Antibiotic-Resistant Shigella sonnei Bacteremia in an Immunocompetent Postgastric Bypass Patient Without Typical Risk Factors.

Shigella bacteremia, though rare, is a serious condition that highlights the importance of recognizing potential complications in patients with Shigella infections. In this paper, we present a case of Shigella bacteremia in a 53-year-old female s/p a Roux-en-Y gastric bypass revision four months prior, presenting with acute onset of nausea, vomiting, and persistent, explosive, watery diarrhea which started one day after she consumed pork chops and ground beef. Initial laboratory tests indicated leukocytosis and hypokalemia. Human immunodeficiency virus (HIV), rapid plasma regain (RPR), and Hepatitis C were nonreactive. A computed tomography (CT) scan of the abdomen and pelvis showed no intestinal wall thickening or any other acute abnormalities. Blood cultures identified a Shigella sonnei infection that was resistant to multiple antibiotics. She was treated with intravenous meropenem. Shigella bacteremia is a rare complication of Shigella infection and requires thorough investigation to identify potential underlying factors. Antibiotic susceptibilities should also be assessed, given the increasing resistance of Shigella strains to previously effective treatments.