy, proven in a 56-year-old patient diagnosed with acute myeloid leukemia. The patient initially sought medical attention with a 3-week history of fever, night sweats, and malaise. Considering the chest computed tomography findings compatible with fungal disease and neutropenia, he underwent broad-spectrum antifungal therapy. Following the occurrence of splenic infarctions and a gastric fistula, the patient underwent a partial gastrectomy and splenectomy. Despite the interventions, the patient did not have a successful outcome and died on the second postoperative day. This case highlights the importance of timely suspicion, immediate antifungal therapy, and surgical intervention to improve the survival prospects of patients with multifaceted manifestations of mucormycosis.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2024 ","pages":"4079965"},"PeriodicalIF":1.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11669425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142892276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Two Cases of Maggot-Associated <i>Ignatzschineria</i> Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat.","authors":"Erin Pomerantz, Olivia Pericak, Carly Sokach, Jocelyn Edathil, Ho-Man Yeung","doi":"10.1155/crdi/7684187","DOIUrl":"10.1155/crdi/7684187","url":null,"abstract":"<p><p>The city of Philadelphia has seen an increase in homelessness and substance use disorders, often associated with xylazine-contaminated opiates. Here, we report the first two cases of wound infection and bacteremia associated with the Gram-negative rod <i>Ignatzschineria</i> species. Both cases were associated with maggot colonization in chronic lower extremity wounds from fentanyl/xylazine injections. Poor living conditions and lack of wound care are central to both case presentations. We believe this organism to be an emerging medical threat associated with injection drug use, xylazine-associated wounds, and homelessness which may impact future treatment options in this patient population. This report underscores the emergence of <i>Ignatzschineria</i> bacteremia in individuals with a history of xylazine-associated wounds and substance use disorder. Successful management should prioritize wound care and adherence to antibiotic regimens to prevent complications in these challenging cases.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2024 ","pages":"7684187"},"PeriodicalIF":1.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahnaz Arian, Ali Tajik, Mohammad Abbasi Tashnizi, Abdul Rahman Alizada
{"title":"A Misdiagnosis of Brucellosis Leads to Prosthetic Valve Endocarditis Complicated by Cerebrovascular Accident.","authors":"Mahnaz Arian, Ali Tajik, Mohammad Abbasi Tashnizi, Abdul Rahman Alizada","doi":"10.1155/crdi/7361317","DOIUrl":"10.1155/crdi/7361317","url":null,"abstract":"<p><p>Cardiovascular complications of Brucellosis are not common and affecting less than 2% of cases. In clinical practice, endocarditis is the most frequent cardiovascular complication and is responsible for most of the brucellosis-related mortality cases and usually diagnosed lately in the course of the disease with mostly aorta valve involvement. In this case report, we present the case of a 27-year-old woman who was admitted to the hospital with fever, sudden onset right side hemiparesis, and horizontal gaze palsy. During the stroke work up, she underwent cardiac evaluation, including echocardiography with susceptibility to septic emboli with cardiac origin, and the result indicates presence of vegetations on prosthetic aortic valve suggestive of infective endocarditis. Hopefully our patient responded well to combination of heart surgery and antibrucellosis regimen and was finally discharged with stable general condition. It is important to raise awareness of this rare but potentially serious complication of brucellosis, especially in the endemic area, and to emphasize the value of early diagnosis and treatment.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2024 ","pages":"7361317"},"PeriodicalIF":1.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge A Caceda, Afshan Iqbal, Kristy Bono, Diana Finkel, Eli Goshorn
{"title":"Tick Tock-A Matter of Time: Two Cases of Babesia Acquired in Urban Newark, NJ.","authors":"Jorge A Caceda, Afshan Iqbal, Kristy Bono, Diana Finkel, Eli Goshorn","doi":"10.1155/2024/3912571","DOIUrl":"10.1155/2024/3912571","url":null,"abstract":"<p><p>Babesiosis is a parasitic tick-borne infectious disease that is well elucidated in medical literature and known to be endemic to the Midwest and northeast United States. However, like other infectious diseases, its epidemiology is subject to change. This case report documents two cases with clinical presentations that deviate from what is expected in typical cases of Babesiosis. Two patients presented to a safety-net hospital in Newark, NJ, during the summer of 2022 with nonspecific symptoms. The first patient had a history of polysubstance use disorder and presented with bilateral leg pain, drowsiness, exertional dyspnea, back pain, and chest pain. The second patient had recently returned from a trip to Guatemala and presented with subjective fevers, generalized myalgias, malaise, headaches, and chills. Both patients underwent similar workups yielding a diagnosis of Babesiosis. Of note, neither patient had recently spent time in wooded areas. Ultimately, both patients were treated for Babesiosis with resolution of their presenting symptoms. These two cases suggest that the epidemiology of Babesiosis is changing and provide a clinical workflow for diagnosing and managing this disease in a modern healthcare setting.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2024 ","pages":"3912571"},"PeriodicalIF":1.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}