Anna DeFrank, Michael Bosco, Sigridh Muñoz Gómez, Amit Dhaliwal
{"title":"WATCHMAN植入术后耐头孢地考依氏杆菌血症1例报告及文献复习。","authors":"Anna DeFrank, Michael Bosco, Sigridh Muñoz Gómez, Amit Dhaliwal","doi":"10.1155/crdi/5221364","DOIUrl":null,"url":null,"abstract":"<p><p><i>Elizabethkingia anophelis</i> is an emerging pathogen associated with nosocomial and community outbreaks. Treatment of infection caused by <i>E. anophelis</i> is not well-defined given its extensive drug resistance profile, and infection carries a poor prognosis. <i>E. anophelis</i> is intrinsically resistant to many classes of antibiotics including carbapenems and polymyxins due to multiple resistance genes. Resistance to novel β-lactam/β-lactamase inhibitors has also been reported. The activity of cefiderocol (FDC) is unknown. Here, we describe a case of FDC-resistant <i>E. anophelis</i> bacteremia following WATCHMAN implantation. To our knowledge, this is the first reported case of FDC resistance amongst <i>Elizabethkingia</i> spp.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"5221364"},"PeriodicalIF":1.0000,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12116131/pdf/","citationCount":"0","resultStr":"{\"title\":\"Cefiderocol-Resistant <i>Elizabethkingia anophelis</i> Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature.\",\"authors\":\"Anna DeFrank, Michael Bosco, Sigridh Muñoz Gómez, Amit Dhaliwal\",\"doi\":\"10.1155/crdi/5221364\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Elizabethkingia anophelis</i> is an emerging pathogen associated with nosocomial and community outbreaks. Treatment of infection caused by <i>E. anophelis</i> is not well-defined given its extensive drug resistance profile, and infection carries a poor prognosis. <i>E. anophelis</i> is intrinsically resistant to many classes of antibiotics including carbapenems and polymyxins due to multiple resistance genes. Resistance to novel β-lactam/β-lactamase inhibitors has also been reported. The activity of cefiderocol (FDC) is unknown. Here, we describe a case of FDC-resistant <i>E. anophelis</i> bacteremia following WATCHMAN implantation. To our knowledge, this is the first reported case of FDC resistance amongst <i>Elizabethkingia</i> spp.</p>\",\"PeriodicalId\":9608,\"journal\":{\"name\":\"Case Reports in Infectious Diseases\",\"volume\":\"2025 \",\"pages\":\"5221364\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-05-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12116131/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Infectious Diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/crdi/5221364\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crdi/5221364","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature.
Elizabethkingia anophelis is an emerging pathogen associated with nosocomial and community outbreaks. Treatment of infection caused by E. anophelis is not well-defined given its extensive drug resistance profile, and infection carries a poor prognosis. E. anophelis is intrinsically resistant to many classes of antibiotics including carbapenems and polymyxins due to multiple resistance genes. Resistance to novel β-lactam/β-lactamase inhibitors has also been reported. The activity of cefiderocol (FDC) is unknown. Here, we describe a case of FDC-resistant E. anophelis bacteremia following WATCHMAN implantation. To our knowledge, this is the first reported case of FDC resistance amongst Elizabethkingia spp.
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