Case Reports in Infectious Diseases最新文献_第2页

Aerococcus urinae Spondylodiscitis: A Case Report and Review of the Literature. 尿气球菌性脊柱炎1例报告及文献复习。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-28 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/1569042

Suranthaniy S Sivalingam, Virginie Prendki, Nicolas Garin

{"title":"Aerococcus urinae Spondylodiscitis: A Case Report and Review of the Literature.","authors":"Suranthaniy S Sivalingam, Virginie Prendki, Nicolas Garin","doi":"10.1155/crdi/1569042","DOIUrl":"10.1155/crdi/1569042","url":null,"abstract":"Background: Aerococcus urinae, a rare human pathogen, mainly causes urinary tract infection, endocarditis, and bacteremia. However, it is rarely the cause of other types of infection such as spondylodiscitis. Invasive A. urinae infection chiefly occurs in older men with underlying urinary tract disorders. The real incidence may be underestimated, as Aerococci grow in a CO2-containing atmosphere, and urine cultures are usually not incubated in this environment. There have been eight case reports of spondylodiscitis due to A. urinae. Material and Methods: We report a 9th case occurring in an 80-year-old Caucasian man with lower back pain. The patient had predisposing conditions (diabetes and a history of urological surgery). Spinal MRI showed signs of spondylodiscitis. Two computed tomography-guided biopsies targeting the intervertebral disc and psoas muscle were not diagnostic. One of 10 blood culture bottles grew A. urinae. Results: After worsening of an L2 fracture, and unsuccessful percutaneous sampling procedures, the patient underwent surgical stabilization of T12 to L4 with multiple biopsies. Biopsy cultures grew Aerococcus urinae. Amoxicillin was administered intravenously for 14 days, followed by oral levofloxacin for 3 months. Conclusion: A. urinae should be considered in spondylodiscitis with negative cultures, particularly in older men with diabetes and urological conditions.","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"1569042"},"PeriodicalIF":0.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disseminated Infection With Mycobacterium genavense in the Setting of HIV Infection Misdiagnosed as Sarcoidosis. 在HIV感染被误诊为结节病的背景下弥散性属支杆菌感染。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-24 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/2249985

Alireza Eskandari, Mitra Rezaei, Minoosh Shabani, Mihan Pourabdoullah, Afshin Moniri, Majid Marjani

引用次数: 0

Amoebic Liver Abscesses in Returning Travelers: Lessons to Keep in Mind From a Nonendemic Area. 归国旅行者的阿米巴肝脓肿：从非流行地区吸取的教训。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-21 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/9933233

Anna Barbiero, Sasha Trevisan, Tommaso Manciulli, Jessica Mencarini, Annalisa Cavallo, Costanza Fiorelli, Alessandro Bartoloni, Michele Spinicci, Lorenzo Zammarchi

引用次数: 0

Paradoxical Reactions of Central Nervous System Tuberculosis: Report of Three Immunocompetent Cases. 中枢神经系统结核的矛盾反应：三例免疫正常病例报告。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-21 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/5416948

Eduardo Mariño, Jorge Rodríguez-Pardo, Laura Vidal, Gerardo Zmork, Alicia Garcial-Leal, Beatriz Díaz-Pollán, Laura Lacruz

{"title":"Paradoxical Reactions of Central Nervous System Tuberculosis: Report of Three Immunocompetent Cases.","authors":"Eduardo Mariño, Jorge Rodríguez-Pardo, Laura Vidal, Gerardo Zmork, Alicia Garcial-Leal, Beatriz Díaz-Pollán, Laura Lacruz","doi":"10.1155/crdi/5416948","DOIUrl":"10.1155/crdi/5416948","url":null,"abstract":"Introduction: Paradoxical reactions during tuberculosis (TBC) therapy are characterized by clinical or radiological worsening of preexisting tuberculous lesions or the appearance of new manifestations following appropriate TBC treatment. Identifying this phenomenon is crucial, since it can be mistaken with treatment failure or relapse. Although widely described in HIV patients following immune reconstitution inflammatory syndrome, the literature on HIV-negative patients is scarce. Case Series: We present three cases of immunocompetent patients with central nervous system tuberculosis (CNS-TBC) who developed paradoxical reactions following appropriate TBC therapy. These included diverse clinical and radiological manifestations, such as persistent headaches, apparition or progression of tuberculomas, cerebral infarcts, and dorsal myelitis. Paradoxical reactions occurred within an average of 2.5 months from the start of anti-TBC treatment. Conclusion: Our findings underscore the importance of closely monitoring patients following anti-TBC treatment to identify potential complications rapidly. Paradoxical reactions due to exaggerated immune response to Mycobacterium tuberculosis complex antigens should be considered in a thorough differential diagnosis including other CNS infections, granulomatous or neoplastic disorders, treatment failure, or treatment-related toxicities. Ensuring adequate adherence to anti-TBC treatment and immunosuppressants is essential in such cases.","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"5416948"},"PeriodicalIF":0.8,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurosyphilis Presenting as Sleep Disorder and Muscle Soreness Complicated With HIV Infection: A Case Report. 以睡眠障碍和肌肉酸痛伴HIV感染为表现的神经梅毒1例报告

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-18 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/4758423

Shu-Qi Yang, Hua-Tang Zhang, Yi-Jie Lin, Xing Wang, Yan-Yan Qiu, Xue-Ping Yu

引用次数: 0

Corrigendum to "Cardioembolic Stroke Due to Prosthetic Valve Endocarditis Caused by Candida parapsilosis: A Case Report". “假丝酵母菌旁瓣病致人工瓣膜心内膜炎致心脏栓塞性中风1例报告”的更正。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-18 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/9872490

引用次数: 0

Isolated Facial Vein Thrombophlebitis Caused by Fusobacterium nucleatum: A Lemierre-Variant Case. 由核梭杆菌引起的孤立面静脉血栓性静脉炎：一例莱米尔变异病例。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/9938125

Nicole Oska, Deni Peterson, Kendall Brothers, Ragamayi Maramraju, Asem Ayyad, Brianna Hohmann

{"title":"Isolated Facial Vein Thrombophlebitis Caused by Fusobacterium nucleatum: A Lemierre-Variant Case.","authors":"Nicole Oska, Deni Peterson, Kendall Brothers, Ragamayi Maramraju, Asem Ayyad, Brianna Hohmann","doi":"10.1155/crdi/9938125","DOIUrl":"10.1155/crdi/9938125","url":null,"abstract":"Background: Lemierre's syndrome is an uncommon yet potentially fatal infection, classically secondary to bacterial pharyngeal infections. It is typically characterized by bacteremia, most frequently due to Fusobacterium necrophorum and internal jugular vein thrombophlebitis. If untreated, septic embolization may result, potentially damaging the lungs, liver, brain, or other organs. This report describes a variant of Lemierre's syndrome in a young woman with streptococcal pharyngitis, who developed Fusobacterium nucleatum bacteremia and isolated facial vein thrombophlebitis, highlighting the importance of early diagnosis and treatment. Case Presentation: A 33-year-old woman with no significant past medical history presented with sore throat, chills, and right-sided facial and neck pain. Initially diagnosed with streptococcal pharyngitis at an urgent care clinic, she presented to the emergency department soon afterwards due to the development of severe rigors and fever. Blood cultures revealed growth of Fusobacterium nucleatum, raising suspicion for Lemierre's syndrome in the setting of worsening facial and neck pain despite negative initial imaging of the soft tissue of the neck. A subsequent CT venogram confirmed isolated thrombosis of the right facial vein. The patient was treated and discharged in stable condition on a 4 week course of metronidazole and 2 weeks of ceftriaxone. Conclusion: This case emphasizes the importance of maintaining suspicion for Lemierre's syndrome in patients with bacterial pharyngitis, especially when atypical symptoms such as facial pain occur. Although the internal jugular vein is most commonly affected, facial vein thrombosis may also occur. Early antibiotic treatment is critical for preventing severe complications including septic shock and embolization.","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"9938125"},"PeriodicalIF":0.8,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the Lungs: A Rare Case of Extrapulmonary Tuberculosis Presenting With Neck Vein Thrombosis and Seizure. 肺外：一例罕见的肺外结核并发颈静脉血栓和癫痫。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-13 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/4888774

Hamda Al-Mansoori, M Z Sharaf Eldean, Abdelkareem Alhyari, Mahmoud Tabouni

{"title":"Beyond the Lungs: A Rare Case of Extrapulmonary Tuberculosis Presenting With Neck Vein Thrombosis and Seizure.","authors":"Hamda Al-Mansoori, M Z Sharaf Eldean, Abdelkareem Alhyari, Mahmoud Tabouni","doi":"10.1155/crdi/4888774","DOIUrl":"10.1155/crdi/4888774","url":null,"abstract":"Introduction: Tuberculosis (TB), caused by Mycobacterium tuberculosis, primarily affects the lungs but can involve virtually any organ system, manifesting as extrapulmonary TB. While TB-related hypercoagulability and venous thromboembolism are recognized, such presentations remain uncommon and diagnostically challenging, especially in the absence of classical symptoms. Case Presentation: We report the case of a 24-year-old immunocompetent female who initially presented with painless right-sided neck swelling. Imaging revealed an acute thrombus in the right internal jugular vein (IJV), with no clear underlying cause. Further evaluation showed enlarged necrotic mediastinal lymph nodes, raising suspicion for lymphoma. However, the patient later developed a seizure episode, and subsequent neuroimaging revealed multiple intracranial ring-enhancing lesions. Ultimately, mediastinoscopic lymph node biopsy confirmed necrotizing granulomatous inflammation, with a positive TB polymerase chain reaction (PCR), consistent with disseminated TB involving both vascular and central nervous systems. The patient was started on antitubercular therapy, anticoagulation, and adjunctive corticosteroids, with multidisciplinary follow-up arranged. Discussion: This case highlights TB-induced hypercoagulability as a potential cause of isolated venous thrombosis and underscores the diagnostic challenges when TB mimics malignancy. It also emphasizes the importance of considering TB in the differential diagnosis of unexplained thrombosis and intracranial lesions, even in the absence of pulmonary symptoms. Conclusion: Clinicians should maintain a high index of suspicion for extrapulmonary TB in atypical thrombotic events. Early tissue diagnosis and a multidisciplinary approach are key to effective management and favorable outcomes.","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"4888774"},"PeriodicalIF":0.8,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complicated Pediatric Pneumonia With Eikenella Caused by Foreign Body Aspiration: Institutional and Literature Review. 异物吸入引起的复杂儿童肺炎并艾肯菌：机构和文献综述。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-11 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/2857930

Leon Joseph, Marc Assous, Karin Dreifuss, Shmuel Goldberg, Elie Picard

引用次数: 0

Linezolid-Induced Glossitis and Papillitis in Orthopedic Patients With Postoperative Infection: A Case Report. 骨科术后感染患者利奈唑胺致舌炎和乳头炎1例。

IF 0.8

Case Reports in Infectious Diseases Pub Date : 2025-08-10 eCollection Date: 2025-01-01 DOI: 10.1155/crdi/9036606

Ryan J Blake, Benjamin M Frye, Allison M Lastinger

{"title":"Linezolid-Induced Glossitis and Papillitis in Orthopedic Patients With Postoperative Infection: A Case Report.","authors":"Ryan J Blake, Benjamin M Frye, Allison M Lastinger","doi":"10.1155/crdi/9036606","DOIUrl":"10.1155/crdi/9036606","url":null,"abstract":"Linezolid, an oxazolidinone antibiotic, is commonly used to treat Gram-positive skin infections and has additional off-label success in treating bone and soft tissue infections. Linezolid has been associated with adverse effects, particularly those that are hematologic and neurologic in nature. However, we present three orthopedic patients who developed oral pain and swelling of the circumvallate papillae after a 10-day course of linezolid therapy, without the characteristic color changes associated with black hairy tongue as previously reported in the literature. All three patients were treated for superficial infections, and none exhibited signs of drug toxicity or neutropenia. Adverse side effects emerged despite short-term linezolid use, contrasting with previously reported cases involving long-term therapy. While black hairy tongue has been associated with linezolid and other antibiotics, these cases represent the first reported instance of generalized glossitis and papillitis without discoloration or noticeable alterations in the anterior portions of the tongue. The absence of coinfections or concurrent medications likely to cause similar symptoms suggests a unique set of side effects potentially correlated with linezolid. This case series emphasizes the importance of monitoring for atypical oral symptoms in patients on short-term linezolid therapy and adds to the growing body of literature on the side-effect profile. Further investigation into the mechanism of these reactions is necessary to better guide clinical practice in managing antibiotic-related oral adverse effects.","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"9036606"},"PeriodicalIF":0.8,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0