Case Reports in Infectious Diseases最新文献

{"title":"Concurrent Middle Ear and Vertebral Tuberculosis Secondary to <i>Mycobacterium Africanum</i> in an Immunocompetent Young Adult in a Low-Incidence Setting: Diagnostic Value of Middle Ear Biopsy.","authors":"Sabirah N Kasule, George S Zacharia, Abelard C Desrosiers, Shalini Penikilapate, Marcos A Molina, Srinivasan Krishna, Cosmina B Zeana","doi":"10.1155/crdi/5812867","DOIUrl":"10.1155/crdi/5812867","url":null,"abstract":"<p><p>Otic tuberculosis is an exceedingly rare manifestation of extrapulmonary tuberculosis (EPTB) and typically mimics more common otologic conditions, leading to delayed diagnosis and treatment. This report discusses a case of middle ear tuberculosis in a New York City-born-and-raised young woman. She presented with ear drainage, hearing loss, generalized weakness, and a painful lump on her posterior neck. She was subsequently diagnosed with multiple abscesses along the cervical and thoracic spine and a large mass in her middle ear that protruded through her tympanic membrane into the external auditory canal. Biopsy of the protruding part of the ear mass revealed non-necrotizing granulomatous inflammation and acid-fast bacilli on pathology. <i>Mycobacterium tuberculosis</i> (MTB) complex PCR was positive, and mycobacterial cultures grew <i>Mycobacterium africanum</i>. She was promptly initiated on rifampin, isoniazid, pyrazinamide, and ethambutol (RIPE) with clinical improvement of her symptoms.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"5812867"},"PeriodicalIF":0.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purulent MRSA Pericarditis Secondary to Chronic Diabetic Foot Osteomyelitis: A Case Report.","authors":"Maya Itani, Gustavo Rivera-Alvarez","doi":"10.1155/crdi/7744624","DOIUrl":"10.1155/crdi/7744624","url":null,"abstract":"<p><p>Purulent pericardial effusion is a rare but life-threatening manifestation of bacterial infection, most commonly caused by Staphylococcus aureus bacteremia. We report the case of an 86-year-old female with chronic diabetic foot osteomyelitis complicated by persistent methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) bacteremia. The patient subsequently developed purulent pericarditis, bilateral exudative pleural effusions, septic shock, and acute renal failure requiring continuous renal replacement therapy (CRRT) after intolerance to intermittent hemodialysis due to refractory hypotension. Despite broad-spectrum antimicrobial therapy and drainage of infected compartments, the patient developed refractory multiorgan failure and expired on hospital Day 26. This case highlights the high mortality associated with purulent pericarditis in the setting of persistent bacteremia and delayed source control.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"7744624"},"PeriodicalIF":0.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Presentation of HHV-7 Meningitis in a Nonimmunocompromised Adult: A Case Report and Literature Review.","authors":"Ismail Al Hajj, Sara Farhat, Ghenwa El Dakdouki","doi":"10.1155/crdi/8512795","DOIUrl":"10.1155/crdi/8512795","url":null,"abstract":"<p><strong>Background: </strong>Human herpesvirus-7 (HHV-7) is a member of the herpesvirus family that is commonly asymptomatic during infection, but it can lead to the development of exanthema subitum. Although HHV-7 primarily affects children and establishes latency in the body, reactivation of HHV-7 can occur in individuals with compromised immune systems and those using immunosuppressive medications, resulting in diverse clinical manifestations. However, the acute HHV-7 presentation in immunocompetent adults is uncommon.</p><p><strong>Case presentation: </strong>Here, we report a rare presentation of HHV-7 meningitis in an immunocompetent adult.</p><p><strong>Conclusion: </strong>This case report should raise concern about the atypical presentation of HHV-7 infection in an immunocompetent adult host, suggesting the urge to expand investigation on the pathogenicity of HHV-7 for better understanding of the mechanism of infection, early clinical intervention, and avoidance of further manifestations and death.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"8512795"},"PeriodicalIF":0.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Fatal <i>Balamuthia mandrillaris</i> Encephalitis in a Pediatric Patient: Diagnostic Challenges.","authors":"Isabella Amado, Yukta Italia, Rebecca Luke, Mary Suzanne Whitworth","doi":"10.1155/crdi/5594656","DOIUrl":"https://doi.org/10.1155/crdi/5594656","url":null,"abstract":"<p><p><i>Balamuthia mandrillaris</i> is a rare and lethal amoeba that causes granulomatous amoebic encephalitis (GAE), a severe brain infection with a high mortality rate. This manuscript presents a case study of a 5-year-old female patient with <i>B. mandrillaris</i> amoebic encephalitis. She presented from an outside hospital (OSH) with daily fevers, fatigue, and worsening mental status. She was without comorbidities, and sick contacts were denied. Diagnosis was challenging due to nonspecific encephalitis symptoms and nonspecific neurological imaging. Neuroimaging revealed symmetric diffuse restriction in the medial aspect of the basal ganglia. Autoimmune antibody testing was unrevealing. Amoebic encephalitis was considered when exhaustive testing was negative. Treatment with antiamoebic agents was initiated while free-living amoebic PCR panel was pending. The diagnosis was confirmed through PCR testing on cerebrospinal fluid (CSF), highlighting the importance of molecular techniques in diagnosing <i>B. mandrillaris</i> infections. After confirmation, treatment was updated per CDC recommendations. However, her condition continued to worsen, with progression of hemorrhage, ventriculomegaly, and ultimately herniation. Unfortunately, devastating neurological damage to the brainstem had already occurred, leading to brain death. Early recognition and accurate diagnosis are crucial for timely treatment and prevention of mortality by <i>B. mandrillaris</i> encephalitis. The application of molecular techniques offers promising advancements in this field.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"5594656"},"PeriodicalIF":0.8,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disseminated Herpes Simplex Virus Infection Presenting With Cytopenias in a Patient With Untreated Rheumatoid Arthritis.","authors":"Malvika Gupta, Christopher Graham","doi":"10.1155/crdi/3786322","DOIUrl":"https://doi.org/10.1155/crdi/3786322","url":null,"abstract":"<p><strong>Background: </strong>Disseminated herpes simplex virus (HSV) infection is an uncommon but serious condition, typically seen in immunocompromised hosts. Cytopenias, including neutropenia and thrombocytopenia, are rare manifestations, particularly in patients not actively receiving immunosuppressive therapy.</p><p><strong>Case presentation: </strong>We report a 75-year-old female with a history of rheumatoid arthritis (RA), previously on methotrexate and low-dose prednisone, who presented with painful oral and genital ulcers, mucositis, and rapidly progressive bicytopenia (neutropenia and thrombocytopenia). Her recent brief reinitiation of methotrexate prompted evaluation for drug-induced cytopenias; however, methotrexate levels were undetectable. Extensive infectious, nutritional, rheumatologic, and hematologic workup revealed HSV positivity from oral and inguinal ulcers. Bone marrow biopsy showed no evidence of hematologic malignancy or aplasia. She was treated with intravenous acyclovir, leading to clinical improvement and recovery of blood counts.</p><p><strong>Discussion: </strong>This case highlights the diagnostic complexity of cytopenias in patients with autoimmune diseases. While methotrexate toxicity and Felty's syndrome were initially considered, the clinical trajectory and lack of supportive findings redirected focus to infectious causes. Disseminated HSV infection causing cytopenias is rare and often overlooked in immunocompetent or intermittently immunosuppressed patients. In this patient, immune dysregulation due to underlying RA and advanced age likely contributed to HSV dissemination and bone marrow suppression.</p><p><strong>Conclusion: </strong>Clinicians should maintain a high index of suspicion for disseminated HSV in patients with autoimmune diseases presenting with mucocutaneous lesions and cytopenias, even in the absence of significant immunosuppressive therapy. Prompt recognition and antiviral therapy are critical to prevent complications and improve outcomes.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"3786322"},"PeriodicalIF":0.8,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Usual Suspects: A Challenging Case of Disseminated Sporotrichosis Masquerading as Suppurative Lymphadenitis in a Dialysis-Dependent Chronic Kidney Disease Patient With Lupus.","authors":"Natalia Chilinque Zambão da Silva, Jordanna de Paula Mendes Torres, Valéria Regina Soares, Nathalia Antônio de Oliveira Velasco, Violeta Duarte Tortelly Costa, Bruno Carrilho Hollanda","doi":"10.1155/crdi/2428389","DOIUrl":"10.1155/crdi/2428389","url":null,"abstract":"<p><p>Sporotrichosis, a subcutaneous mycosis, can manifest as severe disseminated disease in immunocompromised hosts. This report describes a challenging case of extracutaneous sporotrichosis in a 28-year-old female with systemic lupus erythematosus (SLE) on immunosuppressive therapy, who also faced significant socioeconomic constraints. The patient initially presented to the emergency department with a painful right inguinal mass. Physical examination revealed a hemorrhagic lesion, and aspiration of the material was performed for culture, which returned negative. She was discharged but returned 2 months later with worsening symptoms and widespread lesions. During this second admission, a detailed history finally revealed contact with cats. The patient was readmitted for an inguinal lymph node biopsy. Histopathological analysis revealed granulomatous lymphadenitis with stellate necrosis, and the diagnosis was ultimately confirmed by culture, identifying <i>Sporothrix schenckii</i> complex. Treatment with itraconazole was initiated but later switched to liposomal amphotericin B due to hepatotoxicity. The patient completed a 1-year course of liposomal amphotericin B with an excellent clinical response. This case highlights the diagnostic complexity of sporotrichosis in patients with SLE, its potential for severe dissemination, and the impact of socioeconomic barriers on timely diagnosis and disease management.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"2428389"},"PeriodicalIF":0.8,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Bacterial-Fungal Splenic Abscess in an Immunocompetent Host: <i>Salmonella Paratyphi A</i> and <i>Candida tropicalis</i> Co-Infection.","authors":"Kapil Chahal, Neha Rastogi, Swati Bhayana, Amit Javed, Rinkesh Kumar Bansal, Zubin Dev Sharma, Saurabh Kumar, Narola Yanger, Neha Lal, Shrinidhi Nathany, Vikas Dua, Rahul Bhargava","doi":"10.1155/crdi/3533752","DOIUrl":"https://doi.org/10.1155/crdi/3533752","url":null,"abstract":"<p><p>Splenic abscess is a rare but potentially life-threatening condition, most frequently seen in immunocompromised individuals or those with significant underlying comorbidities. Monomicrobial bacterial infections predominate, whereas fungal or mixed infections are uncommon, particularly in immunocompetent hosts. Concurrent bacterial and fungal infection of the spleen is exceedingly rare. We report the case of a 30-year-old immunocompetent Indian male who presented with high-grade fever, left upper quadrant abdominal pain, and gastrointestinal symptoms. Imaging demonstrated a multiseptated cystic lesion in the upper pole of the spleen consistent with abscess formation. Endoscopic ultrasound-guided fine-needle aspiration yielded purulent material, and culture revealed dual infection with <i>Salmonella enterica</i> serovar Paratyphi A and <i>Candida tropicalis</i>. Blood cultures and tuberculosis workup were negative. Despite broad-spectrum empirical antimicrobial therapy, radiological progression necessitated laparoscopic drainage and debridement, followed by culture-directed antibacterial therapy for a total of 5 weeks and antifungal therapy for 6 weeks. The patient achieved complete clinical and radiological resolution with preservation of splenic function. This case highlights the importance of maintaining a high index of clinical suspicion for splenic abscess and considering polymicrobial infection, including fungal pathogens, even in immunocompetent patients. Prompt microbiological diagnosis, early multidisciplinary involvement, timely spleen-sparing source control, and targeted antimicrobial therapy guided by susceptibility testing facilitated successful organ preservation while avoiding splenectomy, ultimately resulting in a favorable clinical outcome.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"3533752"},"PeriodicalIF":0.8,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13635971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Varicella Zoster Virus-Associated Meningoradiculitis in an Elderly Patient: A Case Report.","authors":"Yi Ru Tan, Samuel Zheng Fong Goh, Yeow Hoay Koh, Gabriel Shih Chung Yiin","doi":"10.1155/crdi/9461187","DOIUrl":"https://doi.org/10.1155/crdi/9461187","url":null,"abstract":"<p><strong>Introduction: </strong>Motor complication in immunocompetent individuals with varicella zoster virus (VZV) reactivation is uncommon and may mimic a compressive spinal disorder.</p><p><strong>Case presentation: </strong>A 77-year-old immunocompetent woman presented with an acute left foot drop preceded by coryzal symptoms and lower back pain. A vesicular rash developed over the left foot one week after the weakness began. Examination showed a predominantly severe left ankle dorsiflexion weakness with reduced sensation over the L5 and S1 dermatomes. A noncontrast magnetic resonance imaging (MRI) of the lumbosacral spine showed noncompressive degenerative changes. Cerebrospinal fluid (CSF) analysis showed lymphocytic pleocytosis, elevated protein, a reduced CSF-to-serum glucose ratio, and isolated VZV DNA on the polymerase chain reaction (PCR). VZV DNA was also detected from a vesicle swab. She received 14 days of intravenous acyclovir with neuropathic analgesia. A nerve conduction study and electromyography (NCS/EMG) at three months showed a severe left common peroneal neuropathy with sciatic nerve involvement. There was an initial slow motor recovery with persisting neuropathic pain, but only a residual moderate ankle dorsiflexion weakness remained at 9 months.</p><p><strong>Discussion: </strong>The combination of preceding radicular pain, vesicular rash, significant leg weakness, and positive VZV DNA in CSF and vesicle specimen supported a diagnosis of VZV-associated meningoradiculitis. The NCS/EMG was consistent with an evolution of VZV involvement at multiple neuraxial levels into a predominantly peripheral neuropathy. This diagnosis is easily missed when radicular pain precedes or occurs without a rash and when imaging is disproportionate to the severity of deficit. CSF PCR and skin lesion sampling are central to an early diagnosis.</p><p><strong>Conclusion: </strong>VZV should be considered in patients with acute painful radiculopathy with significant limb weakness that is out of proportion to imaging findings, even without immunosuppression or an early rash. Early antiviral therapy can limit disability, although residual neurological deficits and pain may persist.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"9461187"},"PeriodicalIF":0.8,"publicationDate":"2026-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13635784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Tetanus in an Older Adult Without an Identifiable Portal of Entry: A Case Report.","authors":"Yanwei Rao, Wei He, Yang Yu, Yicheng Wang, Yuan Yuan, Yongjie Wang","doi":"10.1155/crdi/3340319","DOIUrl":"10.1155/crdi/3340319","url":null,"abstract":"<p><p>Tetanus remains a significant health concern, particularly in older adults with waning immunity. The diagnosis is typically clinical, based on characteristic features such as trismus, muscle rigidity, and stimulus-triggered spasms. However, diagnostic challenges arise when tetanus presents without an identifiable acute wound or with an occult portal of entry, as it may be misattributed to more common neurological conditions such as stroke or encephalitis. We report a 65-year-old Chinese male who presented with 15-day cough and sputum, followed by acute trismus and dysphagia. Initial evaluation at a local hospital suggested cerebral infarction, but treatment with neuroprotective agents yielded no improvement. The patient was transferred to a tertiary hospital, where he developed generalized spasms and respiratory distress requiring mechanical ventilation. Extensive neurological investigation revealed only chronic ischemic changes; encephalitis was considered but not confirmed. Subsequent consultation identified characteristic features including trismus, risus sardonicus, opisthotonos, stimulus-triggered spasms, and preserved consciousness during spasms, leading to diagnosis of severe tetanus (Ablett Grade IV, based on severe generalized spasms, respiratory failure requiring mechanical ventilation, and autonomic dysfunction requiring vasopressor support). No acute wound was identified on full-body examination; only remote facial burns and scarring from > 20 years prior was noted. The patient received human tetanus immunoglobulin, intensive sedation and analgesia, mechanical ventilation, and supportive care. After 28 ICU days, the patient was successfully weaned from ventilation, achieved complete spasm resolution, and was transferred to a general ward for rehabilitation. This case demonstrates that severe generalized tetanus should remain in the differential diagnosis of older adults presenting with acute trismus, dysphagia, muscle rigidity, or stimulus-triggered spasms, even when recent trauma is not recalled and no active wound is visible. Clinicians should obtain a thorough exposure history, perform repeated full-body examinations, and initiate timely antitoxin administration and ICU-based supportive care. The absence of an identifiable portal of entry should not delay diagnosis or treatment.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"3340319"},"PeriodicalIF":0.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fecal Microbiota Transplantation as a Rescue Therapy for Refractory <i>Clostridioides difficile</i> Infection in a Patient With Lupus.","authors":"Miguel Alejandro Pinzón, Juan Felipe Betancur, Andrea Paola Sierra Bolaño, Julio Andrés Boada-Garnica, Juan Felipe Llano, Beatriz Ramírez","doi":"10.1155/crdi/7694915","DOIUrl":"10.1155/crdi/7694915","url":null,"abstract":"<p><p><i>Clostridioides difficile</i> infection (CDI) remains a major clinical challenge, particularly when it is refractory or recurrent. We describe a 68-year-old woman with systemic lupus erythematosus and other comorbidities who developed fulminant refractory CDI, characterized by ileus and persistent symptoms despite a course of oral vancomycin. She presented with abdominal pain, bilious vomiting, and high-volume diarrhea. Stool testing detected <i>C. difficile</i> toxins A and B, and imaging showed bowel dilatation, mucosal thickening, and lymphadenopathy. Despite 18 days of oral vancomycin and intravenous metronidazole, she showed no clinical improvement. A single fecal microbiota transplantation (FMT) was therefore performed as rescue therapy. Diarrhea resolved completely within 3 days, with no CDI recurrence or FMT-related adverse events during 12 months of follow-up. This case illustrates the potential role of FMT as rescue therapy for fulminant refractory CDI in selected immunocompromised patients. Careful donor screening and close clinical monitoring remain essential, and further research is needed to define the long-term safety of FMT in patients with autoimmune diseases.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"7694915"},"PeriodicalIF":0.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}